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S. Gendler · SciRah

Researcher profile · Semantic Scholar

S. Gendler

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S. Gendler — researcher profile on SciRah

h-index: 72
Works: 233
Citations: 18K

Most-cited papers

Structure and function of the cell surface (tethered) mucins.
Christine L. Hattrup, S. Gendler
2008Annual Review of Physiology765 citations
Semantic Scholar
MUC1 cell surface mucin is a critical element of the mucosal barrier to infection.
J. McAuley, Sara K. Lindén, C. Png, R. King +6 more
2007Journal of Clinical Investigation430 citations Open access
Semantic Scholar
Importance and regulation of the colonic mucus barrier in a mouse model of colitis.
Joel Petersson, O. Schreiber, G. Hansson, S. Gendler +5 more
2011American Journal of Physiology - Gastrointestinal and Liver Physiology379 citations Open access
Semantic Scholar
Immune recognition of tumor-associated mucin MUC1 is achieved by a fully synthetic aberrantly glycosylated MUC1 tripartite vaccine
V. Lakshminarayanan, Pamela Thompson, M. Wolfert, T. Buskas +6 more
2011Proceedings of the National Academy of Sciences of the United States of America292 citations Open access
Semantic Scholar
MUC1 enhances invasiveness of pancreatic cancer cells by inducing epithelial to mesenchymal transition
L. Das Roy, M. Sahraei, Durai B. Subramani, Dahlia M. Besmer +8 more
2010Oncogene275 citations Open access
Semantic Scholar
Regulation of mucin genes in chronic inflammatory airway diseases.
J. Voynow, S. Gendler, M. Rose
2006American Journal of Respiratory Cell and Molecular Biology209 citations
Semantic Scholar
MUC1 mucin is a negative regulator of toll-like receptor signaling.
Keiko Ueno, Takeshi Koga, Kosuke Kato, D. Golenbock +3 more
2008American Journal of Respiratory Cell and Molecular Biology175 citations Open access
Semantic Scholar
Mechanisms underlying the growth inhibitory effects of the cyclo-oxygenase-2 inhibitor celecoxib in human breast cancer cells
G. Basu, Latha B. Pathangey, Teresa L. Tinder, S. Gendler +1 more
2005Breast Cancer Research159 citations Open access
Semantic Scholar
Cutting Edge: Enhanced Pulmonary Clearance of Pseudomonas aeruginosa by Muc1 Knockout Mice1
Wen-Ju Lu, A. Hisatsune, Takeshi Koga, Kosuke Kato +7 more
2006Journal of Immunology145 citations Open access
Semantic Scholar
The gastric mucus layers: constituents and regulation of accumulation.
M. Phillipson, M. Johansson, J. Henriksnäs, J. Petersson +5 more
2008American Journal of Physiology - Gastrointestinal and Liver Physiology133 citations
Semantic Scholar
Pancreatic cancer pain and its correlation with changes in tumor vasculature, macrophage infiltration, neuronal innervation, body weight and disease progression
T. H. Lindsay, Beth M. Jonas, Molly A. Sevcik, K. Kubota +8 more
2005Pain120 citations
Semantic Scholar
Pancreatic Ductal Adenocarcinoma (PDA) mice lacking Mucin 1 have a profound defect in tumor growth and metastasis
Dahlia M. Besmer, J. Curry, L. Das Roy, Teresa L. Tinder +6 more
2011Cancer Research115 citations Open access
Semantic Scholar
Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells.
P. Singh, Yun-Fei Wen, Benjamin J. Swanson, K. Shanmugam +4 more
2007Cancer Research109 citations Open access
Semantic Scholar
MUC1 alters oncogenic events and transcription in human breast cancer cells
Christine L. Hattrup, S. Gendler
2006Breast Cancer Research105 citations Open access
Semantic Scholar
Phosphorylation of MUC1 by Met Modulates Interaction with p53 and MMP1 Expression*
P. Singh, Michelle E. Behrens, John P. Eggers, R. Cerny +5 more
2008Journal of Biological Chemistry95 citations Open access
Semantic Scholar
In vivo Radioiodide Imaging and Treatment of Breast Cancer Xenografts after MUC1-Driven Expression of the Sodium Iodide Symporter
R. Dwyer, E. Bergert, M. O'Connor, S. Gendler +1 more
2005Clinical Cancer Research89 citations Open access
Semantic Scholar
MUC1 Regulates PDGFA Expression During Pancreatic Cancer Progression
M. Sahraei, L. Das Roy, J. Curry, Tinder L Teresa +6 more
2012Oncogene82 citations Open access
Semantic Scholar
MUC1-specific immune therapy generates a strong anti-tumor response in a MUC1-tolerant colon cancer model.
P. Mukherjee, Latha B. Pathangey, J. B. Bradley, Teresa L. Tinder +3 more
2007Vaccine78 citations Open access
Semantic Scholar
Peroxisome Proliferator-Activated Receptor γ Controls Muc1 Transcription in Trophoblasts
Tali Shalom-Barak, Jill M. Nicholas, Yong-Xu Wang, Xiaowen Zhang +5 more
2004Molecular and Cellular Biology78 citations Open access
Semantic Scholar
Sodium iodide symporter-mediated radioiodide imaging and therapy of ovarian tumor xenografts in mice
R. Dwyer, E. Bergert, M. O'Connor, S. Gendler +1 more
2006Gene Therapy76 citations Open access
Semantic Scholar
Adenovirus-Mediated and Targeted Expression of the Sodium–Iodide Symporter Permits In Vivo Radioiodide Imaging and Therapy of Pancreatic Tumors
R. Dwyer, E. Bergert, M. O'Connor, S. Gendler +1 more
2006Human Gene Therapy70 citations Open access
Semantic Scholar
Increased levels of mucins in the cystic fibrosis mouse small intestine, and modulator effects of the Muc1 mucin expression.
Emily K Malmberg, Karin Noaksson, M. Phillipson, M. Johansson +4 more
2006American Journal of Physiology - Gastrointestinal and Liver Physiology69 citations
Semantic Scholar
Muc1 affects c-Src signaling in PyV MT-induced mammary tumorigenesis
Azzah Al Masri, S. Gendler
2005Oncogene63 citations Open access
Semantic Scholar
Tumor‐associated carbohydrate antigens: A possible avenue for cancer prevention
Yan-Fei Xu, A. Sette, J. Sidney, S. Gendler +1 more
2005Immunology and Cell Biology63 citations
Semantic Scholar
MUC1 (CD227) interacts with lck tyrosine kinase in Jurkat lymphoma cells and normal T cells
P. Mukherjee, Teresa L. Tinder, G. Basu, S. Gendler
2005Journal of Leukocyte Biology62 citations
Semantic Scholar
Immune and Anticancer Responses Elicited by Fully Synthetic Aberrantly Glycosylated MUC1 Tripartite Vaccines Modified by a TLR2 or TLR9 Agonist
Abu-Baker M. Abdel-Aal, V. Lakshminarayanan, Pamela Thompson, N. Supekar +5 more
2014ChemBioChem61 citations Open access
Semantic Scholar
Recombinant plant-expressed tumour-associated MUC1 peptide is immunogenic and capable of breaking tolerance in MUC1.Tg mice.
J. Pinkhasov, M. L. Alvarez, M. Rigano, Khanrat Piensook +7 more
2011Plant Biotechnology Journal56 citations
Semantic Scholar
Tyrosines in the MUC1 Cytoplasmic Tail Modulate Transcription via the Extracellular Signal-Regulated Kinase 1/2 and Nuclear Factor-κB Pathways
E. J. Thompson, K. Shanmugam, Christine L. Hattrup, Kari L. Kotlarczyk +4 more
2006Molecular Cancer Research53 citations
Semantic Scholar
Modification of the Tumor Microenvironment as a Novel Target of Renal Cell Carcinoma Therapeutics
J. Finke, P. Rayman, J. Ko, Judy M. Bradley +2 more
2013Cancer Journal49 citations Open access
Semantic Scholar
MUC1 Vaccines, Comprised of Glycosylated or Non-Glycosylated Peptides or Tumor-Derived MUC1, Can Circumvent Immunoediting to Control Tumor Growth in MUC1 Transgenic Mice
V. Lakshminarayanan, N. Supekar, Jie Wei, Dustin McCurry +11 more
2016PLoS ONE48 citations Open access
Semantic Scholar
Inhibition of adaptive immunity by IL-9 can be disrupted to achieve rapid T cell sensitization and rejection of progressive tumor challenges
D. Hoelzinger, A. Dominguez, P. Cohen, S. Gendler
2014Cancer Research48 citations Open access
Semantic Scholar
Myeloid-derived Suppressor Cells Adhere to Physiologic STAT3- vs STAT5-dependent Hematopoietic Programming, Establishing Diverse Tumor-Mediated Mechanisms of Immunologic Escape
P. Cohen, J. Ko, W. Storkus, Christopher D. Spencer +10 more
2012Immunological Investigations42 citations Open access
Semantic Scholar
Expression of Human MUC1 During Early Pregnancy in the Human MUC1 Transgenic Mouse Model1
N. Dharmaraj, S. Gendler, D. Carson
2009Biology of Reproduction42 citations Open access
Semantic Scholar
Evidence that gallbladder epithelial mucin enhances cholesterol cholelithogenesis in MUC1 transgenic mice.
Helen H. Wang, N. Afdhal, S. Gendler, D. Q. Wang
2006Gastroenterology42 citations
Semantic Scholar
Muc1 is protective during kidney ischemia-reperfusion injury.
N. Pastor-Soler, T. A. Sutton, Henry E. Mang, C. Kinlough +11 more
2015AJP - Renal Physiology40 citations Open access
Semantic Scholar
Linear synthesis and immunological properties of a fully synthetic vaccine candidate containing a sialylated MUC1 glycopeptide
Pamela Thompson, V. Lakshminarayanan, N. Supekar, Judy M. Bradley +4 more
2015Chemical Communications39 citations Open access
Semantic Scholar
Core-glycosylated Mucin-like Repeats from MUC1 Are an Apical Targeting Signal*
C. Kinlough, P. Poland, S. Gendler, Polly E. Mattila +3 more
2011Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Lack of Muc1-regulated beta-catenin stability results in aberrant expansion of CD11b+Gr1+ myeloid derived suppressor cells from the bone marrow
T. W. Poh, Judy M. Bradley, P. Mukherjee, S. Gendler
2009Cancer Research37 citations Open access
Semantic Scholar
MUC1 cytoplasmic tail detection using CT33 polyclonal and CT2 monoclonal antibodies in breast and colorectal tissue.
M. Croce, M. Isla-Larrain, F. Remes-Lenicov, A. Colussi +4 more
2006Histology and Histopathology33 citations
Semantic Scholar
The MUC1 Cytoplasmic Tail and Tandem Repeat Domains Contribute to Mammary Oncogenesis in FVB Mice
Christine L. Hattrup, Judy M. Bradley, Kari L. Kotlarczyk, C. Madsen +3 more
2008Breast Cancer: Basic and Clinical Research31 citations Open access
Semantic Scholar
Human Breast Cancer Stem Cells Have Significantly Higher Rate of Clathrin-Independent and Caveolin-Independent Endocytosis than the Differentiated Breast Cancer Cells
Kanagaraj Palaniyandi, B. Pockaj, S. Gendler, X. Chang
2012Journal of Cancer Science & Therapy30 citations Open access
Semantic Scholar
Intratumoral delivery of CpG-conjugated anti-MUC1 antibody enhances NK cell anti-tumor activity
Jorge L. Schettini, A. Kidiyoor, Dahlia M. Besmer, Teresa L. Tinder +4 more
2012Cancer Immunology and Immunotherapy29 citations Open access
Semantic Scholar
MUC4 mucin expression in human pancreatic tumours is affected by organ environment: the possible role of TGFβ2
A. Choudhury, N. Moniaux, A. Ulrich, B. Schmied +6 more
2004British Journal of Cancer29 citations Open access
Semantic Scholar
Muc1 enhances the β-catenin protective pathway during ischemia-reperfusion injury.
M. Al-Bataineh, C. Kinlough, P. Poland, N. Pastor-Soler +8 more
2016AJP - Renal Physiology27 citations Open access
Semantic Scholar
Definitive activation of endogenous antitumor immunity by repetitive cycles of cyclophosphamide with interspersed Toll-like receptor agonists
S. Z. Manrique, A. Dominguez, Noweeda N. Mirza, Christopher D. Spencer +6 more
2016OncoTarget23 citations Open access
Semantic Scholar
A Flow Cytometry‐Based Assay for Procoagulant Platelet Polyphosphate
L. Labberton, Andy T. Long, S. Gendler, Christine L. H. Snozek +6 more
2018Cytometry. Part B, Clinical cytometry21 citations Open access
Semantic Scholar
Down regulation of hematopoietic MUC1 during experimental colitis increases tumor promoting myeloid-derived suppressor cells
T. W. Poh, C. Madsen, Jessica E. Gorman, R. Marler +3 more
2013Clinical Cancer Research21 citations Open access
Semantic Scholar
Targeted imaging of breast tumor progression and therapeutic response in a human uMUC-1 expressing transgenic mouse model
Subrata K. Ghosh, Masashi Uchida, B. Yoo, Alana W. Ross +4 more
2012International Journal of Cancer21 citations Open access
Semantic Scholar
Telomerase deficiency and telomere dysfunction inhibit mammary tumors induced by polyomavirus middle T oncogene
M. Jaskelioff, W. Song, J. Xia, Chunlei Liu +5 more
2009Oncogene21 citations Open access
Semantic Scholar
Surrogate in vitro activation of innate immunity synergizes with interleukin-7 to unleash rapid antigen-driven outgrowth of CD4+ and CD8+ human peripheral blood T-cells naturally recognizing MUC1, HER2/neu and other tumor-associated antigens
Latha B. Pathangey, Dustin McCurry, S. Gendler, A. Dominguez +6 more
2016OncoTarget17 citations Open access
Semantic Scholar

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Latha B. Pathangey×6
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Teresa L. Tinder×6

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