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R. Guler · SciRah

Researcher profile · Semantic Scholar

R. Guler

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R. Guler — researcher profile on SciRah

h-index: 34
Works: 99
Citations: 5,735

Most-cited papers

A promoter-level mammalian expression atlas
A. Forrest, H. Kawaji, M. Rehli, J. Baillie +256 more
2014Nature1,977 citations Open access
Semantic Scholar
Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells
E. Arner, Carsten O. Daub, K. Vitting-Seerup, Robin Andersson +105 more
2015Science588 citations Open access
Semantic Scholar
Statin therapy reduces the mycobacterium tuberculosis burden in human macrophages and in mice by enhancing autophagy and phagosome maturation.
Suraj P. Parihar, R. Guler, R. Khutlang, Dirk M. Lang +5 more
2014Journal of Infectious Diseases287 citations
Semantic Scholar
Syk Kinase-Coupled C-type Lectin Receptors Engage Protein Kinase C-δ to Elicit Card9 Adaptor-Mediated Innate Immunity
D. Strasser, K. Neumann, Hanna Bergmann, M. Marakalala +9 more
2012Immunity274 citations Open access
Semantic Scholar
Functional annotation of human long noncoding RNAs via molecular phenotyping
Jordan A. Ramilowski, Chi-Wai Yip, Saumya Agrawal, Jen-Chien Chang +112 more
2019bioRxiv150 citations Open access
Semantic Scholar
Statins: a viable candidate for host-directed therapy against infectious diseases
Suraj P. Parihar, R. Guler, F. Brombacher
2018Nature reviews. Immunology137 citations
Semantic Scholar
Transmembrane TNF Induces an Efficient Cell-Mediated Immunity and Resistance to Mycobacterium bovis Bacillus Calmette-Guérin Infection in the Absence of Secreted TNF and Lymphotoxin-α1
Maria L. Olleros, R. Guler, N. Corazza, D. Vesin +5 more
2002Journal of Immunology126 citations Open access
Semantic Scholar
FANTOM5 CAGE profiles of human and mouse samples
Shuhei Noguchi, T. Arakawa, S. Fukuda, M. Furuno +174 more
2017Scientific Data119 citations Open access
Semantic Scholar
The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase
Lisa M. Graham, Vandana Gupta, Georgia Schafer, Delyth M. Reid +11 more
2012Journal of Biological Chemistry116 citations Open access
Semantic Scholar
A Virus-Like Particle-Based Vaccine Selectively Targeting Soluble TNF-α Protects from Arthritis without Inducing Reactivation of Latent Tuberculosis
G. Spohn, R. Guler, P. Johansen, Iris Keller +9 more
2007Journal of Immunology113 citations Open access
Semantic Scholar
Batf2/Irf1 Induces Inflammatory Responses in Classically Activated Macrophages, Lipopolysaccharides, and Mycobacterial Infection
Sugata Roy, R. Guler, Suraj P. Parihar, S. Schmeier +12 more
2015Journal of Immunology102 citations Open access
Semantic Scholar
Contribution of transmembrane tumor necrosis factor to host defense against Mycobacterium bovis bacillus Calmette-guerin and Mycobacterium tuberculosis infections.
Maria L. Olleros, R. Guler, D. Vesin, R. Parapanov +6 more
2005American Journal of Pathology98 citations Open access
Semantic Scholar
Transcriptional landscape of Mycobacterium tuberculosis infection in macrophages
Sugata Roy, S. Schmeier, B. Kaczkowski, E. Arner +14 more
2018Scientific Reports87 citations Open access
Semantic Scholar
Lethal Mycobacterium Bovis Bacillus Calmette Guérin Infection in Nitric Oxide Synthase 2-Deficient Mice: Cell-Mediated Immunity Requires Nitric Oxide Synthase 2
I. Garcia, R. Guler, D. Vesin, Maria L. Olleros +4 more
2000Laboratory Investigation84 citations Open access
Semantic Scholar
The Role of Scavenger Receptor B1 in Infection with Mycobacterium tuberculosis in a Murine Model
Georgia Schäfer, R. Guler, G. Murray, F. Brombacher +1 more
2009PLoS ONE71 citations Open access
Semantic Scholar
The gut microbiome in tuberculosis susceptibility and treatment response: guilty or not guilty?
O. Eribo, N. du Plessis, M. Ozturk, R. Guler +2 more
2019Cellular and Molecular Life Sciences69 citations Open access
Semantic Scholar
Differential effects of TNF and LTα in the host defense against M. bovis BCG
M. Bopst, I. Garcia, R. Guler, Maria L. Olleros +6 more
2001European Journal of Immunology66 citations Open access
Semantic Scholar
Blocking IL-1α but not IL-1β increases susceptibility to chronic Mycobacterium tuberculosis infection in mice.
R. Guler, Suraj P. Parihar, G. Spohn, P. Johansen +2 more
2011Vaccine65 citations Open access
Semantic Scholar
Redefining the transcriptional regulatory dynamics of classically and alternatively activated macrophages by deepCAGE transcriptomics
Sugata Roy, S. Schmeier, E. Arner, T. Alam +15 more
2015Nucleic Acids Research62 citations Open access
Semantic Scholar
SHREC ’ 15 Track : Non-rigid 3 D Shape Retrieval †
Zhou-Hui Lian, Jin-Bo Zhang, Sung-Bin Choi, Hanan ElNaghy +22 more
201660 citations
Semantic Scholar
Inhibition of inducible nitric oxide synthase protects against liver injury induced by mycobacterial infection and endotoxins.
R. Guler, Maria L. Olleros, D. Vesin, R. Parapanov +8 more
2004Journal of Hepatology59 citations Open access
Semantic Scholar
Both the Fas Ligand and Inducible Nitric Oxide Synthase Are Needed for Control of Parasite Replication within Lesions in Mice Infected with Leishmania major whereas the Contribution of Tumor Necrosis Factor Is Minimal
R. Chakour, R. Guler, Mélanie Bugnon, C. Allenbach +4 more
2003Infection and Immunity53 citations Open access
Semantic Scholar
The Syk/CARD9-coupled receptor Dectin-1 is not required for host resistance to Mycobacterium tuberculosis in mice
M. Marakalala, R. Guler, Lungile Matika, G. Murray +5 more
2011Microbes and infection48 citations Open access
Semantic Scholar
A role for lymphotoxin β receptor in host defense against Mycobacterium bovis BCG infection
R. Lucas, F. Tacchini-Cottier, R. Guler, D. Vesin +6 more
1999European Journal of Immunology48 citations Open access
Semantic Scholar
Preclinical efficacy and safety of an anti-IL-1β vaccine for the treatment of type 2 diabetes
G. Spohn, C. Schori, Iris Keller, Katja Sladko +6 more
2014Molecular Therapy: Methods & Clinical Development47 citations Open access
Semantic Scholar
Simvastatin Enhances Protection against Listeria monocytogenes Infection in Mice by Counteracting Listeria-Induced Phagosomal Escape
Suraj P. Parihar, R. Guler, Dirk M. Lang, Harukazu Suzuki +2 more
2013PLoS ONE47 citations Open access
Semantic Scholar
Targeting Batf2 for infectious diseases and cancer
R. Guler, Sugata Roy, Harukazu Suzuki, F. Brombacher
2015OncoTarget46 citations Open access
Semantic Scholar
Targeting Molecular Inflammatory Pathways in Granuloma as Host-Directed Therapies for Tuberculosis
R. Guler, M. Ozturk, Solima Sabeel, Bongani Motaung +3 more
2021Frontiers in Immunology44 citations Open access
Semantic Scholar
Protein kinase C δ is essential for optimal macrophage-mediated phagosomal containment of Listeria monocytogenes
Anita Schwegmann, R. Guler, Antony J. Cutler, B. Arendse +8 more
2007Proceedings of the National Academy of Sciences of the United States of America44 citations Open access
Semantic Scholar
Topical Simvastatin as Host-Directed Therapy against Severity of Cutaneous Leishmaniasis in Mice
Suraj P. Parihar, Mary-Anne Hartley, R. Hurdayal, R. Guler +1 more
2016Scientific Reports43 citations Open access
Semantic Scholar
Host-directed drug therapy for tuberculosis.
R. Guler, F. Brombacher
2015Nature Chemical Biology42 citations
Semantic Scholar
Impact of statins as immune-modulatory agents on inflammatory markers in adults with chronic diseases: A systematic review and meta-analysis
Solima Sabeel, Bongani Motaung, K. Nguyen, M. Ozturk +11 more
2025PLoS ONE40 citations Open access
Semantic Scholar
Protein kinase C-delta (PKCδ), a marker of inflammation and tuberculosis disease progression in humans, is important for optimal macrophage killing effector functions and survival in mice
S. Parihar, M. Ozturk, M. Marakalala, D. Loots +11 more
2017Mucosal Immunology40 citations Open access
Semantic Scholar
Differential Targeting of c-Maf, Bach-1, and Elmo-1 by microRNA-143 and microRNA-365 Promotes the Intracellular Growth of Mycobacterium tuberculosis in Alternatively IL-4/IL-13 Activated Macrophages
O. Tamgue, L. Gcanga, M. Ozturk, Lauren Whitehead +10 more
2019Frontiers in Immunology34 citations Open access
Semantic Scholar
Differential Effects of Total and Partial Neutralization of Tumor Necrosis Factor on Cell-Mediated Immunity to Mycobacterium bovis BCG Infection
R. Guler, Maria L. Olleros, D. Vesin, R. Parapanov +1 more
2005Infection and Immunity31 citations Open access
Semantic Scholar
Batf2 differentially regulates tissue immunopathology in Type 1 and Type 2 diseases
R. Guler, T. Mpotje, M. Ozturk, J. K. Nono +12 more
2018Mucosal Immunology27 citations Open access
Semantic Scholar
IL-4Rα-Dependent Alternative Activation of Macrophages Is Not Decisive for Mycobacterium tuberculosis Pathology and Bacterial Burden in Mice
R. Guler, Suraj P. Parihar, Suzana Savvi, E. Logan +7 more
2015PLoS ONE27 citations Open access
Semantic Scholar
Genome-wide profiling of transcribed enhancers during macrophage activation
E. Denisenko, R. Guler, M. Mhlanga, Harukazu Suzuki +2 more
2017Epigenetics & Chromatin26 citations Open access
Semantic Scholar
Evaluation of Berberine as an Adjunct to TB Treatment
M. Ozturk, J. E. Chia, Rudranil Hazra, M. Saqib +6 more
2021Frontiers in Immunology25 citations Open access
Semantic Scholar
PKCδ regulates IL‐12p40/p70 production by macrophages and dendritic cells, driving a type 1 healer phenotype in cutaneous leishmaniasis
R. Guler, M. Afshar, B. Arendse, Suraj P. Parihar +4 more
2011European Journal of Immunology25 citations Open access
Semantic Scholar
Transcriptionally induced enhancers in the macrophage immune response to Mycobacterium tuberculosis infection
E. Denisenko, R. Guler, M. Mhlanga, Harukazu Suzuki +2 more
2018BMC Genomics24 citations Open access
Semantic Scholar
CD28 and IL-4: two heavyweights controlling the balance between immunity and inflammation
T. Hünig, F. Lühder, Karin Elflein, T. Gogishvili +4 more
2010Medical Microbiology and Immmunology24 citations Open access
Semantic Scholar
Limited Role for Lymphotoxin α in the Host Immune Response to Mycobacterium tuberculosis
N. Allie, R. Keeton, Nathalie Court, B. Abel +11 more
2010Journal of Immunology23 citations Open access
Semantic Scholar
Evaluation of minor groove binders (MGBs) as novel anti-mycobacterial agents and the effect of using non-ionic surfactant vesicles as a delivery system to improve their efficacy
Lerato Hlaka, Michael-Jon Rosslee, M. Ozturk, Santosh Kumar +7 more
2017Journal of Antimicrobial Chemotherapy21 citations Open access
Semantic Scholar
An evaluation of Minor Groove Binders as anti-fungal and anti-mycobacterial therapeutics.
Fraser J. Scott, R. J. Nichol, A. Khalaf, Federica Giordani +13 more
2017European journal of medicinal chemistry21 citations Open access
Semantic Scholar
Antisense Therapy for Infectious Diseases
Lwanda Abonga Buthelezi, S. Pillay, Noxolo N. Ntuli, L. Gcanga +1 more
2023Cells20 citations Open access
Semantic Scholar
Toward Preparing a Knowledge Base to Explore Potential Drugs and Biomedical Entities Related to COVID-19: Automated Computational Approach
Junaed Younus Khan, Md. Tawkat Islam Khondaker, Iram Tazim Hoque, Hamada R. H. Al-Absi +4 more
2020JMIR Medical Informatics19 citations Open access
Semantic Scholar
Circulating concentrations of interleukin‐18, interleukin‐18 binding protein, and γ interferon in patients with alcoholic hepatitis
L. Spahr, I. Garcia, S. Bresson-Hadni, L. Rubbia-Brandt +4 more
2004Liver international (Print)18 citations Open access
Semantic Scholar
Host-directed targeting of lincRNA-MIR99AHG suppresses intracellular growth of Mycobacterium tuberculosis
L. Gcanga, O. Tamgue, M. Ozturk, S. Pillay +11 more
2020Nucleic Acid Therapeutics16 citations Open access
Semantic Scholar
COVID-19Base v3: Update of the knowledgebase for drugs and biomedical entities linked to COVID-19
Syed Abdullah Basit, Rizwan Qureshi, Saleh Musleh, R. Guler +3 more
2023Frontiers in Public Health15 citations Open access
Semantic Scholar

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E. Arner — researcher profile on SciRah