Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

G. Serrero · SciRah

Researcher profile · Semantic Scholar

G. Serrero

Share profile

G. Serrero — researcher profile on SciRah

h-index: 40
Works: 191
Citations: 5,618

Most-cited papers

Morphologically and Functionally Distinct Lipid Droplet Subpopulations
Shu-Yan Zhang, Yang Wang, Liu-Juan Cui, Yaqin Deng +6 more
2016Scientific Reports91 citations Open access
Semantic Scholar
Increased Serum GP88 (Progranulin) Concentrations in Rheumatoid Arthritis
Y. Yamamoto, M. Takemura, G. Serrero, J. Hayashi +9 more
2014Inflammation76 citations
Semantic Scholar
Proepithelin regulates prostate cancer cell biology by promoting cell growth, migration, and anchorage-independent growth.
Giada Monamì, Velia Emiliozzi, A. Bitto, Francesca Lovat +8 more
2009American Journal of Pathology75 citations Open access
Semantic Scholar
Progranulin (GP88) tumor tissue expression is associated with increased risk of recurrence in breast cancer patients diagnosed with estrogen receptor positive invasive ductal carcinoma
G. Serrero, D. Hawkins, B. Yue, O. Ioffe +8 more
2012Breast Cancer Research58 citations Open access
Semantic Scholar
GP88 (Progranulin): A novel tissue and circulating biomarker for non-small cell lung carcinoma
M. Edelman, J. Feliciano, B. Yue, P. Bejarano +6 more
2014Human Pathology57 citations Open access
Semantic Scholar
Increased Circulating Level of the Survival Factor GP88 (Progranulin) in the Serum of Breast Cancer Patients When Compared to Healthy Subjects
K. Tkaczuk, B. Yue, M. Zhan, N. Tait +3 more
2011Breast Cancer: Basic and Clinical Research48 citations Open access
Semantic Scholar
Proepithelin is an autocrine growth factor for bladder cancer.
Francesca Lovat, A. Bitto, Shi‐qiong Xu, M. Fassan +9 more
2009Carcinogenesis46 citations Open access
Semantic Scholar
GP88 (PC-Cell Derived Growth Factor, progranulin) stimulates proliferation and confers letrozole resistance to aromatase overexpressing breast cancer cells
T. Abrhale, A. Brodie, G. Sabnis, L. Macedo +3 more
2011BMC Cancer45 citations Open access
Semantic Scholar
Association between increased serum GP88 (progranulin) concentrations and prognosis in patients with malignant lymphomas.
Y. Yamamoto, N. Goto, M. Takemura, Wakana Yamasuge +14 more
2017Clinica chimica acta; international journal of clinical chemistry34 citations
Semantic Scholar
Progranulin levels in blood in Alzheimer's disease and mild cognitive impairment
Yonatan A. Cooper, Daniel Nachun, D. Dokuru, Zhongan Yang +6 more
2018Annals of Clinical and Translational Neurology27 citations Open access
Semantic Scholar
Increased cerebrospinal fluid progranulin correlates with interleukin-6 in the acute phase of neuromyelitis optica spectrum disorder.
Akio Kimura, M. Takemura, Kuniaki Saito, G. Serrero +3 more
2017Journal of Neuroimmunology21 citations
Semantic Scholar
A systematic review of progranulin concentrations in biofluids in over 7,000 people—assessing the pathogenicity of GRN mutations and other influencing factors
Imogen J. Swift, R. Rademakers, N. Finch, Matt Baker +93 more
2024Alzheimer's Research & Therapy20 citations Open access
Semantic Scholar
Association of Serum Progranulin Levels With Disease Progression, Therapy Response and Survival in Patients With Metastatic Breast Cancer
K. Tkaczuk, D. Hawkins, B. Yue, D. Hicks +2 more
2019Clinical Breast Cancer17 citations Open access
Semantic Scholar
Progranulin as a predictive factor of response to chemotherapy in advanced biliary tract carcinoma
Jong-Ho Kim, I. Do, Kyungeun Kim, J. Sohn +12 more
2016Cancer Chemotherapy and Pharmacology16 citations
Semantic Scholar
Expression of GP88 (progranulin) in serum of prostate cancer patients is associated with Gleason scores and overall survival
T. Greither, Kersten Fischer, G. Theil, M. Marcou +10 more
2018Cancer Management and Research15 citations Open access
Semantic Scholar
Higher levels of progranulin in cerebrospinal fluid of patients with lymphoma and carcinoma with CNS metastasis
Akio Kimura, M. Takemura, G. Serrero, N. Yoshikura +3 more
2018Journal of Neuro-Oncology15 citations
Semantic Scholar
Signaling Pathway of GP88 (Progranulin) in Breast Cancer Cells: Upregulation and Phosphorylation of c-myc by GP88/Progranulin in Her2-Overexpressing Breast Cancer Cells
W. Kim, B. Yue, G. Serrero
2015Breast Cancer: Basic and Clinical Research14 citations Open access
Semantic Scholar
Anti-progranulin/GP88 antibody AG01 inhibits triple negative breast cancer cell proliferation and migration
R. Guha, B. Yue, Jianping Dong, Aditi Banerjee +1 more
2021Breast Cancer Research and Treatment13 citations Open access
Semantic Scholar
Effect of PTFGRN Expression on the Proteomic Profile of A431 Cells and Determination of the PTGFRN Interactome
Jorge Marquez, Mehari Weldemariam, Jianping Dong, Jun Hayashi +2 more
2024ACS Omega12 citations Open access
Semantic Scholar
Expression of GP88 (Progranulin) Protein Is an Independent Prognostic Factor in Prostate Cancer Patients
A. Abdulrahman, M. Eckstein, Rudolf Jung, J. Guzman +10 more
2019Cancers12 citations Open access
Semantic Scholar
GP88 (Progranulin) Confers Fulvestrant (Faslodex, ICI 182,780) Resistance to Human Breast Cancer Cells
Wisit Tangkeangsirisin, G. Serrero
201411 citations Open access
Semantic Scholar
Expression of AR-V7 (Androgen Receptor Variant 7) Protein in Granular Cytoplasmic Structures Is an Independent Prognostic Factor in Prostate Cancer Patients
Paul König, M. Eckstein, Rudolf Jung, A. Abdulrahman +11 more
2020Cancers10 citations Open access
Semantic Scholar
Determination of GP88 (progranulin) expression in breast tumor biopsies improves the risk predictive value of the Nottingham Prognostic Index
G. Serrero, D. Hawkins, P. Bejarano, O. Ioffe +8 more
2016Diagnostic Pathology10 citations Open access
Semantic Scholar
Identification of Prostaglandin F2 Receptor Negative Regulator (PTGFRN) as an internalizable target in cancer cells for antibody-drug conjugate development
Jorge Marquez, Jianping Dong, Chunlan Dong, Changsheng Tian +1 more
2021PLoS ONE9 citations Open access
Semantic Scholar
Progranulin depletion inhibits proliferation via the transforming growth factor beta/SMAD family member 2 signaling axis in Kasumi-1 cells
Kuniaki Yabe, Y. Yamamoto, M. Takemura, T. Hara +4 more
2021Heliyon8 citations Open access
Semantic Scholar
Prognostic Value of Progranulin in Patients with Colorectal Cancer Treated with Curative Resection
D. Koo, I. Do, Sukjoong Oh, Yun-Gyoo Lee +12 more
2018Pathology and Oncology Research8 citations
Semantic Scholar
Prostaglandin F2 Receptor Negative Regulator (PTGFRN) Expression Correlates With a Metastatic‐like Phenotype in Epidermoid Carcinoma, Pediatric Medulloblastoma, and Mesothelioma
Jorge Marquez, Jianping Dong, Jun Hayashi, G. Serrero
2024Journal of Cellular Biochemistry7 citations
Semantic Scholar
Progranulin/GP88, A Complex and Multifaceted Player of Tumor Growth by Direct Action and via the Tumor Microenvironment.
G. Serrero
2021Advances in Experimental Medicine and Biology7 citations
Semantic Scholar
Clinicopathological characteristics and outcomes of gastrointestinal stromal tumors with high progranulin expression
I. Do, K. Jung, D. Koo, Yun-Gyoo Lee +12 more
2021PLoS ONE6 citations Open access
Semantic Scholar
GP88/PGRN Serum Levels Are Associated with Prognosis for Oral Squamous Cell Carcinoma Patients
T. Greither, T. Steiner, M. Bache, G. Serrero +4 more
2021Biology6 citations Open access
Semantic Scholar
Potential of Theranostic Target Mining in the Development of Novel Diagnostic and Therapeutic Products in Oncology: Progranulin/GP88 as a Therapeutic and Diagnostic Target for Breast and Lung Cancers.
G. Serrero
2016Rinsho byori. The Japanese journal of clinical pathology5 citations
Semantic Scholar
Combination of GP88 Expression in Tumor Cells and Tumor-Infiltrating Immune Cells Is an Independent Prognostic Factor for Bladder Cancer Patients
M. Eckstein, V. Lieb, Rudolf Jung, D. Sikic +11 more
2021Cells3 citations Open access
Semantic Scholar
Measurement of Circulating Progranulin (PGRN/GP88/GEP) by Enzyme-Linked Immunosorbent Assay and Application in Human Diseases.
G. Serrero, D. Hicks
2018Methods in molecular biology3 citations
Semantic Scholar
A tribute to Dr. Gordon Hisashi Sato (December 24, 1927–March 31, 2017)
J. D. Sato, T. Okamoto, David W. Barnes, Jun Hayashi +2 more
2018In Vitro Cellular & Developmental Biology - Animal3 citations Open access
Semantic Scholar
Combined miR-486 and GP88 (Progranulin) Serum Levels Are Suggested as Supportive Biomarkers for Therapy Decision in Elderly Prostate Cancer Patients
A. Fichte, A. Neumann, K. Weigelt, J. Guzman +11 more
2022Life2 citations Open access
Semantic Scholar
Immunohistochemical Detection of Progranulin (PGRN/GP88/GEP) in Tumor Tissues as a Cancer Prognostic Biomarker.
G. Serrero, D. Hicks
2018Methods in molecular biology2 citations
Semantic Scholar
Progranulin protein plasma and CSF levels in a large well-characterized dementia and healthy aging cohort. (S33.004)
Z. Miller, Laura Mitic, J. Tran, I. Lobach +6 more
2015Neurology2 citations
Semantic Scholar
Abstract P6-04-19: Neutralizing antibody to human GP88 (progranulin) restores sensitivity to tamoxifen and inhibits breast tumor growth in mouse xenografts
G. Serrero, J. Dong, J. Hayashi
20122 citations
Semantic Scholar
Phase 1 first-in-human trial of AG01, a recombinant humanized monoclonal antibody to progranulin/glycoprotein 88 (GP88) to determine the safety, tolerability, pharmacokinetics, and preliminary antitumor activity in subjects with advanced solid tumor malignancies.
K. Tkaczuk, K. Scilla, Gautam G. Rao, Yi-Xing Jiang +6 more
2026Journal of Clinical Oncology1 citations
Semantic Scholar
Phase 1 first-in-human clinical trial of AG01, a recombinant monoclonal antibody to progranulin/glycoprotein 88 (PGRN/GP88), to determine the safety, tolerability, pharmacokinetics, and preliminary anti-tumor response in subjects with advanced solid tumor malignancies.
K. Tkaczuk, P. Rosenblatt, K. Scilla, Ranee Mehra +6 more
2025Journal of Clinical Oncology1 citations
Semantic Scholar
Abstract CT240: On-going phase 1A clinical trial for AG01 an first-in-class anti-progranulin (GP88) monoclonal antibody in patients with advanced malignancies
K. Tkaczuk, P. Rosenblatt, R. Mehra, K. Scilla +4 more
2023Cancer Research1 citations
Semantic Scholar
Abstract 561: Development of competing and non-competing fully human internalizing anti-Her2 monoclonal antibodies
G. Serrero, B. Yue, J. Dong, Chunlan Dong +1 more
2023Cancer Research1 citations
Semantic Scholar
Serum GP88 as a predictive biomarker for hepatocellular carcinoma in patients with viral hepatitis C after direct-acting antiviral agents
H. Ishida, M. Takemura, A. Suetsugu, T. Naiki +6 more
2021Annals of Clinical Biochemistry1 citations
Semantic Scholar
Clinicopathological characteristics of patients with gastrointestinal stromal tumor according to progranulin expression.
D. Koo, I. Do, Sukjoong Oh, Yun-Gyoo Lee +7 more
2019Journal of Clinical Oncology1 citations
Semantic Scholar
Clinical characteristics and outcomes of metastatic or recurrent gastric cancer with high progranulin expression in patients who had received palliative chemotherapy.
D. Koo, I. Do, T. Yoo, Sukjoong Oh +8 more
20181 citations
Semantic Scholar
Abstract 1934: Anti-Progranulin (GP88) antibody AG01 therapeutic effect in triple negative breast cancer invasiveness
R. Guha, Jianping Dong, B. Yue, G. Serrero
2018Experimental and Molecular Therapeutics1 citations
Semantic Scholar
Abstract 4514A: Antibody to Progranulin (Anti-GP88) potentiates tamoxifen and letrozole effect in estrogen receptor positive breast cancer cells
G. Serrero, Jianping Dong, Jorge Marquez, B. Yue +1 more
20141 citations
Semantic Scholar
GP 88 ( Progranulin ) Confers Fulvestrant ( Faslodex , ICI 182 , 780 ) Resistance to Human Breast Cancer Cells
Wisit Tangkeangsirisin, G. Serrero
20141 citations
Semantic Scholar
Abstract 2054: GP88 (Progranulin) is a therapeutic and prognostic target for Non-Small Cell Lung Carcinoma.
G. Serrero, G. Xia, Jianping Dong, B. Yue +5 more
20131 citations
Semantic Scholar
Abstract P2-10-40: Correlation between expression of the prognostic marker Progranulin (GP88) with Oncotype Dx Recurrence Score in estrogen receptor positive breast tumors
G. Serrero, M. Koka, L. Goicochea, K. Tkaczuk +5 more
20121 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

B. Yue×22
Invite
B. Yue — researcher profile on SciRah
K. Tkaczuk×8
Invite
K. Tkaczuk — researcher profile on SciRah
M. Takemura×6
Invite
M. Takemura — researcher profile on SciRah
D. Hicks×6
Invite
D. Hicks — researcher profile on SciRah

×6

Invite

H. Taubert — researcher profile on SciRah

Invite

J. Hayashi — researcher profile on SciRah

Kuniaki Saito×5

Invite

Kuniaki Saito — researcher profile on SciRah

Invite

D. Hawkins — researcher profile on SciRah

Invite

N. Tait — researcher profile on SciRah

Invite

I. Do — researcher profile on SciRah

Kyungeun Kim×5

Invite

Kyungeun Kim — researcher profile on SciRah

Invite

J. Sohn — researcher profile on SciRah