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W. Abraham · SciRah

Researcher profile · Semantic Scholar

W. Abraham

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W. Abraham — researcher profile on SciRah

h-index: 42
Works: 195
Citations: 5,936

Most-cited papers

Literature Review of Florida Red Tide: Implications for Human Health Effects.
B. Kirkpatrick, L. Fleming, D. Squicciarini, L. Backer +9 more
2004Harmful Algae372 citations Open access
Semantic Scholar
The porcine lung as a potential model for cystic fibrosis.
C. Rogers, W. Abraham, K. Brogden, J. Engelhardt +11 more
2008American Journal of Physiology - Lung cellular and Molecular Physiology253 citations Open access
Semantic Scholar
Review of Florida Red Tide and Human Health Effects
L. Fleming, B. Kirkpatrick, L. Backer, C. Walsh +22 more
2011Harmful Algae236 citations Open access
Semantic Scholar
Aerosolized red-tide toxins (brevetoxins) and asthma.
L. Fleming, B. Kirkpatrick, L. Backer, J. Bean +8 more
2007Chest173 citations Open access
Semantic Scholar
Discovery of a potent and selective prostaglandin D2 receptor antagonist, [(3R)-4-(4-chloro-benzyl)-7-fluoro-5-(methylsulfonyl)-1,2,3,4-tetrahydrocyclopenta[b]indol-3-yl]-acetic acid (MK-0524).
C. Sturino, G. O'Neill, N. Lachance, M. Boyd +31 more
2007Journal of Medicinal Chemistry157 citations Open access
Semantic Scholar
Initial Evaluation of the Effects of Aerosolized Florida Red Tide Toxins (Brevetoxins) in Persons with Asthma
L. Fleming, B. Kirkpatrick, L. Backer, J. Bean +16 more
2005Environmental Health Perspectives143 citations Open access
Semantic Scholar
Electronic Cigarette Vapor with Nicotine Causes Airway Mucociliary Dysfunction Preferentially via TRPA1 Receptors.
Samuel Chung, N. Baumlin, J. Dennis, Robert D. Moore +6 more
2019American Journal of Respiratory and Critical Care Medicine110 citations Open access
Semantic Scholar
Airway responses to aerosolized brevetoxins in an animal model of asthma.
W. Abraham, A. Bourdelais, J. Sabater, Ashfaq Ahmed +3 more
2005American Journal of Respiratory and Critical Care Medicine110 citations Open access
Semantic Scholar
Evaluation of Second Generation Amiloride Analogs as Therapy for Cystic Fibrosis Lung Disease
A. Hirsh, J. Sabater, Andra Zamurs, Rick T. Smith +4 more
2004Journal of Pharmacology and Experimental Therapeutics98 citations
Semantic Scholar
Camostat Attenuates Airway Epithelial Sodium Channel Function in Vivo through the Inhibition of a Channel-Activating Protease
K. Coote, H. C. Atherton-Watson, R. Sugar, A. Young +13 more
2009Journal of Pharmacology and Experimental Therapeutics90 citations Open access
Semantic Scholar
Pharmacological Properties of N-(3,5-Diamino-6-chloropyrazine-2-carbonyl)-N′-4-[4-(2,3-dihydroxypropoxy)phenyl]butyl-guanidine Methanesulfonate (552-02), a Novel Epithelial Sodium Channel Blocker with Potential Clinical Efficacy for Cystic Fibrosis Lung Disease
A. Hirsh, Jim Zhang, Andra Zamurs, Jacquelyn Fleegle +10 more
2008Journal of Pharmacology and Experimental Therapeutics88 citations
Semantic Scholar
Indole cytosolic phospholipase A2 alpha inhibitors: discovery and in vitro and in vivo characterization of 4-{3-[5-chloro-2-(2-{[(3,4-dichlorobenzyl)sulfonyl]amino}ethyl)-1-(diphenylmethyl)-1H-indol-3-yl]propyl}benzoic acid, efipladib.
J. McKew, Katherine L. Lee, Marina W. H. Shen, P. Thakker +26 more
2008Journal of Medicinal Chemistry79 citations
Semantic Scholar
Matrix metalloproteinase-12 is a therapeutic target for asthma in children and young adults.
S. Mukhopadhyay, J. Sypek, R. Tavendale, Ulrike Gärtner +13 more
2010Journal of Allergy and Clinical Immunology78 citations Open access
Semantic Scholar
Potent, small-molecule inhibitors of human mast cell tryptase. Antiasthmatic action of a dipeptide-based transition-state analogue containing a benzothiazole ketone.
M. J. Costanzo, S. C. Yabut, H. Almond, P. Andrade-Gordon +7 more
2003Journal of Medicinal Chemistry75 citations Open access
Semantic Scholar
Modeling of asthma, COPD and cystic fibrosis in sheep.
W. Abraham
2008Pulmonary Pharmacology & Therapeutics72 citations
Semantic Scholar
Effects of Inhaled Brevetoxins in Allergic Airways: Toxin–Allergen Interactions and Pharmacologic Intervention
W. Abraham, A. Bourdelais, Ashfaq Ahmed, I. Serebriakov +1 more
2005Environmental Health Perspectives67 citations Open access
Semantic Scholar
Exposure and Effect Assessment of Aerosolized Red Tide Toxins (Brevetoxins) and Asthma
L. Fleming, J. Bean, B. Kirkpatrick, Yung-Sung Cheng +17 more
2009Environmental Health Perspectives64 citations Open access
Semantic Scholar
Dual inhibition of cathepsin G and chymase is effective in animal models of pulmonary inflammation.
B. Maryanoff, L. de Garavilla, M. Greco, B. Haertlein +3 more
2010American Journal of Respiratory and Critical Care Medicine59 citations
Semantic Scholar
Efficacy of IL-13 neutralization in a sheep model of experimental asthma.
M. Kasaian, D. Donaldson, Lioudmila Tchistiakova, Kimberly Marquette +9 more
2007American Journal of Respiratory Cell and Molecular Biology58 citations Open access
Semantic Scholar
Therapeutic targeting of endothelial ligands for L-selectin (PNAd) in a sheep model of asthma.
S. Rosen, D. Tsay, M. Singer, S. Hemmerich +1 more
2005American Journal of Pathology58 citations Open access
Semantic Scholar
Peptide and non-peptide bradykinin receptor antagonists: role in allergic airway disease.
W. Abraham, M. Scuri, S. G. Farmer
2006European Journal of Pharmacology55 citations
Semantic Scholar
Aerosolized Red Tide Toxins (Brevetoxins) and Asthma: Continued health effects after 1 hour beach exposure
B. Kirkpatrick, L. Fleming, J. Bean, K. Nierenberg +10 more
2011Harmful Algae54 citations Open access
Semantic Scholar
Pharmacological Characterization of MK-7246, a Potent and Selective CRTH2 (Chemoattractant Receptor-Homologous Molecule Expressed on T-Helper Type 2 Cells) Antagonist
F. G. Gervais, N. Sawyer, R. Stocco, M. Hamel +10 more
2011Molecular Pharmacology54 citations
Semantic Scholar
SPX‐101 Is a Novel Epithelial Sodium Channel‐targeted Therapeutic for Cystic Fibrosis That Restores Mucus Transport
D. Scott, M. Walker, Juliana I. Sesma, Bryant Wu +6 more
2017American Journal of Respiratory and Critical Care Medicine48 citations
Semantic Scholar
Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives.
M. J. Costanzo, S. C. Yabut, Han-Cheng Zhang, Kimberley B. White +12 more
2008Bioorganic & Medicinal Chemistry Letters44 citations Open access
Semantic Scholar
Specific inhibition of tissue kallikrein 1 with a human monoclonal antibody reveals a potential role in airway diseases.
D. Sexton, Ting Chen, Diana Martik, P. Kuzmič +7 more
2009Biochemical Journal42 citations Open access
Semantic Scholar
Preclinical pharmacokinetics, interspecies scaling, and tissue distribution of humanized monoclonal anti-IL-13 antibodies with different IL-13 neutralization mechanisms.
Y. Vugmeyster, P. Szklut, Lioudmila Tchistiakova, W. Abraham +2 more
2008International Immunopharmacology42 citations
Semantic Scholar
Identification of an orally efficacious matrix metalloprotease 12 inhibitor for potential treatment of asthma.
Wei Li, Jian-Chang Li, Yuchuan Wu, F. Rancati +16 more
2009Journal of Medicinal Chemistry41 citations Open access
Semantic Scholar
Losartan Rescues Inflammation-Related Mucociliary Dysfunction in Relevant Models of Cystic Fibrosis.
Michael D. Kim, N. Baumlin, Makoto Yoshida, Deepika Polineni +11 more
2020American Journal of Respiratory and Critical Care Medicine37 citations Open access
Semantic Scholar
A Monoclonal Antibody to α1β1 Blocks Antigen-induced Airway Responses in Sheep
W. Abraham, Ashfaq Ahmed, I. Serebriakov, Amie N. Carmillo +7 more
200437 citations
Semantic Scholar
Leukocytic cell sources of airway tissue kallikrein.
I. Lauredo, R. Forteza, Y. Botvinnikova, W. Abraham
2004American Journal of Physiology - Lung cellular and Molecular Physiology34 citations Open access
Semantic Scholar
Characterization of Tamulamides A and B: Polyethers Isolated from the Marine Dinoflagellate Karenia brevis
L. Truxal, A. Bourdelais, H. Jacocks, W. Abraham +1 more
2010Journal of Natural Products33 citations Open access
Semantic Scholar
Comparative effects of salmeterol, albuterol, and ipratropium on normal and impaired mucociliary function in sheep.
J. Sabater, Troy A. Lee, W. Abraham
2005Chest32 citations
Semantic Scholar
Preclinical Evaluation of an Inhibitor of Cytosolic Phospholipase A2α for the Treatment of Asthma
C. Hewson, Sheena Patel, L. Calzetta, H. Campwala +13 more
2012Journal of Pharmacology and Experimental Therapeutics30 citations
Semantic Scholar
Evaluation of a SPLUNC1-derived peptide for the treatment of cystic fibrosis lung disease.
S. Terryah, R. Fellner, Saira Ahmad, P. J. Moore +12 more
2018American Journal of Physiology - Lung cellular and Molecular Physiology27 citations Open access
Semantic Scholar
Inhibition of spleen tyrosine kinase attenuates allergen-mediated airway constriction.
L. Moy, Yan-Lin Jia, Michael Caniga, G. Lieber +20 more
2013American Journal of Respiratory Cell and Molecular Biology26 citations
Semantic Scholar
Low-volume resuscitation from traumatic hemorrhagic shock with Na+/H+ exchanger inhibitor*
Dong-Mei Wu, Hui Dai, Jaqueline Arias, L. Latta +1 more
2009Critical Care Medicine26 citations
Semantic Scholar
Receptor-Mediated Enhancement of Beta Adrenergic Drug Activity by Ascorbate In Vitro and In Vivo
P. Dillon, R. Root-Bernstein, N. Robinson, W. Abraham +1 more
2010PLoS ONE24 citations Open access
Semantic Scholar
Na+/H+ EXCHANGE INHIBITION DELAYS THE ONSET OF HYPOVOLEMIC CIRCULATORY SHOCK IN PIGS
Dong-Mei Wu, Jaqueline Arias, Jorge A. Bassuk, H. Doods +3 more
2007Shock24 citations Open access
Semantic Scholar
Benzenesulfonamide indole inhibitors of cytosolic phospholipase A2alpha: optimization of in vitro potency and rat pharmacokinetics for oral efficacy.
Katherine L. Lee, M. Behnke, M. Foley, Lih-Ren Chen +14 more
2008Bioorganic & Medicinal Chemistry23 citations
Semantic Scholar
Kinin B1 receptor antagonist BI113823 reduces allergen-induced airway inflammation and mucus secretion in mice.
Malarvizhi Gurusamy, Saeed Nasseri, Han-Koo Lee, Birgit Jung +5 more
2016Pharmacological Research22 citations
Semantic Scholar
NVP‐QBE170: an inhaled blocker of the epithelial sodium channel with a reduced potential to induce hyperkalaemia
K. Coote, D. Paisley, S. Czarnecki, M. Tweed +19 more
2015British Journal of Pharmacology22 citations Open access
Semantic Scholar
Discovery of an Oral Potent Selective Inhibitor of Hematopoietic Prostaglandin D Synthase (HPGDS).
C. Carron, John I. Trujillo, Kirk L. Olson, Wei Huang +31 more
2010ACS Medicinal Chemistry Letters22 citations Open access
Semantic Scholar
Effect of the potent and selective DP1 receptor antagonist, asapiprant (S-555739), in animal models of allergic rhinitis and allergic asthma.
Go Takahashi, F. Asanuma, N. Suzuki, M. Hattori +8 more
2015European Journal of Pharmacology20 citations
Semantic Scholar
Aerosolized Florida Red Tide Toxins and Human Health Effects.
W. Abraham, D. Baden
2006Oceanography20 citations Open access
Semantic Scholar
Sabiporide Improves Cardiovascular Function, Decreases the Inflammatory Response and Reduces Mortality in Acute Metabolic Acidosis in Pigs
Dong-Mei Wu, J. Kraut, W. Abraham
2013PLoS ONE18 citations Open access
Semantic Scholar
Florida Red Tide Toxins (Brevetoxins) and Longitudinal Respiratory Effects in Asthmatics
J. Bean, L. Fleming, B. Kirkpatrick, L. Backer +13 more
2011Harmful Algae18 citations Open access
Semantic Scholar
Inhibition of allergic airway responses by heparin derived oligosaccharides: identification of a tetrasaccharide sequence
T. Ahmed, Gregory Smith, I. Vlahov, W. Abraham
2012Respiratory Research17 citations Open access
Semantic Scholar
Whole-body periodic acceleration modifies experimental asthma in sheep.
W. Abraham, Ashfaq Ahmed, I. Serebriakov, I. Lauredo +3 more
2006American Journal of Respiratory and Critical Care Medicine17 citations Open access
Semantic Scholar
Repeated exposure to aerosolized brevetoxin-3 induces prolonged airway hyperresponsiveness and lung inflammation in sheep
J. Zaias, L. Fleming, D. Baden, W. Abraham
2011Inhalation Toxicology16 citations
Semantic Scholar

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