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T. Ramalingam · SciRah

Researcher profile · Semantic Scholar

T. Ramalingam

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T. Ramalingam — researcher profile on SciRah

h-index: 37
Works: 83
Citations: 11K

Most-cited papers

Mechanisms of fibrosis: therapeutic translation for fibrotic disease
T. Wynn, T. Ramalingam
2012Nature Medicine3,408 citations Open access
Semantic Scholar
CD91 is a common receptor for heat shock proteins gp96, hsp90, hsp70, and calreticulin.
S. Basu, R. Binder, T. Ramalingam, P. Srivastava
2001Immunity1,200 citations Open access
Semantic Scholar
Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis
J. Pesce, T. Ramalingam, Margaret M. Mentink-Kane, Mark S. Wilson +6 more
2009PLoS Pathogens831 citations Open access
Semantic Scholar
Bleomycin and IL-1β–mediated pulmonary fibrosis is IL-17A dependent
Mark S. Wilson, S. Madala, T. Ramalingam, B. Gochuico +3 more
2010Journal of Experimental Medicine743 citations Open access
Semantic Scholar
TH2 and TH17 inflammatory pathways are reciprocally regulated in asthma
D. Choy, Kevin M. Hart, L. Borthwick, A. Shikotra +21 more
2015Science Translational Medicine449 citations Open access
Semantic Scholar
The IL-21 receptor augments Th2 effector function and alternative macrophage activation.
J. Pesce, Mallika Kaviratne, T. Ramalingam, Robert W. Thompson +6 more
2006Journal of Clinical Investigation373 citations Open access
Semantic Scholar
Retnla (Relmα/Fizz1) Suppresses Helminth-Induced Th2-Type Immunity
J. Pesce, T. Ramalingam, Mark S. Wilson, Margaret M. Mentink-Kane +4 more
2009PLoS Pathogens233 citations Open access
Semantic Scholar
Unique functions of the type II interleukin 4 receptor identified in mice lacking the interleukin 13 receptor α1 chain
T. Ramalingam, J. Pesce, Faruk G. Sheikh, A. Cheever +9 more
2008Nature Immunology192 citations Open access
Semantic Scholar
Critical role of fatty acid metabolism in ILC2-mediated barrier protection during malnutrition and helminth infection
C. Wilhelm, O. Harrison, V. Schmitt, Martin Pelletier +6 more
2016Journal of Experimental Medicine191 citations Open access
Semantic Scholar
Schistosoma mansoni infection in eosinophil lineage-ablated mice.
J. Swartz, K. Dyer, A. Cheever, T. Ramalingam +7 more
2006Blood186 citations Open access
Semantic Scholar
Combinatorial targeting of TSLP, IL-25, and IL-33 in type 2 cytokine–driven inflammation and fibrosis
K. Vannella, T. Ramalingam, L. Borthwick, L. Barron +9 more
2016Science Translational Medicine182 citations Open access
Semantic Scholar
Analysis of protein-altering variants in telomerase genes and their association with MUC5B common variant status in patients with idiopathic pulmonary fibrosis: a candidate gene sequencing study.
A. Dressen, Alexander R. Abbas, Christopher R. Cabanski, Janina Reeder +19 more
2018The Lancet Respiratory Medicine178 citations Open access
Semantic Scholar
Matrix Metalloproteinase 12-Deficiency Augments Extracellular Matrix Degrading Metalloproteinases and Attenuates IL-13–Dependent Fibrosis
S. Madala, J. Pesce, T. Ramalingam, Mark S. Wilson +5 more
2010Journal of Immunology165 citations Open access
Semantic Scholar
The adaptor protein CIKS/Act1 is essential for IL-25-mediated allergic airway inflammation
E. Claudio, S. U. Sønder, Sun Saret, G. Carvalho +10 more
2009Journal of Immunology157 citations Open access
Semantic Scholar
Macrophages are critical to the maintenance of IL-13-dependent lung inflammation and fibrosis
L. Borthwick, L. Barron, Kevin M. Hart, K. Vannella +7 more
2015Mucosal Immunology135 citations Open access
Semantic Scholar
IL-13Ralpha2 and IL-10 coordinately suppress airway inflammation, airway-hyperreactivity, and fibrosis in mice.
Mark S. Wilson, E. Elnekave, Margaret M. Mentink-Kane, Marcus G. Hodges +8 more
2007Journal of Clinical Investigation133 citations Open access
Semantic Scholar
Type 2 immunity is protective in metabolic disease but exacerbates NAFLD collaboratively with TGF-β
Kevin M. Hart, T. Fabre, J. Sciurba, Richard L. Gieseck +12 more
2017Science Translational Medicine132 citations Open access
Semantic Scholar
Suppression of Murine Allergic Airway Disease by IL-2:Anti-IL-2 Monoclonal Antibody-Induced Regulatory T Cells
Mark S. Wilson, J. Pesce, T. Ramalingam, Robert W. Thompson +2 more
2008Journal of Immunology128 citations Open access
Semantic Scholar
TGFβ2 and TGFβ3 isoforms drive fibrotic disease pathogenesis
Tianhe Sun, Zhiyu Huang, Wei-Ching Liang, Jianping Yin +31 more
2021Science Translational Medicine119 citations Open access
Semantic Scholar
Macrophages as IL-25/IL-33-Responsive Cells Play an Important Role in the Induction of Type 2 Immunity
Zhong-Han Yang, V. Grinchuk, J. Urban, Jennifer A. Bohl +8 more
2013PLoS ONE118 citations Open access
Semantic Scholar
Interleukin-13 activates distinct cellular pathways leading to ductular reaction, steatosis, and fibrosis
Richard L. Gieseck, T. Ramalingam, Kevin M. Hart, K. Vannella +6 more
2016Immunity116 citations Open access
Semantic Scholar
Critical Role of IL-25 in Nematode Infection-Induced Alterations in Intestinal Function
Aiping Zhao, J. Urban, Rex Sun, Jennifer A. Stiltz +8 more
2010Journal of Immunology113 citations Open access
Semantic Scholar
Incomplete Deletion of IL-4Rα by LysMCre Reveals Distinct Subsets of M2 Macrophages Controlling Inflammation and Fibrosis in Chronic Schistosomiasis
K. Vannella, L. Barron, L. Borthwick, Kristen N. Kindrachuk +7 more
2014PLoS Pathogens107 citations Open access
Semantic Scholar
Quantitative Assessment of Macrophage Functions in Repair and Fibrosis
T. Wynn, L. Barron, Robert W. Thompson, S. Madala +3 more
2011Current Protocols in Immunology99 citations Open access
Semantic Scholar
Colitis and intestinal inflammation in IL10−/− mice results from IL-13Rα2-mediated attenuation of IL-13 activity
Mark S. Wilson, T. Ramalingam, Aymeric Rivollier, K. Shenderov +6 more
2010Gastroenterology99 citations Open access
Semantic Scholar
Osteopontin Links Myeloid Activation and Disease Progression in Systemic Sclerosis
Xia Gao, G. Jia, A. Guttman, D. DePianto +10 more
2020Cell Reports Medicine96 citations Open access
Semantic Scholar
TAZ is required for lung alveolar epithelial cell differentiation after injury.
Tianhe Sun, Zhiyu Huang, Hua Zhang, Clara Posner +7 more
2019JCI Insight86 citations Open access
Semantic Scholar
Cationic Amino Acid Transporter-2 Regulates Immunity by Modulating Arginase Activity
Robert W. Thompson, J. Pesce, T. Ramalingam, Mark S. Wilson +7 more
2008PLoS Pathogens86 citations Open access
Semantic Scholar
Critical Role for IgM in Host Protection in Experimental Filarial Infection
B. Rajan, T. Ramalingam, T. Rajan
2005Journal of Immunology82 citations
Semantic Scholar
IL-13 is a therapeutic target in radiation lung injury
S. Chung, J. Horton, T. Ramalingam, Ayla O. White +6 more
2016Scientific Reports66 citations Open access
Semantic Scholar
Accelerated and Progressive and Lethal Liver Fibrosis in Mice that Lack Interleukin (IL)-10, IL-12p40, and IL-13R α2
Margaret M. Mentink-Kane, A. Cheever, Mark S. Wilson, S. Madala +3 more
2011Gastroenterology66 citations Open access
Semantic Scholar
Regulation of Helminth-Induced Th2 Responses by Thymic Stromal Lymphopoietin
T. Ramalingam, J. Pesce, Margaret M. Mentink-Kane, S. Madala +4 more
2009Journal of Immunology58 citations Open access
Semantic Scholar
Acidic chitinase primes the protective immune response to gastrointestinal nematodes
K. Vannella, T. Ramalingam, Kevin M. Hart, Rafael de Queiroz Prado +13 more
2016Nature Immunology57 citations Open access
Semantic Scholar
Enhanced protection from fibrosis and inflammation in the combined absence of IL-13 and IFN-γ
T. Ramalingam, Richard L. Gieseck, Thomas H. Acciani, Kevin M. Hart +4 more
2016Journal of Pathology52 citations Open access
Semantic Scholar
A WISP1 antibody inhibits MRTF signaling to prevent the progression of established liver fibrosis.
Yingmei Xi, Ryan LaCanna, Hsiao-Yen Ma, E. N'Diaye +26 more
2022Cell Metabolism46 citations Open access
Semantic Scholar
IL-33-induced alterations in murine intestinal function and cytokine responses are MyD88, STAT6, and IL-13 dependent.
Zhong-Han Yang, Rex Sun, V. Grinchuk, Joan Antoni Fernandez Blanco +9 more
2013American Journal of Physiology - Gastrointestinal and Liver Physiology42 citations Open access
Semantic Scholar
Exploiting worm and allergy models to understand Th2 cytokine biology
T. Ramalingam, Rachael M Reiman, T. Wynn
2005Current Opinion in Allergy and Clinical Immunology42 citations
Semantic Scholar
IL-13 Receptor α2 Regulates the Immune and Functional Response to Nippostrongylus brasiliensis Infection
M. Morimoto, Aiping Zhao, Rex Sun, Jennifer A. Stiltz +6 more
2009Journal of Immunology37 citations Open access
Semantic Scholar
Kinetics of Cellular Responses to Intraperitoneal Brugia pahangi Infections in Normal and Immunodeficient Mice
T. Ramalingam, B. Rajan, James Lee, T. Rajan
2003Infection and Immunity34 citations Open access
Semantic Scholar
Interleukin-25 or IL-17E protects against high-fat diet-induced hepatic steatosis in mice dependent upon IL-13 activation of STAT6
An-Jiang Wang, Zhong-Han Yang, V. Grinchuk, Allen D. Smith +9 more
2015Journal of Immunology33 citations Open access
Semantic Scholar
Cutting Edge: Eosinophils Undergo Caspase-1–Mediated Pyroptosis in Response to Necrotic Liver Cells
Daphne Palacios-Macapagal, J. Connor, T. Mustelin, T. Ramalingam +2 more
2017Journal of Immunology32 citations Open access
Semantic Scholar
TNFα/IL-17 synergy inhibits IL-13 bioactivity via IL-13Rα2 induction
V. Badalyan, Kezia A. Addo, Robert W. Thompson, L. Borthwick +5 more
2014Journal of Allergy and Clinical Immunology32 citations Open access
Semantic Scholar
Eosinophils, but Not Eosinophil Peroxidase or Major Basic Protein, Are Important for Host Protection in Experimental Brugia pahangi Infection
T. Ramalingam, P. Porte, James Lee, T. Rajan
2005Infection and Immunity31 citations Open access
Semantic Scholar
An interleukin 6 responsive plasma cell signature is associated with disease progression in systemic sclerosis interstitial lung disease
G. Jia, T. Ramalingam, J. V. Heiden, Xia Gao +8 more
2023iScience28 citations Open access
Semantic Scholar
Impaired clearance of primary but not secondary Brugia infections in IL-5 deficient mice.
T. Ramalingam, L. Ganley-Leal, P. Porte, T. Rajan
2003Experimental parasitology28 citations
Semantic Scholar
The IL-13 Receptor-α1 Chain Is Essential for Induction of the Alternative Macrophage Activation Pathway by IL-13 but not IL-4
Faruk G. Sheikh, H. Dickensheets, J. Pedras-Vasconcelos, T. Ramalingam +3 more
2015Journal of Innate Immunity25 citations Open access
Semantic Scholar
Biomarkers of fibrosis, inflammation, and extracellular matrix in the phase 3 trial of tocilizumab in systemic sclerosis.
X. Sheng, Xia Gao, C. Schiffman, Jenny Jiang +4 more
2023Clinical Immunology24 citations Open access
Semantic Scholar
Interleukin-13 Receptor α1-Dependent Responses in the Intestine Are Critical to Parasite Clearance
Rex Sun, J. Urban, L. Notari, Tim Vanuytsel +6 more
2016Infection and Immunity23 citations Open access
Semantic Scholar
Genetic deletion of IL-25 (IL-17E) confers resistance to dextran sulfate sodium-induced colitis in mice
An-Jiang Wang, Allen D. Smith, Yanfei Li, Joseph F. Jr Urban +6 more
2014Cell & Bioscience20 citations Open access
Semantic Scholar
Steroid-induced fibroblast growth factors drive an epithelial-mesenchymal inflammatory axis in severe asthma
R. Guidi, Daqi Xu, D. Choy, T. Ramalingam +21 more
2022Science Translational Medicine14 citations Open access
Semantic Scholar

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