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M. Lake · SciRah

Researcher profile · Semantic Scholar

M. Lake

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M. Lake — researcher profile on SciRah

h-index: 14
Works: 27
Citations: 836

Most-cited papers

Species differences and molecular determinant of TRPA1 cold sensitivity
Jun Chen, D. Kang, Jing Xu, M. Lake +5 more
2013Nature Communications223 citations Open access
Semantic Scholar
Solution structure and mutational analysis of pituitary adenylate cyclase-activating polypeptide binding to the extracellular domain of PAC1-RS
Chao-Hong Sun, D. Song, Rachel A. Davis-Taber, L. Barrett +9 more
2007Proceedings of the National Academy of Sciences of the United States of America134 citations Open access
Semantic Scholar
Activation of TRPA1 Channels by the Fatty Acid Amide Hydrolase Inhibitor 3′-Carbamoylbiphenyl-3-yl cyclohexylcarbamate (URB597)
Wende Niforatos, Xu-Feng Zhang, M. Lake, K. Walter +6 more
2007Molecular Pharmacology69 citations
Semantic Scholar
An anti-PD-1–GITR-L bispecific agonist induces GITR clustering-mediated T cell activation for cancer immunotherapy
Sarah W. S. Chan, N. Belmar, Sun Ho, B. Rogers +37 more
2022Nature Cancer57 citations Open access
Semantic Scholar
Discovery, structure-activity relationship, and pharmacological evaluation of (5-substituted-pyrrolidinyl-2-carbonyl)-2-cyanopyrrolidines as potent dipeptidyl peptidase IV inhibitors.
Z. Pei, Xiao-Fen Li, K. Longenecker, T. V. von Geldern +22 more
2006Journal of Medicinal Chemistry48 citations Open access
Semantic Scholar
Ligand association rates to the inner-variable-domain of a dual-variable-domain immunoglobulin are significantly impacted by linker design
E. DiGiammarino, J. Harlan, K. Walter, U. Ladror +7 more
2011mAbs42 citations Open access
Semantic Scholar
A Bispecific Molecule Targeting CD40 and Tumor Antigen Mesothelin Enhances Tumor-Specific Immunity
Shiming Ye, D. Cohen, N. Belmar, Donghee Choi +15 more
2019Cancer immunology research41 citations Open access
Semantic Scholar
Utility of Large-Scale Transiently Transfected Cells for Cell-Based High-Throughput Screens to Identify Transient Receptor Potential Channel A1 (TRPA1) Antagonists
Jun Chen, M. Lake, Reza S. Sabet, Wende Niforatos +12 more
2007Journal of biomolecular screening38 citations Open access
Semantic Scholar
Fragment-Based Discovery of an Apolipoprotein E4 (apoE4) Stabilizer.
A. Petros, A. Korepanova, C. Jakob, W. Qiu +17 more
2019Journal of Medicinal Chemistry30 citations Open access
Semantic Scholar
CD40/anti-CD40 antibody complexes which illustrate agonist and antagonist structural switches
M. Argiriadi, L. Benatuil, I. Dubrovska, D. Egan +13 more
2019BMC Molecular and Cell Biology27 citations Open access
Semantic Scholar
Empowering therapeutic antibodies with IFN-α for cancer immunotherapy
Jun Guo, Yu Xiao, R. Iyer, Xin Lu +9 more
2019PLoS ONE25 citations Open access
Semantic Scholar
Cell-Surface Receptor-Ligand Interaction Analysis with Homogeneous Time-Resolved FRET and Metabolic Glycan Engineering: Application to Transmembrane and GPI-Anchored Receptors.
H. Stockmann, V. Todorović, Paul L. Richardson, Violeta L. Marin +6 more
2017Journal of the American Chemical Society19 citations
Semantic Scholar
Expression and purification of human TRPV1 in baculovirus-infected insect cells for structural studies.
A. Korepanova, Ana Pereda-Lopez, L. Solomon, K. Walter +8 more
2009Protein Expression and Purification17 citations
Semantic Scholar
Molecular cloning and characterization of a UDP-glucose-4-epimerase gene (galE) and its expression in pea tissues
M. Lake, C. Williamson, R. D. Slocum
199815 citations
Semantic Scholar
In silico high throughput mutagenesis and screening of signal peptides to mitigate N-terminal heterogeneity of recombinant monoclonal antibodies
Xin Yu, Merlinda Conyne, M. Lake, K. Walter +1 more
2022mAbs13 citations Open access
Semantic Scholar
Activation of TRPA 1 Channels by the Fatty Acid Amide Hydrolase Inhibitor 3-Carbamoylbiphenyl-3-yl cyclohexylcarbamate ( URB 597 )
Wende Niforatos, Xu-Feng Zhang, M. Lake, K. Walter +6 more
200710 citations
Semantic Scholar
Fragment-based discovery of a potent NAMPT inhibitor.
A. Korepanova, K. Longenecker, S. Pratt, S. C. Panchal +6 more
2017Bioorganic & Medicinal Chemistry Letters7 citations Open access
Semantic Scholar
Isolation and characterization of a cDNA encoding a pea ornithine transcarbamoylase (argF) and comparison with other transcarbamoylases
C. Williamson, M. Lake, R. D. Slocum
1996Plant Molecular Biology7 citations
Semantic Scholar
Genome-scale functional genomics screening highlights genes impacting protein fucosylation in Chinese hamster ovary cells.
Kari Barlan, Gaurang P. Bhide, Derek R White, M. Lake +4 more
2023SLAS discovery : advancing life sciences R & D4 citations Open access
Semantic Scholar
Development and validation of an ultra-performance liquid chromatography with tandem mass spectrometry method for determination of soluble repulsive guidance molecule A in human serum and cerebrospinal fluid
P. Schreier, Lili Huang, Emma Fung, J. Mollon +4 more
2024Bioanalysis3 citations Open access
Semantic Scholar
Abstract 2783: Empowering therapeutic monoclonal antibodies with IFN-alpha for cancer immunotherapy
Jun Guo, Yu Xiao, R. Lyer, M. Lake +9 more
2018Immunology2 citations
Semantic Scholar
Development of ELISA to measure TRPV1 protein in rat tissues.
P. Han, A. Korepanova, Melissa Vos, Ana Pereda-Lopez +5 more
2011Journal of Neuroscience Methods2 citations
Semantic Scholar
Application of large-scale transient transfection to cell-based functional assays for ion channels and GPCRs.
Jun Chen, S. Gopalakrishnan, M. Lake, B. Bianchi +2 more
2010Methods in Enzymology2 citations
Semantic Scholar
Heterologous Production of Active Mammalian G‐Protein‐Coupled Receptors Using Baculovirus‐Infected Insect Cells
Mark L. Chiu, B. R. Estvander, T. Esbenshade, S. Kakavas +3 more
20111 citations
Semantic Scholar
Novel method to specifically determine the structures of non-N297 glycans in IgGs.
Gaurang P. Bhide, Natalie E Bohrer, D. Song, J. Cabel +3 more
2023Glycobiology0 citations Open access
Semantic Scholar
Pac1-Rshort N-terminal EC domain Pacap(6-38) complex
E. Olejniczak, Chao-Hong Sun, D. Song, Rachel A. Davis-Taber +9 more
20070 citations
Semantic Scholar
Crystal structure of human dipeptidyl peptidase IV (DPPIV) complexed with cyanopyrrolidine (C5-pro-pro) inhibitor 21ac
K. Longenecker, E. Fry, M. Lake, L. Solomon +2 more
20060 citations
Semantic Scholar

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