Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

S. Gryaznov · SciRah

Researcher profile · Semantic Scholar

S. Gryaznov

Share profile

S. Gryaznov — researcher profile on SciRah

h-index: 41
Works: 135
Citations: 5,183

Most-cited papers

Does a sentinel or a subset of short telomeres determine replicative senescence?
Ying S. Zou, Agnel Sfeir, S. Gryaznov, J. Shay +1 more
2004Molecular Biology of the Cell307 citations Open access
Semantic Scholar
In vivo inhibition of lung cancer by GRN163L: a novel human telomerase inhibitor.
Z. Dikmen, Ginelle C. Gellert, Shalmica R. Jackson, S. Gryaznov +4 more
2005Cancer Research283 citations Open access
Semantic Scholar
A novel telomerase template antagonist (GRN163) as a potential anticancer agent.
A. Asai, Y. Oshima, Yoshihiro Yamamoto, T. Uochi +11 more
2003Cancer Research260 citations
Semantic Scholar
Lipid modification of GRN163, an N3′ → P5′ thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition
B. Herbert, Ginelle C. Gellert, Amelia E Hochreiter, K. Pongracz +6 more
2005Oncogene254 citations
Semantic Scholar
Immunomodulatory spherical nucleic acids
A. Radovic-Moreno, N. Chernyak, Christopher C. Mader, S. Nallagatla +10 more
2015Proceedings of the National Academy of Sciences of the United States of America205 citations Open access
Semantic Scholar
Telomerase antagonists GRN163 and GRN163L inhibit tumor growth and increase chemosensitivity of human hepatoma
M. Djojosubroto, A. Chin, N. Go, S. Schaetzlein +4 more
2005Hepatology154 citations Open access
Semantic Scholar
Telomerase Template Antagonist GRN163L Disrupts Telomere Maintenance, Tumor Growth, and Metastasis of Breast Cancer
Amelia E Hochreiter, Hong-Ling Xiao, Erin M. Goldblatt, S. Gryaznov +4 more
2006Clinical Cancer Research150 citations Open access
Semantic Scholar
New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163.
R. Hashizume, T. Ozawa, S. Gryaznov, A. Bollen +3 more
2008Neuro-Oncology142 citations Open access
Semantic Scholar
Induction of Telomere Dysfunction Mediated By the Telomerase Substrate Precursor 6-Thio-2’-Deoxyguanosine
I. Mender, S. Gryaznov, Z. Dikmen, Woodring E. Wright +1 more
2014Cancer Discovery138 citations Open access
Semantic Scholar
Effects of a novel telomerase inhibitor, GRN163L, in human breast cancer
Ginelle C. Gellert, Z. Dikmen, Woodring E. Wright, S. Gryaznov +1 more
2006Breast Cancer Research and Treatment126 citations
Semantic Scholar
Oligonucleotide N3′→P5′ phosphoramidates as efficient telomerase inhibitors
B. Herbert, K. Pongracz, J. Shay, S. Gryaznov
2002Oncogene121 citations Open access
Semantic Scholar
Telomerase inhibitor GRN163L inhibits myeloma cell growth in vitro and in vivo
M. Shammas, Hemanta Koley, R. Bertheau, P. Neri +10 more
2008Leukemia113 citations Open access
Semantic Scholar
Telomerase Can Inhibit the Recombination-based Pathway of Telomere Maintenance in Human Cells*
L. Ford, Ying S. Zou, K. Pongracz, S. Gryaznov +2 more
2001Journal of Biological Chemistry97 citations Open access
Semantic Scholar
Effects of oligonucleotide N3'-->P5' thio-phosphoramidate (GRN163) targeting telomerase RNA in human multiple myeloma cells.
M. Akiyama, T. Hideshima, M. Shammas, Toshiaki Hayashi +6 more
2003Cancer Research86 citations
Semantic Scholar
Telomerase inhibition with an oligonucleotide telomerase template antagonist: in vitro and in vivo studies in multiple myeloma and lymphoma.
Eunice S. Wang, Kai-Da Wu, A. Chin, S. Chen-Kiang +3 more
2004Blood83 citations Open access
Semantic Scholar
Telomere length assessment in tissue sections by quantitative FISH: Image analysis algorithms
J. O'Sullivan, Jennifer C. Finley, R. Risques, Wen-Tang Shen +5 more
2004Cytometry Part A79 citations Open access
Semantic Scholar
Specific telomere dysfunction induced by GRN163L increases radiation sensitivity in breast cancer cells.
J. Gómez-Millán, Erin M. Goldblatt, S. Gryaznov, M. Mendonca +1 more
2007International Journal of Radiation Oncology, Biology, Physics72 citations
Semantic Scholar
Antiadhesive effects of GRN163L--an oligonucleotide N3'->P5' thio-phosphoramidate targeting telomerase.
Shalmica R. Jackson, Chun-hong Zhu, Vera Paulson, L. Watkins +4 more
2007Cancer Research72 citations Open access
Semantic Scholar
Fast and accurate nonenzymatic copying of an RNA-like synthetic genetic polymer
Shenglong Zhang, J. C. Blain, D. Zielińska, S. Gryaznov +1 more
2013Proceedings of the National Academy of Sciences of the United States of America71 citations Open access
Semantic Scholar
The telomerase template antagonist GRN163L alters MDA-MB-231 breast cancer cell morphology, inhibits growth, and augments the effects of paclitaxel
Erin M. Goldblatt, E. R. Gentry, M. J. Fox, S. Gryaznov +2 more
2009Molecular Cancer Therapeutics68 citations Open access
Semantic Scholar
Telomerase Inhibitors — Oligonucleotide Phosphoramidates as Potential Therapeutic Agents
S. Gryaznov
200164 citations
Semantic Scholar
Interaction of human telomerase with its primer substrate.
G. Wallweber, S. Gryaznov, K. Pongracz, R. Pruzan
2003Biochemistry58 citations
Semantic Scholar
Antitumor effects of specific telomerase inhibitor GRN163 in human glioblastoma xenografts.
T. Ozawa, S. Gryaznov, Lily J. Hu, K. Pongracz +4 more
2004Neuro-Oncology52 citations Open access
Semantic Scholar
Asynchronous replication timing of telomeres at opposite arms of mammalian chromosomes.
Ying S. Zou, S. Gryaznov, J. Shay, W. Wright +1 more
2004Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Anticancer Activity of a Broccoli Derivative, Sulforaphane, in Barrett Adenocarcinoma: Potential Use in Chemoprevention and as Adjuvant in Chemotherapy
A. Qazi, Jagannath Pal, M. Maitah, M. Fulciniti +13 more
201050 citations Open access
Semantic Scholar
Loop–loop interaction of HIV-1 TAR RNA with N3′ → P5′ deoxyphosphoramidate aptamers inhibits in vitro Tat-mediated transcription
F. Darfeuille, A. Arzumanov, S. Gryaznov, M. Gait +2 more
2002Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Anticancer activity of a broccoli derivative, sulforaphane, in barrett adenocarcinoma: potential use in chemoprevention and as adjuvant in chemotherapy.
A. Qazi, Jagannath Pal, M. Maitah, M. Fulciniti +13 more
2010Translational Oncology46 citations Open access
Semantic Scholar
Targeting homologous recombination and telomerase in Barrett’s adenocarcinoma: Impact on telomere maintenance, genomic instability, and tumor growth
R. Lu, Jagannath Pal, Leutz Buon, P. Nanjappa +8 more
2013Oncogene45 citations Open access
Semantic Scholar
Lipid-conjugated telomerase template antagonists sensitize resistant HER2-positive breast cancer cells to trastuzumab
Erin M. Goldblatt, Priscilla Erickson, E. R. Gentry, S. Gryaznov +1 more
2009Breast Cancer Research and Treatment44 citations
Semantic Scholar
Telomere Shortening Sensitizes Cancer Cells to Selected Cytotoxic Agents: In Vitro and In Vivo Studies and Putative Mechanisms
O. Uziel, E. Be'ery, Vladimir Dronichev, Katty Samocha +9 more
2010PLoS ONE43 citations Open access
Semantic Scholar
Telomerase targeted oligonucleotide thio‐phosphoramidates in T24‐luc bladder cancer cells
Z. Dikmen, Woodring E. Wright, J. Shay, S. Gryaznov
2008Journal of Cellular Biochemistry41 citations
Semantic Scholar
Telomere maintenance in laser capture microdissection-purified Barrett's adenocarcinoma cells and effect of telomerase inhibition in vivo
M. Shammas, A. Qazi, R. Batchu, R. Bertheau +13 more
2008Clinical Cancer Research39 citations Open access
Semantic Scholar
Oligonucleotide Conjugate GRN163L Targeting Human Telomerase as Potential Anticancer and Antimetastatic Agent
S. Gryaznov, Shalmica R. Jackson, G. Dikmen, C. Harley +3 more
2007Nucleosides, Nucleotides & Nucleic Acids33 citations
Semantic Scholar
A novel telomerase substrate precursor rapidly induces telomere dysfunction in telomerase positive cancer cells but not telomerase silent normal cells
I. Mender, S. Gryaznov, J. Shay
2015Oncoscience31 citations Open access
Semantic Scholar
Telomerase inhibition improves tumor response to radiotherapy in a murine orthotopic model of human glioblastoma
S. Ferrandon, Céline Malleval, Badia El Hamdani, P. Battiston-Montagne +8 more
2015Molecular Cancer31 citations Open access
Semantic Scholar
Telomerase antagonist imetelstat inhibits esophageal cancer cell growth and increases radiation-induced DNA breaks.
Xuping Wu, Shirin Smavadati, Katarina Nordfjall, K. Karlsson +6 more
2012Biochimica et Biophysica Acta31 citations Open access
Semantic Scholar
Allosteric inhibitors of telomerase: oligonucleotide N3'-->P5' phosphoramidates.
R. Pruzan, K. Pongracz, K. Gietzen, G. Wallweber +1 more
2002Nucleic Acids Research31 citations Open access
Semantic Scholar
A MIR17HG-derived Long Noncoding RNA Provides an Essential Chromatin Scaffold for Protein Interaction and Myeloma Growth.
E. Morelli, M. Fulciniti, M. Samur, C. Ribeiro +29 more
2022Blood29 citations Open access
Semantic Scholar
Imetelstat (a telomerase antagonist) exerts off-target effects on the cytoskeleton
I. Mender, S. Senturk, N. Ozgunes, K. Akcali +5 more
2013International Journal of Oncology28 citations Open access
Semantic Scholar
Oligonucleotide N3′ → P5′ Thio-phosphoramidate Telomerase Template Antagonists as Potential Anticancer Agents
S. Gryaznov, A. Asai, Y. Oshima, Yoshihiro Yamamoto +9 more
2003Nucleosides, Nucleotides & Nucleic Acids26 citations
Semantic Scholar
The Effect of Telomerase Template Antagonist GRN163L on Bone-Marrow-Derived Rat Mesenchymal Stem Cells is Reversible and Associated with Altered Expression of Cyclin d1, cdk4 and cdk6
Zeynep Tokcaer-Keskin, Z. Dikmen, Fatma Ayaloglu-Butun, S. Gültekin +2 more
2010Stem Cell Reviews and Reports25 citations Open access
Semantic Scholar
Synthetic oligonucleotides as RNA mimetics: 2′-modified RNAs and N3′→P5′ phosphoramidates
Martin Egli, S. Gryaznov
2000Cellular and Molecular Life Sciences (CMLS)25 citations Open access
Semantic Scholar
Targeting critical steps of cancer metastasis and recurrence using telomerase template antagonists.
Z. Dikmen, T. Ozgurtas, S. Gryaznov, B. Herbert
2009Biochimica et Biophysica Acta21 citations Open access
Semantic Scholar
In vitro suicide inhibition of self-splicing of a group I intron from Pneumocystis carinii by an N3' --> P5' phosphoramidate hexanucleotide.
S. Testa, S. Gryaznov, D. Turner
1999Proceedings of the National Academy of Sciences of the United States of America19 citations Open access
Semantic Scholar
NUCLEOSIDES, NUCLEOTIDES & NUCLEIC ACIDS, 20(4–7), 441–449 (2001) RNA AND N3′ → P5′ KISSING APTAMERS TARGETED TO THE TRANS-ACTIVATION RESPONSIVE (TAR) RNA OF THE HUMAN IMMUNODEFICIENCY VIRUS-1
F. Darfeuille, C. Cazenave, S. Gryaznov, F. Ducongé +2 more
200317 citations
Semantic Scholar
Telomerase Contributes to Fludarabine Resistance in Primary Human Leukemic Lymphocytes
May Shawi, T. Chu, V. Martínez-Marignac, Y. Yu +6 more
2013PLoS ONE16 citations Open access
Semantic Scholar
Activating an Adaptive Immune Response with a Telomerase-Mediated Telomere Targeting Therapeutic in Hepatocellular Carcinoma
I. Mender, S. Siteni, S. Barron, A. Flusche +13 more
2023Molecular Cancer Therapeutics14 citations Open access
Semantic Scholar
arabino-Fluorooligonucleotide N3′→P5′ phosphoramidates: synthesis and properties
R. Schultz, S. Gryaznov
200012 citations
Semantic Scholar
A Remarkable Stabilization of Complexes Formed by 2,6-Diaminopurine Oligonucleotide N3′→P5′ Phosphoramidates
T. Matray, Soya Gamsey, K. Pongracz, S. Gryaznov
200012 citations
Semantic Scholar
Study of HIV-2 primer-template initiation complex using antisense oligonucleotides.
Florence Boulmé, F. Freund, S. Gryaznov, Peter E. Nielsen +2 more
2000European Journal of Biochemistry12 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

J. Shay×12
Invite
J. Shay — researcher profile on SciRah
K. Pongracz×10
Invite
K. Pongracz — researcher profile on SciRah
Z. Dikmen×8
Invite
Z. Dikmen — researcher profile on SciRah
B. Herbert×8
Invite
B. Herbert — researcher profile on SciRah

×7

Invite

W. Wright — researcher profile on SciRah

Invite

M. Shammas — researcher profile on SciRah

Invite

N. Munshi — researcher profile on SciRah

Invite

A. Chin — researcher profile on SciRah

Invite

C. Harley — researcher profile on SciRah

M. Fulciniti×5

Invite

M. Fulciniti — researcher profile on SciRah

Invite

R. Pruzan — researcher profile on SciRah

Erin M. Goldblatt×4

Invite

Erin M. Goldblatt — researcher profile on SciRah