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N. Smart · SciRah

Researcher profile · Semantic Scholar

N. Smart

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N. Smart — researcher profile on SciRah

h-index: 33
Works: 96
Citations: 4,331

Most-cited papers

Thymosin β4 induces adult epicardial progenitor mobilization and neovascularization
N. Smart, Catherine A. Risebro, Athalie A. D. Melville, Kelvin A. Moses +3 more
2007Nature664 citations
Semantic Scholar
De novo cardiomyocytes from within the activated adult heart after injury
N. Smart, S. Bollini, K. Dubé, J. Vieira +8 more
2011Nature650 citations Open access
Semantic Scholar
Fraser syndrome and mouse blebbed phenotype caused by mutations in FRAS1/Fras1 encoding a putative extracellular matrix protein
L. McGregor, V. Makela, S. Darling, S. Vrontou +21 more
2003Nature Genetics256 citations
Semantic Scholar
The Stem Cell Movement
N. Smart, P. Riley
2008Circulation Research184 citations Open access
Semantic Scholar
Resident cardiac progenitor cells: at the heart of regeneration.
S. Bollini, N. Smart, P. Riley
2011Journal of Molecular and Cellular Cardiology178 citations
Semantic Scholar
IL-6 induces PI 3-kinase and nitric oxide-dependent protection and preserves mitochondrial function in cardiomyocytes.
N. Smart, M. Mojet, D. Latchman, M. Marber +2 more
2006Cardiovascular Research142 citations Open access
Semantic Scholar
Amniotic Fluid Stem Cells Are Cardioprotective Following Acute Myocardial Infarction
S. Bollini, K. Cheung, J. Riegler, Xuebin Dong +8 more
2011Stem Cells and Development113 citations
Semantic Scholar
Human CD68 promoter GFP transgenic mice allow analysis of monocyte to macrophage differentiation in vivo.
A. Iqbal, E. McNeill, T. S. Kapellos, Daniel Regan-Komito +9 more
2014Blood101 citations Open access
Semantic Scholar
Thymosin β4 facilitates epicardial neovascularization of the injured adult heart
N. Smart, Catherine A. Risebro, James E. Clark, E. Ehler +4 more
2010Annals of the New York Academy of Sciences96 citations
Semantic Scholar
p42/p44-MAPK and PI3K are sufficient for IL-6 family cytokines/gp130 to signal to hypertrophy and survival in cardiomyocytes in the absence of JAK/STAT activation
Ahmed Fahmi, N. Smart, A. Punn, R. Jabr +2 more
2013Cellular Signalling94 citations Open access
Semantic Scholar
Nucleolar release of Hand1 acts as a molecular switch to determine cell fate
D. Martindill, Catherine A. Risebro, N. Smart, Maria Del Mar Franco-Viseras +4 more
2007Nature Cell Biology91 citations
Semantic Scholar
Re-Activated Adult Epicardial Progenitor Cells Are a Heterogeneous Population Molecularly Distinct from Their Embryonic Counterparts
S. Bollini, J. Vieira, S. Howard, K. Dubé +3 more
2014Stem Cells and Development86 citations
Semantic Scholar
Hand1 regulates cardiomyocyte proliferation versus differentiation in the developing heart
Catherine A. Risebro, N. Smart, L. Dupays, R. Breckenridge +2 more
2006Development81 citations Open access
Semantic Scholar
Thymosin β4-sulfoxide attenuates inflammatory cell infiltration and promotes cardiac wound healing
M. Evans, N. Smart, K. Dubé, S. Bollini +11 more
2013Nature Communications80 citations Open access
Semantic Scholar
Thymosin β4 and angiogenesis: modes of action and therapeutic potential
N. Smart, A. Rossdeutsch, P. Riley
2007Angiogenesis76 citations
Semantic Scholar
Recapitulation of developmental mechanisms to revascularize the ischemic heart
K. Dubé, Tonia M. Thomas, Sonali Munshaw, M. Rohling +2 more
2017JCI Insight73 citations Open access
Semantic Scholar
Thymosins in Health and Disease: 2nd International Symposium
N. Smart, Catherine A. Risebro, James E. Clark, E. Ehler +4 more
201070 citations
Semantic Scholar
Vascularizing the heart.
P. Riley, N. Smart
2011Cardiovascular Research68 citations Open access
Semantic Scholar
Spatiotemporal Analysis Reveals Overlap of Key Proepicardial Markers in the Developing Murine Heart
Irina-Elena Lupu, A. Redpath, N. Smart
2020Stem Cell Reports64 citations Open access
Semantic Scholar
The epicardium as a candidate for heart regeneration
N. Smart, P. Riley
2012Future Cardiology63 citations Open access
Semantic Scholar
Coronary vessel formation in development and disease: mechanisms and insights for therapy
Irina-Elena Lupu, S. De Val, N. Smart
2020Nature Reviews Cardiology60 citations Open access
Semantic Scholar
Epicardial progenitor cells in cardiac regeneration and neovascularisation.
N. Smart, K. Dubé, P. Riley
2013Vascular pharmacology59 citations
Semantic Scholar
Essential Role for Thymosin &bgr;4 in Regulating Vascular Smooth Muscle Cell Development and Vessel Wall Stability
A. Rossdeutsch, N. Smart, K. Dubé, M. Turner +1 more
2012Circulation Research59 citations Open access
Semantic Scholar
Genetic Targeting of Organ-Specific Blood Vessels
Wen-Juan Pu, Lingjuan He, Xi-Meng Han, Xueying Tian +10 more
2018Circulation Research56 citations Open access
Semantic Scholar
Coronary vessel development and insight towards neovascular therapy
N. Smart, K. Dubé, Paul R. Riley
2009International journal of experimental pathology (Print)56 citations Open access
Semantic Scholar
Mapping the developing human cardiac endothelium at single-cell resolution identifies MECOM as a regulator of arteriovenous gene expression
I. McCracken, R. Dobie, M. Bennett, Rainha Passi +8 more
2022Cardiovascular Research55 citations Open access
Semantic Scholar
Thymosin β‐4 Is Essential for Coronary Vessel Development and Promotes Neovascularization via Adult Epicardium
N. Smart, Catherine A. Risebro, Athalie A. D. Melville, Kelvin A. Moses +3 more
2007Annals of the New York Academy of Sciences54 citations
Semantic Scholar
Immunomodulation for optimal cardiac regeneration: insights from comparative analyses
Luiza Farache Trajano, N. Smart
2021npj Regenerative Medicine43 citations Open access
Semantic Scholar
Epistatic Rescue of Nkx2.5 Adult Cardiac Conduction Disease Phenotypes by Prospero-Related Homeobox Protein 1 and HDAC3
Catherine A. Risebro, L. Petchey, N. Smart, J. Gomes +13 more
2012Circulation Research43 citations Open access
Semantic Scholar
Identification of Thymosin β4 as an effector of Hand1-mediated vascular development
N. Smart, K. Dubé, P. Riley
2010Nature Communications43 citations Open access
Semantic Scholar
Thymosin beta4 and angiogenesis: modes of action and therapeutic potential.
N. Smart, A. Rossdeutsch, P. Riley
2007Angiogenesis39 citations
Semantic Scholar
Myocardial Regeneration: Expanding the Repertoire of Thymosin β4 in the Ischaemic Heart
N. Smart, S. Bollini, K. Dubé, J. M. Vieira +8 more
2012Annals of the New York Academy of Sciences37 citations Open access
Semantic Scholar
Thymosin β4: multiple functions in protection, repair and regeneration of the mammalian heart
S. Bollini, P. Riley, N. Smart
2015Expert Opinion on Biological Therapy36 citations
Semantic Scholar
Apj+ Vessels Drive Tumor Growth and Represent a Tractable Therapeutic Target.
Huan Zhao, Xueying Tian, Lingjuan He, Yan Li +12 more
2022Cell Reports31 citations Open access
Semantic Scholar
Derivation of epicardium-derived progenitor cells (EPDCs) from adult epicardium.
N. Smart, P. Riley
2009Current protocols in stem cell biology31 citations
Semantic Scholar
Thymosin beta 4 is essential for coronary vessel development and promotes neovascularisation via adult epicardium
N. Smart, Catherine A. Risebro, Athalie A. D. Melville, Kelvin A. Moses +3 more
200730 citations
Semantic Scholar
Thymosin β4 protects against aortic aneurysm via endocytic regulation of growth factor signaling
Sonali Munshaw, S. Bruche, A. Redpath, Alisha N. Jones +11 more
2021Journal of Clinical Investigation29 citations Open access
Semantic Scholar
Insights into therapeutic products, preclinical research models and clinical trials in cardiac regenerative and reparative medicine: where are we now and the way ahead. Current opinion paper of the ESC working group on cardiovascular regenerative and reparative medicine.
Shamagian L Grigorian, R. Sanz-Ruiz, A. Climent, L. Badimón +16 more
2020Cardiovascular Research27 citations Open access
Semantic Scholar
Thymosin beta4 induces epicardium-derived neovascularization in the adult heart.
P. Riley, N. Smart
2009Biochemical Society Transactions27 citations
Semantic Scholar
A differential screen for putative targets of the bHLH transcription factor Hand1 in cardiac morphogenesis.
N. Smart, Alison A. Hill, J. Cross, P. Riley
2002Gene Expression Patterns26 citations
Semantic Scholar
Extension of Endocardium-Derived Vessels Generate Coronary Arteries in Neonates
Juan Tang, Huan Zhu, Xueying Tian, Haixiao Wang +13 more
2022Circulation Research24 citations Open access
Semantic Scholar
Regulatory pathways governing murine coronary vessel formation are dysregulated in the injured adult heart
S. Payne, M. Gunadasa-Rohling, A. Neal, A. Redpath +5 more
2019Nature Communications23 citations Open access
Semantic Scholar
A rapid and sensitive assay for quantification of siRNA efficiency and specificity
N. Smart, P. Scambler, P. Riley
2005Biological Procedures Online23 citations Open access
Semantic Scholar
Thymosin β4 and the vasculature: multiple roles in development, repair and protection against disease
K. Dubé, N. Smart
2018Expert Opinion on Biological Therapy20 citations Open access
Semantic Scholar
Recapturing embryonic potential in the adult epicardium: Prospects for cardiac repair
A. Redpath, N. Smart
2020Stem Cells Translational Medicine17 citations Open access
Semantic Scholar
Thymosin β4 protein therapy for cardiac repair.
K. Dubé, S. Bollini, N. Smart, P. Riley
2012Current pharmaceutical design17 citations
Semantic Scholar
Prospects for improving neovascularization of the ischemic heart: Lessons from development
N. Smart
2017Microcirculation16 citations
Semantic Scholar
Thymosin beta4 and Ac-SDKP: tools to mend a broken heart.
A. Rossdeutsch, N. Smart, P. Riley
2008Journal of molecular medicine15 citations
Semantic Scholar
Aberrant developmental titin splicing and dysregulated sarcomere length in Thymosin β4 knockout mice
N. Smart, J. Riegler, Cameron W. Turtle, C. Lygate +9 more
2017Journal of Molecular and Cellular Cardiology14 citations Open access
Semantic Scholar
Thymosin β4 in Vascular Development
N. Smart, P. Riley
2013Circulation Research14 citations Open access
Semantic Scholar

Frequent co-authors

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P. Riley×31
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P. Riley — researcher profile on SciRah
K. Dubé×14
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K. Dubé — researcher profile on SciRah
S. Bollini×8
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S. Bollini — researcher profile on SciRah
Catherine A. Risebro×6
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Catherine A. Risebro — researcher profile on SciRah

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A. Rossdeutsch — researcher profile on SciRah

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J. Riegler — researcher profile on SciRah

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M. Lythgoe — researcher profile on SciRah

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R. Schwartz — researcher profile on SciRah

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A. Price — researcher profile on SciRah

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A. Redpath — researcher profile on SciRah

Athalie A. D. Melville×3

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Athalie A. D. Melville — researcher profile on SciRah

Kelvin A. Moses×3

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Kelvin A. Moses — researcher profile on SciRah