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B. Holt · SciRah

Researcher profile · Semantic Scholar

B. Holt

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B. Holt — researcher profile on SciRah

h-index: 39
Works: 98
Citations: 8,102

Most-cited papers

Development of allergen-specific T-cell memory in atopic and normal children.
Susan L. Prescott, C. Macaubas, T. Smallacombe, B. Holt +2 more
1999The Lancet934 citations
Semantic Scholar
The infant airway microbiome in health and disease impacts later asthma development
S. Teo, Danny Mok, K. Pham, M. Kusel +14 more
2015Cell Host and Microbe861 citations Open access
Semantic Scholar
Transplacental priming of the human immune system to environmental allergens: universal skewing of initial T cell responses toward the Th2 cytokine profile.
S. Prescott, C. Macaubas, B. Holt, T. Smallacombe +3 more
1998Journal of Immunology832 citations Open access
Semantic Scholar
Differential Patterns of Methylation of the IFN-γ Promoter at CpG and Non-CpG Sites Underlie Differences in IFN-γ Gene Expression Between Human Neonatal and Adult CD45RO− T Cells1
G. P. White, P. Watt, B. Holt, P. Holt
2002Journal of Immunology335 citations Open access
Semantic Scholar
Genetic ‘risk’ for atopy is associated with delayed postnatal maturation of T‐cell competence
P. Holt, J. B. Clough, B. Holt, M. Baron‐Hay +3 more
1992Clinical and Experimental Allergy275 citations
Semantic Scholar
Association between antenatal cytokine production and the development of atopy and asthma at age 6 years.
C. Macaubas, N. de Klerk, B. Holt, C. Wee +4 more
2003The Lancet260 citations Open access
Semantic Scholar
Development of Interleukin-12-Producing Capacity throughout Childhood
J. Upham, Peter T. Lee, B. Holt, T. Heaton +4 more
2002Infection and Immunity259 citations Open access
Semantic Scholar
An immunoepidemiological approach to asthma: identification of in-vitro T-cell response patterns associated with different wheezing phenotypes in children.
T. Heaton, J. Rowe, S. Turner, R. Aalberse +11 more
2005The Lancet248 citations Open access
Semantic Scholar
Maternal Serum Vitamin D Levels During Pregnancy and Offspring Neurocognitive Development
A. Whitehouse, B. Holt, M. Serralha, P. Holt +2 more
2012Pediatrics246 citations
Semantic Scholar
TH2‐polarized immunological memory to inhalant allergens in atopies is established during infaney and early childhood
A. Yabuhara, C. Macaubas, S. Prescott, T. Venaille +4 more
1997Clinical and Experimental Allergy218 citations
Semantic Scholar
Vitamin D and atopy and asthma phenotypes in children: a longitudinal cohort study
E. Hollams, P. Hart, B. Holt, M. Serralha +5 more
2011European Respiratory Journal210 citations Open access
Semantic Scholar
Association of IL12B promoter polymorphism with severity of atopic and non-atopic asthma in children.
G. Morahan, Dexing Huang, Mark Wu, B. Holt +4 more
2002The Lancet199 citations Open access
Semantic Scholar
Dynamics of airway microbiota identify a critical window for interplay of pathogenic bacteria and allergic sensitization in childhood respiratory disease
S. Teo, H. Tang, Danny Mok, L. Judd +15 more
2018Cell Host and Microbe192 citations Open access
Semantic Scholar
Differential patterns of methylation of the IFN-gamma promoter at CpG and non-CpG sites underlie differences in IFN-gamma gene expression between human neonatal and adult CD45RO- T cells.
G. P. White, P. Watt, B. Holt, P. Holt
2002Journal of Immunology179 citations
Semantic Scholar
Functional Maturation of CD4+CD25+CTLA4+CD45RA+ T Regulatory Cells in Human Neonatal T Cell Responses to Environmental Antigens/Allergens1
C. Thornton, J. Upham, M. Wikström, B. Holt +4 more
2004Journal of Immunology163 citations Open access
Semantic Scholar
A contiguous network of dendritic antigen-presenting cells within the respiratory epithelium.
P. G. Holt, Michael A. Schon-Hegrad, Jane Oliver, B. Holt +1 more
1990International Archives of Allergy and Applied Immunology151 citations
Semantic Scholar
Toward improved prediction of risk for atopy and asthma among preschoolers: a prospective cohort study.
P. Holt, J. Rowe, M. Kusel, Faith Parsons +11 more
2010Journal of Allergy and Clinical Immunology145 citations Open access
Semantic Scholar
Heterogeneity in diphtheria-tetanus-acellular pertussis vaccine-specific cellular immunity during infancy: relationship to variations in the kinetics of postnatal maturation of systemic th1 function.
J. Rowe, C. Macaubas, T. Monger, B. Holt +5 more
2001Journal of Infectious Diseases142 citations Open access
Semantic Scholar
Antigen-Specific Responses to Diphtheria-Tetanus-Acellular Pertussis Vaccine in Human Infants Are Initially Th2 Polarized
J. Rowe, C. Macaubas, T. Monger, B. Holt +4 more
2000Infection and Immunity134 citations Open access
Semantic Scholar
Inhalant allergen‐specific T‐cell reactivity is detectable in close to 100% of atopic and normal individuals: covert responses are unmasked by serum‐free medium
J. Upham, B. Holt, M. J. Baron-Hay, A. Yabuhara +10 more
1995Clinical and Experimental Allergy126 citations Open access
Semantic Scholar
Prenatal versus postnatal sensitization to environmental allergens in a high-risk birth cohort.
J. Rowe, M. Kusel, B. Holt, D. Suriyaarachchi +13 more
2007Journal of Allergy and Clinical Immunology124 citations Open access
Semantic Scholar
Low maternal serum vitamin D during pregnancy and the risk for postpartum depression symptoms
M. Robinson, A. Whitehouse, J. Newnham, S. Gorman +7 more
2014Archives of Women's Mental Health110 citations Open access
Semantic Scholar
CpG methylation patterns in the IFNγ promoter in naive T cells: Variations during Th1 and Th2 differentiation and between atopics and non‐atopics
G. P. White, E. Hollams, S. Yerkovich, A. Bosco +5 more
2006Pediatric Allergy and Immunology108 citations
Semantic Scholar
Maternal Vitamin D Levels and the Autism Phenotype Among Offspring
A. Whitehouse, B. Holt, M. Serralha, P. Holt +2 more
2013Journal of Autism and Developmental Disorders99 citations
Semantic Scholar
T‐cell “priming” against environmental allergens in human neonates: sequential deletion of food antigen reactivity during infancy with concomitant expansion of responses to ubiquitous inhalant allergens
P. Holt, P. O'Keeffe, B. Holt, J. Upham +6 more
1995Pediatric Allergy and Immunology98 citations Open access
Semantic Scholar
Fish oil supplementation in early infancy modulates developing infant immune responses
N. D'Vaz, Suzanne J. Meldrum, J. Dunstan, Tracey F Lee-Pullen +6 more
2012Clinical and Experimental Allergy97 citations
Semantic Scholar
Developing patterns of T cell memory to environmental allergens in the first two years of life.
Susan L. Prescott, C. Macaubas, A. Yabuhara, Thierry J. Venaille +5 more
1997International Archives of Allergy and Immunology94 citations Open access
Semantic Scholar
Vitamin D over the first decade and susceptibility to childhood allergy and asthma
E. Hollams, S. Teo, M. Kusel, B. Holt +7 more
2017Journal of Allergy and Clinical Immunology86 citations Open access
Semantic Scholar
High IFN-γ production by CD8+ T cells and early sensitization among infants at high risk of atopy
J. Rowe, T. Heaton, M. Kusel, D. Suriyaarachchi +5 more
200486 citations
Semantic Scholar
Elucidation of asthma phenotypes in atopic teenagers through parallel immunophenotypic and clinical profiling.
E. Hollams, M. Deverell, M. Serralha, D. Suriyaarachchi +10 more
2009Journal of Allergy and Clinical Immunology76 citations Open access
Semantic Scholar
Th2-associated immunity to bacteria in teenagers and susceptibility to asthma
E. Hollams, B. Hales, Claus Bachert, W. Huvenne +8 more
2010European Respiratory Journal74 citations Open access
Semantic Scholar
Development of immunologic memory against tetanus toxoid and pertactin antigens from the diphtheria-tetanus-pertussis vaccine in atopic versus nonatopic children.
P. Holt, A. Rudin, C. Macaubas, B. Holt +3 more
2000Journal of Allergy and Clinical Immunology66 citations Open access
Semantic Scholar
Distinguishing benign from pathologic TH2 immunity in atopic children.
P. Holt, D. Strickland, A. Bosco, D. Belgrave +8 more
2016Journal of Allergy and Clinical Immunology64 citations Open access
Semantic Scholar
Genome-wide association study of vitamin D levels in children: replication in the Western Australian Pregnancy Cohort (Raine) study
D. Anderson, B. Holt, C. Pennell, P. Holt +2 more
2014Genes and Immunity49 citations
Semantic Scholar
Regulation of T-cell sensitization at epithelial surfaces in the respiratory tract: suppression of IgE responses to inhaled antigens by CD3+ Tcr alpha-/beta- lymphocytes (putative gamma/delta T cells).
C. Mcmenamin, J. Oliver, B. Girn, B. Holt +3 more
1991Immunology48 citations
Semantic Scholar
In vitro synthesis of IgE by human peripheral blood leucocytes. III. Release of pre-formed antibody.
K. J. Turner, Patrick G. Holt, B. Holt, K. Cameron
1983Clinical and Experimental Immunology44 citations
Semantic Scholar
Primary prevention of severe lower respiratory illnesses in at-risk infants using the immunomodulator OM85.
P. Sly, Sally Galbraith, Zahir Islam, B. Holt +2 more
2019Journal of Allergy and Clinical Immunology43 citations Open access
Semantic Scholar
Allergen recognition in the origin of asthma.
P. Holt, A. Yabuhara, Susan L. Prescott, T. Venaille +4 more
1997Ciba Foundation symposium40 citations Open access
Semantic Scholar
Developmental regulation of type 1 and type 3 interferon production and risk for infant infections and asthma development
P. Holt, Danny Mok, Debasis Panda, Lynnsey A. Renn +8 more
2019Journal of Allergy and Clinical Immunology39 citations Open access
Semantic Scholar
Allergen‐induced cytokine secretion in relation to atopic symptoms and immunoglobulin E and immunoglobulin G subclass antibody responses
M. Jenmalm, B. Björkstén, C. Macaubas, B. Holt +2 more
1999Pediatric Allergy and Immunology38 citations
Semantic Scholar
Primary sensitization to inhalant allergens.
C. Macaubas, S. Prescott, T. Venaille, B. Holt +3 more
2000Pediatric Allergy and Immunology37 citations Open access
Semantic Scholar
High IFN-gamma production by CD8+ T cells and early sensitization among infants at high risk of atopy.
J. Rowe, T. Heaton, M. Kusel, D. Suriyaarachchi +5 more
2004Journal of Allergy and Clinical Immunology36 citations
Semantic Scholar
Immunoregulation of asthma: control of T-lymphocyte activation in the respiratory tract.
Patrick G. Holt, C. Mcmenamin, M. Schon-Hegrad, D. Strickland +6 more
1991The European respiratory journal. Supplement36 citations
Semantic Scholar
Personalized Transcriptomics Reveals Heterogeneous Immunophenotypes in Children with Viral Bronchiolitis.
A. Jones, D. Anderson, Sally Galbraith, E. Fantino +8 more
2019American Journal of Respiratory and Critical Care Medicine33 citations Open access
Semantic Scholar
Reciprocal patterns of allergen‐induced GATA‐3 expression in peripheral blood mononuclear cells from atopics vs. non‐atopics
C. Macaubas, Peter T. Lee, T. B. Smallacombe, B. Holt +3 more
2002Clinical and Experimental Allergy33 citations Open access
Semantic Scholar
Low‐level exposure to house dust mites stimulates T‐cell responses during early childhood independent of atopy
B. Björkstén, B. Holt, M. Baron‐Hay, A. K. Munir +1 more
1996Clinical and Experimental Allergy32 citations
Semantic Scholar
Neonatal genetics of gene expression reveal potential origins of autoimmune and allergic disease risk
Qin-Qin Huang, H. Tang, S. Teo, Danny Mok +11 more
2020Nature Communications31 citations Open access
Semantic Scholar
Early‐onset atopy is associated with enhanced lymphocyte cytokine responses in 11‐year‐old children
S. Turner, T. Heaton, J. Rowe, D. Suriyaarachchi +8 more
2007Clinical and Experimental Allergy31 citations
Semantic Scholar
“Bystander” amplification of PBMC cytokine responses to seasonal allergen in polysensitized atopic children
A. Rudin, C. Macaubas, C. Wee, B. Holt +2 more
2001Allergy. European Journal of Allergy and Clinical Immunology28 citations Open access
Semantic Scholar
Cord blood hemopoietic progenitor profiles predict acute respiratory symptoms in infancy
R. Fernandes, M. Kusel, M. Cyr, R. Sehmi +7 more
2008Pediatric Allergy and Immunology23 citations Open access
Semantic Scholar

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E. Hollams — researcher profile on SciRah

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N. de Klerk — researcher profile on SciRah

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J. Rowe — researcher profile on SciRah

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