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J. Lian · SciRah

Researcher profile · Semantic Scholar

J. Lian

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J. Lian — researcher profile on SciRah

h-index: 26
Works: 63
Citations: 7,337

Most-cited papers

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
D. Klionsky, Amal Kamal Abdel-Aziz, Sara Abdelfatah, M. Abdellatif +496 more
2021Autophagy4,016 citations Open access
Semantic Scholar
Editorial :Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). DOI: 10.1080/15548627.2015.1100356;WOS:000373595400001; 2-s2.0-85013763791&;PMID: 26799652
D. Klionsky, K. Abdelmohsen, A. Abe, M. Abedin +496 more
20161,544 citations Open access
Semantic Scholar
Circular RNA vaccine in disease prevention and treatment
Dun Niu, Yaran Wu, J. Lian
2023Signal Transduction and Targeted Therapy251 citations Open access
Semantic Scholar
A natural BH3-mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2—Beclin1 interaction at endoplasmic reticulum
J. Lian, Xiao-Qing Wu, F. He, David Karnak +6 more
2010Cell Death and Differentiation184 citations Open access
Semantic Scholar
The Bcl-2-Beclin 1 interaction in (-)-gossypol-induced autophagy versus apoptosis in prostate cancer cells
J. Lian, David Karnak, Liang Xu
201085 citations Open access
Semantic Scholar
The Bcl-2/xL inhibitor ABT-263 increases the stability of Mcl-1 mRNA and protein in hepatocellular carcinoma cells
Bin Wang, Zhen-Hong Ni, Xu-Fang Dai, Li-Yan Qin +4 more
2014Molecular Cancer80 citations Open access
Semantic Scholar
HCC cells with high levels of Bcl-2 are resistant to ABT-737 via activation of the ROS-JNK-autophagy pathway.
Zhen-Hong Ni, Bin Wang, Xu-Fang Dai, W. Ding +6 more
2014Free Radical Biology & Medicine79 citations
Semantic Scholar
A Smac-mimetic sensitizes prostate cancer cells to TRAIL-induced apoptosis via modulating both IAPs and NF-kappaB
Yao Dai, Mei-Lan Liu, Wenhua Tang, Yongming Li +3 more
2009BMC Cancer75 citations Open access
Semantic Scholar
The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in human hepatocellular cells
P. Cheng, Z. Ni, X. Dai, B. Wang +6 more
2013Cell Death and Disease69 citations Open access
Semantic Scholar
Overcoming chemo/radio-resistance of pancreatic cancer by inhibiting STAT3 signaling
Xiao-Qing Wu, Wenhua Tang, Rebecca T. Marquez, Ke Li +8 more
2016OncoTarget68 citations Open access
Semantic Scholar
Improved performance of students instructed in a hybrid PBL format
J. Lian, F. He
2013Biochemistry and Molecular Biology Education62 citations Open access
Semantic Scholar
Design and synthesis of novel Gefitinib analogues with improved anti-tumor activity
Xiao-Qing Wu, Ming-Dong Li, Yang Qu, Wenhua Tang +4 more
2010Bioorganic & Medicinal Chemistry58 citations Open access
Semantic Scholar
AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells
Zhen-Hong Ni, Jintao He, Yaran Wu, Chang-jiang Hu +11 more
2018Autophagy53 citations Open access
Semantic Scholar
Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356
D. Klionsky, K. Abdelmohsen, A. Abe, J. Abedin +496 more
201650 citations Open access
Semantic Scholar
Targeting the MIR34C-5p-ATG4B-autophagy axis enhances the sensitivity of cervical cancer cells to pirarubicin
Yaran Wu, Zhen-Hong Ni, Xiao-Jing Yan, Xu-Fang Dai +4 more
2016Autophagy45 citations Open access
Semantic Scholar
Sorafenib Sensitizes (−)-Gossypol-Induced Growth Suppression in Androgen-Independent Prostate Cancer Cells via Mcl-1 Inhibition and Bak Activation
J. Lian, Zhen-Hong Ni, Xu-Fang Dai, Chang Su +3 more
2011Molecular Cancer Therapeutics45 citations Open access
Semantic Scholar
HSF1 upregulates ATG4B expression and enhances epirubicin-induced protective autophagy in hepatocellular carcinoma cells.
Nan Zhang, Yaran Wu, Xilin Lyu, Bo Li +9 more
2017Cancer Letters44 citations
Semantic Scholar
The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in human hepatocellular carcinoma cells
P. Cheng, Z. Ni, X. Dai, B. Wang +6 more
2013Cell Death and Disease43 citations Open access
Semantic Scholar
Deacetylation of ATG4B promotes autophagy initiation under starvation
Liangbo Sun, Hao-Jun Xiong, Ling-Xi Chen, Xu-Fang Dai +10 more
2022Science Advances36 citations Open access
Semantic Scholar
Application of flipped classroom combined with virtual simulation platform in clinical biochemistry practical course
Liang-Bo Sun, Dong Liu, J. Lian, Ming-Zhen Yang
2023BMC Medical Education33 citations Open access
Semantic Scholar
Natural Bcl-2 inhibitor (−)– gossypol induces protective autophagy via reactive oxygen species–high mobility group box 1 pathway in Burkitt lymphoma
Zhen-Hong Ni, Xu-Fang Dai, Bin Wang, W. Ding +4 more
2013Leukemia and Lymphoma33 citations
Semantic Scholar
AU4S: A novel synthetic peptide to measure the activity of ATG4 in living cells
Zhen-Hong Ni, Yi Gong, Xu-Fang Dai, W. Ding +7 more
2015Autophagy32 citations Open access
Semantic Scholar
Hsp90 inhibitor 17-AAG sensitizes Bcl-2 inhibitor (-)-gossypol by suppressing ERK-mediated protective autophagy and Mcl-1 accumulation in hepatocellular carcinoma cells.
Bin Wang, Lin-Feng Chen, Zhen-Hong Ni, Xu-Fang Dai +6 more
2014Experimental Cell Research32 citations
Semantic Scholar
LncRNA CRNDE Promotes ATG4B-Mediated Autophagy and Alleviates the Sensitivity of Sorafenib in Hepatocellular Carcinoma Cells
Ling-Xi Chen, Liangbo Sun, Xu-Fang Dai, Tao Li +13 more
2021Frontiers in Cell and Developmental Biology31 citations Open access
Semantic Scholar
KIAA1429 facilitates metastasis via m6A-YTHDC1-dependent RND3 down-regulation in hepatocellular carcinoma cells.
Meihua Shan, Dong Liu, Liang-Bo Sun, Ming-Zhen Yang +12 more
2024Cancer Letters30 citations Open access
Semantic Scholar
Autophagy in the pathogenesis and therapeutic potential of post-traumatic osteoarthritis
Yunquan Gong, Song Li, Jing-Hui Wu, Tongyi Zhang +12 more
2023Burns & Trauma28 citations Open access
Semantic Scholar
Lopinavir enhances anoikis by remodeling autophagy in a circRNA-dependent manner
Yaran Wu, Yang Chen, Xiao-Jing Yan, Xu-Fang Dai +17 more
2024Autophagy23 citations
Semantic Scholar
The downregulation of ATG4B mediated by microRNA-34a/34c-5p suppresses rapamycin-induced autophagy
Yaran Wu, Xu-Fang Dai, Zhen-Hong Ni, Xiao-Jing Yan +2 more
2017Iranian Journal of Basic Medical Sciences22 citations
Semantic Scholar
Activation of AKT/AP1/FoxM1 signaling confers sorafenib resistance to liver cancer cells.
Dongjing Yan, Xiao-Jing Yan, Xu-Fang Dai, Ling-Xi Chen +5 more
2019Oncology Report21 citations Open access
Semantic Scholar
Metformin Synergizes with BCL-XL/BCL-2 Inhibitor ABT-263 to Induce Apoptosis Specifically in p53-Defective Cancer Cells
Xin-zhe Li, Bo Li, Zhen-Hong Ni, Peng Zhou +10 more
2017Molecular Cancer Therapeutics20 citations Open access
Semantic Scholar
Dichloroacetate enhances the anti-tumor effect of sorafenib via modulating the ROS-JNK-Mcl-1 pathway in liver cancer cells.
Liangbo Sun, Yan Jiang, Xiao-Jing Yan, Xu-Fang Dai +13 more
2021Experimental Cell Research17 citations
Semantic Scholar
Identification of an active site on the laminin α4 chain globular domain that binds to αvβ3 integrin and promotes angiogenesis
J. Lian, Xu-Fang Dai, Xiao-Hui Li, F. He
200616 citations Open access
Semantic Scholar
Dihydroergotamine mesylate enhances the anti-tumor effect of sorafenib in liver cancer cells.
Meng He, Qiuyu Liao, Dong Liu, Xu-Fang Dai +11 more
2023Biochemical Pharmacology13 citations
Semantic Scholar
Design, synthesis and in vitro antitumor activity evaluation of novel 4-pyrrylamino quinazoline derivatives
Xiao-Qing Wu, Ming-Dong Li, Wenhua Tang, Youguang Zheng +3 more
2011Chemical Biology and Drug Design13 citations Open access
Semantic Scholar
Deacetylation of ANXA2 by SIRT2 desensitizes hepatocellular carcinoma cells to donafenib via promoting protective autophagy
Liang-Bo Sun, Meng He, Dong Liu, Meihua Shan +13 more
2025Cell Death and Differentiation12 citations
Semantic Scholar
Involvement of acetylation of ATG4B in controlling autophagy induction
Hao-Jun Xiong, Liangbo Sun, J. Lian, F. He
2022Autophagy12 citations Open access
Semantic Scholar
The PPARγ agonist rosiglitazone sensitizes the BH3 mimetic (−)‐gossypol to induce apoptosis in cancer cells with high level of Bcl‐2
Xin-zhe Li, Jintao He, Bo Li, Min Gao +5 more
2018Molecular Carcinogenesis12 citations
Semantic Scholar
Oxyberberine sensitizes liver cancer cells to sorafenib via inhibiting NOTCH1-USP7-c-Myc pathway
Liang-Bo Sun, Meng He, Feng Li, Di Wu +9 more
2024Hepatology Communications9 citations Open access
Semantic Scholar
Inhibition of KIAA1429/HK1 axis enhances the sensitivity of liver cancer cells to sorafenib by regulating the Warburg effect.
Dong Liu, Meihua Shan, Rong Zeng, Meng He +10 more
2024Biochemical Pharmacology9 citations Open access
Semantic Scholar
Identification of an active site on the laminin alpha4 chain globular domain that binds to alphavbeta3 integrin and promotes angiogenesis.
J. Lian, Xu-Fang Dai, Xiao-Hui Li, F. He
2006Biochemical and Biophysical Research Communications - BBRC9 citations
Semantic Scholar
Berberine increases the killing effect of pirarubicin on HCC cells by inhibiting ATG4B-autophagy pathway.
Haiyan He, Meng He, Yun-Xia Wang, Hao-Jun Xiong +10 more
2024Experimental Cell Research7 citations Open access
Semantic Scholar
CircRNA regulates the liquid-liquid phase separation of ATG4B, a novel strategy to inhibit cancer metastasis?
Ziyuan Guo, Yang Chen, Yaran Wu, J. Lian
2024Cell Stress6 citations Open access
Semantic Scholar
CircPHKB decreases the sensitivity of liver cancer cells to sorafenib via miR-1234-3p/CYP2W1 axis.
Ling-Xi Chen, Han-Xi Xiao, Yaran Wu, Dongjing Yan +14 more
2023Genomics5 citations Open access
Semantic Scholar
Cir-DNA Sequencing Revealed the Landscape of Extrachromosomal Circular DNA in Articular Cartilage and the Potential Roles in Osteoarthritis
W. Xiang, Tongyi Zhang, Song Li, Yunquan Gong +10 more
2022bioRxiv3 citations Open access
Semantic Scholar
Dichloroacetate enhances the antitumor effect of pirarubicin via regulating the ROS-JNK signaling pathway in liver cancer cells
Xiao-Jing Yan, P. Xie, Xu-Fang Dai, Ling-Xi Chen +7 more
2020Cancer Drug Resistance3 citations Open access
Semantic Scholar
[Sodium valprovate suppresses autophagy in SH-SY5Y cells via activating miR-34c-5p/ATG4B signaling pathway].
Xu-Fang Dai, Xiao-Jing Yan, Peng Xie, J. Lian
2018Nan fang yi ke da xue xue bao = Journal of Southern Medical University3 citations
Semantic Scholar
(-)-Gossypol enhances the anticancer activity of epirubicin via downregulating survivin in hepatocellular carcinoma.
Wen-Bin Jiang, Wan Wang, Liangbo Sun, Yunhua Xiao +7 more
2022Chemico-Biological Interactions2 citations
Semantic Scholar
"TFEB - HNRNPA2B1": A Positive Feedback Loop Facilitating Metastasis in Hepatocellular Carcinoma cells.
Xiao-Jing Yan, Yaran Wu, Xu-Fang Dai, Huizhong Wen +8 more
2025Experimental Cell Research1 citations
Semantic Scholar
Oxyberberine Enhances the Sensitivity of Liver Cancer Cells to Sorafenib Via Inhibiting NOTCH1-USP7-c-Myc Pathway
Liang-Bo Sun, Meng He, Dong Liu, Meihua Shan +9 more
2023Social Science Research Network1 citations
Semantic Scholar
The Bcl-2/xL inhibitor ABT-263 increases the stability of Mcl-1 mRNA and protein in hepatocellular carcinoma cells
Bin Wang, Zhen-Hong Ni, Xu-Fang Dai, Li-Yan Qin +4 more
2014Molecular Cancer1 citations Open access
Semantic Scholar

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