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Sinéad T. Aherne · SciRah

Researcher profile · Semantic Scholar

Sinéad T. Aherne

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Sinéad T. Aherne — researcher profile on SciRah

h-index: 15
Works: 51
Citations: 1,557

Most-cited papers

Correlating transcriptional networks to breast cancer survival: a large-scale coexpression analysis.
Colin Clarke, S. Madden, P. Doolan, Sinéad T. Aherne +8 more
2013Carcinogenesis387 citations Open access
Semantic Scholar
BreastMark: An Integrated Approach to Mining Publicly Available Transcriptomic Datasets Relating to Breast Cancer Outcome
S. Madden, Colin Clarke, Patricia Gaule, Sinéad T. Aherne +4 more
2013Breast Cancer Research132 citations Open access
Semantic Scholar
A Simplified Method to Recover Urinary Vesicles for Clinical Applications, and Sample Banking
L. Musante, Dorota Tataruch, D. Gu, A. Benito-Martin +3 more
2014Scientific Reports123 citations Open access
Semantic Scholar
Comparison of miRNA expression patterns using total RNA extracted from matched samples of formalin-fixed paraffin-embedded (FFPE) cells and snap frozen cells
Jing-Huan Li, P. Smyth, R. Flavin, S. Cahill +5 more
2007BMC Biotechnology123 citations Open access
Semantic Scholar
Altered eIF6 and Dicer expression is associated with clinicopathological features in ovarian serous carcinoma patients
R. Flavin, P. Smyth, S. Finn, A. Laios +13 more
2008Modern Pathology108 citations Open access
Semantic Scholar
Integrated miRNA, mRNA and protein expression analysis reveals the role of post-transcriptional regulation in controlling CHO cell growth rate
Colin Clarke, M. Henry, P. Doolan, Shane Kelly +11 more
2012BMC Genomics94 citations Open access
Semantic Scholar
Potentially important microRNA cluster on chromosome 17p13.1 in primary peritoneal carcinoma
R. Flavin, P. Smyth, A. Laios, S. O'Toole +14 more
2009Modern Pathology92 citations Open access
Semantic Scholar
Improved RNA quality and TaqMan® Pre-amplification method (PreAmp) to enhance expression analysis from formalin fixed paraffin embedded (FFPE) materials
Jing-Huan Li, P. Smyth, S. Cahill, K. Denning +6 more
2008BMC Biotechnology92 citations Open access
Semantic Scholar
Circulating miRNAs miR-34a and miR-150 associated with colorectal cancer progression
Sinéad T. Aherne, S. Madden, D. Hughes, B. Pardini +6 more
2015BMC Cancer91 citations Open access
Semantic Scholar
MiR-7 Triggers Cell Cycle Arrest at the G1/S Transition by Targeting Multiple Genes Including Skp2 and Psme3
Noelia Sánchez, M. Gallagher, N. Lao, C. Gallagher +7 more
2013PLoS ONE61 citations Open access
Semantic Scholar
A molecular expression signature distinguishing follicular lesions in thyroid carcinoma using preamplification RT-PCR in archival samples
K. Denning, P. Smyth, S. Cahill, S. Finn +8 more
2007Modern Pathology36 citations Open access
Semantic Scholar
Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines
F. O'Neill, S. Madden, Sinéad T. Aherne, M. Clynes +3 more
2012Molecular Cancer35 citations Open access
Semantic Scholar
Transcriptomic analysis of clonal growth rate variation during CHO cell line development.
P. Doolan, Colin Clarke, P. Kinsella, L. Breen +6 more
2013Journal of Biotechnology30 citations
Semantic Scholar
Regulation of microRNA biosynthesis and expression in 2102Ep embryonal carcinoma stem cells is mirrored in ovarian serous adenocarcinoma patients
Michael F. Gallagher, R. Flavin, S. Elbaruni, Jamie McInerney +13 more
2009Journal of Ovarian Research26 citations Open access
Semantic Scholar
A gene expression profile indicative of early stage HER2 targeted therapy response
F. O'Neill, S. Madden, M. Clynes, J. Crown +3 more
2013Molecular Cancer25 citations Open access
Semantic Scholar
The prognostic utility of the transcription factor SRF in docetaxel-resistant prostate cancer: in-vitro discovery and in-vivo validation
D. Lundon, A. Boland, M. Prencipe, G. Hurley +9 more
2017BMC Cancer15 citations Open access
Semantic Scholar
Parallel mRNA, proteomics and miRNA expression analysis in cell line models of the intestine
F. O'Sullivan, J. Keenan, Sinéad T. Aherne, F. O'Neill +9 more
2017World Journal of Gastroenterology13 citations Open access
Semantic Scholar
Altered expression of mir-222 and mir-25 influences diverse gene expression changes in transformed normal and anaplastic thyroid cells, and impacts on MEK and TRAIL protein expression
Sinéad T. Aherne, P. Smyth, Michael Freeley, L. Smith +3 more
2016International Journal of Molecular Medicine12 citations Open access
Semantic Scholar
Olfactomedin III expression contributes to anoikis-resistance in clonal variants of a human lung squamous carcinoma cell line.
J. Keenan, H. Joyce, Sinéad T. Aherne, S. O'Dea +3 more
2012Experimental Cell Research10 citations Open access
Semantic Scholar
ret/PTC-1 expression alters the immunoprofile of thyroid follicular cells
K. Denning, P. Smyth, S. Cahill, Jing-Huan Li +4 more
2008Molecular Cancer10 citations Open access
Semantic Scholar
RET/PTC Rearrangement Occurring in Primary Peritoneal Carcinoma
R. Flavin, G. Jackl, S. Finn, P. Smyth +12 more
2009International Journal of Surgical Pathology9 citations
Semantic Scholar
Comparative transcriptomic analysis of cultivated limbal epithelium and donor corneal tissue reveals altered wound healing gene expression.
C. Gallagher, Colin Clarke, Sinéad T. Aherne, K. Katikireddy +8 more
2014Investigative Ophthalmology and Visual Science8 citations
Semantic Scholar
The Terry Fox Research Institute Marathon of Hope Cancer Centres Network: A pan-Canadian precision oncology initiative.
Tess Aalto, M. Abacan, S. Abadi, F. Aghababazadeh +496 more
2025Cancer Cell5 citations
Semantic Scholar
EpiATLAS – a reference for human epigenomic research
Quirin Manz, M. Bilenky, Dennis Hecker, Nihit Aggarwal +144 more
2026bioRxiv4 citations Open access
Semantic Scholar
Manipulating MiRNA Expression to Uncover Hidden Functions.
Sinéad T. Aherne, N. Lao
2017Methods in molecular biology4 citations
Semantic Scholar
Geographical mapping of a multifocal thyroid tumour using genetic alteration analysis & miRNA profiling
Sinéad T. Aherne, P. Smyth, R. Flavin, S. Russell +5 more
2008Molecular Cancer4 citations Open access
Semantic Scholar
for Identifying
Sinéad T. Aherne, A. Tadele
20163 citations
Semantic Scholar
Abstract 1091: miR-125 family of miRNAs mediates prostate cancer cell proliferation and migration
Sinéad T. Aherne, F. O'Neill, S. Madden, M. Clynes +1 more
20162 citations
Semantic Scholar
Geographical mapping of a multifocal thyroid tumor using genetic alteration analysis and miRNA profiling
Sinéad T. Aherne, P. Smyth, R. Flavin, S. Russell +5 more
20082 citations
Semantic Scholar
Abstract 2878: The tumor-permissive role of KHSRP in colorectal cancer: Mechanistic insights from a gene expression study
F. Caiazza, R. Power, K. Killick, D. Higgins +11 more
20161 citations
Semantic Scholar
A gene expression profile indicative of early stage HER2 tyrosine kinase inhibitor response.
F. O'Neill, S. Madden, M. Clynes, P. Doolan +3 more
20131 citations
Semantic Scholar
Gene expression changes as markers of early lapatinib response in a panel of breast cancer cell lines
F. O'Neill, S. Madden, Sinéad T. Aherne, M. Clynes +3 more
2012Molecular Cancer1 citations Open access
Semantic Scholar
Analysis of microRNA let-7a and mir-140 Expression Levels Using Laser Capture Microdissected (LCM) Samples of Thyroid Formalin Fixed Paraffin Embedded (FFPE) Tissues
J. Li, P. Smyth, K. Denning, R. Flavin +4 more
20091 citations
Semantic Scholar
Using Machine Learning Techniques to Predict a Risk Score for New Members of a Chit Fund Group
Sinéad T. Aherne
20180 citations
Semantic Scholar
Su2021 The Tumor-Permissive Role of KHSRP as a Target for the Polyphenol Resveratrol: Potential Tumor-Suppressive Effects in a Pre-Clinical Model of Colorectal Cancer
F. Caiazza, R. Power, K. Killick, D. Higgins +11 more
20160 citations
Semantic Scholar
Abstract P4-07-06: miR-9 expression, retinoids and their potential role in trastuzumab resistance
K. Howe, B. Browne, Sinéad T. Aherne, J. Crown +1 more
20150 citations
Semantic Scholar
738: Circulating miRNAs associated with progression of colorectal cancer
Sinéad T. Aherne, S. Madden, D. Hughes, B. Pardini +6 more
20140 citations
Semantic Scholar
Abstract 1826: Altered expression of miRNAs in acquired trastuzumab resistance
K. Howe, A. Eustace, G. Gullo, B. Browne +3 more
20140 citations
Semantic Scholar
A gene expression profile indicative of early stage HER2 targeted therapy response
F. O'Neill, S. Madden, M. Clynes, J. Crown +3 more
2013Molecular Cancer0 citations Open access
Semantic Scholar
Microrna-9 and -224 In Trastuzumab Resistant HER2 Positive Breast Cancer Cells
K. Howe, A. Eustace, S. Souahli, B. Browne +5 more
20120 citations Open access
Semantic Scholar
143 MicroRNA-224 and −375 in Trastuzumab and Lapatinib Acquired and Innate Resistant HER2 Positive Breast Cancer Cells
K. Howe, A. Eustace, S. Souahli, B. Browne +5 more
20120 citations
Semantic Scholar
442 Gene Expression Changes in Response to a Panel of HER2 Tyrosine Kinase Inhibitors Indicate Potential Markers of Response in Breast Cancer Cell Lines
F. O'Neill, Sinéad T. Aherne, S. Madden, M. Clynes +3 more
20120 citations
Semantic Scholar
Abstract P3-04-12: BreastMark: An integrated approach to mining publically available Transcriptomic Datasets relating to Breast Cancer Outcome
S. Madden, Patricia Gaule, Colin Clarke, Sinéad T. Aherne +4 more
20120 citations
Semantic Scholar
The expression and function of miRNAs in thyroid neoplasia
Sinéad T. Aherne
20100 citations
Semantic Scholar
Gene Expression Profiles in Archival Thyroid Carcinoma Using Pre-amplification RT-PCR, Immunohistochemistry and MicroRNA Expression Analysis
K. Denning, P. Smyth, R. Flavin, S. Finn +6 more
20090 citations
Semantic Scholar
Gene expression profiles in archival thyroid carcinoma using preamplification Q-RT-PCR and immunohistochemistry
K. Denning, P. Smyth, R. Flavin, S. Finn +6 more
20080 citations
Semantic Scholar
Differential microma expression in primary peritoneal serous carcinoma versus ovarian serous
J. O'Leary, P. Smyth, A. Laios, S. O'Toole +10 more
20080 citations
Semantic Scholar
Down-regulation of MIR-195 and MIR-497 from the MicroRNA cluster at chromosome 17p13.1 in papillary serous carcinoma of the peritoneum
R. Flavin, P. Smyth, M. Ring, S. Russell +10 more
20080 citations
Semantic Scholar
MIR-29B expression is associated with disease-free survival in ovarian serous carcinoma patients
R. Flavin, P. Smyth, C. Barrett, S. Russell +16 more
20080 citations
Semantic Scholar
RET/PTC rearrangement in non-thyroid papillary tumors
R. Flavin, G. Jackl, M. Ring, P. Smyth +11 more
20080 citations
Semantic Scholar

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