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P. Lipari · SciRah

Researcher profile · Semantic Scholar

P. Lipari

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P. Lipari — researcher profile on SciRah

h-index: 13
Works: 22
Citations: 1,089

Most-cited papers

Antitumor activity of SCH 66336, an orally bioavailable tricyclic inhibitor of farnesyl protein transferase, in human tumor xenograft models and wap-ras transgenic mice.
Ming Liu, M. Bryant, Jian-Ping Chen, Sui-Ning Lee +22 more
1998Cancer Research349 citations
Semantic Scholar
Inhibition of insulin-like growth factor-I receptor (IGF-IR) signaling and tumor cell growth by a fully human neutralizing anti–IGF-IR antibody
Yan Wang, J. Hailey, Denise Williams, Yao-Lin Wang +15 more
2005Molecular Cancer Therapeutics171 citations
Semantic Scholar
Adenovirus-mediated p53 gene therapy and paclitaxel have synergistic efficacy in models of human head and neck, ovarian, prostate, and breast cancer.
L. Nielsen, P. Lipari, J. Dell, M. Gurnani +1 more
1998Clinical Cancer Research135 citations
Semantic Scholar
Adenovirus-mediated p53 gene therapy has greater efficacy when combined with chemotherapy against human head and neck, ovarian, prostate, and breast cancer
M. Gurnani, P. Lipari, J. Dell, B. Shi +1 more
1999Cancer Chemotherapy and Pharmacology108 citations
Semantic Scholar
Fluorescence polarization assay and inhibitor design for MDM2/p53 interaction.
Ru-Min Zhang, T. Mayhood, P. Lipari, Yao-Lin Wang +5 more
2004Analytical Biochemistry55 citations Open access
Semantic Scholar
Effects of SCH 59228, an orally bioavailable farnesyl protein transferase inhibitor, on the growth of oncogene-transformed fibroblasts and a human colon carcinoma xenograft in nude mice
Ming Liu, M. Bryant, Jian-Ping Chen, Sui-Ning Lee +16 more
1999Cancer Chemotherapy and Pharmacology44 citations
Semantic Scholar
Combination therapy with the farnesyl protein transferase inhibitor SCH66336 and SCH58500 (p53 adenovirus) in preclinical cancer models.
L. Nielsen, B. Shi, G. Hajian, Bohden Yaremko +7 more
1999Cancer Research43 citations
Semantic Scholar
Structure-activity relationship of 3-substituted N-(pyridinylacetyl)-4- (8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene )- piperidine inhibitors of farnesyl-protein transferase: design and synthesis of in vivo active antitumor compounds.
F. Njoroge, Bancha Vibulbhan, Dinananth F. Rane, W. Bishop +19 more
1997Journal of Medicinal Chemistry43 citations Open access
Semantic Scholar
A Fully Human Insulin-Like Growth Factor-I Receptor Antibody SCH 717454 (Robatumumab) Has Antitumor Activity as a Single Agent and in Combination with Cytotoxics in Pediatric Tumor Xenografts
Yao-Lin Wang, P. Lipari, Xiao-Ying Wang, J. Hailey +6 more
2010Molecular Cancer Therapeutics42 citations Open access
Semantic Scholar
Toxin-Mediated Paracellular Transport of Antitoxin Antibodies Facilitates Protection against Clostridium difficile Infection
Zuo Zhang, Xinhua Chen, Lorraine D. Hernandez, P. Lipari +8 more
2014Infection and Immunity40 citations Open access
Semantic Scholar
Inhibitors of farnesyl protein transferase. 4-Amido, 4-carbamoyl, and 4-carboxamido derivatives of 1-(8-chloro-6,11-dihydro-5H-benzo[5,6]- cyclohepta[1,2-b]pyridin-11-yl)piperazine and 1-(3-bromo-8-chloro-6,11- dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl)piperazine.
Alan K. Mallams, Randall R. Rossman, R. Doll, Viyyoor M. Girijavallabhan +24 more
1998Journal of Medicinal Chemistry20 citations Open access
Semantic Scholar
Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors.
Stéphane L. Bogen, W. Pan, Craig R. Gibeau, Brian R. Lahue +22 more
2016ACS Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
Kibdelomycin Is a Potent and Selective Agent against Toxigenic Clostridium difficile
L. Miesel, D. Hecht, J. R. Osmolski, D. Gerding +9 more
2014Antimicrobial Agents and Chemotherapy15 citations Open access
Semantic Scholar
Adenovirus-mediated p 53 Gene Therapy and Paclitaxel Have Synergistic Efficacy in Models of Human Head and Neck , Ovarian , Prostate , and Breast Cancer
L. Nielsen, P. Lipari, J. Dell
20056 citations
Semantic Scholar
Evaluation of the Biodistribution, Efficacy, and Side-Effect Profile of Deflazacort, Prednisolone and Vamorolone in a DMD Mouse Model (S34.010)
Grace Liu, P. Lipari, A. Mollin, Stephen Jung +14 more
2023Wednesday, April 260 citations
Semantic Scholar
Correction for Zhang et al., Toxin-Mediated Paracellular Transport of Antitoxin Antibodies Facilitates Protection against Clostridium difficile Infection
Zuo Zhang, Xinhua Chen, Lorraine D. Hernandez, P. Lipari +8 more
2015Infection and Immunity0 citations Open access
Semantic Scholar
Abstract 2785: Discovery of a novel HDM2 inhibitor with potent in vivo anti-tumor activity
Yao-Lin Wang, P. Lipari, A. Mirza, Yinghui Lin +10 more
20120 citations
Semantic Scholar
Abstract 1536: Characterization of tumor cell lines selected for resistance to the HDM2 antagonist Nutlin-3a
Yao-Lin Wang, Xiao-Ying Wang, P. Lipari, David J Devlin +7 more
20100 citations
Semantic Scholar
Abstract 4533: In vivo activation of the p53 pathway leading to tumor regression by a novel and potent HDM2 antagonist SCH 1450206
Yao-Lin Wang, Xiao-Ying Wang, P. Lipari, A. Ponery +11 more
20100 citations
Semantic Scholar
Abstract 4534: A novel and potent small molecule antagonist of HDM2, SCH 1450206, activates the p53 pathway with mechanism-based activity
Su-Xing Liu, A. Mirza, Xiao-Ying Wang, P. Lipari +9 more
20100 citations
Semantic Scholar
Abstract A49: FDG‐PET as an imaging biomarker for the response of xenograft tumors to IGF‐1R inhibition
Yan Wang, Yao-Lin Wang, Xiao-Ying Wang, J. Hailey +3 more
20090 citations
Semantic Scholar
Un unexpected ring carboxylation in the electrocarboxylation of substituted aromatic ketones
O. Scialdone, M. Sabbatino, A. Galia, C. Belfiore +2 more
20040 citations
Semantic Scholar

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