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D. Latchman · SciRah

Researcher profile · Semantic Scholar

D. Latchman

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D. Latchman — researcher profile on SciRah

h-index: 88
Works: 668
Citations: 31K

Most-cited papers

PINK1-Associated Parkinson's Disease Is Caused by Neuronal Vulnerability to Calcium-Induced Cell Death
S. Gandhi, A. Wood‐Kaczmar, Z. Yao, H. Plun-Favreau +8 more
2009Molecules and Cells684 citations Open access
Semantic Scholar
PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons
A. Wood‐Kaczmar, S. Gandhi, Z. Yao, A. Abramov +15 more
2008PLoS ONE332 citations Open access
Semantic Scholar
Dysregulation of Histone Acetylation in the APP/PS1 Mouse Model of Alzheimer’s Disease
Yitshak I. Francis, M. Fa', Haider Ashraf, Hong Zhang +3 more
2009Journal of Alzheimer's Disease285 citations Open access
Semantic Scholar
In vivo inhibition of antiphospholipid antibody‐induced pathogenicity utilizing the antigenic target peptide domain I of β2‐glycoprotein I: proof of concept
Y. Ioannou, Z. Romay-Penabad, C. Pericleous, I. Giles +7 more
2009Journal of Thrombosis and Haemostasis133 citations Open access
Semantic Scholar
Protective effects of heat shock protein 27 in a model of ALS occur in the early stages of disease progression.
P. Sharp, M. Akbar, S. Bouri, A. Senda +5 more
2008Neurobiology of Disease117 citations Open access
Semantic Scholar
Antibodies to apolipoprotein A-I, high-density lipoprotein, and C-reactive protein are associated with disease activity in patients with systemic lupus erythematosus.
S. O'Neill, I. Giles, A. Lambrianides, J. Manson +6 more
2010Arthritis & Rheumatism113 citations
Semantic Scholar
STAT3 modulates the DNA damage response pathway
Seán P. Barry, P. Townsend, R. Knight, T. Scarabelli +2 more
2010International journal of experimental pathology (Print)108 citations Open access
Semantic Scholar
Targeting STAT1 by myricetin and delphinidin provides efficient protection of the heart from ischemia/reperfusion‐induced injury
T. Scarabelli, S. Mariotto, S. Abdel-Azeim, K. Shoji +15 more
2009FEBS Letters95 citations Open access
Semantic Scholar
Effects of polyclonal IgG derived from patients with different clinical types of the antiphospholipid syndrome on monocyte signalling pathways
A. Lambrianides, C. Carroll, S. Pierangeli, C. Pericleous +7 more
2010Journal of Immunology86 citations Open access
Semantic Scholar
STAT1 interacts directly with cyclin D1/Cdk4 and mediates cell cycle arrest
Gloria Dimco, R. Knight, D. Latchman, A. Stephanou
2010Cell Cycle82 citations Open access
Semantic Scholar
Transcriptional Modulation of Heat-Shock Protein Gene Expression
A. Stephanou, D. Latchman
2010Biochemistry Research International78 citations Open access
Semantic Scholar
Molecular basis of Parkinson's disease.
Yan-Xiang Yang, N. Wood, D. Latchman
2009NeuroReport78 citations
Semantic Scholar
STAT3 deletion sensitizes cells to oxidative stress
Seán P. Barry, P. Townsend, J. McCormick, R. Knight +3 more
2009Biochemical and Biophysical Research Communications - BBRC61 citations Open access
Semantic Scholar
Overexpression of Heat Shock Protein 27 Reduces Cortical Damage after Cerebral Ischemia
L. van der Weerd, Mohammed Tariq Akbar, Romina Aron Badin, L. Valentim +6 more
2010Journal of Cerebral Blood Flow and Metabolism53 citations Open access
Semantic Scholar
Enhanced IL-17 signalling following myocardial ischaemia/reperfusion injury
Seán P. Barry, S. Ounzain, J. McCormick, T. Scarabelli +9 more
2013International Journal of Cardiology52 citations Open access
Semantic Scholar
Estrogen and non‐genomic upregulation of voltage‐gated Na+ channel activity in MDA‐MB‐231 human breast cancer cells: Role in adhesion
S. P. Fraser, Iley Ozerlat-Gunduz, Rustem Onkal, J. Diss +2 more
2010Journal of Cellular Physiology49 citations
Semantic Scholar
ERK and the F-box Protein βTRCP Target STAT1 for Degradation*
S. Soond, P. Townsend, Seán P. Barry, R. Knight +2 more
2008Journal of Biological Chemistry49 citations Open access
Semantic Scholar
Nurr1 transcriptionally regulates the expression of &agr;-synuclein
Yan-Xiang Yang, D. Latchman
2008NeuroReport46 citations
Semantic Scholar
Characterisation of a novel NR4A2 mutation in Parkinson’s disease brain
P. Sleiman, D. Healy, M. Muqit, Yan-Xiang Yang +10 more
2009Neuroscience Letters45 citations Open access
Semantic Scholar
New targets of urocortin-mediated cardioprotection
Seán P. Barry, K. Lawrence, J. McCormick, S. Soond +9 more
2010Journal of Molecular Endocrinology42 citations Open access
Semantic Scholar
Signal transducer and activator of transcription-1 localizes to the mitochondria and modulates mitophagy
L. Bourke, R. Knight, D. Latchman, A. Stephanou +1 more
2013JAK-STAT39 citations Open access
Semantic Scholar
Identification and characterization of the promoter region of the Nav1.7 voltage-gated sodium channel gene (SCN9A)
J. Diss, M. Calissano, D. Gascoyne, M. Djamgoz +1 more
2008Molecular and Cellular Neuroscience35 citations
Semantic Scholar
Endothelial microparticle release is stimulated in vitro by purified IgG from patients with the antiphospholipid syndrome
C. Pericleous, L. Clarke, P. Brogan, D. Latchman +4 more
2012Thrombosis and Haemostasis26 citations
Semantic Scholar
p73-mediated transcriptional activity is negatively regulated by Polo-like kinase 1
S. Soond, Seán P. Barry, G. Melino, R. Knight +2 more
2008Cell Cycle26 citations Open access
Semantic Scholar
Thrombin Binding Predicts the Effects of Sequence Changes in a Human Monoclonal Antiphospholipid Antibody on Its In Vivo Biologic Actions 1
I. Giles, C. Pericleous, Xiaowei Liu, J. Ehsanullah +10 more
2009Journal of Immunology24 citations Open access
Semantic Scholar
Anti-factor Xa antibodies in patients with antiphospholipid syndrome and their effects upon coagulation assays
B. Artım-Esen, C. Pericleous, I. Mackie, V. Ripoll +5 more
2015Arthritis Research & Therapy23 citations Open access
Semantic Scholar
Retracted: Cardiac release of urocortin precedes the occurrence of irreversible myocardial damage in the rat heart exposed to ischemia/reperfusion injury
Richard A. Knight, C. Chen-Scarabelli, Zhaokan Yuan, R. Mccauley +10 more
2008FEBS Letters23 citations Open access
Semantic Scholar
Proliferation-associated Brn-3b transcription factor can activate cyclin D1 expression in neuroblastoma and breast cancer cells
V. Budhram-Mahadeo, S. Irshad, S. Bowen, S. -. Lee +3 more
2008Oncogene23 citations Open access
Semantic Scholar
Protective effect of post-ischaemic viral delivery of heat shock proteins in vivo
R. A. Badin, M. Modo, M. Cheetham, David L. Thomas +3 more
2008Journal of Cerebral Blood Flow and Metabolism22 citations Open access
Semantic Scholar
Bio-electrospraying primary cardiac cells: in vitro tissue creation and functional study.
K. Ng, Pascal Joly, S. Jayasinghe, Bertrand Vernay +5 more
2011Biotechnology Journal21 citations
Semantic Scholar
Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons
A. Wood‐Kaczmar, S. Gandhi, Z. Yao, A. Abramov +15 more
2008PLoS ONE21 citations Open access
Semantic Scholar
Changes in regulation of human monocyte proteins in response to IgG from patients with antiphospholipid syndrome.
V. Ripoll, A. Lambrianides, S. Pierangeli, K. Poulton +7 more
2014Blood20 citations Open access
Semantic Scholar
The role of minocycline in ischemia-reperfusion injury: a comprehensive review of an old drug with new implications.
Berkin O. Ulgen, Matthew G. Field, W. Qureshi, R. Knight +11 more
2011Recent Advances in Cardiovascular Drug Discovery (Formerly Recent Patents on Cardiovascular Drug Discovery)19 citations
Semantic Scholar
Correction: PINK1 Is Necessary for Long Term Survival and Mitochondrial Function in Human Dopaminergic Neurons
A. Wood‐Kaczmar, S. Gandhi, Z. Yao, A. Abramov +15 more
2008PLoS ONE19 citations Open access
Semantic Scholar
Autophagy in the stress-induced myocardium.
J. McCormick, R. Knight, Seán P. Barry, T. Scarabelli +3 more
2012Frontiers in Bioscience18 citations Open access
Semantic Scholar
Evaluating the conformation of recombinant domain I of β2-glycoprotein I and its interaction with human monoclonal antibodies
C. Pericleous, J. Miles, D. Esposito, A. Garza-Garcia +7 more
2011Molecular Immunology18 citations Open access
Semantic Scholar
Green tea polyphenol epigallocatechin gallate inhibits cell signaling by inducing SOCS1 gene expression.
B. Ripley, M. Fujimoto, S. Serada, T. Ohkawara +9 more
2010International Immunology16 citations Open access
Semantic Scholar
Regulation of Brn-3a N-terminal transcriptional activity by MEK1/2-ERK1/2 signalling in neural differentiation.
D. Berwick, M. Calissano, J. Corness, S. Cook +1 more
2009Brain Research16 citations
Semantic Scholar
Gene expression studies on bio‐electrosprayed primary cardiac myocytes
Seán P. Barry, S. Jayasinghe, C. Pericleous, M. Hubank +2 more
2008Biotechnology Journal16 citations
Semantic Scholar
Brn-3a transcription factor blocks p53-mediated activation of proapoptotic target genes Noxa and Bax in vitro and in vivo to determine cell fate.
C. Hudson, P. Morris, D. Latchman, V. Budhram-Mahadeo
2015Journal of Biological Chemistry15 citations Open access
Semantic Scholar
The cardioprotective effects of urocortin are mediated via activation of the Src tyrosine kinase-STAT3 pathway
C. Chen-Scarabelli, L. Saravolatz, Roy Mccaukey, G. Scarabelli +11 more
2013JAK-STAT15 citations Open access
Semantic Scholar
Interactions of human monoclonal and polyclonal antiphospholipid antibodies with serine proteases involved in hemostasis
A. Lambrianides, T. Turner-Stokes, C. Pericleous, J. Ehsanullah +10 more
2011Arthritis & Rheumatism15 citations Open access
Semantic Scholar
Regulation of Myocardial Interleukin-6 Expression by p53 and STAT1
C. Carroll, B. S. Sayan, Sarah G. Bailey, J. McCormick +3 more
2013Journal of Interferon and Cytokine Research14 citations Open access
Semantic Scholar
Cardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expression
Saleha R. Farooqui-Kabir, J. Diss, D. Henderson, M. Marber +3 more
2008Cell stress & chaperones (Print)14 citations Open access
Semantic Scholar
Amino acid supplementation differentially modulates STAT1 and STAT3 activation in the myocardium exposed to ischemia/reperfusion injury.
T. Scarabelli, P. Townsend, C. Chen-Scarabelli, Zhaokan Yuan +12 more
2008American Journal of Cardiology13 citations
Semantic Scholar
Gene Control
D. Latchman
2020Structure and Function of the Bacterial Genome10 citations
Semantic Scholar
Cell-specific regulation of the pro-survival Brn-3b transcription factor by microRNAs.
M. Calissano, D. Latchman
2010Molecular and cellular neurosciences10 citations
Semantic Scholar
A Simple Technique for the Prediction of Interacting Proteins Reveals a Direct Brn-3a-Androgen Receptor Interaction*
D. Berwick, J. Diss, V. Budhram-Mahadeo, D. Latchman
2010Journal of Biological Chemistry10 citations Open access
Semantic Scholar
Brn-3a/POU4F1 interacts with and differentially affects p73-mediated transcription
C. Hudson, A. Sayan, G. Melino, R. Knight +2 more
2008Cell Death and Differentiation9 citations Open access
Semantic Scholar
Conclusions and Future Prospects
D. Latchman
2020Gene Control7 citations
Semantic Scholar

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A. Stephanou×19
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A. Stephanou — researcher profile on SciRah
R. Knight×16
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R. Knight — researcher profile on SciRah
Seán P. Barry×11
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Seán P. Barry — researcher profile on SciRah
D. Isenberg×10
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T. Scarabelli — researcher profile on SciRah

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I. Giles — researcher profile on SciRah

C. Pericleous×8

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Anisur Rahman×8

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Anisur Rahman — researcher profile on SciRah

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P. Townsend — researcher profile on SciRah

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Y. Ioannou — researcher profile on SciRah

A. Lambrianides×6

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A. Lambrianides — researcher profile on SciRah