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N. Antonakos · SciRah

Researcher profile · Semantic Scholar

N. Antonakos

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N. Antonakos — researcher profile on SciRah

h-index: 17
Works: 49
Citations: 3,403

Most-cited papers

Complex Immune Dysregulation in COVID-19 Patients with Severe Respiratory Failure
E. Giamarellos-Bourboulis, M. Netea, N. Rovina, K. Akinosoglou +24 more
2020Cell Host and Microbe1,965 citations Open access
Semantic Scholar
Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly
E. Giamarellos-Bourboulis, M. Tsilika, S. Moorlag, N. Antonakos +15 more
2020Cell373 citations Open access
Semantic Scholar
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients
A. Aschenbrenner, M. Mouktaroudi, B. Krämer, N. Antonakos +50 more
2020Genome Medicine204 citations Open access
Semantic Scholar
Toward personalized immunotherapy in sepsis: The PROVIDE randomized clinical trial
K. Leventogiannis, E. Kyriazopoulou, N. Antonakos, A. Kotsaki +20 more
2022Cell Reports Medicine147 citations Open access
Semantic Scholar
Precision Immunotherapy to Improve Sepsis Outcomes: The ImmunoSep Randomized Clinical Trial.
E. Giamarellos-Bourboulis, A. Kotsaki, I. Kotsamidi, Aikaterini Efthymiou +50 more
2025Journal of the American Medical Association (JAMA)113 citations Open access
Semantic Scholar
Transcriptomic similarities and differences in host response between SARS-CoV-2 and other viral infections
Simone A. Thair, Yudong He, Y. Hasin-Brumshtein, S. Sakaram +15 more
2020medRxiv85 citations Open access
Semantic Scholar
Bloodstream infections and sepsis in Greece: over-time change of epidemiology and impact of de-escalation on final outcome
Marina Koupetori, Theodoros Retsas, N. Antonakos, G. Vlachogiannis +10 more
2014BMC Infectious Diseases57 citations Open access
Semantic Scholar
ImmunoSep (Personalised Immunotherapy in Sepsis) international double-blind, double-dummy, placebo-controlled randomised clinical trial: study protocol
A. Kotsaki, P. Pickkers, M. Bauer, T. Calandra +16 more
2022BMJ Open56 citations Open access
Semantic Scholar
Increase of circulating endocan over sepsis follow-up is associated with progression into organ dysfunction
A. Ioakeimidou, E. Pagalou, Marina Kontogiorgi, Eleni Antoniadou +7 more
2017European Journal of Clinical Microbiology and Infectious Diseases49 citations Open access
Semantic Scholar
Clarithromycin for early anti-inflammatory responses in community-acquired pneumonia in Greece (ACCESS): a randomised, double-blind, placebo-controlled trial.
E. Giamarellos-Bourboulis, A. Siampanos, Amalia Bolanou, Sarantia Doulou +28 more
2024The Lancet Respiratory Medicine44 citations
Semantic Scholar
Sepsis pathogenesis and outcome are shaped by the balance between the transcriptional states of systemic inflammation and antimicrobial response
Rachel Brandes-Leibovitz, A. Riza, Gal Yankovitz, A. Pîrvu +19 more
2024Cell Reports Medicine37 citations Open access
Semantic Scholar
Decreased cytokine production by mononuclear cells after severe gram-negative infections: early clinical signs and association with final outcome
N. Antonakos, T. Tsaganos, V. Oberle, I. Tsangaris +6 more
2017Critical Care29 citations Open access
Semantic Scholar
Disease severity-specific neutrophil signatures in blood transcriptomes stratify COVID-19 patients
A. Aschenbrenner, M. Mouktaroudi, B. Krämer, Marie Oestreich +51 more
2021Genome Medicine28 citations Open access
Semantic Scholar
The association of TSH and thyroid hormones with lymphopenia in bacterial sepsis and COVID-19
I. Grondman, A. D. de Nooijer, N. Antonakos, N. Janssen +13 more
2021Journal of Clinical Endocrinology and Metabolism25 citations Open access
Semantic Scholar
Prognostic Role of Soluble Urokinase Plasminogen Activator Receptor at the Emergency Department: A Position Paper by the Hellenic Sepsis Study Group
D. Velissaris, G. Dimopoulos, J. Parissis, Zoi Alexiou +13 more
2020Infectious Disease and Therapy24 citations Open access
Semantic Scholar
Host cystathionine-γ lyase derived hydrogen sulfide protects against Pseudomonas aeruginosa sepsis
Georgios Renieris, Dionysia-Eirini Droggiti, K. Katrini, P. Koufargyris +16 more
2021PLoS Pathogens22 citations Open access
Semantic Scholar
qSOFA combined with suPAR for early risk detection and guidance of antibiotic treatment in the emergency department: a randomized controlled trial
M. Adami, A. Kotsaki, N. Antonakos, E. Giannitsioti +13 more
2024Critical Care20 citations Open access
Semantic Scholar
A 6-mRNA host response classifier in whole blood predicts outcomes in COVID-19 and other acute viral infections
L. Buturovic, Hong Zheng, Benjamin Tang, Kevin Lai +28 more
2022Scientific Reports17 citations Open access
Semantic Scholar
-572 G/C single nucleotide polymorphism of interleukin-6 and sepsis predisposition in chronic renal disease
A. Panayides, A. Ioakeimidou, Vasilios Karamouzos, N. Antonakos +10 more
2015European Journal of Clinical Microbiology and Infectious Diseases13 citations Open access
Semantic Scholar
Modulation of Metabolomic Profile in Sepsis According to the State of Immune Activation
Eleftheria Kranidioti, I. Ricaño-Ponce, N. Antonakos, E. Kyriazopoulou +16 more
2024Critical Care Medicine11 citations Open access
Semantic Scholar
Early changes of the kinetics of monocyte trem-1 reflect final outcome in human sepsis
Androniki Marioli, Marina Koupetori, M. Raftogiannis, M. Patrani +6 more
2014BMC Immunology11 citations Open access
Semantic Scholar
Epidemiology of Mucormycosis in Greece; Results from a Nationwide Prospective Survey and Published Case Reports
M. Drogari-Apiranthitou, A. Skiada, I. Panayiotides, T. Vyzantiadis +23 more
2023Journal of Fungi10 citations Open access
Semantic Scholar
THE ROLE OF OBESITY AND PLASMA ADIPOCYTOKINES IN IMMUNE DYSREGULATION IN SEPSIS PATIENTS
A. D. de Nooijer, N. Antonakos, Dimitra Markopoulou, I. Grondman +4 more
2022Shock10 citations Open access
Semantic Scholar
Efficacy of anakinra in reducing progression to organ dysfunction in patients with pneumonia (INSPIRE): a randomised, double-blind, placebo-controlled, phase IIa trial
Georgios Tavoulareas, Olga Kontakou-Zoniou, N. Antonakos, E. Tasouli +10 more
2025The Lancet Regional Health - Europe9 citations
Semantic Scholar
Prognostic Role of Soluble Urokinase Plasminogen Activator Receptor at the Emergency Department: A Position Paper by the Hellenic Sepsis Study Group.
D. Velissaris, G. Dimopoulos, J. Parissis, Zoi Alexiou +13 more
2020Infectious Disease and Therapy9 citations Open access
Semantic Scholar
Evaluation of the Novel Sepsis Biomarker Host-Derived Delta-like Canonical Notch Ligand 1—A Secondary Analysis of 405 Patients Suffering from Inflammatory or Infectious Diseases
Tobias Hölle, Patrick Rehn, K. Leventogiannis, A. Kotsaki +10 more
2023International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
A 6-mRNA host response whole-blood classifier trained using patients with non-COVID-19 viral infections accurately predicts severity of COVID-19
L. Buturovic, Hong Zheng, Benjamin Tang, Kevin Lai +28 more
2020medRxiv7 citations Open access
Semantic Scholar
A novel optical biosensor for the early diagnosis of sepsis and severe Covid-19: the PROUD study
Sarantia Doulou, K. Leventogiannis, M. Tsilika, M. Rodencal +11 more
2020BMC Infectious Diseases7 citations Open access
Semantic Scholar
Regulation of plasma soluble receptors of TNF and IL-1 in patients with COVID-19 differs from that observed in sepsis
Muhammed D. Aksu, Tijmen van der Ent, Zhen-Hua Zhang, A. Riza +16 more
2024Journal of Infection6 citations Open access
Semantic Scholar
Towards Personalized Immunotherapy in Sepsis: The PROVIDE Randomized Clinical Trial
K. Leventogiannis, E. Kyriazopoulou, N. Antonakos, A. Kotsaki +20 more
2022Social Science Research Network4 citations Open access
Semantic Scholar
BIOMARKERS: CAN THEY REALLY GUIDE OUR DAILY PRACTICE?
I. Tsangaris, N. Antonakos, M. Fantoni, G. Kaplanski +3 more
2022Shock4 citations Open access
Semantic Scholar
A Nationwide Study of the Delayed Diagnosis and the Clinical Manifestations of Predominantly Antibody Deficiencies and CTLA4-Mediated Immune Dysregulation Syndrome in Greece
Androniki Kapousouzi, F. Kalala, S. Sarrou, E. Farmaki +17 more
2024Medicina3 citations Open access
Semantic Scholar
An active new formulation of iron carried by aspartyl casein for iron-deficiency anemia: results of the ACCESS trial
M. Tsilika, J. Mitrou, N. Antonakos, Ioulia K. Tseti +3 more
2023Annals of Hematology3 citations Open access
Semantic Scholar
Single-cell transcriptomics identifies different immune signatures between macrophage activation-like syndrome and immune paralysis in sepsis
I. Grondman, V. Koeken, A. Karageorgos, W. Li +7 more
2023medRxiv3 citations Open access
Semantic Scholar
A human-specific long noncoding RNA regulator of antigen-presenting cell viability and antimicrobial defense.
A. Westermann, Alexandra Schock, Diyaa Al Din Ashour, Sarah Wende +11 more
2026Proceedings of the National Academy of Sciences of the United States of America2 citations Open access
Semantic Scholar
Blood Biomarker and Raman Analysis of Leukocytes in the Multicenter Intelligence Trials: At the Intensive Care Unit (Intelligence-1) and the Emergency Department (Intelligence-2)
E. Giamarellos-Bourboulis, Daniel O. Thomas-Rüddel, Aikaterini Pistiki, A. Ramoji +23 more
2025Shock2 citations Open access
Semantic Scholar
Interleukin-6 is a mediator of therapeutic efficacy in acute lung injury
L. Kramer, C. Calfee, D. Mcauley, C. O'Kane +6 more
2026American Journal of Respiratory and Critical Care Medicine1 citations Open access
Semantic Scholar
630. A 5-mRNA host response whole-blood classifier trained using patients with non-COVID-19 viral infections accurately predicts severity of COVID-19
L. Buturovic, P. Khatri, B. Tang, Kevin Lai +22 more
2020Open Forum Infectious Diseases1 citations Open access
Semantic Scholar
IMPACT OF COMORBIDITIES ON THE PERFORMANCE OF INTERFERON GAMMA RELEASE ASSAY IN A GREEK ELDERLY POPULATION WITHOUT OVERT IMMUNODEFICIENCY.
M. Tsilika, N. Antonakos, T. Gkavogianni, A. Karageorgos +3 more
2020International Journal of Antimicrobial Agents1 citations
Semantic Scholar
Change of annexin binding of monocytes as an expression of cellular response to Candida albicans: down-regulation in severe sepsis
A. Pistiki, T. Tsaganos, I. Tsangaris, N. Antonakos +2 more
2016European Journal of Clinical Microbiology and Infectious Diseases1 citations
Semantic Scholar
Clarithromycin in community-acquired pneumonia: a within-trial cost analysis of the ACCESS randomised, double-blind, placebo-controlled study
Vassiliki Rapti, N. Antonakos, Pavlina Mesiri, E. Giamarellos-Bourboulis +1 more
2026BMC Infectious Diseases0 citations Open access
Semantic Scholar
Innate immune response in COVID-19 pneumonia during the pandemic: a prospective cohort study
Stavroula-Porfyria Chachali, S. Foutadakis, N. Antonakos, K. Leventogiannis +2 more
2026Annals of Intensive Care0 citations Open access
Semantic Scholar
Distinct transcriptomic signatures discriminate hyperinflammation from immune paralysis in sepsis: a single-cell RNA sequencing study
I. Grondman, V. Koeken, Tristan Couwenbergh, A. Karageorgos +9 more
2026Critical Care0 citations Open access
Semantic Scholar
A 6-mRNA host response classifier in whole blood predicts outcomes in COVID-19 and other acute viral infections
L. Buturovic, Hong Zheng, Benjamin Tang, Kevin Lai +28 more
2022Scientific Reports0 citations Open access
Semantic Scholar
Abnormal Thyroid Function Is Associated With Lymphopenia in Bacterial Sepsis and COVID-19
I. Grondman, A. D. de Nooijer, N. Antonakos, N. Janssen +9 more
2021Journal of the Endocrine Society0 citations Open access
Semantic Scholar
521. Similarities and Differences in Transcriptomic Host Response between SARS-CoV-2 and Other Viral Infections
Simone A. Thair, Yudong He, Y. Hasin-Brumshtein, S. Sakaram +16 more
2020Open Forum Infectious Diseases0 citations Open access
Semantic Scholar
A 6-mRNA host response whole-blood classifier trained on pre-pandemic data accurately predicts severity in COVID-19 and other acute viral infections
L. Buturovic, Hong Zheng, Benjamin Tang, Kevin Lai +28 more
20200 citations Open access
Semantic Scholar
Change of annexin binding of monocytes as an expression of cellular response to Candida albicans: down-regulation in severe sepsis
A. Pistiki, T. Tsaganos, I. Tsangaris, N. Antonakos +2 more
2016European Journal of Clinical Microbiology and Infectious Diseases0 citations
Semantic Scholar
Early changes of the kinetics of monocyte trem-1 reflect final outcome in human sepsis
Androniki Marioli, Marina Koupetori, M. Raftogiannis, M. Patrani +6 more
2014BMC Immunology0 citations Open access
Semantic Scholar
A rare case of dysphagia in a severely immunocompromised patient
A. Sioulas, I. Panayiotides, Dimitra Kavatha, P. Foukas +2 more
2012Archives of medical science : AMS0 citations Open access
Semantic Scholar

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