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Kenji M. Fujihara · SciRah

Researcher profile · Semantic Scholar

Kenji M. Fujihara

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Kenji M. Fujihara — researcher profile on SciRah

h-index: 14
Works: 33
Citations: 487

Most-cited papers

Eprenetapopt triggers ferroptosis, inhibits NFS1 cysteine desulfurase, and synergizes with serine and glycine dietary restriction
Kenji M. Fujihara, Bonnie Z. Zhang, Thomas D. Jackson, M. Ogunkola +18 more
2022Science Advances96 citations Open access
Semantic Scholar
Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome
Yi-Lin Kang, Alexander J. Anderson, Thomas D. Jackson, Catherine S. Palmer +11 more
2019eLife45 citations Open access
Semantic Scholar
SLC7A11 Is a Superior Determinant of APR-246 (Eprenetapopt) Response than TP53 Mutation Status
Kenji M. Fujihara, Mariana Corrales Benitez, C. Cabalag, Bonnie Z. Zhang +8 more
2020Molecular Cancer Therapeutics43 citations Open access
Semantic Scholar
A thiol‐bound drug reservoir enhances APR‐246‐induced mutant p53 tumor cell death
S. Ceder, S. Eriksson, Emarndeena H Cheteh, S. Dawar +12 more
2020EMBO Molecular Medicine35 citations Open access
Semantic Scholar
Allosteric regulation of CAD modulates de novo pyrimidine synthesis during the cell cycle
Jong Shin, Hannan Mir, Maaz Khurram, Kenji M. Fujihara +3 more
2023Nature Metabolism31 citations Open access
Semantic Scholar
Potential Clinical Utility of a Targeted Circulating Tumor DNA Assay in Esophageal Adenocarcinoma
C. Cabalag, Michael Yates, M. B. Corrales, P. Yeh +9 more
2021Annals of Surgery27 citations Open access
Semantic Scholar
Sideroflexin 4 is a complex I assembly factor that interacts with the MCIA complex and is required for the assembly of the ND2 module
Thomas D. Jackson, Jordan J. Crameri, Linden S Muellner-Wong, A. E. Frazier +10 more
2022Proceedings of the National Academy of Sciences of the United States of America25 citations Open access
Semantic Scholar
The TIM22 complex mediates the import of sideroflexins and is required for efficient mitochondrial one-carbon metabolism
Thomas D. Jackson, D. Hock, Kenji M. Fujihara, Catherine S. Palmer +8 more
2021Molecular Biology of the Cell24 citations Open access
Semantic Scholar
Opportunities for Ferroptosis in Cancer Therapy
Kenji M. Fujihara, Bonnie Z. Zhang, N. Clemons
2021Antioxidants22 citations Open access
Semantic Scholar
Molecular comparison of interval and screen‐detected breast cancers
D. Cheasley, Na Li, S. Rowley, K. Elder +22 more
2019Journal of Pathology21 citations Open access
Semantic Scholar
Multiparametric High-Content Cell Painting Identifies Copper Ionophores as Selective Modulators of Esophageal Cancer Phenotypes
Rebecca E. Hughes, Richard J. R. Elliott, Xiao-Dun Li, A. Munro +9 more
2022ACS Chemical Biology19 citations Open access
Semantic Scholar
Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells
S. Ceder, S. Eriksson, Ying-Yu Liang, Emarndeena H Cheteh +9 more
2021Cell Death and Disease18 citations Open access
Semantic Scholar
Loss of SMAD4 Is Sufficient to Promote Tumorigenesis in a Model of Dysplastic Barrett’s Esophagus
Jovana R Gotovac, Tanjina Kader, Julia V. Milne, Kenji M. Fujihara +7 more
2021Cellular and Molecular Gastroenterology and Hepatology17 citations Open access
Semantic Scholar
TGF-beta signaling and its targeted therapy in gastrointestinal cancers.
Jovana R Gotovac, Kenji M. Fujihara, W. Phillips, N. Clemons
2018Discover medicine17 citations
Semantic Scholar
Targeting MDM4 as a Novel Therapeutic Approach in Prostate Cancer Independent of p53 Status
Javier Octavio Mejía-Hernández, Dinesh Raghu, F. Caramia, N. Clemons +20 more
2022Cancers9 citations Open access
Semantic Scholar
The TP53 mutation rate differs in breast cancers that arise in women with high or low mammographic density
D. Cheasley, L. Devereux, Siobhan Hughes, Carolyn Nickson +15 more
2020npj Breast Cancer9 citations Open access
Semantic Scholar
Tumor-Infiltrating Neutrophils after Neoadjuvant Therapy are Associated with Poor Prognosis in Esophageal Cancer
C. Cabalag, O. Prall, J. Ciciulla, L. Galea +12 more
2022Annals of Surgical Oncology8 citations Open access
Semantic Scholar
Bridging the molecular divide: alcohol‐induced downregulation of PAX9 and tumour development
Kenji M. Fujihara, N. Clemons
2018Journal of Pathology7 citations Open access
Semantic Scholar
Transketolase regulates sensitivity to APR-246 in p53-null cells independently of oxidative stress modulation
Julia V. Milne, Bonnie Z. Zhang, Kenji M. Fujihara, S. Dawar +2 more
2021Scientific Reports6 citations Open access
Semantic Scholar
The TIM22 complex regulates mitochondrial one-carbon metabolism by mediating the import of Sideroflexins
Thomas D. Jackson, D. Hock, Catherine S. Palmer, Yi-Lin Kang +5 more
2020bioRxiv5 citations Open access
Semantic Scholar
Genome-wide CRISPR screens reveal APR-246 (Eprenetapopt) triggers ferroptosis and inhibits iron-sulfur cluster biogenesis
Kenji M. Fujihara, Bonnie Z. Zhang, Thomas D. Jackson, Brunda Nijiagel +10 more
2020bioRxiv3 citations Open access
Semantic Scholar
Correction: Mutant p53-reactivating compound APR-246 synergizes with asparaginase in inducing growth suppression in acute lymphoblastic leukemia cells
S. Ceder, S. Eriksson, Ying-Yu Liang, Emarndeena H Cheteh +9 more
2022Cell Death and Disease2 citations Open access
Semantic Scholar
Abstract 601: Translational reprogramming disrupts mitosis to drive SMAD4-deficient esophageal adenocarcinoma.
Julia V. Milne, Ka-Meng Wu, S. Witts, E. Kusnadi +11 more
2026Cancer Research0 citations
Semantic Scholar
Systematic Evaluation Defines the Limits of Ferroptosis in Cancer Therapy
Kenji M. Fujihara, Azmi Aziz, Behnia Akbari, M. Gutiérrez-Pérez +7 more
2026bioRxiv0 citations Open access
Semantic Scholar
SMAD4 loss drives chromosomal instability during tumourigenesis via translational reprogramming
Julia V. Milne, Ka-Meng Wu, E. Kusnadi, S. Brosda +21 more
2026bioRxiv0 citations Open access
Semantic Scholar
ASO Visual Abstract: Tumor-Infiltrating Neutrophils after Neoadjuvant Therapy are Associated with Poor Prognosis in Esophageal Cancer
C. Cabalag, O. Prall, J. Ciciulla, L. Galea +12 more
2022Annals of Surgical Oncology0 citations
Semantic Scholar
814 SMAD4 AS A POTENTIAL GATEKEEPER FOR GENOMIC INSTABILITY AND MTOR-MEDIATED TUMORIGENESIS IN ESOPHAGEAL ADENOCARCINOMA
Julia V. Milne, Jovana R Gotovac, Kenji M. Fujihara, K. Simpson +3 more
2021Diseases of the esophagus0 citations
Semantic Scholar
Abstract 539: Utility of circulating tumor DNA in esophageal cancer: A potential prognostic biomarker in tumor staging, monitoring of treatment response and detection of recurrent disease
C. Cabalag, Michael Yates, M. B. Corrales, P. Yeh +9 more
2021Clinical research0 citations
Semantic Scholar
Abstract 2671: SMAD4 as a potential gatekeeper for genomic instability and mTOR-mediated tumorigenesis in esophageal adenocarcinoma
Julia V. Milne, Jovana R Gotovac, Kenji M. Fujihara, C. Duong +2 more
2021Tumor Biology0 citations Open access
Semantic Scholar
High-content profiling reveals a unified model of copper ionophore dependent cell death in oesophageal adenocarcinoma
Rebecca E. Hughes, Richard J. R. Elliott, Xiao-Dun Li, A. Munro +9 more
2021bioRxiv0 citations Open access
Semantic Scholar
Correction: Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome
Yi-Lin Kang, Alexander J. Anderson, Thomas D. Jackson, Catherine S. Palmer +11 more
2020eLife0 citations Open access
Semantic Scholar
Author response: Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome
Yi-Lin Kang, Alexander J. Anderson, Thomas D. Jackson, Catherine S. Palmer +11 more
20190 citations Open access
Semantic Scholar
Neuronal-specific function of hTim8a in Complex IV assembly provides insight into the molecular mechanism underlying Mohr-Tranebjærg syndrome
Yi-Lin Kang, Alexander J. Anderson, D. D. de Souza, Catherine S. Palmer +10 more
2019bioRxiv0 citations Open access
Semantic Scholar

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