Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

T. Hosoya · SciRah

Researcher profile · Semantic Scholar

T. Hosoya

Share profile

T. Hosoya — researcher profile on SciRah

h-index: 55
Works: 462
Citations: 13K

Most-cited papers

Decreased extra-renal urate excretion is a common cause of hyperuricemia
K. Ichida, H. Matsuo, T. Takada, A. Nakayama +20 more
2012Nature Communications654 citations Open access
Semantic Scholar
Febuxostat Therapy for Patients With Stage 3 CKD and Asymptomatic Hyperuricemia: A Randomized Trial.
K. Kimura, T. Hosoya, S. Uchida, M. Inaba +70 more
2018American Journal of Kidney Diseases353 citations Open access
Semantic Scholar
Genome-wide association study of clinically defined gout identifies multiple risk loci and its association with clinical subtypes
H. Matsuo, Ken Yamamoto, H. Nakaoka, A. Nakayama +36 more
2015Annals of the Rheumatic Diseases169 citations Open access
Semantic Scholar
ABCG2 dysfunction causes hyperuricemia due to both renal urate underexcretion and renal urate overload
H. Matsuo, A. Nakayama, M. Sakiyama, Toshinori Chiba +23 more
2014Scientific Reports168 citations Open access
Semantic Scholar
Effects of topiroxostat on the serum urate levels and urinary albumin excretion in hyperuricemic stage 3 chronic kidney disease patients with or without gout
T. Hosoya, I. Ohno, Shinsuke Nomura, I. Hisatome +4 more
2014Clinical and Experimental Nephrology149 citations Open access
Semantic Scholar
Common dysfunctional variants in ABCG2 are a major cause of early-onset gout
H. Matsuo, K. Ichida, T. Takada, A. Nakayama +25 more
2013Scientific Reports132 citations Open access
Semantic Scholar
GWAS of clinically defined gout and subtypes identifies multiple susceptibility loci that include urate transporter genes
A. Nakayama, H. Nakaoka, Ken Yamamoto, M. Sakiyama +42 more
2016Annals of the Rheumatic Diseases128 citations Open access
Semantic Scholar
A higher serum alkaline phosphatase is associated with the incidence of hip fracture and mortality among patients receiving hemodialysis in Japan.
Yukio Maruyama, Masatomo Taniguchi, J. Kazama, K. Yokoyama +5 more
2014Nephrology, Dialysis and Transplantation106 citations
Semantic Scholar
Low glomerular density with glomerulomegaly in obesity-related glomerulopathy.
N. Tsuboi, Y. Utsunomiya, Go Kanzaki, K. Koike +3 more
2012American Society of Nephrology. Clinical Journal97 citations
Semantic Scholar
Genome-wide association study revealed novel loci which aggravate asymptomatic hyperuricaemia into gout
Yusuke Kawamura, H. Nakaoka, A. Nakayama, Y. Okada +45 more
2019Annals of the Rheumatic Diseases84 citations Open access
Semantic Scholar
Common dysfunctional variants of ABCG2 have stronger impact on hyperuricemia progression than typical environmental risk factors
A. Nakayama, H. Matsuo, H. Nakaoka, Takahiro Nakamura +20 more
2014Scientific Reports84 citations Open access
Semantic Scholar
Effect of Oral Alfacalcidol on Clinical Outcomes in Patients Without Secondary Hyperparathyroidism Receiving Maintenance Hemodialysis: The J-DAVID Randomized Clinical Trial
T. Shoji, M. Inaba, M. Fukagawa, R. Ando +57 more
2018Journal of the American Medical Association (JAMA)75 citations Open access
Semantic Scholar
Safety, efficacy and renal effect of febuxostat in patients with moderate-to-severe kidney dysfunction
Y. Shibagaki, I. Ohno, T. Hosoya, K. Kimura
2014Hypertension Research74 citations Open access
Semantic Scholar
The effect of febuxostat to prevent a further reduction in renal function of patients with hyperuricemia who have never had gout and are complicated by chronic kidney disease stage 3: study protocol for a multicenter randomized controlled study
T. Hosoya, K. Kimura, Sadayoshi Itoh, M. Inaba +11 more
2014Trials73 citations Open access
Semantic Scholar
Clinical features and long-term renal outcomes of Japanese patients with obesity-related glomerulopathy
N. Tsuboi, K. Koike, K. Hirano, Y. Utsunomiya +2 more
2013Clinical and Experimental Nephrology63 citations
Semantic Scholar
Multiple common and rare variants of ABCG2 cause gout
T. Higashino, T. Takada, H. Nakaoka, Y. Toyoda +24 more
2017RMD Open61 citations Open access
Semantic Scholar
Uric acid-lowering and renoprotective effects of topiroxostat, a selective xanthine oxidoreductase inhibitor, in patients with diabetic nephropathy and hyperuricemia: a randomized, double-blind, placebo-controlled, parallel-group study (UPWARD study)
T. Wada, T. Hosoya, D. Honda, R. Sakamoto +4 more
2018Clinical and Experimental Nephrology59 citations Open access
Semantic Scholar
Comparison of topiroxostat and allopurinol in Japanese hyperuricemic patients with or without gout: a phase 3, multicentre, randomized, double‐blind, double‐dummy, active‐controlled, parallel‐group study
T. Hosoya, Y. Ogawa, H. Hashimoto, T. Ohashi +1 more
2016Journal of Clinical Pharmacy and Therapeutics57 citations Open access
Semantic Scholar
Xenotransplanted Embryonic Kidney Provides a Niche for Endogenous Mesenchymal Stem Cell Differentiation into Erythropoietin‐Producing Tissue
Kei Matsumoto, T. Yokoo, H. Matsunari, Satomi Iwai +10 more
2012Stem Cells50 citations
Semantic Scholar
Clinical efficacy and safety of topiroxostat in Japanese hyperuricemic patients with or without gout: a randomized, double-blinded, controlled phase 2b study
T. Hosoya, Tomomitsu Sasaki, T. Ohashi
2016Clinical Rheumatology48 citations Open access
Semantic Scholar
Subtype-specific gout susceptibility loci and enrichment of selection pressure on ABCG2 and ALDH2 identified by subtype genome-wide meta-analyses of clinically defined gout patients
A. Nakayama, M. Nakatochi, Yusuke Kawamura, Ken Yamamoto +50 more
2020Annals of the Rheumatic Diseases47 citations Open access
Semantic Scholar
ABCG2 Dysfunction Increases the Risk of Renal Overload Hyperuricemia
H. Matsuo, T. Takada, A. Nakayama, Toru Shimizu +10 more
2014Nucleosides, Nucleotides & Nucleic Acids45 citations
Semantic Scholar
Obesity-related glomerulopathy and the nephron complement.
N. Tsuboi, Y. Utsunomiya, T. Hosoya
2013Nephrology, Dialysis and Transplantation44 citations Open access
Semantic Scholar
Dotinurad versus benzbromarone in Japanese hyperuricemic patient with or without gout: a randomized, double-blind, parallel-group, phase 3 study
T. Hosoya, T. Sano, Tomomitsu Sasaki, M. Fushimi +1 more
2020Clinical and Experimental Nephrology43 citations Open access
Semantic Scholar
Dotinurad: a novel selective urate reabsorption inhibitor for the treatment of hyperuricemia and gout
T. Ishikawa, Toshinari Takahashi, Tetsuya Taniguchi, T. Hosoya
2021Expert Opinion on Pharmacotherapy41 citations Open access
Semantic Scholar
Serum uric acid and the incidence of CKD and hypertension
S. Kuriyama, Yukio Maruyama, Shinichiro Nishio, Yasuhito Takahashi +6 more
2015Clinical and Experimental Nephrology41 citations Open access
Semantic Scholar
Keap1 inhibition attenuates glomerulosclerosis.
Y. Miyazaki, A. Shimizu, I. Pastan, K. Taguchi +8 more
2014Nephrology, Dialysis and Transplantation40 citations Open access
Semantic Scholar
Clinical efficacy and safety of topiroxostat in Japanese male hyperuricemic patients with or without gout: an exploratory, phase 2a, multicentre, randomized, double‐blind, placebo‐controlled study
T. Hosoya, T. Sasaki, H. Hashimoto, R. Sakamoto +1 more
2016Journal of Clinical Pharmacy and Therapeutics39 citations Open access
Semantic Scholar
A comprehensive search for mutations in the PKD1 and PKD2 in Japanese subjects with autosomal dominant polycystic kidney disease
Mahiro Kurashige, K. Hanaoka, M. Imamura, T. Udagawa +5 more
2015Clinical Genetics36 citations
Semantic Scholar
The effect of metanephros transplantation on blood pressure in anephric rats with induced acute hypotension.
S. Yokote, T. Yokoo, Kei Matsumoto, Y. Utsunomiya +2 more
2012Nephrology, Dialysis and Transplantation34 citations Open access
Semantic Scholar
A non-inferiority study of the novel selective urate reabsorption inhibitor dotinurad versus febuxostat in hyperuricemic patients with or without gout
T. Hosoya, K. Furuno, S. Kanda
2020Clinical and Experimental Nephrology33 citations Open access
Semantic Scholar
Distribution of glomerular density in different cortical zones of the human kidney
Go Kanzaki, N. Tsuboi, Y. Utsunomiya, M. Ikegami +2 more
2013Pathology international (Print)33 citations
Semantic Scholar
Open-label study of long-term administration of dotinurad in Japanese hyperuricemic patients with or without gout
T. Hosoya, M. Fushimi, D. Okui, Tomomitsu Sasaki +1 more
2019Clinical and Experimental Nephrology32 citations Open access
Semantic Scholar
Urate-lowering therapy for CKD patients with asymptomatic hyperuricemia without proteinuria elucidated by attribute-based research in the FEATHER Study
H. Kataoka, T. Mochizuki, Mamiko Ohara, Yuki Tsuruta +74 more
2022Scientific Reports31 citations Open access
Semantic Scholar
The Influence of a Single Nucleotide Polymorphism within CNDP1 on Susceptibility to Diabetic Nephropathy in Japanese Women with Type 2 Diabetes
Mahiro Kurashige, Minako Imamura, S. Araki, D. Suzuki +11 more
2013PLoS ONE30 citations Open access
Semantic Scholar
The predictive value of attenuated proteinuria at 1 year after steroid therapy for renal survival in patients with IgA nephropathy
K. Hirano, T. Kawamura, N. Tsuboi, H. Okonogi +7 more
2012Clinical and Experimental Nephrology29 citations Open access
Semantic Scholar
Combined Therapy with Peritoneal Dialysis and Hemodialysis: A Multicenter Retrospective Observational Cohort Study in Japan
Yukio Maruyama, K. Yokoyama, M. Nakayama, C. Higuchi +10 more
2014Blood Purification28 citations
Semantic Scholar
Clinical efficacy and safety of dotinurad, a novel selective urate reabsorption inhibitor, in Japanese hyperuricemic patients with or without gout: randomized, multicenter, double-blind, placebo-controlled, parallel-group, confirmatory phase 2 study
T. Hosoya, T. Sano, Tomomitsu Sasaki, M. Fushimi +1 more
2019Clinical and Experimental Nephrology26 citations Open access
Semantic Scholar
Gender interaction of uric acid in the development of hypertension
Shinichiro Nishio, Yukio Maruyama, Naoki Sugano, T. Hosoya +2 more
2018Clinical and experimental hypertension24 citations
Semantic Scholar
Interactions between Serum Vitamin D Levels and Vitamin D Receptor Gene FokI Polymorphisms for Renal Function in Patients with Type 2 Diabetes
K. Yokoyama, A. Nakashima, M. Urashima, Hiroaki Suga +14 more
2012PLoS ONE23 citations Open access
Semantic Scholar
Mice are unable to endogenously regenerate podocytes during the repair of immunotoxin-induced glomerular injury.
Y. Miyazaki, A. Shimizu, I. Ichikawa, T. Hosoya +2 more
2014Nephrology, Dialysis and Transplantation22 citations
Semantic Scholar
Clinical efficacy and safety of dotinurad, a novel selective urate reabsorption inhibitor, in Japanese hyperuricemic patients with or without gout: an exploratory, randomized, multicenter, double-blind, placebo-controlled, parallel-group early phase 2 study
T. Hosoya, T. Sano, Tomomitsu Sasaki, M. Fushimi +1 more
2019Clinical and Experimental Nephrology20 citations Open access
Semantic Scholar
Acute neutropenia associated with initiation of febuxostat therapy for hyperuricaemia in patients with chronic kidney disease
S. Kobayashi, M. Ogura, T. Hosoya
2013Journal of Clinical Pharmacy and Therapeutics20 citations Open access
Semantic Scholar
Factors related to the glomerular size in renal biopsies of chronic kidney disease patients.
N. Tsuboi, Y. Utsunomiya, K. Koike, Go Kanzaki +7 more
2013Clinical Nephrology20 citations
Semantic Scholar
Replication study for the association of 3 SNP loci identified in a genome-wide association study for diabetic nephropathy in European type 1 diabetes with diabetic nephropathy in Japanese patients with type 2 diabetes
S. Maeda, Minako Imamura, Mahiro Kurashige, S. Araki +11 more
2013Clinical and Experimental Nephrology19 citations
Semantic Scholar
Multicenter, Open-Label Study of Long-Term Topiroxostat (FYX-051) Administration in Japanese Hyperuricemic Patients with or Without Gout
T. Hosoya, T. Ishikawa, Y. Ogawa, R. Sakamoto +1 more
2018Clinical drug investigation17 citations Open access
Semantic Scholar
Diffuse tubulointerstitial nephritis accompanied by renal crystal formation in an HIV-infected patient undergoing highly active antiretroviral therapy.
Go Kanzaki, N. Tsuboi, Y. Miyazaki, T. Yokoo +2 more
2012Internal medicine17 citations Open access
Semantic Scholar
Unroofing Surgery with en Bloc Resection of the Skin and Tissues Around the Peripheral Cuff
H. Terawaki, H. Nakano, M. Ogura, Moritoshi Kadomura +2 more
2013Peritoneal Dialysis International16 citations Open access
Semantic Scholar
Risk Factors for Encapsulating Peritoneal Sclerosis in Long‐Term Peritoneal Dialysis: A Retrospective Observational Study
Masatsugu Nakao, K. Yokoyama, I. Yamamoto, Nanae Matsuo +6 more
2014Therapeutic apheresis and dialysis15 citations Open access
Semantic Scholar
Apoptosis induced by an uromodulin mutant C112Y and its suppression by topiroxostat
S. Utami, E. Mahati, Pei-Li Li, N. Maharani +15 more
2015Clinical and Experimental Nephrology12 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

K. Ichida×11
Invite
K. Ichida — researcher profile on SciRah
H. Matsuo×10
Invite
H. Matsuo — researcher profile on SciRah
T. Takada×10
Invite
T. Takada — researcher profile on SciRah
A. Nakayama×10
Invite
A. Nakayama — researcher profile on SciRah

×10

Invite

H. Nakashima — researcher profile on SciRah

Takahiro Nakamura×10

Invite

Takahiro Nakamura — researcher profile on SciRah

N. Shinomiya×10

Invite

N. Shinomiya — researcher profile on SciRah

Yusuke Kawamura×9

Invite

Yusuke Kawamura — researcher profile on SciRah

Seiko Shimizu×9

Invite

Seiko Shimizu — researcher profile on SciRah

Invite

T. Yokoo — researcher profile on SciRah

Y. Utsunomiya×9

Invite

Y. Utsunomiya — researcher profile on SciRah

Toru Shimizu×8

Invite

Toru Shimizu — researcher profile on SciRah