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E. Giamarellos-Bourboulis · SciRah

Researcher profile · Semantic Scholar

E. Giamarellos-Bourboulis

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E. Giamarellos-Bourboulis — researcher profile on SciRah

h-index: 83
Works: 709
Citations: 33K

Most-cited papers

The pathophysiology of sepsis and precision-medicine-based immunotherapy
E. Giamarellos-Bourboulis, A. Aschenbrenner, Michael Bauer, Christoph Bock +13 more
2024Nature Immunology351 citations Open access
Semantic Scholar
Efficacy and safety of bimekizumab in patients with moderate-to-severe hidradenitis suppurativa (BE HEARD I and BE HEARD II): two 48-week, randomised, double-blind, placebo-controlled, multicentre phase 3 trials.
A. Kimball, G. Jemec, Christopher J. Sayed, J. Kirby +16 more
2024The Lancet122 citations Open access
Semantic Scholar
Precision Immunotherapy to Improve Sepsis Outcomes: The ImmunoSep Randomized Clinical Trial.
E. Giamarellos-Bourboulis, A. Kotsaki, I. Kotsamidi, Aikaterini Efthymiou +50 more
2025Journal of the American Medical Association (JAMA)113 citations Open access
Semantic Scholar
A consensus immune dysregulation framework for sepsis and critical illnesses
Andrew R. Moore, Hong Zheng, A. Ganesan, Y. Hasin-Brumshtein +24 more
2025Nature Medicine87 citations Open access
Semantic Scholar
The immunology of sepsis: translating new insights into clinical practice
M. Kox, Michael Bauer, Lieuwe D. J. Bos, H. Bouma +20 more
2025Nature Reviews Nephrology66 citations Open access
Semantic Scholar
Towards personalized medicine: a scoping review of immunotherapy in sepsis
M. A. Slim, N. van Mourik, Lieke Bakkerus, Katherine Fuller +12 more
2024Critical Care63 citations Open access
Semantic Scholar
Sepsis in patients who are immunocompromised: diagnostic challenges and future therapies.
Stefanie Deinhardt-Emmer, B. Chousterman, J. Schefold, Stefanie B. Flohé +20 more
2025The Lancet Respiratory Medicine49 citations Open access
Semantic Scholar
Sepsis pathogenesis and outcome are shaped by the balance between the transcriptional states of systemic inflammation and antimicrobial response
Rachel Brandes-Leibovitz, A. Riza, Gal Yankovitz, A. Pîrvu +19 more
2024Cell Reports Medicine37 citations Open access
Semantic Scholar
Prevalence of Hidradenitis Suppurativa: A Meta-Analysis of Global Hidradenitis Suppurativa Atlas Studies.
D. Bouazzi, S. Nielsen, P. Hagan, Sofia Botvid +60 more
2025JAMA dermatology31 citations Open access
Semantic Scholar
Clinical validation of an AI-based blood testing device for diagnosis and prognosis of acute infection and sepsis
Oliver Liesenfeld, S. Arora, T. Aufderheide, Casey M. Clements +30 more
2025Nature Medicine31 citations Open access
Semantic Scholar
Interferon-gamma driven elevation of CXCL9: a new sepsis endotype independently associated with mortality
E. Giamarellos-Bourboulis, M. Antonelli, F. Bloos, I. Kotsamidi +23 more
2024EBioMedicine31 citations
Semantic Scholar
Biomarkers to guide sepsis management
Vasiliki Bourika, Evangelia-Areti Rekoumi, E. Giamarellos-Bourboulis
2025Annals of Intensive Care28 citations Open access
Semantic Scholar
Recent advances of precision immunotherapy in sepsis
Antonios Arapis, Dimitrios Panagiotopoulos, E. Giamarellos-Bourboulis
2025Burns & Trauma27 citations Open access
Semantic Scholar
Status of Sepsis Care in European Hospitals: Results from an International Cross-Sectional Survey
Christian S. Scheer, E. Giamarellos-Bourboulis, Ricard Ferrer, Evgeny A. Idelevich +32 more
2025American Journal of Respiratory and Critical Care Medicine22 citations Open access
Semantic Scholar
qSOFA combined with suPAR for early risk detection and guidance of antibiotic treatment in the emergency department: a randomized controlled trial
M. Adami, A. Kotsaki, N. Antonakos, E. Giannitsioti +13 more
2024Critical Care20 citations Open access
Semantic Scholar
Long-term efficacy and safety of secukinumab in patients with moderate-to-severe hidradenitis suppurativa: Week 104 results from the SUNSHINE and SUNRISE extension trial.
A. Kimball, F. Bechara, A. Badat, E. Giamarellos-Bourboulis +13 more
2024British Journal of Dermatology18 citations Open access
Semantic Scholar
Quantifying immune dysregulation in pneumonia and sepsis with a parsimonious machine-learning model: a multicohort analysis across care settings and reanalysis of a hydrocortisone randomised controlled trial.
Erik H. A. Michels, P. Dequin, J. Butler, Antoine Guillon +24 more
2026The Lancet Respiratory Medicine17 citations
Semantic Scholar
Transitions of blood immune endotypes and improved outcome by anakinra in COVID-19 pneumonia: an analysis of the SAVE-MORE randomized controlled trial
E. Kyriazopoulou, Y. Hasin-Brumshtein, U. Midic, Garyfallia Poulakou +40 more
2024Critical Care17 citations Open access
Semantic Scholar
IFNγ in human sepsis: a scoping review
Daniel O. Thomas-Rüddel, E. Giamarellos-Bourboulis, Caroline Neumann, Josef Briegel +40 more
2025Annals of Intensive Care14 citations Open access
Semantic Scholar
Biomarker guided immunomodulatory precision medicine to improve prognostic, predictive and adaptive enrichment strategies in sepsis trials
A. Alevizou, Panagiota Soulioti, E. Giamarellos-Bourboulis, A. Safarika
2025Expert Review of Molecular Diagnostics13 citations
Semantic Scholar
SuPAR, Biomarkers of Inflammation, and Severe Outcomes in Patients Hospitalized for COVID-19: The International Study of Inflammation in COVID-19
A. Vasbinder, Kishan Padalia, Ian Pizzo, Kristen Machado +29 more
2024Journal of Medical Virology12 citations Open access
Semantic Scholar
Obesity, Inflammation, and Clinical Outcomes in COVID-19: A Multicenter Prospective Cohort Study
Christina G. Hutten, Kishan Padalia, A. Vasbinder, Yi-Yuan Huang +18 more
2024Journal of Clinical Endocrinology and Metabolism12 citations Open access
Semantic Scholar
Modulation of Metabolomic Profile in Sepsis According to the State of Immune Activation
Eleftheria Kranidioti, I. Ricaño-Ponce, N. Antonakos, E. Kyriazopoulou +16 more
2024Critical Care Medicine11 citations Open access
Semantic Scholar
Efficacy of anakinra in reducing progression to organ dysfunction in patients with pneumonia (INSPIRE): a randomised, double-blind, placebo-controlled, phase IIa trial
Georgios Tavoulareas, Olga Kontakou-Zoniou, N. Antonakos, E. Tasouli +10 more
2025The Lancet Regional Health - Europe9 citations
Semantic Scholar
Third generation sequencing analysis detects significant differences in duodenal microbiome composition between functional dyspepsia patients and control subjects
G. Tziatzios, Emmanouil Stylianakis, G. Damoraki, P. Gkolfakis +5 more
2024Neurogastroenterology and Motility9 citations Open access
Semantic Scholar
Risk assessment with gene expression markers in sepsis development
A. García López, S. Schäuble, Tongta Sae-Ong, Bastian Seelbinder +5 more
2024Cell Reports Medicine9 citations Open access
Semantic Scholar
An evaluation of secukinumab for the treatment of moderate-to-severe hidradenitis suppurativa
D. Stergianou, T. Kanni, Christina Damoulari, E. Giamarellos-Bourboulis
2024Expert Opinion on Biological Therapy9 citations
Semantic Scholar
Clarithromycin For Improved Clinical Outcomes in Community-Acquired Pneumonia: A Subgroup Analysis of the ACCESS Study.
K. Akinosoglou, K. Leventogiannis, E. Tasouli, Nikolaos Kakavoulis +20 more
2024International Journal of Antimicrobial Agents9 citations Open access
Semantic Scholar
Targeting mTOR in myeloid cells prevents infection-associated inflammation
Y. C. Toner, J. Munitz, Geoffrey Prévot, J. Morla-Folch +39 more
2025iScience8 citations Open access
Semantic Scholar
Towards improved point-of-care (POC) testing for patients with suspected sepsis: POC tests for host biomarkers and possible microbial pathogens
M. Adami, E. Giamarellos-Bourboulis, E. Polyzogopoulou
2024Expert Review of Molecular Diagnostics8 citations
Semantic Scholar
Infrastructure and current practice of blood culture diagnostics in patients with sepsis: teachings and recommendations from the European Sepsis Care Survey
Christian S. Scheer, Djillali Annane, Antonio Artigas, A. Linder +4 more
2025Critical Care7 citations Open access
Semantic Scholar
Regulation of plasma soluble receptors of TNF and IL-1 in patients with COVID-19 differs from that observed in sepsis
Muhammed D. Aksu, Tijmen van der Ent, Zhen-Hua Zhang, A. Riza +16 more
2024Journal of Infection6 citations Open access
Semantic Scholar
Intubation Decision Based on Illness Severity and Mortality in COVID-19: An International Study*
A. Chalkias, Yi-Yuan Huang, A. Ismail, Ioannis Pantazopoulos +23 more
2024Critical Care Medicine6 citations
Semantic Scholar
ANAKINRA EFFICACY IN COVID-19 PNEUMONIA GUIDED BY SOLUBLE UROKINASE PLASMINOGEN ACTIVATOR RECEPTOR: ASSOCIATION WITH THE INFLAMMATORY BURDEN OF THE HOST.
E. Kyriazopoulou, K. Akinosoglou, Eleni Florou, Elli Kouriannidi +34 more
2024International Journal of Antimicrobial Agents6 citations Open access
Semantic Scholar
Systematic review and meta-analysis of humoral immunity proteins and mortality in sepsis
Antoine Villa, F. Dewar, W. Pisciotta, Ankita Rai +33 more
2025Critical Care5 citations Open access
Semantic Scholar
Vilobelimab to improve clinical outcomes of moderate-to-severe hidradenitis suppurativa through an adjunctive effect on draining tunnels: Results of the SHINE double-blind, placebo-controlled randomised trial.
E. Giamarellos-Bourboulis, G. Jemec, E. Prens, N. Riedemann +21 more
2025British Journal of Dermatology5 citations Open access
Semantic Scholar
Pancreatic Stone Protein in Co-Evaluation With QSOFA and News2 for Early Sepsis Detection at the Emergency Department
A. Safarika, G. Damoraki, K. Katsaros, Soraya Hannane +4 more
2025Shock5 citations Open access
Semantic Scholar
International multi-cohort analysis identifies novel framework for quantifying immune dysregulation in critical illness: results of the SUBSPACE consortium
Andrew R. Moore, Hong Zheng, A. Ganesan, Y. Hasin-Brumshtein +21 more
2024bioRxiv5 citations Open access
Semantic Scholar
Long-term immune and epigenetic dysregulation following COVID-19.
Chrysanthi Sidiropoulou, G. Poulakou, E. Kyriazopoulou, E. Tasouli +45 more
2025Clinical Immunology4 citations Open access
Semantic Scholar
Improving the odds of survival: transgenerational effects of infections
V. Spanou, Theano Andriopoulou, E. Giamarellos-Bourboulis, M. Netea
2025EMBO Molecular Medicine4 citations Open access
Semantic Scholar
Blood culture practices and microbiological capacity for sepsis diagnostics in Europe (2021–2022): a cross-sectional analysis of the European Sepsis Care Survey
Christian S. Scheer, E. Giamarellos-Bourboulis, Djillali Annane, A. Artigas +28 more
2025The Lancet Regional Health - Europe4 citations Open access
Semantic Scholar
Procalcitonin-Guided Early Stop of Antibiotics Prevents Gut Inflammation and Preserves Gut Microbiome: Data from the PROGRESS Controlled Trial.
E. Kyriazopoulou, Emmanouil Stylianakis, G. Damoraki, P. Koufargyris +13 more
2025International Journal of Antimicrobial Agents4 citations
Semantic Scholar
Effects of delayed consent on patient characteristics in adult patients with sepsis
Frank Bloos, H. Bogatsch, M. Netea, E. Giamarellos-Bourboulis +25 more
2024Intensive Care Medicine4 citations Open access
Semantic Scholar
Endotype trajectories: better understanding for better sepsis management.
E. Giamarellos-Bourboulis, M. Bauer, T. E. Sweeney
2026Intensive Care Medicine3 citations
Semantic Scholar
Current status of immunomodulatory therapies in adult sepsis patients: where do we stand?
Dimitra Papatheodosiou, E. Giamarellos-Bourboulis, Christos M. Tsoukas
2026Expert Review of Anti-Infective Therapy3 citations
Semantic Scholar
Regional sepsis care in Catalonia: comparative insights from a secondary analysis of the European Sepsis Care Survey
A. Ceccato, Christian S. Scheer, Ricard Ferrer, M. Martinez +9 more
2025Critical Care3 citations Open access
Semantic Scholar
Standardization of Lesion Classification and Assessment by Investigators in Clinical Trials for Hidradenitis Suppurativa: A Consensus Exercise Using a Modified Delphi Approach.
Amit Garg, A. Strunk, B. Midgette, Kelly Frasier +45 more
2025JAMA dermatology3 citations Open access
Semantic Scholar
Omega-3 Polyunsaturated Fatty Acids in Sepsis: From Prevention to Early Treatment.
E. Giamarellos-Bourboulis
2025Critical Care Medicine3 citations
Semantic Scholar
Author Correction: A consensus immune dysregulation framework for sepsis and critical illnesses
Andrew R. Moore, Hong Zheng, A. Ganesan, Y. Hasin-Brumshtein +24 more
2025Nature Medicine3 citations Open access
Semantic Scholar
29-mRNA host response signatures for classification of bacterial infection, viral infection and disease progression in COVID-19 pneumonia: a post hoc analysis of the SAVE-MORE randomized clinical trial
E. Kyriazopoulou, A. Kotsaki, A. Safarika, Garyfallia Poulakou +37 more
2025Intensive Care Medicine Experimental3 citations Open access
Semantic Scholar

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