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Takeshi Honda · SciRah

Researcher profile · Semantic Scholar

Takeshi Honda

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Takeshi Honda — researcher profile on SciRah

h-index: 23
Works: 61
Citations: 1,379

Most-cited papers

Novel antibody drug conjugates containing exatecan derivative-based cytotoxic payloads.
T. Nakada, T. Masuda, H. Naito, Masao Yoshida +8 more
2016Bioorganic & Medicinal Chemistry Letters147 citations
Semantic Scholar
Total Synthesis of Bleomycin A2 and Related Agents. 4. Synthesis of the Disaccharide Subunit 2-O-(3-O-Carbamoyl-.alpha.-D-mannopyranosyl)-L-gulopyranose and Completion of the Total Synthesis of Bleomycin A2
D. Boger, Takeshi Honda
199488 citations
Semantic Scholar
A rapid and efficient synthesis of 1,2-trans-β-linked glycosides via benzyl- or benzoyl-protected glycopyranosyl phosphates
S. Hashimoto, Takeshi Honda, S. Ikegami
198980 citations
Semantic Scholar
Total Synthesis of Bleomycin A2 and Related Agents. 1. Synthesis and DNA Binding Properties of the Extended C-Terminus: Tripeptide S, Tetrapeptide S, Pentapeptide S, and Related Agents
D. Boger, S. Colletti, Takeshi Honda, Royce F. Menezes
199465 citations
Semantic Scholar
Synthesis and anti-influenza virus activity of 7-O-alkylated derivatives related to zanamivir.
Takeshi Honda, T. Masuda, Shuku Yoshida, Masami Arai +2 more
2002Bioorganic & Medicinal Chemistry Letters59 citations Open access
Semantic Scholar
Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives.
T. Masuda, Shuku Yoshida, Masami Arai, S. Kaneko +2 more
2003Chemical and pharmaceutical bulletin53 citations Open access
Semantic Scholar
Synthesis and anti-influenza virus activity of 4-guanidino-7-substituted Neu5Ac2en derivatives.
Takeshi Honda, T. Masuda, Shuku Yoshida, Masami Arai +2 more
2002Bioorganic & Medicinal Chemistry Letters51 citations Open access
Semantic Scholar
“Armed-disarmed” glycosidation strategy based on glycosyl donors and acceptors carrying phosphoroamidate as a leaving group: A convergent synthesis of globotriaosylceramide
S. Hashimoto, H. Sakamoto, Takeshi Honda, H. Abe +2 more
199751 citations
Semantic Scholar
Synthesis and anti-influenza evaluation of orally active bicyclic ether derivatives related to zanamivir.
T. Masuda, S. Shibuya, Masami Arai, Shuku Yoshida +4 more
2003Bioorganic & Medicinal Chemistry Letters50 citations Open access
Semantic Scholar
Synthesis and anti-influenza evaluation of polyvalent sialidase inhibitors bearing 4-guanidino-Neu5Ac2en derivatives.
Takeshi Honda, Shuku Yoshida, Masami Arai, T. Masuda +1 more
2002Bioorganic & Medicinal Chemistry Letters49 citations
Semantic Scholar
Total Synthesis of Bleomycin A2 and Related Agents. 2. Synthesis of (-)-Pyrimidoblamic Acid, epi-(+)-Pyrimidoblamic Acid, (+)-Desacetamidopyrimidoblamic Acid, and (-)-Descarboxamidopyrimidoblamic Acid
D. Boger, Takeshi Honda, Q. Dang
199446 citations
Semantic Scholar
Synthesis and in vivo influenza virus-inhibitory effect of ester prodrug of 4-guanidino-7-O-methyl-Neu5Ac2en.
Takeshi Honda, S. Kubo, T. Masuda, Masami Arai +2 more
2009Bioorganic & Medicinal Chemistry Letters42 citations
Semantic Scholar
Total syntheses of (+)-P-3A, epi-(-)-P-3A, and (-)-desacetamido P-3A
D. Boger, Takeshi Honda, Royce F. Menezes, S. Colletti +2 more
199442 citations
Semantic Scholar
An efficient construction of 1,2-trans-β-glycosidic linkages capitalizing on glycopyranosyl N,N,N′,N′-tetramethylphosphroamidates as shelf-stable glycosyl donors
S. Hashimoto, Y. Yanagiya, Takeshi Honda, H. Harada +1 more
199237 citations
Semantic Scholar
An extremely mild and general method for the stereocontrolled construction of 1,2-cis-glycosidic linkages via S-glycopyranosyl phosphorodiamidimidothioates
Hashimoto Shunichi, Takeshi Honda, S. Ikegami
199036 citations
Semantic Scholar
Total Synthesis of Bleomycin A2 and Related Agents. 3. Synthesis and Comparative Evaluation of Deglycobleomycin A2,Epideglycobleomycin A2, Deglycobleomycin A1, and Desacetamido-, Descarboxamido-, Desmethyl-, and Desimidazolyldeglycobleomycin A2
D. Boger, Takeshi Honda, Royce F. Menezes, S. Colletti
199435 citations
Semantic Scholar
A new and general glycosidation method for podophyllum lignan glycosides
S. Hashimoto, Takeshi Honda, S. Ikegami
199135 citations
Semantic Scholar
Discovery of DS-1558: A Potent and Orally Bioavailable GPR40 Agonist.
R. Takano, Masao Yoshida, M. Inoue, Takeshi Honda +9 more
2015ACS Medicinal Chemistry Letters33 citations Open access
Semantic Scholar
A Stereocontrolled Construction of 2-Deoxy-β-glycosidic Linkages via 1,2-trans-β-Glycosidation of 2-Deoxy-2-[(p-methoxyphenyl)thio] glycopyranosyl N,N,N′,N′-Tetramethylphosphoroamidates
S. Hashimoto, Y. Yanagiya, Takeshi Honda, S. Ikegami
199227 citations
Semantic Scholar
Caseinpbospbopeptides (CPP) in Feces of Rats Fed Casein Diet.
Takanori Kasal, Takeshi Honda, S. Kiriyama
1992Bioscience, biotechnology and biochemistry27 citations Open access
Semantic Scholar
Total Synthesis of (−)-Pyrimidoblamic Acid and Deglycobleomycin A2†
D. Boger, Royce F. Menezes, Takeshi Honda
199326 citations
Semantic Scholar
Chiral synthesis of isocarbacyclin ((+)-9(0)-methano-Δ6(9α)-PGI1) intermediate via rhodium(II)-catalyzed intramolecular CH insertion reaction
S. Hashimoto, T. Shinoda, Y. Shimada, Takeshi Honda +1 more
198726 citations
Semantic Scholar
A Mild and Rapid 1,2-trans-Glycosidation Method via Benzoyl-protected Glycopyranosyl. P,P-Diphenyl-N-(p-toluenesulfonyl)phosphinimidates
S. Ikegami, S. Hashimoto, Takeshi Honda
199023 citations Open access
Semantic Scholar
Generation of efficient mutants of endoglycosidase from Streptococcus pyogenes and their application in a novel one-pot transglycosylation reaction for antibody modification
Mitsuhiro Iwamoto, Y. Sekiguchi, Kensuke Nakamura, Y. Kawaguchi +2 more
2018PLoS ONE21 citations Open access
Semantic Scholar
Discovery of 3-aryl-3-ethoxypropanoic acids as orally active GPR40 agonists.
R. Takano, Masao Yoshida, M. Inoue, Takeshi Honda +6 more
2014Bioorganic & Medicinal Chemistry Letters21 citations Open access
Semantic Scholar
Oligosaccharide synthesis based on glycosyl donors and acceptors carrying phosphorus-containing leaving groups
S. Hashimoto, H. Sakamoto, Takeshi Honda, S. Ikegami
199721 citations
Semantic Scholar
Millimeter- and Submillimeter-Wave Spectra of CuF and AgF in the X1Σ+ Electronic Ground States
T. Okabayashi, E. Yamazaki, Takeshi Honda, M. Tanimoto
200120 citations
Semantic Scholar
AN EFFICIENT CONSTRUCTION OF 1, 2-TRANS-β-GLYCOSIDIC LINKAGES VIA BENZYL-PROTECTED GLYCOPYRANOSYL P, P-DIPHENYL-N-(p-TOLUENESULFONYL)-PHOSPHINIMIDATES
S. Hashimoto, Takeshi Honda, S. Ikegami
199019 citations Open access
Semantic Scholar
Substituents at the naphthalene C3 position of (-)-Cercosporamide derivatives significantly affect the maximal efficacy as PPARγ partial agonists.
A. Furukawa, Tsuyoshi Arita, T. Fukuzaki, Susumu Satoh +7 more
2012Bioorganic & Medicinal Chemistry Letters17 citations Open access
Semantic Scholar
Synthesis and biological evaluation of novel (-)-Cercosporamide derivatives as potent selective PPARγ modulators.
A. Furukawa, Tsuyoshi Arita, T. Fukuzaki, M. Mori +12 more
2012European journal of medicinal chemistry16 citations Open access
Semantic Scholar
Synthesis of Sordaricin analogues as potent antifungal agents against Candida albicans.
S. Kaneko, T. Uchida, S. Shibuya, Takeshi Honda +4 more
2002Bioorganic & Medicinal Chemistry Letters16 citations
Semantic Scholar
Optimization of 3-aryl-3-ethoxypropanoic acids and discovery of the potent GPR40 agonist DS-1558.
R. Takano, Masao Yoshida, M. Inoue, Takeshi Honda +8 more
2015Bioorganic & Medicinal Chemistry15 citations Open access
Semantic Scholar
Potentiation of insulin secretion and improvement of glucose intolerance by combining a novel G protein-coupled receptor 40 agonist DS-1558 with glucagon-like peptide-1 receptor agonists.
Ryutaro Nakashima, Tatsuya Yano, Junko Ogawa, Naomi Tanaka +7 more
2014European Journal of Pharmacology15 citations
Semantic Scholar
Monoclonal Antibodies as Tailor-Made Hosts for Porphyrins
A. Harada, Kazutake Okamoto, M. Kamachi, Takeshi Honda +1 more
199015 citations
Semantic Scholar
Synthesis and Evaluation of the Fully Functionalized Bleomycin A2 Metal Binding Domain Containing the 2-O-(3-O-Carbamoyl-.alpha.-D-mannopyranosyl)-.alpha.-L-gulopyranosyl Disaccharide
D. Boger, S. Teramoto, Takeshi Honda, Jia-Cheng Zhou
199514 citations
Semantic Scholar
Pharmacokinetic and Pharmacodynamic Profiles of Glyco-Modified Atrial Natriuretic Peptide Derivatives Synthesized Using Chemo-enzymatic Synthesis Approaches.
Mitsuhiro Iwamoto, Takahiro Yamaguchi, Y. Sekiguchi, Shohei Oishi +10 more
2018Bioconjugate chemistry7 citations Open access
Semantic Scholar
Totalsynthese von (‐)‐Pyrimidoblamsäure und Deglycobleomycin A2
Dale L. Boger, Royce F. Menezes, Takeshi Honda
19937 citations
Semantic Scholar
Studies on the synthesis of bleomycin A2 : observations on a diastereoselective imine addition reaction for C2-acetamido side chain introduction
D. Boger, Takeshi Honda
19937 citations
Semantic Scholar
Total Synthesis of Bleomycin A2 and Related Agents. Part 4. Synthesis of the Disaccharide Subunit: 2-O-(3-O-Carbamoyl-α-D- mannopyranosyl)-L-gulopyranose and Completion of the Total Synthesis of Bleomycin A2.
D. Boger, Takeshi Honda
19945 citations
Semantic Scholar
Highly Selective Glycosidation Reactions Capitalizing on Phosphorus-containing Leaving Groups
S. Hashimoto, Takeshi Honda, Y. Yanagiya, M. Nakajima +1 more
19954 citations Open access
Semantic Scholar
Synthesis and Antiinfluenza Evaluation of Orally Active Bicyclic Ether Derivatives Related to Zanamivir.
T. Masuda, S. Shibuya, Masami Arai, Shuku Yoshida +4 more
20033 citations
Semantic Scholar
AN EFFICIENT SYNTHESIS OF (35,5S)-5-[3,3-DIMETHYL-1-(ο-TOLYL)-6-OXO-2H-PYRIDIN-4-YL]-PIPERIDINE-3-CARBOXAMIDE AS POTENT RENIN INHIBITOR
Y. Mori, Mitsuhiro Iwamoto, Kazuki Mori, Masao Yoshida +3 more
20141 citations Open access
Semantic Scholar
Synthesis of 4-guanidino-7-modified-Neu5Ac2en derivatives and their biological activities as influenza sialidase inhibitors
Takeshi Honda, M. Yamashita, T. Masuda, Shuku Yoshida +6 more
20091 citations Open access
Semantic Scholar
Oligosaccharide Synthesis Based on Glycosyl Donors and Acceptors Carrying Phosphorus-Containing Leaving Groups.
S. Hashimoto, H. Sakamoto, Takeshi Honda, S. Ikegami
19971 citations
Semantic Scholar
Total Synthesis of Bleomycin A2 and Related Agents. Part 2. Synthesis of (‐)‐Pyrimidoblamic Acid (VI), epi‐(+)‐Pyrimidoblamic Acid (VII), (+) ‐Desacetamidopyrimidoblamic Acid (V), and (‐)‐ Descarboxamidopyrimidoblamic Acid (VIII).
D. Boger, Takeshi Honda, Q. Dang
19941 citations
Semantic Scholar
Total Synthesis of Bleomycin A2 and Related Agents. Part 3. Synthesis and Comparative Evaluation of Deglycobleomycin A2, Epideglycobleomycin A2, Deglycobleomycin A1, and Desacetamido‐, Descarboxamido‐, Desmethyl‐ , and Desimidazolyldeglycobleomycin A2.
D. Boger, Takeshi Honda, Royce F. Menezes, S. Colletti
19941 citations
Semantic Scholar
A Stereocontrolled Construction of 2-Deoxy-β-glycosidic Linkages via 1,2-trans-β-Glycosidation of 2-Deoxy-2-((p-methoxyphenyl)thio) glycopyranosyl N,N,N′,N′-Tetramethylphosphoramidates.
S. Hashimoto, Y. Yanagiya, Takeshi Honda, S. Ikegami
19931 citations
Semantic Scholar
An Efficient Construction of 1,2-trans-β-Glycosidic Linkages via Benzyl-Protected Glycopyranosyl P,P-Diphenyl-N-(p-toluenesulfonyl) phosphinimidates.
S. Hashimoto, Takeshi Honda, S. Ikegami
19911 citations
Semantic Scholar
A Rapid and Efficient Synthesis of 1,2-trans-β-Linked Glycosides via Benzyl- or Benzoyl-Protected Glycopyranosyl Phosphates.
S. Hashimoto, Takeshi Honda, S. Ikegami
19891 citations
Semantic Scholar
トラスツズマブ・デルクステカン(DS-8201a),トポイソメラーゼI阻害剤エクサテカン誘導体ベースのHER2標的化抗体-薬物抱合体のプロファイル
T. Nakada, H. Naito, Ogitani Yusuke, Jikoh Takahiro +12 more
20180 citations
Semantic Scholar

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