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A. Adler · SciRah

Researcher profile · Semantic Scholar

A. Adler

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A. Adler — researcher profile on SciRah

h-index: 40
Works: 110
Citations: 6,027

Most-cited papers

Variants at multiple loci implicated in both innate and adaptive immune responses are associated with Sjögren’s syndrome
C. Lessard, He Li, I. Adrianto, J. Ice +56 more
2013Nature Genetics525 citations Open access
Semantic Scholar
CD4+ T Cell Tolerance to Parenchymal Self-Antigens Requires Presentation by Bone Marrow–derived Antigen-presenting Cells
A. Adler, David W. Marsh, G. Yochum, James L. Guzzo +3 more
1998Journal of Experimental Medicine324 citations Open access
Semantic Scholar
Macrophage polarization and Metainflammation
Chuan Li, Maria M. Xu, Ke-Peng Wang, A. Adler +2 more
2017Translational Research: The Journal of Laboratory and Clinical Medicine317 citations Open access
Semantic Scholar
Safety and feasibility of injection with an E1B-55 kDa gene-deleted, replication-selective adenovirus (ONYX-015) into primary carcinomas of the pancreas: a phase I trial
S. Mulvihill, R. Warren, A. Venook, A. Adler +3 more
2001Gene Therapy306 citations Open access
Semantic Scholar
Androgen ablation mitigates tolerance to a prostate/prostate cancer-restricted antigen.
C. Drake, Amy D. H. Doody, M. Mihalyo, Ching-Tai Huang +11 more
2005Cancer Cell301 citations Open access
Semantic Scholar
Evaluation of the TREX1 gene in a large multi-ancestral lupus cohort
B. Namjou, P. Kothari, J. Kelly, S. Glenn +36 more
2011Genes and Immunity262 citations Open access
Semantic Scholar
Lymphatic endothelial cells induce tolerance via PD-L1 and lack of costimulation leading to high-level PD-1 expression on CD8 T cells.
E. Tewalt, Jarish N. Cohen, S. Rouhani, Cynthia J. Guidi +9 more
2012Blood261 citations Open access
Semantic Scholar
High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
Ce-Li Sun, J. Molineros, L. Looger, Xu-Jie Zhou +34 more
2016Nature Genetics253 citations Open access
Semantic Scholar
Association of Genetic Variants in Complement Factor H and Factor H-Related Genes with Systemic Lupus Erythematosus Susceptibility
Jian Zhao, Hui Wu, M. Khosravi, Hui-Juan Cui +51 more
2011PLoS Genetics221 citations Open access
Semantic Scholar
Tc17 CD8 T Cells: Functional Plasticity and Subset Diversity
Hung-Rong Yen, T. Harris, S. Wada, J. Grosso +13 more
2009Journal of Immunology210 citations Open access
Semantic Scholar
Identification of IRF8, TMEM39A, and IKZF3-ZPBP2 as susceptibility loci for systemic lupus erythematosus in a large-scale multiracial replication study.
C. Lessard, I. Adrianto, J. Ice, G. Wiley +54 more
2012American Journal of Human Genetics177 citations Open access
Semantic Scholar
CD134 Plus CD137 Dual Costimulation Induces Eomesodermin in CD4 T Cells to Program Cytotoxic Th1 Differentiation
H. Qui, Adam T. Hagymasi, Suman Bandyopadhyay, Marie-Clare St Rose +7 more
2011Journal of Immunology162 citations Open access
Semantic Scholar
GWAS in an Amerindian ancestry population reveals novel systemic lupus erythematosus risk loci and the role of European admixture
M. Alarconriquelme, J. Ziegler, J. Molineros, Timothy D Howard +41 more
2015Arthritis & Rheumatology160 citations Open access
Semantic Scholar
Glycoprotein 96 Can Chaperone Both MHC Class I- and Class II-Restricted Epitopes for In Vivo Presentation, but Selectively Primes CD8+ T Cell Effector Function 1
Amy D. H. Doody, J. Kovalchin, M. Mihalyo, Adam T. Hagymasi +2 more
2004Journal of Immunology149 citations Open access
Semantic Scholar
IL-17 inhibits CXCL9/10-mediated recruitment of CD8+ cytotoxic T cells and regulatory T cells to colorectal tumors
Ju Chen, Xiaoyang Ye, Elise Pitmon, Menglong Lu +5 more
2019Journal of Immunotherapy for Cancer119 citations Open access
Semantic Scholar
Admixture Mapping in Lupus Identifies Multiple Functional Variants within IFIH1 Associated with Apoptosis, Inflammation, and Autoantibody Production
J. Molineros, A. Maiti, Ce-Li Sun, L. Looger +33 more
2013PLoS Genetics119 citations Open access
Semantic Scholar
Genome-Wide Association Study of African and European Americans Implicates Multiple Shared and Ethnic Specific Loci in Sarcoidosis Susceptibility
I. Adrianto, C. Lin, Jessica J. Hale, A. Levin +12 more
2012PLoS ONE118 citations Open access
Semantic Scholar
Fine Mapping of Xq28: Both MECP2 and IRAK1 Contribute to Risk for Systemic Lupus Erythematosus in Multiple Ancestral Groups
K. Kaufman, Jian Zhao, J. Kelly, T. Hughes +46 more
2012Annals of the Rheumatic Diseases107 citations Open access
Semantic Scholar
In Vivo CD4+ T Cell Tolerance Induction Versus Priming Is Independent of the Rate and Number of Cell Divisions1
A. Adler, Ching-Tai Huang, G. Yochum, David W. Marsh +1 more
2000Journal of Immunology105 citations Open access
Semantic Scholar
Identification of a systemic lupus erythematosus susceptibility locus at 11p13 between PDHX and CD44 in a multiethnic study.
Christopher J. Lessard, I. Adrianto, J. Kelly, K. Kaufman +40 more
2011American Journal of Human Genetics91 citations Open access
Semantic Scholar
Impact of Genetic Ancestry and Socio-Demographic Status on the Clinical Expression of Systemic Lupus Erythematosus in Amerindian-European Populations
E. Sánchez, A. Rasmussen, L. Riba, E. Acevedo-Vásquez +50 more
2012Arthritis & Rheumatism89 citations Open access
Semantic Scholar
Addressing current challenges in cancer immunotherapy with mathematical and computational modeling
A. Konstorum, A. Vella, A. Adler, R. Laubenbacher
2017bioRxiv86 citations Open access
Semantic Scholar
CD4+ T Cells Pass Through an Effector Phase During the Process of In Vivo Tolerance Induction
Ching-Tai Huang, D. Huso, Zhenbing Lu, Tianhong Wang +8 more
2003Journal of Immunology86 citations Open access
Semantic Scholar
The IRF5-TNPO3 association with systemic lupus erythematosus has two components that other autoimmune disorders variably share.
L. Kottyan, Erin E. Zoller, J. Bene, Xiaoming Lu +78 more
2014Human Molecular Genetics81 citations Open access
Semantic Scholar
Two Independent Functional Risk Haplotypes in TNIP1 are Associated with Systemic Lupus Erythematosus
I. Adrianto, Shao-Feng Wang, G. Wiley, C. Lessard +45 more
2012Arthritis & Rheumatism77 citations Open access
Semantic Scholar
Allelic heterogeneity in NCF2 associated with systemic lupus erythematosus (SLE) susceptibility across four ethnic populations.
X. Kim-Howard, Ce-Li Sun, J. Molineros, A. Maiti +51 more
2014Human Molecular Genetics74 citations Open access
Semantic Scholar
Evidence for gene-gene epistatic interactions among susceptibility loci for systemic lupus erythematosus
T. Hughes, A. Adler, J. Kelly, K. M. Kaufman +29 more
2012Arthritis & Rheumatism64 citations Open access
Semantic Scholar
PTPN22 Association in Systemic Lupus Erythematosus (SLE) with Respect to Individual Ancestry and Clinical Sub-Phenotypes
B. Namjou, X. Kim-Howard, Ce-Li Sun, A. Adler +35 more
2013PLoS ONE63 citations Open access
Semantic Scholar
Variation in the ICAM1–ICAM4–ICAM5 locus is associated with systemic lupus erythematosus susceptibility in multiple ancestries
Kwangwoo Kim, E. Brown, Chan-Bum Choi, M. Alarconriquelme +46 more
2012Annals of the Rheumatic Diseases63 citations Open access
Semantic Scholar
Cutting Edge: Paracrine, but Not Autocrine, IL-2 Signaling Is Sustained during Early Antiviral CD4 T Cell Response1
Meixiao Long, A. Adler
2006Journal of Immunology62 citations Open access
Semantic Scholar
Two functional lupus-associated BLK promoter variants control cell-type- and developmental-stage-specific transcription.
J. Guthridge, Rufei Lu, Harry Sun, Ce-Li Sun +47 more
2014American Journal of Human Genetics61 citations Open access
Semantic Scholar
A functional haplotype of UBE2L3 confers risk for Systemic Lupus Erythematosus
Shao-Feng Wang, I. Adrianto, G. Wiley, Christopher J. Lessard +45 more
2012Genes and Immunity60 citations Open access
Semantic Scholar
Evaluation of the genetic association of the PTPN22 R620W polymorphism in familial and sporadic systemic lupus erythematosus.
K. Kaufman, J. Kelly, Betty J. Herring, A. Adler +7 more
2006Arthritis & Rheumatism53 citations
Semantic Scholar
Evaluation of TRAF6 in a Large Multi-Ancestral Lupus Cohort
B. Namjou, Chan-Bum Choi, Isaac T. W. Harley, M. Alarconriquelme +43 more
2012Arthritis & Rheumatism52 citations Open access
Semantic Scholar
CD4 Cell Priming and Tolerization Are Differentially Programmed by APCs upon Initial Engagement1
A. Higgins, M. Mihalyo, Patrick W. McGary, A. Adler
2002Journal of Immunology49 citations Open access
Semantic Scholar
Costimulation endows immunotherapeutic CD8 T cells with IL-36-responsiveness during aerobic glycolysis
N. Tsurutani, P. Mittal, Marie-Clare St Rose, S. Ngoi +8 more
2015Journal of Immunology46 citations Open access
Semantic Scholar
Effector CD4 Cells Are Tolerized Upon Exposure to Parenchymal Self-Antigen1
A. Higgins, M. Mihalyo, A. Adler
2002Journal of Immunology46 citations Open access
Semantic Scholar
Tumor Recognition and Self-Recognition Induce Distinct Transcriptional Profiles in Antigen-Specific CD4 T Cells
D. Getnet, Charles H. Maris, Edward L. Hipkiss, J. Grosso +10 more
2009Journal of Immunology41 citations Open access
Semantic Scholar
In Vivo Cyclophosphamide and IL-2 Treatment Impedes Self-Antigen-Induced Effector CD4 Cell Tolerization: Implications for Adoptive Immunotherapy1
M. Mihalyo, Amy D. H. Doody, Jeremy P. McAleer, E. Nowak +3 more
2004Journal of Immunology41 citations Open access
Semantic Scholar
Presensitizing with a Toll-like receptor 3 ligand impairs CD8 T-cell effector differentiation and IL-33 responsiveness
S. Ngoi, Marie-Clare St Rose, A. Ménoret, Dirk E. Smith +3 more
2012Proceedings of the National Academy of Sciences of the United States of America40 citations Open access
Semantic Scholar
Lupus Risk Variant Increases pSTAT1 Binding and Decreases ETS1 Expression.
Xiaoming Lu, Erin E. Zoller, M. Weirauch, Zhiguo Wu +42 more
2015American Journal of Human Genetics39 citations Open access
Semantic Scholar
Mechanisms of T cell tolerance and suppression in cancer mediated by tumor-associated antigens and hormones.
A. Adler
2007Current Cancer Drug Targets38 citations
Semantic Scholar
Lupus risk variants in the PXK locus alter B-cell receptor internalization
Samuel E. Vaughn, Corinne L Foley, Xiaoming Lu, Z. Patel +43 more
2015Frontiers in Genetics33 citations Open access
Semantic Scholar
A plausibly causal functional lupus-associated risk variant in the STAT1–STAT4 locus
Z. Patel, Xiaoming Lu, Daniel E. Miller, C. Forney +65 more
2018Human Molecular Genetics31 citations Open access
Semantic Scholar
Betting on improved cancer immunotherapy by doubling down on CD134 and CD137 co-stimulation
A. Adler, A. Vella
2013Oncoimmunology27 citations Open access
Semantic Scholar
Steady State Dendritic Cells Present Parenchymal Self-Antigen and Contribute to, but Are Not Essential for, Tolerization of Naive and Th1 Effector CD4 Cells1
Adam T. Hagymasi, A. Slaiby, M. Mihalyo, H. Qui +3 more
2007Journal of Immunology27 citations Open access
Semantic Scholar
Lymphocyte activation gene-3 regulates dendritic cell metabolic programing and T cell priming function
Dunia García Cruz, Raghavendra R. Giri, Daylin Gamiotea Turro, Jeremy L. Balsbaugh +2 more
2021Journal of Immunology24 citations Open access
Semantic Scholar
CD134/CD137 Dual Costimulation-Elicited IFN-γ Maximizes Effector T Cell Function but Limits Treg Expansion
Marie-Clare St. Rose, Roslyn A. Taylor, Suman Bandyopadhyay, H. Qui +3 more
2013Immunology and Cell Biology24 citations Open access
Semantic Scholar
Effector CD4 cell tolerization is mediated through functional inactivation and involves preferential impairment of TNF-α and IFN-γ expression potentials
Meixiao Long, A. Higgins, M. Mihalyo, A. Adler
200324 citations Open access
Semantic Scholar
Self-Antigen Prevents CD8 T Cell Effector Differentiation by CD134 and CD137 Dual Costimulation
Suman Bandyopadhyay, Meixiao Long, H. Qui, Adam T. Hagymasi +6 more
2008Journal of Immunology22 citations Open access
Semantic Scholar

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