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R. Sakamoto · SciRah

Researcher profile · Semantic Scholar

R. Sakamoto

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R. Sakamoto — researcher profile on SciRah

h-index: 6
Works: 8
Citations: 266

Most-cited papers

Effects of topiroxostat and febuxostat on urinary albumin excretion and plasma xanthine oxidoreductase activity in db/db mice.
Takashi Nakamura, T. Murase, Mai Nampei, N. Morimoto +3 more
2016European Journal of Pharmacology78 citations
Semantic Scholar
Uric acid-lowering and renoprotective effects of topiroxostat, a selective xanthine oxidoreductase inhibitor, in patients with diabetic nephropathy and hyperuricemia: a randomized, double-blind, placebo-controlled, parallel-group study (UPWARD study)
T. Wada, T. Hosoya, D. Honda, R. Sakamoto +4 more
2018Clinical and Experimental Nephrology59 citations Open access
Semantic Scholar
Comparison of topiroxostat and allopurinol in Japanese hyperuricemic patients with or without gout: a phase 3, multicentre, randomized, double‐blind, double‐dummy, active‐controlled, parallel‐group study
T. Hosoya, Y. Ogawa, H. Hashimoto, T. Ohashi +1 more
2016Journal of Clinical Pharmacy and Therapeutics57 citations Open access
Semantic Scholar
Clinical efficacy and safety of topiroxostat in Japanese male hyperuricemic patients with or without gout: an exploratory, phase 2a, multicentre, randomized, double‐blind, placebo‐controlled study
T. Hosoya, T. Sasaki, H. Hashimoto, R. Sakamoto +1 more
2016Journal of Clinical Pharmacy and Therapeutics39 citations Open access
Semantic Scholar
Multicenter, Open-Label Study of Long-Term Topiroxostat (FYX-051) Administration in Japanese Hyperuricemic Patients with or Without Gout
T. Hosoya, T. Ishikawa, Y. Ogawa, R. Sakamoto +1 more
2018Clinical drug investigation17 citations Open access
Semantic Scholar
Xanthine oxidoreductase inhibitor topiroxostat ameliorates podocyte injury by inhibiting the reduction of nephrin and podoplanin.
Ying Zhang, Y. Fukusumi, Mutsumi Kayaba, Takashi Nakamura +3 more
2021Nefrología6 citations Open access
Semantic Scholar
Xanthine oxidoreductase inhibitor topiroxostat ameliorates podocyte injury by inhibiting the reduction of nephrin and podoplanin.
Ying Zhang, Y. Fukusumi, Mutsumi Kayaba, Takashi Nakamura +3 more
2021Nefrología6 citations Open access
Semantic Scholar
Topiroxostat Showed Renoprotection via Various Mechanisms Including Suppression of Xanthine Oxidoreductase-Induced-Oxidative Stress and Inflammation in db/db Mice
Takashi Nakamura, G. Nagao, Mai Nampei, T. Murase +4 more
20164 citations
Semantic Scholar

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