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T. Burris · SciRah

Researcher profile · Semantic Scholar

T. Burris

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T. Burris — researcher profile on SciRah

h-index: 71
Works: 228
Citations: 16K

Most-cited papers

REV-ERB and ROR nuclear receptors as drug targets
D. Kojetin, T. Burris
2014Nature reviews. Drug discovery543 citations Open access
Semantic Scholar
Rev-erb-α modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy
E. Woldt, Yasmine Sebti, Laura A. Solt, C. Duhem +14 more
2013Nature Medicine434 citations Open access
Semantic Scholar
International Union of Basic and Clinical Pharmacology. XC. Multisite Pharmacology: Recommendations for the Nomenclature of Receptor Allosterism and Allosteric Ligands
A. Christopoulos, J. Changeux, W. Catterall, D. Fabbro +11 more
2014Pharmacological Reviews249 citations Open access
Semantic Scholar
Circadian clock protein Rev-erbα regulates neuroinflammation
Percy Griffin, J. Dimitry, Patrick W. Sheehan, Brian V. Lananna +11 more
2019Proceedings of the National Academy of Sciences of the United States of America233 citations Open access
Semantic Scholar
Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity Of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice
B. Pourcet, Mathilde Zecchin, L. Ferri, Justine Beauchamp +16 more
2017Gastroenterology198 citations Open access
Semantic Scholar
Broad Anti-tumor Activity of a Small Molecule that Selectively Targets the Warburg Effect and Lipogenesis
Colin A. Flaveny, Kristine Griffett, Bahaa Elgendy, M. Kazantzis +7 more
2015Cancer Cell189 citations Open access
Semantic Scholar
An alternate binding site for PPARγ ligands
T. Hughes, P. Giri, Ian Mitchelle S. de Vera, David P. Marciano +7 more
2014Nature Communications182 citations Open access
Semantic Scholar
Pharmacological Targeting of the Mammalian Clock Regulates Sleep Architecture and Emotional Behavior
Subhashish Banerjee, Yong-Jun Wang, Laura A. Solt, Kristine Griffett +8 more
2014Nature Communications127 citations Open access
Semantic Scholar
A liver-selective LXR inverse agonist that suppresses hepatic steatosis.
Kristine Griffett, Laura A. Solt, Bahaa Elgendy, T. Kamenecka +1 more
2013ACS Chemical Biology120 citations
Semantic Scholar
Small Molecule Modulation of Nuclear Receptor Conformational Dynamics: Implications for Function and Drug Discovery
D. Kojetin, T. Burris
2013Molecular Pharmacology118 citations Open access
Semantic Scholar
Disrupting the key circadian regulator CLOCK leads to age-dependent cardiovascular disease.
Faisal J. Alibhai, J. LaMarre, C. J. Reitz, Elena V. Tsimakouridze +7 more
2017Journal of Molecular and Cellular Cardiology110 citations Open access
Semantic Scholar
SR9009 administered for one day after myocardial ischemia-reperfusion prevents heart failure in mice by targeting the cardiac inflammasome
C. J. Reitz, Faisal J. Alibhai, T. Khatua, Mina Rasouli +3 more
2019Communications Biology100 citations Open access
Semantic Scholar
Adropin: An endocrine link between the biological clock and cholesterol homeostasis
Sarbani Ghoshal, Joseph R. Stevens, C. Billon, Clémence Girardet +19 more
2017Molecular Metabolism94 citations Open access
Semantic Scholar
Circadian rhythm-dependent and circadian rhythm-independent impacts of the molecular clock on type 3 innate lymphoid cells
Qianli Wang, M. Robinette, C. Billon, P. Collins +11 more
2019Science immunology85 citations Open access
Semantic Scholar
The nuclear receptor REV-ERBα modulates Th17 cell-mediated autoimmune disease
Christina Chang, Chin-San Loo, Xuan Zhao, Laura A. Solt +11 more
2019Proceedings of the National Academy of Sciences of the United States of America85 citations Open access
Semantic Scholar
The LXR inverse agonist SR9238 suppresses fibrosis in a model of non-alcoholic steatohepatitis
Kristine Griffett, Ryan D. Welch, Colin A. Flaveny, Grant R. Kolar +2 more
2015Molecular Metabolism81 citations Open access
Semantic Scholar
Abstract 545: Suppression of Atherosclerosis by Synthetic REV-ERB Agonist
Sadichha Sitaula, C. Billon, Laura A. Solt, T. Burris
2015Arteriosclerosis, Thrombosis and Vascular Biology79 citations
Semantic Scholar
Involvement of the Clock Gene Rev-erb alpha in the Regulation of Glucagon Secretion in Pancreatic Alpha-Cells
E. Vieira, L. Marroqui, A. Figueroa, B. Merino +5 more
2013PLoS ONE78 citations Open access
Semantic Scholar
REV-ERBα ameliorates heart failure through transcription repression.
Lilei Zhang, Rongli Zhang, Chih-liang Tien, Ricky Chan +7 more
2017JCI Insight71 citations Open access
Semantic Scholar
ROR inverse agonist suppresses insulitis and prevents hyperglycemia in a mouse model of type 1 diabetes.
Laura A. Solt, Subhashish Banerjee, S. Campbell, T. Kamenecka +1 more
2015Endocrinology71 citations Open access
Semantic Scholar
Clock genes, pancreatic function, and diabetes
E. Vieira, T. Burris, I. Quesada
2014Trends in Molecular Medicine70 citations Open access
Semantic Scholar
Anti-Proliferative Actions of a Synthetic REV-ERBα/β Agonist in Breast Cancer Cells
Yong-Jun Wang, D. Kojetin, T. Burris
2015Biochemical Pharmacology65 citations Open access
Semantic Scholar
Restoration of the molecular clock is tumor suppressive in neuroblastoma
Myrthala Moreno-Smith, G. Milazzo, Ling Tao, B. Fekry +14 more
2021Nature Communications47 citations Open access
Semantic Scholar
Recent Advances in the Medicinal Chemistry of Liver X Receptors.
Bahaa Elgendy, Shaimaa S Goher, Lamees Hegazy, M. Arief +1 more
2018Journal of Medicinal Chemistry44 citations Open access
Semantic Scholar
Pharmacological inhibition of REV-ERB stimulates differentiation, inhibits turnover and reduces fibrosis in dystrophic muscle
Ryan D. Welch, C. Billon, Aurore-Cecile Valfort, T. Burris +1 more
2017Scientific Reports43 citations Open access
Semantic Scholar
The mammalian clock and chronopharmacology
Kristine Griffett, T. Burris
2013Bioorganic & Medicinal Chemistry Letters43 citations Open access
Semantic Scholar
Therapeutic Effect of a Synthetic RORα/γ Agonist in an Animal Model of Autism
Yong-Jun Wang, C. Billon, John K. Walker, T. Burris
2015ACS Chemical Neuroscience40 citations Open access
Semantic Scholar
Development of LXR inverse agonists to treat MAFLD, NASH, and other metabolic diseases
Kristine Griffett, T. Burris
2023Frontiers in Medicine39 citations Open access
Semantic Scholar
Rev-erb-alpha modulates skeletal muscle oxidative capacity by regulating mitochondrial biogenesis and autophagy
E. Woldt, Yasmine Sebti, Laura A. Solt, C. Duhem +14 more
201937 citations
Semantic Scholar
Pharmacological Targeting of the Mammalian Clock Reveals a Novel Analgesic for Osteoarthritis-Induced Pain
Vaskar Das, R. Kc, Xin Li, Disha Varma +10 more
2018Gene37 citations Open access
Semantic Scholar
Rev-Erb co-regulates muscle regeneration via tethered interaction with the NF-Y cistrome
Ryan D. Welch, Chun Guo, Monideepa Sengupta, K. J. Carpenter +8 more
2017Molecular Metabolism36 citations Open access
Semantic Scholar
Rev-erb Regulation of Cholesterologenesis
Sadichha Sitaula, Jin-Song Zhang, Fernanda Ruiz, T. Burris
2017Biochemical Pharmacology36 citations Open access
Semantic Scholar
Synthetic ERRα/β/γ Agonist Induces an ERRα-Dependent Acute Aerobic Exercise Response and Enhances Exercise Capacity
C. Billon, Sadichha Sitaula, Subhashish Banerjee, Ryan D. Welch +15 more
2023ACS Chemical Biology33 citations Open access
Semantic Scholar
Artemisia extracts activate PPARγ, promote adipogenesis, and enhance insulin sensitivity in adipose tissue of obese mice
Allison J. Richard, T. Burris, David Sanchez-Infantes, Yong-Jun Wang +2 more
2014Nutrition (Burbank, Los Angeles County, Calif.)32 citations Open access
Semantic Scholar
Structural basis of synthetic agonist activation of the nuclear receptor REV-ERB
Meghan H. Murray, Aurore-Cecile Valfort, Thomas Koelblen, C. Ronin +7 more
2022Nature Communications31 citations Open access
Semantic Scholar
REV-ERB agonism improves liver pathology in a mouse model of NASH
Kristine Griffett, Gonzalo Bedia-Diaz, Bahaa Elgendy, T. Burris
2020bioRxiv31 citations Open access
Semantic Scholar
Doubled lifespan and patient‐like pathologies in progeria mice fed high‐fat diet
R. Kreienkamp, C. Billon, Gonzalo Bedia-Diaz, Carolyn J. Albert +7 more
2018Aging Cell31 citations Open access
Semantic Scholar
Promiscuous activity of the LXR antagonist GSK2033 in a mouse model of fatty liver disease
Kristine Griffett, T. Burris
2016Biochemical and Biophysical Research Communications - BBRC31 citations Open access
Semantic Scholar
Inhibition of RORα/γ suppresses atherosclerosis via inhibition of both cholesterol absorption and inflammation
C. Billon, Sadichha Sitaula, T. Burris
2016Molecular Metabolism30 citations Open access
Semantic Scholar
Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer’s disease
Deborah A. Roby, Fernanda Ruiz, Bailey A Kermath, Jaymie R. Voorhees +6 more
2019PLoS ONE29 citations Open access
Semantic Scholar
Fructose promotes cytoprotection in melanoma tumors and resistance to immunotherapy
Lindsey M. Kuehm, Niloufar Khojandi, A. Piening, Lauryn E Klevorn +12 more
2020Cancer immunology research28 citations Open access
Semantic Scholar
Distinct roles for REV-ERBα and REV-ERBβ in oxidative capacity and mitochondrial biogenesis in skeletal muscle
Ariadna Amador, S. Campbell, M. Kazantzis, Gary Lan +2 more
2018PLoS ONE28 citations Open access
Semantic Scholar
Emerging Role of Nuclear Receptors for the Treatment of NAFLD and NASH
Ryan D. Welch, C. Billon, McKenna Losby, Gonzalo Bedia-Diaz +5 more
2022Metabolites27 citations Open access
Semantic Scholar
Artemisia scoparia Enhances Adipocyte Development and Endocrine Function In Vitro and Enhances Insulin Action In Vivo
Allison J. Richard, S. Fuller, Veaceslav Fedorcenco, R. Beyl +4 more
2014PLoS ONE27 citations Open access
Semantic Scholar
Pharmacological and Genetic Modulation of REV-ERB Activity and Expression Affects Orexigenic Gene Expression
Ariadna Amador, Yong-Jun Wang, Subhashish Banerjee, Theodore M. Kameneka +2 more
2016PLoS ONE26 citations Open access
Semantic Scholar
The Optimal Corepressor Function of Nuclear Receptor Corepressor (NCoR) for Peroxisome Proliferator-activated Receptor γ Requires G Protein Pathway Suppressor 2*
Chun Guo, Yali Li, C. Gow, Madeline Wong +6 more
2014Journal of Biological Chemistry25 citations Open access
Semantic Scholar
A synthesis strategy for tetracyclic terpenoids leads to agonists of ERβ
Wan Shin Kim, Zachary A. Shalit, Sidney Nguyen, Emmalie Schoepke +4 more
2019Nature Communications22 citations Open access
Semantic Scholar
Oral IL-10 suppresses colon carcinogenesis via elimination of pathogenicCD4+ T-cells and induction of antitumor CD8+ T-cell activity
T. Gu, M. De Jesus, H. Gallagher, T. Burris +1 more
2017Oncoimmunology22 citations Open access
Semantic Scholar
Structure of REV-ERBβ Ligand-binding Domain Bound to a Porphyrin Antagonist*
E. Matta-Camacho, Subhashish Banerjee, T. Hughes, Laura A. Solt +3 more
2014Journal of Biological Chemistry22 citations Open access
Semantic Scholar
The Orphan Nuclear Receptor TLX Is a Receptor for Synthetic and Natural Retinoids.
Kristine Griffett, Gonzalo Bedia-Diaz, Lamees Hegazy, Ian Mitchelle S. de Vera +5 more
2020Cell Chemical Biology21 citations Open access
Semantic Scholar

Frequent co-authors

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Laura A. Solt×12
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Laura A. Solt — researcher profile on SciRah
C. Billon×11
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C. Billon — researcher profile on SciRah
Kristine Griffett×10
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Kristine Griffett — researcher profile on SciRah
T. Kamenecka×8
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T. Kamenecka — researcher profile on SciRah

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Yong-Jun Wang — researcher profile on SciRah

Jin-Song Zhang×6

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Jin-Song Zhang — researcher profile on SciRah

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D. Kojetin — researcher profile on SciRah

Subhashish Banerjee×5

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Subhashish Banerjee — researcher profile on SciRah

Sadichha Sitaula×5

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Sadichha Sitaula — researcher profile on SciRah

Ryan D. Welch×5

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Ryan D. Welch — researcher profile on SciRah

Bahaa Elgendy×5

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Bahaa Elgendy — researcher profile on SciRah

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Y. Shin — researcher profile on SciRah