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J. Mortensen · SciRah

Researcher profile · Semantic Scholar

J. Mortensen

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J. Mortensen — researcher profile on SciRah

h-index: 19
Works: 126
Citations: 1,457

Most-cited papers

The good and the bad collagens of fibrosis – Their role in signaling and organ function
M. Karsdal, S. Nielsen, D. Leeming, L. Langholm +9 more
2017Advanced Drug Delivery Reviews465 citations
Semantic Scholar
ECM formation and degradation during fibrosis, repair, and regeneration
A. Mayorca‐Guiliani, D. Leeming, Kim Henriksen, J. Mortensen +5 more
2025npj Metabolic Health and Disease150 citations Open access
Semantic Scholar
Misbalance in type III collagen formation/degradation as a novel serological biomarker for penetrating (Montreal B3) Crohn's disease
W. T. van Haaften, J. Mortensen, M. Karsdal, A. Bay-Jensen +2 more
2017Alimentary Pharmacology and Therapeutics60 citations Open access
Semantic Scholar
Enzymatic cross-linking of collagens in organ fibrosis – resolution and assessment
M. Pehrsson, J. Mortensen, T. Manon-Jensen, A. Bay-Jensen +2 more
2021Expert Review of Molecular Diagnostics44 citations
Semantic Scholar
Extracellular Matrix Fragments of the Basement Membrane and the Interstitial Matrix Are Serological Markers of Intestinal Tissue Remodeling and Disease Activity in Dextran Sulfate Sodium Colitis
M. Lindholm, T. Manon-Jensen, G. Madsen, A. Krag +3 more
2019Digestive Diseases and Sciences30 citations Open access
Semantic Scholar
Serological biomarkers of type I, III and IV collagen turnover are associated with the presence and future progression of stricturing and penetrating Crohnʼs disease
A. Bourgonje, M. Alexdóttir, Antonius T. Otten, R. Loveikyte +10 more
2022Alimentary Pharmacology and Therapeutics28 citations Open access
Semantic Scholar
Advances in Extracellular Matrix-Associated Diagnostics and Therapeutics
M. Karsdal, T. Cox, A. Parker, N. Willumsen +43 more
2025Journal of Clinical Medicine24 citations Open access
Semantic Scholar
Serological Biomarkers of Tissue Turnover Identify Responders to Anti-TNF Therapy in Crohn's Disease: A Pilot Study
W. T. van Haaften, J. Mortensen, A. Dige, H. Grønbæk +6 more
2020Clinical and Translational Gastroenterology23 citations Open access
Semantic Scholar
The VICM biomarker is released from activated macrophages and inhibited by anti-GM-CSFRα-mAb treatment in rheumatoid arthritis patients.
J. Mortensen, Xiang Guo, M. de los Reyes, M. Dziegiel +3 more
2019Clinical and Experimental Rheumatology23 citations
Semantic Scholar
Prognostic value of blood-based fibrosis biomarkers in patients with metastatic colorectal cancer receiving chemotherapy and bevacizumab
N. Nissen, S. Kehlet, Mogens K. Boisen, M. Liljefors +8 more
2020Scientific Reports21 citations Open access
Semantic Scholar
Serum type XVI collagen is associated with colorectal cancer and ulcerative colitis indicating a pathological role in gastrointestinal disorders
C. Jensen, S. Nielsen, J. Mortensen, J. Kjeldsen +6 more
2018Cancer Medicine21 citations Open access
Semantic Scholar
An MMP‐degraded and cross‐linked fragment of type III collagen as a non‐invasive biomarker of hepatic fibrosis resolution
M. Pehrsson, T. Manon-Jensen, Shu Sun, I. Villesen +9 more
2022Liver international (Print)20 citations Open access
Semantic Scholar
A Fragment of Collagen Type VI alpha-3 chain is Elevated in Serum from Patients with Gastrointestinal Disorders
S. Holm Nielsen, J. Mortensen, N. Willumsen, D. Rasmussen +11 more
2020Scientific Reports20 citations Open access
Semantic Scholar
Serological Biomarkers of Extracellular Matrix Turnover and Neutrophil Activity Are Associated with Long-Term Use of Vedolizumab in Patients with Crohn’s Disease
M. Alexdóttir, A. Bourgonje, M. Karsdal, M. Pehrsson +8 more
2022International Journal of Molecular Sciences18 citations Open access
Semantic Scholar
Endotrophin and C6Ma3, serological biomarkers of type VI collagen remodelling, reflect endoscopic and clinical disease activity in IBD
M. Lindholm, L. E. Godskesen, T. Manon-Jensen, J. Kjeldsen +3 more
2021Scientific Reports16 citations Open access
Semantic Scholar
Considerations for understanding protein measurements: Identification of formation, degradation and more pathological relevant epitopes.
M. Karsdal, F. Genovese, D. Rasmussen, A. Bay-Jensen +11 more
2021Clinical Biochemistry16 citations
Semantic Scholar
A Specific Calprotectin Neo-epitope [CPa9-HNE] in Serum from Inflammatory Bowel Disease Patients Is Associated with Neutrophil Activity and Endoscopic Severity
J. Mortensen, D. Sinkeviciute, T. Manon-Jensen, V. Domislović +8 more
2022Journal of Crohn's & Colitis15 citations Open access
Semantic Scholar
Serological Assessment of the Quality of Wound Healing Processes in Crohn's Disease.
Shu Sun, M. Karsdal, J. Mortensen, Yunyun Luo +5 more
2019Journal of Gastrointestinal and Liver Diseases15 citations Open access
Semantic Scholar
Type V Collagen is Persistently Altered After Inguinal Hernia Repair
L. Lorentzen, N. Henriksen, P. Juhl, J. Mortensen +3 more
2018Scandinavian Journal of Surgery14 citations Open access
Semantic Scholar
The Citrullinated and MMP-degraded Vimentin Biomarker (VICM) Predicts Early Response to Anti-TNFα Treatment in Crohn’s Disease
J. Mortensen, W. T. van Haaften, M. Karsdal, A. Bay-Jensen +6 more
2020Journal of Clinical Gastroenterology13 citations Open access
Semantic Scholar
Serological Biomarkers of Intestinal Collagen Turnover Identify Early Response to Infliximab Therapy in Patients With Crohn’s Disease
M. Alexdóttir, A. Bourgonje, M. Karsdal, M. Pehrsson +8 more
2022Frontiers in Medicine12 citations Open access
Semantic Scholar
Extracellular matrix remodeling proteins as biomarkers for clinical assessment and treatment outcomes in eosinophilic esophagitis
M. Pehrsson, W. D. de Rooij, A. Bay-Jensen, M. Karsdal +2 more
2023BMC Gastroenterology11 citations Open access
Semantic Scholar
A Serological Neoepitope Biomarker of Neutrophil Elastase-Degraded Calprotectin, Associated with Neutrophil Activity, Identifies Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease More Effectively Than Total Calprotectin
A. Hansen, J. Mortensen, S. Rønnow, M. Karsdal +2 more
2023Journal of Clinical Medicine10 citations Open access
Semantic Scholar
Prognostic value of blood-based fibrosis biomarkers in patients with metastatic colorectal cancer receiving chemotherapy and bevacizumab
N. Nissen, S. Kehlet, Mogens K. Boisen, M. Liljefors +8 more
2021Scientific Reports10 citations Open access
Semantic Scholar
Type XII collagen
J. Mortensen, T. Manon-Jensen, M. Karsdal
2019Biochemistry of Collagens, Laminins and Elastin8 citations
Semantic Scholar
Initiation of the Wound Healing Cascade in Inflammatory Bowel Disease: Assessment of Von Willebrand Factor ADAMTS-13 Processing and Formation in Crohn’s Disease
T. Manon-Jensen, L. Langholm, Shu Sun, J. Mortensen +5 more
20196 citations
Semantic Scholar
Circulating Extracellular Matrix Products as Indicators of Disease Burden and Predictors of Disease Course in Ulcerative Colitis.
Anja Poulsen, M. Alexdóttir, L. Riis, M. Pehrsson +8 more
2024Inflammatory Bowel Diseases4 citations
Semantic Scholar
Neutrophil-mediated type IV collagen degradation is elevated in patients with mild endoscopic ulcerative colitis reflecting early mucosal destruction
M. Alexdóttir, M. Pehrsson, V. Domislović, L. E. Godskesen +8 more
2024Scientific Reports4 citations Open access
Semantic Scholar
Blood-Based Biomarkers Reflecting Protease 3 and MMP-12 Catalyzed Elastin Degradation as Potential Noninvasive Surrogate Markers of Endoscopic and Clinical Disease in Inflammatory Bowel Disease
M. Pehrsson, V. Domislović, M. Alexdóttir, M. Brinar +4 more
2023Journal of Clinical Medicine4 citations Open access
Semantic Scholar
A Serological Biomarker of Laminin Gamma 1 Chain Degradation Reflects Altered Basement Membrane Remodeling in Crohn’s Disease and DSS Colitis
M. Lindholm, A. Di Sabatino, T. Manon-Jensen, G. Mazza +7 more
2021Digestive Diseases and Sciences4 citations Open access
Semantic Scholar
Novel biomarker profiles to improve individual diagnosis and prognosis in patients with suspected inflammatory bowel disease: protocol for the Nordic inception cohort study (NORDTREAT)
A. Fejrskov, Johannes David Füchtbauer, Lóa G. Davíðsdóttir, J. Halfvarson +11 more
2024BMJ Open2 citations Open access
Semantic Scholar
Abstract 386: Evaluation of CPa9-HNE - a peripheral biomarker based on neutrophil extracellular traps (NETs) - for predicting outcome in patients with metastatic melanoma treated with anti-PD-1 therapy
C. Jensen, A. Kverneland, M. Donia, J. Mortensen +3 more
2021Clinical research2 citations
Semantic Scholar
P301 A serological biomarker of type VIII collagen that contains the anti-angiogenic signalling molecule, vastatin, is associated with the extension of disease in ulcerative colitis
M. Lindholm, L. E. Godskesen, L. Langholm, J. Kjeldsen +4 more
2019Journal of Crohn's & Colitis2 citations
Semantic Scholar
Type VII collagen
J. Mortensen, M. Karsdal
2019Biochemistry of Collagens, Laminins and Elastin2 citations
Semantic Scholar
Serological assessment of PRO-C16 (type XVI collagen formation) reflects intestinal fibrostenotic strictures in patients with crohn’s disease
J. Mortensen, M. Lindholm, L. Langholm, P. Giuffrida +9 more
2025BMC Gastroenterology1 citations Open access
Semantic Scholar
P318 Protein FingerPrint assays reflecting neutrophil activity, mucosal damage, and tissue fibrosis are surrogate biomarkers for mucosal healing in pediatric Crohn’s disease
J. Mortensen, G. Focht, M. Pehrsson, A. Griffiths +7 more
2023Journal of Crohn's & Colitis1 citations
Semantic Scholar
Citrullinated and MMP-degraded vimentin is associated with chronic pulmonary diseases and genetic variants in PADI3/PADI4 and CFH in postmenopausal women
C. Bager, J. Blair, M. Tang, J. Mortensen +5 more
2023Scientific Reports1 citations Open access
Semantic Scholar
P197 A biomarker of early mucosal destruction: Neutrophil-mediated type IV collagen degradation is elevated in patients with Crohn’s Disease and Ulcerative Colitis
M. Alexdóttir, M. Pehrsson, M. Karsdal, L. E. Godskesen +3 more
2023Journal of Crohn's & Colitis1 citations Open access
Semantic Scholar
P154 Evaluation of serum protein FingerPrint biomarkers of collagen, citrullinated vimentin and calprotectin in patients with inflammatory bowel disease
Y. Luo, J. Saini, J. Mortensen, A. Bay-Jensen +3 more
2022Journal of Crohn's & Colitis1 citations
Semantic Scholar
Mo1524: SEROLOGICAL BIOMARKERS OF TYPE VI AND XXII COLLAGEN FORMATION PREDICT AND MONITOR INFLIXIMAB TREATMENT RESPONSE IN PATIENTS WITH CROHN’S DISEASE
M. Alexdóttir, A. Bourgonje, M. Karsdal, A. Bay-Jensen +9 more
2022Gastroenterology1 citations
Semantic Scholar
P204 Endotrophin (PRO-C6) is associated with MRE confirmed intestinal strictures and Protein FingerPrint biomarkers of collagen degradation is associated with ulcerations in paediatric Crohn’s disease patients – results from the ImageKids study
J. Mortensen, G. Focht, M. Pehrsson, A. Griffiths +7 more
2022Journal of Crohn's & Colitis1 citations Open access
Semantic Scholar
P127 Type I collagen degradation fragments (C1M) and human neutrophil elastase-derived fragments of calprotectin (CPa9-HNE) reflect biochemical and endoscopic disease activity in patients with Inflammatory Bowel Disease
A. Bourgonje, M. Alexdóttir, R. Loveikyte, M. Pehrsson +9 more
2022Journal of Crohn's & Colitis1 citations Open access
Semantic Scholar
P460 Biomarkers reflecting extracellular matrix turnover and inflammation can be used to monitor disease activity and treatment response in patients with Crohn’s disease undergoing infliximab induction therapy
M. Alexdóttir, A. Bourgonje, M. Karsdal, A. Bay-Jensen +8 more
20211 citations
Semantic Scholar
Su435 BIOMARKERS OF EXTRACELLULAR MATRIX REMODELING IDENTIFY RESPONDERS TO VEDOLIZUMAB THERAPY IN SUBJECTS WITH ULCERATIVE COLITIS IN THE GEMINI I STUDY
J. Mortensen, A. Bay-Jensen, M. Karsdal, D. Ostanin +3 more
20211 citations
Semantic Scholar
P516 Serological biomarkers of tissue remodeling are associated with endoscopic remission in Crohn’s disease patients treated with GED-0301 (mongersen)
J. Mortensen, B. Feagan, A. Bay-Jensen, M. Karsdal +3 more
20211 citations Open access
Semantic Scholar
P316 Human neutrophil elastase derived fragment of calprotectin (S100a9) is a serum biomarker (CPa9-HNE) for monitoring of anti-TNFα treatment response in Crohn’s disease
J. Mortensen, M. Karsdal, H. Grønbæk, C. Hvas +2 more
20211 citations Open access
Semantic Scholar
21 Neutrophil extracellular traps (NETs) can be measured non-invasively with CPa9-HNE – biomarker potential across different solid tumor types in the immuno-oncology setting
C. Jensen, J. Thorlacius-Ussing, J. Mortensen, M. Karsdal +1 more
2021Journal for ImmunoTherapy of Cancer1 citations Open access
Semantic Scholar
P235 Serological biomarkers of interstitial matrix and basement membrane remodelling correlate the Modified Mayo Endoscopic Score (mMES) for ulcerative colitis
J. Mortensen, L. E. Godskesen, M. Lindholm, A. Krag +3 more
20201 citations Open access
Semantic Scholar
P047 Differences in extra cellular matrix remodelling in highly active Crohn’s disease and ulcerative colitis
V. Domislović, J. Mortensen, M. Karsdal, M. Brinar +2 more
20201 citations
Semantic Scholar
Mo1822 – Elevated Ectodomain of Type 23 Collagen is a Novel Biomarker of the Intestinal Epithelium to Monitor Disease Activity in Ulcerative Colitis and in Crohns Disease
T. Manon-Jensen, Shu Sun, M. Lindholm, Ž. Krznarić +8 more
2019Gastroenterology1 citations Open access
Semantic Scholar

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M. Karsdal×31
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M. Karsdal — researcher profile on SciRah
T. Manon-Jensen×18
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A. Bay-Jensen×18
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M. Pehrsson×14
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D. Leeming — researcher profile on SciRah

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