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A. Butler · SciRah

Researcher profile · Semantic Scholar

A. Butler

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A. Butler — researcher profile on SciRah

h-index: 44
Works: 102
Citations: 11K

Most-cited papers

Normal growth and development in the absence of hepatic insulin-like growth factor I.
S. Yakar, Jun Liu, B. Stannard, A. Butler +3 more
1999Proceedings of the National Academy of Sciences of the United States of America1,460 citations Open access
Semantic Scholar
The somatomedin hypothesis: 2001.
D. LeRoith, C. Bondy, S. Yakar, Jun-Li Liu +1 more
2001Endocrine reviews1,197 citations
Semantic Scholar
Regulation of Circadian Behavior and Metabolism by Synthetic REV-ERB Agonists
Laura A. Solt, Yong-Jun Wang, Subhashish Banerjee, T. Hughes +11 more
2012Nature792 citations Open access
Semantic Scholar
A Unique Metalolic Sysdrone Causes Obesity in the Melanocortin-3 Receptor-Deficient Mouse.
A. Butler, Robert A Kesteson, K. Khong, M. J. Cullen +4 more
2000Endocrinology643 citations Open access
Semantic Scholar
The arcuate nucleus as a conduit for diverse signals relevant to energy homeostasis
R. Cone, M. Cowley, A. Butler, W. Fan +2 more
2001International Journal of Obesity619 citations
Semantic Scholar
Identification of Adropin as a Secreted Factor Linking Dietary Macronutrient Intake with Energy Homeostasis and Lipid Metabolism
K. G. Kumar, J. Trevaskis, D. Lam, Gregory M. Sutton +15 more
2008Cell Metabolism490 citations Open access
Semantic Scholar
Serotonin reciprocally regulates melanocortin neurons to modulate food intake.
L. Heisler, E. Jobst, G. Sutton, Li-Gang Zhou +19 more
2006Neuron409 citations Open access
Semantic Scholar
Control of growth by the somatropic axis: growth hormone and the insulin-like growth factors have related and independent roles.
A. Butler, D. LeRoith
2001Annual Review of Physiology367 citations
Semantic Scholar
Melanocortin-4 receptor is required for acute homeostatic responses to increased dietary fat
A. Butler, D. Marks, W. Fan, Cynthia M. Kuhn +2 more
2001Nature Neuroscience366 citations
Semantic Scholar
Blocking Lactate Export by Inhibiting the Myc Target MCT1 Disables Glycolysis and Glutathione Synthesis
Joanne R. Doherty, Chun-Ying Yang, K. Scott, M. Cameron +18 more
2013Cancer Research362 citations Open access
Semantic Scholar
A Recurring Problem With the Analysis of Energy Expenditure in Genetic Models Expressing Lean and Obese Phenotypes
A. Butler, L. Kozak
2010Diabetes273 citations Open access
Semantic Scholar
Insulin-like growth factor-I receptor signal transduction: at the interface between physiology and cell biology.
A. Butler, S. Yakar, I. Gewolb, Michael Karas +2 more
1998Comparative Biochemistry and Physiology Part B Comparative Biochemistry264 citations Open access
Semantic Scholar
Serotonin 2C Receptor Agonists Improve Type 2 Diabetes via Melanocortin-4 Receptor Signaling Pathways
Li-Gang Zhou, G. Sutton, J. Rochford, R. Semple +10 more
2007Cell Metabolism226 citations Open access
Semantic Scholar
The melanocortin receptors: lessons from knockout models.
A. Butler, R. Cone
2002Neuropeptides224 citations
Semantic Scholar
The melanocortin system and energy balance.
A. Butler
2006Peptides203 citations Open access
Semantic Scholar
What is the role of circulating IGF-I?
D. LeRoith, L. Scavo, A. Butler
2001Trends in endocrinology and metabolism203 citations
Semantic Scholar
Low circulating adropin concentrations with obesity and aging correlate with risk factors for metabolic disease and increase after gastric bypass surgery in humans.
A. Butler, Charmaine S. Tam, K. Stanhope, B. Wolfe +5 more
2012Journal of Clinical Endocrinology and Metabolism200 citations Open access
Semantic Scholar
Therapeutic effects of adropin on glucose tolerance and substrate utilization in diet-induced obese mice with insulin resistance
Su Gao, R. McMillan, Qingzhang Zhu, G. Lopaschuk +2 more
2015Molecular Metabolism186 citations Open access
Semantic Scholar
Diet-genotype interactions in the development of the obese, insulin-resistant phenotype of C57BL/6J mice lacking melanocortin-3 or -4 receptors.
Gregory M. Sutton, J. Trevaskis, M. Hulver, Ryan P. McMillan +4 more
2006Endocrinology161 citations Open access
Semantic Scholar
Differential role of melanocortin receptor subtypes in cachexia.
D. Marks, A. Butler, Renn J. Turner, G. Brookhart +1 more
2003Endocrinology131 citations
Semantic Scholar
The melanocortin-3 receptor is required for entrainment to meal intake
G. Sutton, D. Perez-Tilve, R. Nogueiras, Jidong Fang +5 more
2008Journal of Neuroscience129 citations Open access
Semantic Scholar
Neural melanocortin receptors in obesity and related metabolic disorders
Clémence Girardet, A. Butler
2013Biochimica et Biophysica Acta128 citations Open access
Semantic Scholar
Regulation of Substrate Oxidation Preferences in Muscle by the Peptide Hormone Adropin
Su Gao, R. McMillan, Jordi Jacas, Qingzhang Zhu +8 more
2014Diabetes116 citations Open access
Semantic Scholar
Impaired coordination of nutrient intake and substrate oxidation in melanocortin-4 receptor knockout mice.
D. Albarado, Jennifer W. Mcclaine, J. Stephens, R. Mynatt +4 more
2004Endocrinology110 citations
Semantic Scholar
Melanocortin signaling in the CNS directly regulates circulating cholesterol
D. Perez-Tilve, S. Hofmann, J. Basford, R. Nogueiras +15 more
2010Nature Neuroscience102 citations Open access
Semantic Scholar
Central receptors mediating the cardiovascular actions of melanocyte stimulating hormones
X. Ni, A. Butler, R. Cone, M. Humphreys
2006Journal of Hypertension96 citations
Semantic Scholar
Adropin: An endocrine link between the biological clock and cholesterol homeostasis
Sarbani Ghoshal, Joseph R. Stevens, C. Billon, Clémence Girardet +19 more
2017Molecular Metabolism94 citations Open access
Semantic Scholar
Analysis of the therapeutic functions of novel melanocortin receptor agonists in MC3R- and MC4R-deficient C57BL/6J mice
K. G. Kumar, Gregory M. Sutton, Jesse Z. Dong, P. Roubert +6 more
2009Peptides89 citations Open access
Semantic Scholar
Genetic disruption of gamma-melanocyte-stimulating hormone signaling leads to salt-sensitive hypertension in the mouse.
X. Ni, D. Pearce, A. Butler, R. Cone +1 more
2003Journal of Clinical Investigation81 citations Open access
Semantic Scholar
Protein malnutrition during pregnancy in C57BL/6J mice results in offspring with altered circadian physiology before obesity.
G. Sutton, Armand Centanni, A. Butler
2010Endocrinology78 citations Open access
Semantic Scholar
Stimulation of tumor growth by recombinant human insulin-like growth factor-I (IGF-I) is dependent on the dose and the level of IGF-I receptor expression.
A. Butler, V. Blakesley, M. Tsokos, Vasiliki Pouliki +2 more
1998Cancer Research78 citations
Semantic Scholar
A role for the endogenous opioid beta-endorphin in energy homeostasis.
S. Appleyard, Michael D. Hayward, Juan I. Young, A. Butler +3 more
2003Endocrinology74 citations
Semantic Scholar
Inactivation of PKCθ leads to increased susceptibility to obesity and dietary insulin resistance in mice
Zhanguo Gao, Zhong Q. Wang, Xiao-Ying Zhang, A. Butler +9 more
200766 citations
Semantic Scholar
Low plasma adropin concentrations increase risks of weight gain and metabolic dysregulation in response to a high-sugar diet in male nonhuman primates
A. Butler, Jin-Song Zhang, C. A. Price, Joseph R. Stevens +6 more
2019Journal of Biological Chemistry64 citations Open access
Semantic Scholar
The peptide hormone adropin regulates signal transduction pathways controlling hepatic glucose metabolism in a mouse model of diet-induced obesity
Su Gao, Sarbani Ghoshal, Li-Yan Zhang, Joseph R. Stevens +4 more
2019Journal of Biological Chemistry63 citations Open access
Semantic Scholar
Genetic Dissection of the Functions of the Melanocortin-3 Receptor, a Seven-transmembrane G-protein-coupled Receptor, Suggests Roles for Central and Peripheral Receptors in Energy Homeostasis*
Karima Begriche, P. Levasseur, Jingying Zhang, Jari Rossi +7 more
2011Journal of Biological Chemistry60 citations Open access
Semantic Scholar
Insulin-like growth factors in pediatric health and disease.
D. LeRoith, A. Butler
1999Journal of Clinical Endocrinology and Metabolism59 citations Open access
Semantic Scholar
Hypothalamic malonyl-CoA and the control of food intake
Su Gao, T. Moran, G. Lopaschuk, A. Butler
2013Physiology and Behavior53 citations Open access
Semantic Scholar
Double leptin and melanocortin-4 receptor gene mutations have an additive effect on fat mass and are associated with reduced effects of leptin on weight loss and food intake.
J. Trevaskis, A. Butler
2005Endocrinology52 citations
Semantic Scholar
Central nervous system melanocortin‐3 receptors are required for synchronizing metabolism during entrainment to restricted feeding during the light cycle
Gregory M. Sutton, Karima Begriche, K. G. Kumar, J. Gimble +6 more
2010The FASEB Journal51 citations Open access
Semantic Scholar
Fasting plasma adropin concentrations correlate with fat consumption in human females
M. St-Onge, A. Shechter, J. Shlisky, Charmaine S. Tam +3 more
2013Obesity50 citations Open access
Semantic Scholar
Neurovascular protection by adropin in experimental ischemic stroke through an endothelial nitric oxide synthase-dependent mechanism
Chang-Jun Yang, Bianca P. Lavayen, Lei Liu, Brian D. Sanz +11 more
2021Redox Biology49 citations Open access
Semantic Scholar
Role of Adiponectin and Inflammation in Insulin Resistance of Mc3r and Mc4r Knockout Mice
J. Trevaskis, B. Gawrońska-Kozak, Gregory M. Sutton, M. McNeil +3 more
2007Obesity49 citations Open access
Semantic Scholar
Disproportionate Inhibition of Feeding in Ay Mice by Certain Stressors: A Cautionary Note
José Sérgio Tomaz de Souza, A. Butler, R. Cone
2000Neuroendocrinology48 citations
Semantic Scholar
Melanocortin-3 Receptors and Metabolic Homeostasis
Karima Begriche, Clémence Girardet, P. McDonald, A. Butler
2013Progress in Molecular Biology and Translational Science40 citations Open access
Semantic Scholar
Differential Responses of Plasma Adropin Concentrations To Dietary Glucose or Fructose Consumption In Humans
A. Butler, M. St-Onge, E. Siebert, V. Medici +2 more
2015Scientific Reports36 citations Open access
Semantic Scholar
Biphasic Effect of Melanocortin Agonists on Metabolic Rate and Body Temperature
Beth Lute, William Jou, Dalya M. Lateef, Margalit Goldgof +9 more
2014Cell Metabolism35 citations Open access
Semantic Scholar
Therapeutic benefits of adropin in aged mice after transient ischemic stroke via reduction of blood-brain barrier damage
Chang-Jun Yang, Lei Liu, Bianca P. Lavayen, J. Larochelle +3 more
2022Stroke33 citations
Semantic Scholar
Insulin-like growth factor-I: compartmentalization within the somatotropic axis?
A. Butler, S. Yakar, D. LeRoith
2002News in Physiological Sciences - NIPS33 citations
Semantic Scholar
Doubled lifespan and patient‐like pathologies in progeria mice fed high‐fat diet
R. Kreienkamp, C. Billon, Gonzalo Bedia-Diaz, Carolyn J. Albert +7 more
2018Aging Cell31 citations Open access
Semantic Scholar

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