J. Au

Most-cited papers

Comprehensive Molecular Characterization of Urothelial Bladder Carcinoma
John N. Rehan Bradley M. Wenyi Roeland G. W. David Seth Weinstein Akbani Broom Wang Verhaak McConkey Lerne, John N. Rehan Bradley M. Wenyi Roeland G. W. David Weinstein Akbani Broom Wang Verhaak McConkey, J. Weinstein, R. Akbani +345 more
2014Nature2,115 citations Open access
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Delivery of siRNA Therapeutics: Barriers and Carriers
Jie Wang, Ze Lu, M. G. Wientjes, J. Au
2010AAPS Journal782 citations Open access
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Drug Delivery and Transport to Solid Tumors
S. Jang, M. G. Wientjes, D. Lu, J. Au
2003Pharmaceutical Research489 citations
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MTDH Activation by 8q22 Genomic Gain Promotes Chemoresistance and Metastasis of Poor-Prognosis Breast Cancer
G. Hu, R. Chong, Qi-Feng Yang, Yong Wei +6 more
2009Cancer Cell430 citations Open access
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Paclitaxel-Loaded Gelatin Nanoparticles for Intravesical Bladder Cancer Therapy
Ze Lu, T. Yeh, Max C. Tsai, J. Au +1 more
2004Clinical Cancer Research249 citations Open access
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Evaluation of Combination Chemotherapy
Liang Zhao, M. Wientjes, J. Au
2004Clinical Cancer Research244 citations Open access
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Fibroblast growth factors: an epigenetic mechanism of broad spectrum resistance to anticancer drugs.
Saeheum Song, M. Wientjes, Y. Gan, J. Au
2000Proceedings of the National Academy of Sciences of the United States of America212 citations Open access
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Delivery of nanomedicines to extracellular and intracellular compartments of a solid tumor
Ying-Huan Li, Jie Wang, M. Wientjes, J. Au
2011Advanced Drug Delivery Reviews208 citations Open access
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Comparison of methods for evaluating drug-drug interaction
Liang Zhao, J. Au, M. Wientjes
2010Frontiers in Bioscience190 citations Open access
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Intravesical Treatments of Bladder Cancer: Review
Zan-Cong Shen, T. Shen, M. Wientjes, Michael A. O'Donnell +1 more
2008Pharmaceutical Research165 citations Open access
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Intraperitoneal therapy for peritoneal cancer
Ze Lu, Jie Wang, M. Wientjes, J. Au
2010Future Oncology157 citations Open access
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Delivery of cancer therapeutics to extracellular and intracellular targets: Determinants, barriers, challenges and opportunities
J. Au, Bertrand Z. Yeung, M. Wientjes, Ze Lu +1 more
2015Advanced Drug Delivery Reviews143 citations Open access
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Effects of Carrier on Disposition and Antitumor Activity of Intraperitoneal Paclitaxel
Max C. Tsai, Ze Lu, Jie Wang, T. Yeh +2 more
2007Pharmaceutical Research128 citations Open access
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Tumor Priming Enhances Delivery and Efficacy of Nanomedicines
D. Lu, M. Wientjes, Ze Lu, J. Au
2007Journal of Pharmacology and Experimental Therapeutics122 citations
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Protection Against Chemotherapy-Induced Alopecia
Jie Wang, Ze Lu, J. Au
2006Pharmaceutical Research122 citations
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Computational model of intracellular pharmacokinetics of paclitaxel.
Hyo-Jeong Kuh, S. Jang, M. Wientjes, J. Au
2000Journal of Pharmacology and Experimental Therapeutics118 citations
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Kinetics of P-glycoprotein-mediated efflux of paclitaxel.
S. Jang, M. Wientjes, J. Au
2001Journal of Pharmacology and Experimental Therapeutics116 citations
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Simultaneous targeting of telomeres and telomerase as a cancer therapeutic approach.
Y. Mo, Y. Gan, Saeheum Song, J. Johnston +3 more
2003Cancer Research103 citations
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Predictive Models of Diffusive Nanoparticle Transport in 3-Dimensional Tumor Cell Spheroids
Yue Gao, Ming-guang Li, Bin Chen, Zan-Cong Shen +3 more
2013AAPS Journal100 citations Open access
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TUMOR PENETRATING MICROPARTICLES FOR INTRAPERITONEAL THERAPY OF OVARIAN CANCER
Ze Lu, Max C. Tsai, D. Lu, Jie Wang +2 more
2008Journal of Pharmacology and Experimental Therapeutics95 citations Open access
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Formulating Paclitaxel in Nanoparticles Alters Its Disposition
T. Yeh, Ze Lu, M. Wientjes, J. Au
2005Pharmaceutical Research95 citations
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Enhancement of paclitaxel delivery to solid tumors by apoptosis-inducing pretreatment: effect of treatment schedule.
S. Jang, M. Wientjes, J. Au
2001Journal of Pharmacology and Experimental Therapeutics95 citations
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Clinical aspects of drug delivery to tumors.
J. Au, S. Jang, M. Wientjes
2002Journal of Controlled Release91 citations
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Improving delivery and efficacy of nanomedicines in solid tumors: Role of tumor priming
Jie Wang, Ze Lu, Yue Gao, M. Wientjes +1 more
2011Nanomedicine86 citations Open access
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Relationships between Liposome Properties, Cell Membrane Binding, Intracellular Processing, and Intracellular Bioavailability
Ying-Huan Li, Jie Wang, Yue Gao, Jia-Bi Zhu +2 more
2011AAPS Journal76 citations Open access
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Expression of Basic Fibroblast Growth Factor Correlates with Resistance to Paclitaxel in Human Patient Tumors
Y. Gan, M. G. Wientjes, J. Au
2006Pharmaceutical Research75 citations
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Exosome is a Mechanism of Intercellular Drug Transfer: Application of Quantitative Pharmacology
Jin Wang, Bertrand Z. Yeung, Minjian Cui, C. Peer +5 more
2017Journal of Controlled Release74 citations Open access
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Nontoxic doses of suramin enhance activity of doxorubicin in prostate tumors.
Yilong Zhang, Saeheum Song, Fan Yang, J. Au +1 more
2001Journal of Pharmacology and Experimental Therapeutics69 citations
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Use of pharmacologic data and computer simulations to design an efficacy trial of intravesical mitomycin C therapy for superficial bladder cancer
M. G. Wientjes, R. Badalament, J. Au
2004Cancer Chemotherapy and Pharmacology66 citations
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Nontoxic doses of suramin enhance activity of paclitaxel against lung metastases.
Saeheum Song, M. Wientjes, Colin T. Walsh, J. Au
2001Cancer Research63 citations
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PACLITAXEL GELATIN NANOPARTICLES FOR INTRAVESICAL BLADDER CANCER THERAPY
Ze Lu, T. Yeh, Jie Wang, Ling-May Chen +8 more
2011Journal of Urology62 citations Open access
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Determinants of Paclitaxel Uptake, Accumulation and Retention in Solid Tumors
S. Jang, M. Wientjes, J. Au
2001Investigational new drugs58 citations Open access
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Effect of dimethyl sulfoxide on bladder tissue penetration of intravesical paclitaxel.
Danny Chen, D. Song, M. Wientjes, J. Au
2003Clinical Cancer Research56 citations
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Paclitaxel Tumor-Priming Enhances siRNA Delivery and Transfection in 3-Dimensional Tumor Cultures
Ho-Lun Wong, Zan-Cong Shen, Ze Lu, M. Wientjes +1 more
2011Molecular Pharmaceutics44 citations Open access
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Low-Dose Suramin Enhanced Paclitaxel Activity in Chemotherapy-Naïve and Paclitaxel-Pretreated Human Breast Xenograft Tumors
Saeheum Song, Bei Yu, Yong Wei, M. Wientjes +1 more
2004Clinical Cancer Research39 citations Open access
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Commentary On Hyperthermia as a treatment for bladder cancer
E. Rampersaud, Ž. Vujašković, B. Inman, J. Au +1 more
2010Oncology38 citations
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Paclitaxel-loaded polymeric microparticles: Quantitative relationships between in vitro drug release rate and in vivo pharmacodynamics
Max C. Tsai, Ze Lu, M. Wientjes, J. Au
2013Journal of Controlled Release36 citations Open access
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Telomere Amount and Length Assay
Y. Gan, K. Engelke, Christopher A. Brown, J. Au
2001Pharmaceutical Research36 citations
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Multiscale Tumor Spatiokinetic Model for Intraperitoneal Therapy
J. Au, Peng Guo, Yue Gao, Ze Lu +3 more
2014AAPS Journal33 citations Open access
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Paclitaxel tumor priming promotes delivery and transfection of intravenous lipid-siRNA in pancreatic tumors
Jie Wang, Ze Lu, Jun-Feng Wang, Minjian Cui +4 more
2015Journal of Controlled Release31 citations Open access
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Tumor priming enhances siRNA delivery and transfection in intraperitoneal tumors
Jie Wang, Ze Lu, Bertrand Z. Yeung, M. Wientjes +2 more
2014Journal of Controlled Release31 citations Open access
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Target Site Delivery and Residence of Nanomedicines: Application of Quantitative Systems Pharmacology
J. Au, R. Abbiati, M. Wientjes, Ze Lu
2019Pharmacological Reviews30 citations Open access
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Predicting diffusive transport of cationic liposomes in 3-dimensional tumor spheroids
M. Wientjes, Bertrand Z. Yeung, Ze Lu, M. Wientjes +1 more
2014Journal of Controlled Release26 citations Open access
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Intravenous siRNA silencing of survivin enhances activity of mitomycin C in human bladder RT4 xenografts
Minjian Cui, J. Au, M. Wientjes, Michael A. O'Donnell +2 more
2015Journal of Urology25 citations Open access
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Telomere maintenance in telomerase‐positive human ovarian SKOV‐3 cells cannot be retarded by complete inhibition of telomerase
Y. Gan, Y. Mo, J. Johnston, Jie Lu +2 more
2002FEBS Letters25 citations Open access
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A pharmacodynamic analysis method to determine the relative importance of drug concentration and treatment time on effect
Nancy J. Millenbaugh, M. G. Wientjes, J. Au
2000Cancer Chemotherapy and Pharmacology25 citations
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Intraprostatic Chemotherapy: Distribution and Transport Mechanisms
M. Wientjes, J. Zheng, Lei-Jun Hu, Y. Gan +1 more
2005Clinical Cancer Research23 citations Open access
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Biodegradable intraprostatic doxorubicin implants
Ronnie Ortiz, J. Au, Ze Lu, Y. Gan +1 more
2007AAPS Journal22 citations Open access
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Phase I trial of non-cytotoxic suramin as a modulator of docetaxel and gemcitabine therapy in previously treated patients with non-small cell lung cancer
E. Lam, J. Au, G. Otterson, M. Wientjes +9 more
2010Cancer Chemotherapy and Pharmacology21 citations Open access
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Versatility of Particulate Carriers: Development of Pharmacodynamically Optimized Drug-Loaded Microparticles for Treatment of Peritoneal Cancer
J. Au, Ze Lu, M. Wientjes
2015AAPS Journal17 citations Open access
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