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Pyry A. J. Välitalo · SciRah

Researcher profile · Semantic Scholar

Pyry A. J. Välitalo

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Pyry A. J. Välitalo — researcher profile on SciRah

h-index: 13
Works: 22
Citations: 746

Most-cited papers

Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen
A. van Rongen, Pyry A. J. Välitalo, M. Peeters, D. Boerma +5 more
2016Clinical Pharmacokinetics105 citations Open access
Semantic Scholar
Allometric Scaling of Clearance in Paediatric Patients: When Does the Magic of 0.75 Fade?
E. Calvier, E. Krekels, Pyry A. J. Välitalo, A. Rostami-Hodjegan +3 more
2016Clinical Pharmacokinetics102 citations Open access
Semantic Scholar
A Generic Multi-Compartmental CNS Distribution Model Structure for 9 Drugs Allows Prediction of Human Brain Target Site Concentrations
Yumi Yamamoto, Pyry A. J. Välitalo, D. van den Berg, Robin Hartman +14 more
2016Pharmaceutical Research77 citations Open access
Semantic Scholar
Predicting Drug Concentration‐Time Profiles in Multiple CNS Compartments Using a Comprehensive Physiologically‐Based Pharmacokinetic Model
Yumi Yamamoto, Pyry A. J. Välitalo, D. Huntjens, J. Proost +9 more
2017CPT: Pharmacometrics & Systems Pharmacology72 citations Open access
Semantic Scholar
Prediction of human CNS pharmacokinetics using a physiologically‐based pharmacokinetic modeling approach
Yumi Yamamoto, Pyry A. J. Välitalo, Y. Wong, D. Huntjens +9 more
2018European Journal of Pharmaceutical Sciences70 citations Open access
Semantic Scholar
Towards Rational Dosing Algorithms for Vancomycin in Neonates and Infants Based on Population Pharmacokinetic Modeling
Esther J. H. Janssen, Pyry A. J. Välitalo, K. Allegaert, Roosmarijn F. W. de Cock +5 more
2015Antimicrobial Agents and Chemotherapy60 citations Open access
Semantic Scholar
Influence of Morbid Obesity on the Pharmacokinetics of Morphine, Morphine-3-Glucuronide, and Morphine-6-Glucuronide
Sjoerd de Hoogd, Pyry A. J. Välitalo, A. Dahan, S. van Kralingen +4 more
2017Clinical Pharmacokinetics48 citations Open access
Semantic Scholar
Pain and distress caused by endotracheal suctioning in neonates is better quantified by behavioural than physiological items: a comparison based on item response theory modelling
Pyry A. J. Välitalo, M. van Dijk, E. Krekels, S. Gibbins +3 more
2016Pain42 citations
Semantic Scholar
Higher Midazolam Clearance in Obese Adolescents Compared with Morbidly Obese Adults
A. van Rongen, M. J. Brill, J. Vaughns, Pyry A. J. Välitalo +5 more
2017Clinical Pharmacokinetics31 citations Open access
Semantic Scholar
Morphine Glucuronidation and Elimination in Intensive Care Patients: A Comparison with Healthy Volunteers
S. Ahlers, Pyry A. J. Välitalo, M. Peeters, L. van Gulik +4 more
2015Anesthesia and Analgesia24 citations
Semantic Scholar
Drugs Being Eliminated via the Same Pathway Will Not Always Require Similar Pediatric Dose Adjustments
E. Calvier, E. Krekels, Hui-Xin Yu, Pyry A. J. Välitalo +6 more
2018CPT: Pharmacometrics & Systems Pharmacology23 citations Open access
Semantic Scholar
Children in clinical trials: towards evidence-based pediatric pharmacotherapy using pharmacokinetic-pharmacodynamic modeling
J. M. Brussee, E. Calvier, E. Krekels, Pyry A. J. Välitalo +3 more
2016Expert Review of Clinical Pharmacology23 citations Open access
Semantic Scholar
Structure-Based Prediction of Anti-infective Drug Concentrations in the Human Lung Epithelial Lining Fluid
Pyry A. J. Välitalo, K. Griffioen, Matthew L. Rizk, Sandra A. G. Visser +4 more
2015Pharmaceutical Research15 citations Open access
Semantic Scholar
Kernel-Based Visual Hazard Comparison (kbVHC): a Simulation-Free Diagnostic for Parametric Repeated Time-to-Event Models
S. C. Goulooze, Pyry A. J. Välitalo, C. Knibbe, E. Krekels
2017AAPS Journal12 citations Open access
Semantic Scholar
The Influence of Normalization Weight in Population Pharmacokinetic Covariate Models
S. C. Goulooze, S. Völler, Pyry A. J. Välitalo, E. Calvier +3 more
2018Clinical Pharmacokinetics11 citations Open access
Semantic Scholar
When will the Glomerular Filtration Rate in Former Preterm Neonates Catch up with Their Term Peers?
Yunjiao Wu, K. Allegaert, R. Flint, S. C. Goulooze +8 more
2024Pharmaceutical Research10 citations Open access
Semantic Scholar
Body weight, gender and pregnancy affect enantiomer‐specific ketorolac pharmacokinetics
Pyry A. J. Välitalo, Heidi Kemppainen, A. Kulo, A. Smits +5 more
2017British Journal of Clinical Pharmacology10 citations Open access
Semantic Scholar
Dose evaluation of lamivudine in human immunodeficiency virus‐infected children aged 5 months to 18 years based on a population pharmacokinetic analysis
Esther J. H. Janssen, Diane E. T. Bastiaans, Pyry A. J. Välitalo, A. V. van Rossum +4 more
2017British Journal of Clinical Pharmacology8 citations Open access
Semantic Scholar
Predicting Unacceptable Pain in Cardiac Surgery Patients Receiving Morphine Maintenance and Rescue Doses: A Model-Based Pharmacokinetic-Pharmacodynamic Analysis.
S. C. Goulooze, E. Krekels, M. Saleh, S. Ahlers +6 more
2020Anesthesia and Analgesia2 citations Open access
Semantic Scholar
Author’s Reply to Reith: “Morbidly Obese Patients Exhibit Increased CYP2E1-Mediated Oxidation of Acetaminophen”
A. van Rongen, Pyry A. J. Välitalo, C. Knibbe
2018Clinical Pharmacokinetics1 citations
Semantic Scholar
Kernel-Based Visual Hazard Comparison (kbVHC): a Simulation-Free Diagnostic for Parametric Repeated Time-to-Event Models
S. C. Goulooze, Pyry A. J. Välitalo, C. Knibbe, E. Krekels
2017AAPS Journal0 citations Open access
Semantic Scholar
Evaluation of current gentamicin and tobramycin dosing guidelines for neonates
Pyry A. J. Välitalo, K. Allegaert, J. V. van den Anker, Roosmarijn F. W. de Cock +2 more
20140 citations
Semantic Scholar

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