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O. Brand · SciRah

Researcher profile · Semantic Scholar

O. Brand

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O. Brand — researcher profile on SciRah

h-index: 26
Works: 63
Citations: 3,243

Most-cited papers

Genome-wide association study of copy number variation in 16,000 cases of eight common diseases and 3,000 shared controls
Nick Craddock, M. Hurles, Niall J. Cardin, R. Pearson +213 more
2010Nature706 citations Open access
Semantic Scholar
Negligible impact of rare autoimmune-locus coding-region variants on missing heritability
K. Hunt, Vanisha Mistry, N. Bockett, T. Ahmad +33 more
2013Nature211 citations Open access
Semantic Scholar
Association of the TSHR gene with Graves' disease: the first disease specific locus
B. DeChairo, D. Zabaneh, J. Collins, O. Brand +14 more
2005European Journal of Human Genetics174 citations
Semantic Scholar
Association of the interleukin‐2 receptor alpha (IL‐2Rα)/CD25 gene region with Graves’ disease using a multilocus test and tag SNPs
O. Brand, C. Lowe, J. Heward, J. Franklyn +3 more
2007Clinical Endocrinology173 citations
Semantic Scholar
Seven newly identified loci for autoimmune thyroid disease
J. Cooper, M. Simmonds, N. Walker, O. Burren +8 more
2012Human Molecular Genetics156 citations Open access
Semantic Scholar
Association scan of 14,500 nonsynonymous SNPs in four diseases identifies autoimmunity variants
P. Burton, David G. Clayton, L. Cardon, Nick Craddock +211 more
2007Nature Genetics156 citations Open access
Semantic Scholar
Alterations in T and B cell function persist in convalescent COVID-19 patients
H. Shuwa, T. Shaw, S. Knight, Kelly Wemyss +78 more
2021i Medicina145 citations Open access
Semantic Scholar
Association of the thyroid stimulating hormone receptor gene (TSHR) with Graves' disease.
O. Brand, J. Barrett, M. Simmonds, P. Newby +14 more
2009Human Molecular Genetics141 citations Open access
Semantic Scholar
Defective lung function following influenza virus is due to prolonged, reversible hyaluronan synthesis
T. Bell, O. Brand, D. Morgan, S. Salek-Ardakani +9 more
2019Matrix Biology120 citations Open access
Semantic Scholar
HLA, CTLA-4 and PTPN22: the shared genetic master-key to autoimmunity?
O. Brand, S. Gough, J. Heward
2005Expert Reviews in Molecular Medicine117 citations
Semantic Scholar
Association of PTPN22 haplotypes with Graves' disease.
J. Heward, O. Brand, J. Barrett, J. Carr-Smith +2 more
2007Journal of Clinical Endocrinology and Metabolism108 citations
Semantic Scholar
Selective Targeting of TGF-β Activation to Treat Fibroinflammatory Airway Disease
S. Minagawa, Jianlong Lou, Robert I Seed, A. Cormier +28 more
2014Science Translational Medicine92 citations Open access
Semantic Scholar
Comparative performances of machine learning methods for classifying Crohn Disease patients using genome-wide genotyping data
A. Romagnoni, S. Jégou, K. van Steen, G. Wainrib +341 more
2019Scientific Reports88 citations Open access
Semantic Scholar
Skewed X chromosome inactivation and female preponderance in autoimmune thyroid disease: an association study and meta-analysis.
M. Simmonds, F. Kavvoura, O. Brand, P. Newby +4 more
2014Journal of Clinical Endocrinology and Metabolism78 citations Open access
Semantic Scholar
Association of caveolin-1 gene polymorphism with kidney transplant fibrosis and allograft failure.
Jason H. Moore, A. McKnight, M. Simmonds, A. Courtney +9 more
2010Journal of the American Medical Association (JAMA)78 citations Open access
Semantic Scholar
Donor ABCB1 variant associates with increased risk for kidney allograft failure.
Jason H. Moore, A. McKnight, B. Döhler, M. Simmonds +10 more
2012Journal of the American Society of Nephrology76 citations Open access
Semantic Scholar
Tag SNP screening of the PDCD1 gene for association with Graves’ disease
P. Newby, Emma Roberts-Davies, O. Brand, J. Heward +3 more
2007Clinical Endocrinology54 citations
Semantic Scholar
Interplay between EZH2 and G9a Regulates CXCL10 Gene Repression in Idiopathic Pulmonary Fibrosis
William R. Coward, O. Brand, A. Pasini, G. Jenkins +2 more
2017American Journal of Respiratory Cell and Molecular Biology48 citations Open access
Semantic Scholar
Rare and functional SIAE variants are not associated with autoimmune disease risk in up to 66,924 individuals of European ancestry
K. Hunt, D. Smyth, Tobias C. Balschun, M. Ban +61 more
2011Nature Genetics48 citations Open access
Semantic Scholar
Thyroid Stimulating Hormone Receptor (TSHR) Intron 1 Variants Are Major Risk Factors for Graves' Disease in Three European Caucasian Cohorts
R. Płoski, O. Brand, B. Jurecka-Lubieniecka, M. Franaszczyk +8 more
2010PLoS ONE48 citations Open access
Semantic Scholar
Innate Immune Cell Suppression and the Link With Secondary Lung Bacterial Pneumonia
D. Morgan, J. Casulli, C. Chew, E. Connolly +5 more
2018Frontiers in Immunology44 citations Open access
Semantic Scholar
Monocyte migration profiles define disease severity in acute COVID-19 and unique features of long COVID
N. Scott, L. Pearmain, S. Knight, O. Brand +33 more
2023European Respiratory Journal43 citations Open access
Semantic Scholar
Transforming Growth Factor- and Interleukin-1 Signaling Pathways Converge on the Chemokine CCL20 Promoter*
O. Brand, Sangeeta Somanath, C. Moermans, Haruhiko Yanagisawa +11 more
201532 citations
Semantic Scholar
Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation
A. Pasini, O. Brand, G. Jenkins, A. Knox +1 more
2018Biochimica et Biophysica Acta. Gene Regulatory Mechanisms29 citations Open access
Semantic Scholar
Association of Fc receptor like 5 (FCRL5) with Graves’ disease is secondary to the effect of FCRL3
M. Simmonds, O. Brand, J. Barrett, P. Newby +2 more
2010Clinical Endocrinology28 citations Open access
Semantic Scholar
Genome-wide association study identifies variants in the MHC class I , IL 10 , and IL 23 R / IL 12 RB 2 regions associated with Behçet ' s disease
E. Remmers, F. Coşan, Y. Kirino, M. Ombrello +37 more
201626 citations
Semantic Scholar
Sensing of apoptotic cells through Axl causes lung basal cell proliferation in inflammatory diseases
N. Fujino, O. Brand, D. Morgan, T. Fujimori +8 more
2019Journal of Experimental Medicine25 citations Open access
Semantic Scholar
Immunogenetic Mechanisms Leading to Thyroid Autoimmunity: Recent Advances in Identifying Susceptibility Genes and Regions
O. Brand, S. Gough
2011Current Genomics25 citations Open access
Semantic Scholar
Confirmation of Association of Chromosome 5q31–33 with United Kingdom Caucasian Graves' Disease
M. Simmonds, K. Yesmin, P. Newby, O. Brand +2 more
2010Thyroid23 citations Open access
Semantic Scholar
Imbalanced prostanoid release mediates cigarette smoke-induced human pulmonary artery cell proliferation
A. Alqarni, O. Brand, A. Pasini, M. Alahmari +2 more
2022Respiratory Research21 citations Open access
Semantic Scholar
The consequence of matrix dysfunction on lung immunity and the microbiome in COPD
T. Hussell, S. Lui, C. Jagger, D. Morgan +1 more
2018European Respiratory Review20 citations Open access
Semantic Scholar
Copy Number Variation in Common Disease
O. Brand, S. Gough
2011Thyroid18 citations
Semantic Scholar
Follow-up of potential novel Graves' disease susceptibility loci, identified in the UK WTCCC genome-wide nonsynonymous SNP study
P. Newby, O. Pickles, Samaresh Mazumdar, O. Brand +6 more
2010European Journal of Human Genetics17 citations Open access
Semantic Scholar
Preliminary evidence for interaction of PTPN12 polymorphism with TSHR genotype and association with Graves’ ophthalmopathy
A. Syed, M. Simmonds, O. Brand, J. Franklyn +2 more
2007Clinical Endocrinology16 citations Open access
Semantic Scholar
Long-Lasting Alterations in T and B Cell Function in Convalescent COVID-19 Patients
H. Shuwa, T. Shaw, S. Knight, Flora A. McClure +20 more
2020Social Science Research Network13 citations
Semantic Scholar
Association of FcGRIIa with Graves’ disease: a potential role for dysregulated autoantibody clearance in disease onset/progression
K. Yesmin, Chantal E. Hargreaves, P. Newby, O. Brand +4 more
2010Clinical Endocrinology12 citations Open access
Semantic Scholar
Experiments on single diving birds in the laboratory often measure dives of decreased effort
L. Halsey, O. Brand, Anthony James Woakes, P. Butler
200611 citations
Semantic Scholar
Neurturin regulates the lung-resident macrophage inflammatory response to viral infection
E. Connolly, D. Morgan, Miriam Franklin, A. Simpson +7 more
2020Life Science Alliance9 citations Open access
Semantic Scholar
Skewing of female X-chromosome inactivation: an epigenetic risk factor for kidney transplantation outcome.
M. Simmonds, D. Benavente, O. Brand, Jason H. Moore +5 more
2013Transplantation8 citations Open access
Semantic Scholar
Recovery of monocyte exhaustion is associated with resolution of lung injury in COVID-19 convalescence.
N. Scott, S. Knight, L. Pearmain, O. Brand +30 more
2020medRxiv7 citations Open access
Semantic Scholar
Use of Tag single nucleotide polymorphisms (SNPs) to screen PTPN21: no association with Graves’ disease
A. Zeitlin, J. Heward, O. Brand, P. Newby +3 more
2006Clinical Endocrinology7 citations Open access
Semantic Scholar
Effect of e-cigarette vapour extraction on vasoactive gene expression in human pulmonary artery smooth muscle and endothelial cells.
A. Alqarni, O. Brand, A. Pasini, M. Alshehri +1 more
2018Pulmonary hypertension2 citations Open access
Semantic Scholar
P115 Cigarettes smoke extract induces inflammatory gene expression in human bronchial epithelial cells
M. Alshehri, O. Brand, A. Alqarni, A. Pasini +1 more
2017Thorax2 citations Open access
Semantic Scholar
Monocyte migratory signatures identify acute and convalescent COVID-19 patients, and are associated with long COVID-19 symptoms
L. Pearmain, N. Scott, S. Knight, O. Brand +26 more
2022Allergy and immunology1 citations
Semantic Scholar
Role of vasoactive mediators on cigarette smoke extract (CSE)-induced proliferation in human pulmonary artery smooth muscle cells (hPASMCs)
A. Alqarni, O. Brand, A. Pasini, Abdulrhman Alghamdi +3 more
2019Pulmonary hypertension1 citations
Semantic Scholar
RAGE Partially Mediates Cigarettes Smoke Extract induced Cytokine and Chemokine Production in Human Bronchial Epithelial Cells
M. Alshehri, O. Brand, A. Alqarni, A. Pasini +1 more
2018Airway Cell Biology and Immunopathology1 citations Open access
Semantic Scholar
S53 Effect of epigenetic inhibitors on lung fibroblast phenotype change in idiopathic pulmonary fibrosis
A. Pasini, O. Brand, Gisli Jenkins, A. Knox +1 more
2016Thorax1 citations Open access
Semantic Scholar
Nasal mucosal lining fluid (MLF) biomarkers for monitoring acute and chronic respiratory disease
Sarah Harbach, O. Brand, S. Knight, J. Vestbo +1 more
2022Monitoring airway disease0 citations
Semantic Scholar
S55 Effect of electronic cigarette extraction on vasoactive gene expression in human pulmonary artery smooth muscle and endothelial cells
A. Alqarni, O. Brand, P. Alice, M. Alshehri +1 more
2018Tobacco dependence and vaping0 citations Open access
Semantic Scholar
The Effect of Cordycepin and Simvastatin on Cigarettes Smoke Extract Induced Cytokine and Chemokine Production in Human Bronchial Epithelial Cells
M. Alshehri, O. Brand, A. Alqarni, A. Pasini +1 more
2018Airway Cell Biology and Immunopathology0 citations
Semantic Scholar

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