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N. Floquet · SciRah

Researcher profile · Semantic Scholar

N. Floquet

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N. Floquet — researcher profile on SciRah

h-index: 26
Works: 60
Citations: 1,771

Most-cited papers

Elastin as a matrikine.
L. Duca, N. Floquet, A. Alix, B. Haye +1 more
2004Critical reviews in oncology/hematology218 citations
Semantic Scholar
Ligands and signaling proteins govern the conformational landscape explored by a G protein-coupled receptor
Sophie Mary, Marjorie Damian, M. Louet, N. Floquet +4 more
2012Proceedings of the National Academy of Sciences of the United States of America113 citations Open access
Semantic Scholar
Structural and Molecular Determinants of Membrane Binding by the HIV-1 Matrix Protein
Peter Y. Mercredi, Nadine Bucca, Burk W. Loeliger, Christy R Gaines +11 more
2016Journal of Molecular Biology82 citations Open access
Semantic Scholar
Chemical optimization of new ligands of the low-density lipoprotein receptor as potential vectors for central nervous system targeting.
Jean-Daniel M. Malcor, Nadine Payrot, M. David, A. Faucon +9 more
2012Journal of Medicinal Chemistry82 citations
Semantic Scholar
Ghrelin receptor conformational dynamics regulate the transition from a preassembled to an active receptor:Gq complex
Marjorie Damian, Sophie Mary, Mathieu Maingot, Céline M'kadmi +16 more
2015Proceedings of the National Academy of Sciences of the United States of America74 citations Open access
Semantic Scholar
Structural characterization of VGVAPG, an elastin-derived peptide.
N. Floquet, Stéphanie Héry‐Huynh, M. Dauchez, P. Derreumaux +2 more
2004Biopolymers74 citations
Semantic Scholar
The Antitumor Properties of the α3(IV)-(185-203) Peptide from the NC1 Domain of Type IV Collagen (Tumstatin) Are Conformation-dependent*
N. Floquet, S. Pasco, L. Ramont, P. Derreumaux +5 more
2004Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Coarse-grained simulations of the HIV-1 matrix protein anchoring: revisiting its assembly on membrane domains.
Landry Charlier, M. Louet, L. Chaloin, Patrick F. J. Fuchs +4 more
2014Biophysical Journal71 citations Open access
Semantic Scholar
GHSR-D2R heteromerization modulates dopamine signaling through an effect on G protein conformation
Marjorie Damian, V. Pons, P. Renault, Céline M'kadmi +18 more
2018Proceedings of the National Academy of Sciences of the United States of America69 citations Open access
Semantic Scholar
Interaction between the Elastin Peptide VGVAPG and Human Elastin Binding Protein*
Charlotte Blanchevoye, N. Floquet, A. Scandolera, S. Baud +11 more
2012Journal of Biological Chemistry69 citations Open access
Semantic Scholar
Normal mode analysis as a prerequisite for drug design: Application to matrix metalloproteinases inhibitors
N. Floquet, Jean-Didier Maréchal, M. Badet‐Denisot, C. Robert +2 more
2006FEBS Letters68 citations
Semantic Scholar
Structure and dynamics of G protein-coupled receptor–bound ghrelin reveal the critical role of the octanoyl chain
G. Ferré, M. Louet, O. Saurel, Bartholomé Delort +12 more
2019Proceedings of the National Academy of Sciences of the United States of America50 citations Open access
Semantic Scholar
Allosteric modulation of ghrelin receptor signaling by lipids
Marjorie Damian, M. Louet, A. A. Gomes, Céline M'kadmi +8 more
2021Nature Communications45 citations Open access
Semantic Scholar
Collective motions in glucosamine-6-phosphate synthase: influence of ligand binding and role in ammonia channelling and opening of the fructose-6-phosphate binding site.
N. Floquet, P. Durand, B. Maigret, B. Badet +2 more
2009Journal of Molecular Biology44 citations
Semantic Scholar
Human thrombospondin's (TSP-1) C-terminal domain opens to interact with the CD-47 receptor: a molecular modeling study.
N. Floquet, S. Dedieu, L. Martiny, M. Dauchez +1 more
2008Archives of Biochemistry and Biophysics40 citations
Semantic Scholar
Ammonia channeling in bacterial glucosamine‐6‐phosphate synthase (Glms): Molecular dynamics simulations and kinetic studies of protein mutants
N. Floquet, S. Mouilleron, Rasha Daher, B. Maigret +2 more
2007FEBS Letters37 citations
Semantic Scholar
Cryo–electron microscopy structure of the antidiuretic hormone arginine-vasopressin V2 receptor signaling complex
J. Bous, H. Orcel, N. Floquet, C. Leyrat +11 more
2021Science Advances36 citations Open access
Semantic Scholar
Activation of the ghrelin receptor is described by a privileged collective motion: a model for constitutive and agonist-induced activation of a sub-class A G-protein coupled receptor (GPCR).
N. Floquet, Céline M'kadmi, D. Perahia, D. Gagne +6 more
2010Journal of Molecular Biology36 citations
Semantic Scholar
The YSNSG cyclopeptide derived from tumstatin inhibits tumor angiogenesis by down‐regulating endothelial cell migration
J. Thevenard, L. Ramont, J. Devy, B. Brassart +8 more
2009International Journal of Cancer35 citations Open access
Semantic Scholar
Expanding the borononucleotide family: synthesis of borono-analogues of dCMP, dGMP and dAMP.
Anthony R. Martin, K. Mohanan, Delphine Luvino, N. Floquet +3 more
2009Organic and biomolecular chemistry35 citations
Semantic Scholar
The spirocyclopropyl moiety as a methyl surrogate in the structure of l-fucosidase and l-rhamnosidase inhibitors.
Morwenna S. M. Pearson, N. Floquet, C. Bello, P. Vogel +4 more
2009Bioorganic & Medicinal Chemistry34 citations Open access
Semantic Scholar
Dissection of human tropoelastin: solution structure, dynamics and self-assembly of the exon 5 peptide.
B. Bochicchio, N. Floquet, A. Pepe, A. Alix +1 more
2004Chemistry34 citations
Semantic Scholar
Expression and purification of active human internal His(6)-tagged L-glutamine: D-Fructose-6P amidotransferase I.
Céline Richez, J. Boetzel, N. Floquet, K. Koteshwar +3 more
2007Protein Expression and Purification33 citations
Semantic Scholar
Conformational Equilibrium of CDK/Cyclin Complexes by Molecular Dynamics with Excited Normal Modes.
N. Floquet, Maurício G. S. Costa, Paulo R. Batista, P. Renault +5 more
2015Biophysical Journal31 citations Open access
Semantic Scholar
A concerted mechanism for opening the GDP binding pocket and release of the nucleotide in hetero-trimeric G-proteins.
M. Louet, D. Perahia, Jean Martinez, N. Floquet
2011Journal of Molecular Biology30 citations
Semantic Scholar
Identification of TAX2 peptide as a new unpredicted anti-cancer agent
A. Jeanne, E. Sick, J. Devy, N. Floquet +8 more
2015OncoTarget29 citations Open access
Semantic Scholar
Structural and antitumor properties of the YSNSG cyclopeptide derived from tumstatin.
J. Thevenard, N. Floquet, L. Ramont, E. Prost +7 more
2006Chemistry and Biology25 citations Open access
Semantic Scholar
GDP Release Preferentially Occurs on the Phosphate Side in Heterotrimeric G-proteins
M. Louet, Jean Martinez, N. Floquet
2012PLoS Comput. Biol.24 citations Open access
Semantic Scholar
Discovering new inhibitors of bacterial glucosamine-6P synthase (GlmS) by docking simulations.
N. Floquet, Céline Richez, P. Durand, B. Maigret +2 more
2007Bioorganic & Medicinal Chemistry Letters23 citations
Semantic Scholar
Use of Molecular Modeling to Design Selective NTS2 Neurotensin Analogues.
R. Fanelli, N. Floquet, É. Besserer-Offroy, Bartholomé Delort +6 more
2017Journal of Medicinal Chemistry18 citations Open access
Semantic Scholar
The role of aspartyl-rich pentapeptides in comparative complexation of actinide(IV) and iron(III). Part 1
A. Jeanson, C. Berthon, Stéphanie Coantic, C. Den Auwer +11 more
200917 citations
Semantic Scholar
Involvement of tryptophan W276 and of two surrounding amino acid residues in the high constitutive activity of the ghrelin receptor GHS-R1a.
C. Gozé, G. Bergé, Céline M'kadmi, N. Floquet +4 more
2010European Journal of Pharmacology16 citations
Semantic Scholar
Lipids modulate the dynamics of GPCR:β-arrestin interaction
A. Gomes, M. Di Michele, R. A. Roessner, Marjorie Damian +5 more
2024bioRxiv15 citations Open access
Semantic Scholar
Molecular Dynamics Simulations of the Allosteric Modulation of the Adenosine A2a Receptor by a Mini-G Protein
P. Renault, M. Louet, J. Marie, G. Labesse +1 more
2019Scientific Reports14 citations Open access
Semantic Scholar
Sodium is a negative allosteric regulator of the ghrelin receptor.
G. Ferré, A. Gomes, M. Louet, Marjorie Damian +5 more
2023Cell Reports13 citations Open access
Semantic Scholar
Coarse-Grained Prediction of Peptide Binding to G-Protein Coupled Receptors
Bartholomé Delort, P. Renault, Landry Charlier, Florent Raussin +2 more
2017Journal of Chemical Information and Modeling11 citations
Semantic Scholar
Conformational restriction of G‐proteins Coupled Receptors (GPCRs) upon complexation to G‐proteins: A putative activation mode of GPCRs?
M. Louet, Esra Karakaş, Alexandre Perret, D. Perahia +2 more
2013FEBS Letters11 citations
Semantic Scholar
MDexciteR: Enhanced Sampling Molecular Dynamics by Excited Normal Modes or Principal Components Obtained from Experiments.
Maurício G. S. Costa, Paulo R. Batista, A. Gomes, Leonardo S. Bastos +4 more
2023Journal of Chemical Theory and Computation10 citations Open access
Semantic Scholar
Structure and modeling studies of the carboxy-terminus region of human tropoelastin.
N. Floquet, A. Pepe, M. Dauchez, B. Bochicchio +2 more
2005Matrix Biology10 citations
Semantic Scholar
Unveiling G-Protein-Coupled Receptor Conformational Dynamics via Metadynamics Simulations and Markov State Models
R. A. Roessner, N. Floquet, M. Louet
2025bioRxiv8 citations Open access
Semantic Scholar
Concerted conformational dynamics and water movements in the ghrelin G protein-coupled receptor
M. Louet, Marina Casiraghi, Marjorie Damian, Maurício G. S. Costa +14 more
2021eLife6 citations Open access
Semantic Scholar
Synthesis of d- and l-erythro 1,5-dithiopent-1-enopyranoside sulfonium salts and their evaluation as glycosidase inhibitors
M. Buchotte, C. Bello, P. Vogel, N. Floquet +2 more
20094 citations Open access
Semantic Scholar
Dissociation of Membrane-Anchored Heterotrimeric G-Protein Induced by Gα Subunit Binding to GTP
M. Louet, Landry Charlier, Jean Martinez, N. Floquet
2012Journal of Chemical Information and Modeling3 citations
Semantic Scholar
Extended Sampling of Macromolecular Conformations from Uniformly Distributed Points on Multidimensional Normal Mode Hyperspheres
A. A. Gomes, Maurício G. S. Costa, M. Louet, N. Floquet +2 more
2024Journal of Chemical Theory and Computation2 citations Open access
Semantic Scholar
l-Arginine Binding to Human Inducible Nitric Oxide Synthase: An Antisymmetric Funnel Route toward Isoform-Specific Inhibitors?
N. Floquet, Jean-François Hernandez, J. Boucher, Jean Martinez
2011Journal of Chemical Information and Modeling2 citations
Semantic Scholar
Docking Study, Synthesis and SAH-Hydrolase Inhibitory Activity of LAdeninylalanine and Related Analogues
N. Floquet, S. Leroy, M. Muzard, G. Guillerm +1 more
20052 citations
Semantic Scholar
Structure and Dynamics of the Receptor-Bound Ghrelin Lipopeptide
G. Ferré, Marjorie Damian, Céline M'kadmi, O. Saurel +7 more
20181 citations Open access
Semantic Scholar
Diffusion-MF: Approximate Structured Diffusion for Sequence Labelling
N. Floquet, Joseph Le Roux, Nadi Tomeh
20260 citations
Semantic Scholar
Scaling Graph-Based Dependency Parsing with Arc Vectorization and Attention-Based Refinement
N. Floquet, Joseph Le Roux, Nadi Tomeh, Thierry Charnois
2025North American Chapter of the Association for Computational Linguistics0 citations
Semantic Scholar
AVP-V2R-Galphas-beta1-gamma2-Nb35 (L state)
J. Bous, B. Mouillac, P. Bron, S. Granier +2 more
20210 citations
Semantic Scholar

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