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Shuling Guo · SciRah

Researcher profile · Semantic Scholar

Shuling Guo

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Shuling Guo — researcher profile on SciRah

h-index: 41
Works: 123
Citations: 6,659

Most-cited papers

Targeted delivery of antisense oligonucleotides to hepatocytes using triantennary N-acetyl galactosamine improves potency 10-fold in mice
T. P. Prakash, M. Graham, Jinghua Yu, Rick Carty +16 more
2014Nucleic Acids Research579 citations Open access
Semantic Scholar
Pint lincRNA connects the p53 pathway with epigenetic silencing by the Polycomb repressive complex 2
O. Marin-Bejar, F. Marchese, Alejandro Athie, Yolanda Sánchez +10 more
2013Genome Biology265 citations Open access
Semantic Scholar
An inducible long noncoding RNA amplifies DNA damage signaling
A. Schmitt, Julia T. Garcia, T. Hung, Ryan A. Flynn +10 more
2016Nature Genetics230 citations Open access
Semantic Scholar
Oncogenic Role of THOR, a Conserved Cancer/Testis Long Noncoding RNA
Y. Hosono, Y. Niknafs, J. Prensner, M. Iyer +21 more
2017Cell219 citations Open access
Semantic Scholar
Reducing TMPRSS6 ameliorates hemochromatosis and β-thalassemia in mice.
Shuling Guo, C. Casu, S. Gardenghi, Sheri L. Booten +6 more
2013Journal of Clinical Investigation216 citations Open access
Semantic Scholar
Analysis of the androgen receptor-regulated lncRNA landscape identifies a role for ARLNC1 in prostate cancer progression
Ya-Jia Zhang, S. Pitchiaya, M. Cieslik, Y. Niknafs +33 more
2018Nature Genetics197 citations Open access
Semantic Scholar
Genome-wide analysis of the human p53 transcriptional network unveils a lncRNA tumour suppressor signature
Yolanda Sánchez, V. Segura, O. Marin-Bejar, Alejandro Athie +6 more
2014Nature Communications191 citations Open access
Semantic Scholar
The human lncRNA LINC-PINT inhibits tumor cell invasion through a highly conserved sequence element
O. Marin-Bejar, A. M. Mas, Jovanna González, Dannys Martínez +9 more
2017Genome Biology185 citations Open access
Semantic Scholar
Peripheral androgen receptor gene suppression rescues disease in mouse models of spinal and bulbar muscular atrophy
A. Lieberman, Zhi-Gang Yu, Sue Murray, Raechel Q Peralta +8 more
2014Cell Reports166 citations Open access
Semantic Scholar
Clinical development of an antisense therapy for the treatment of transthyretin-associated polyneuropathy
E. J. Ackermann, Shuling Guo, Sheri L. Booten, Luis Alvarado +3 more
2012Amyloid: Journal of Protein Folding Disorders134 citations
Semantic Scholar
Suppressing transthyretin production in mice, monkeys and humans using 2nd-Generation antisense oligonucleotides
E. J. Ackermann, Shuling Guo, M. Benson, Sheri L. Booten +9 more
2016Amyloid: Journal of Protein Folding Disorders130 citations
Semantic Scholar
Characterization of Target mRNA Reduction Through In Situ RNA Hybridization in Multiple Organ Systems Following Systemic Antisense Treatment in Animals
G. Hung, Xiaokun Xiao, Raechel Q Peralta, G. Bhattacharjee +4 more
2013Nucleic Acid Therapeutics115 citations
Semantic Scholar
Allele-Specific Inhibition of Rhodopsin With an Antisense Oligonucleotide Slows Photoreceptor Cell Degeneration.
S. Murray, A. Jazayeri, M. Matthes, D. Yasumura +10 more
2015Investigative Ophthalmology and Visual Science97 citations Open access
Semantic Scholar
Antisense oligonucleotide treatment ameliorates IFN-γ-induced proteinuria in APOL1-transgenic mice.
M. Aghajan, Sheri L. Booten, M. Althage, Christopher E. Hart +13 more
2019JCI Insight95 citations Open access
Semantic Scholar
A lncRNA-SWI/SNF complex crosstalk controls transcriptional activation at specific promoter regions
Elena Grossi, Ivan Raimondi, Enrique Goñi, Jovanna González +5 more
2020Nature Communications94 citations Open access
Semantic Scholar
Antisense oligonucleotide-mediated Dnm2 knockdown prevents and reverts myotubular myopathy in mice
H. Tasfaout, S. Buono, Shuling Guo, C. Kretz +6 more
2017Nature Communications90 citations Open access
Semantic Scholar
Ligand conjugated antisense oligonucleotide for the treatment of transthyretin amyloidosis: preclinical and phase 1 data
N. Viney, Shuling Guo, Li-Jung Tai, B. Baker +14 more
2020ESC Heart Failure83 citations Open access
Semantic Scholar
Inhaled ENaC antisense oligonucleotide ameliorates cystic fibrosis-like lung disease in mice.
J. Crosby, Chenguang Zhao, Chong Jiang, D. Bai +7 more
2017Journal of Cystic Fibrosis79 citations Open access
Semantic Scholar
Combination of Tmprss6- ASO and the iron chelator deferiprone improves erythropoiesis and reduces iron overload in a mouse model of beta-thalassemia intermedia
C. Casu, M. Aghajan, Paraskevi Rea Oikonomidou, Shuling Guo +2 more
2016Haematologica78 citations Open access
Semantic Scholar
Antisense oligonucleotide treatment ameliorates alpha-1 antitrypsin-related liver disease in mice.
Shuling Guo, Sheri L. Booten, M. Aghajan, G. Hung +8 more
2014Journal of Clinical Investigation74 citations Open access
Semantic Scholar
Chop/Ddit3 depletion in β cells alleviates ER stress and corrects hepatic steatosis in mice
Jing Yong, Vishal S. Parekh, Shannon M. Reilly, Jonamani Nayak +12 more
2021Science Translational Medicine73 citations Open access
Semantic Scholar
Identification and Validation of PCAT14 as Prognostic Biomarker in Prostate Cancer
S. Shukla, Xiang Zhang, Y. Niknafs, Lan-Bo Xiao +15 more
2016Neoplasia67 citations Open access
Semantic Scholar
HOTAIR lncRNA promotes epithelial–mesenchymal transition by redistributing LSD1 at regulatory chromatin regions
Julien Jarroux, Dominika Foretek, C. Bertrand, M. Gabriel +6 more
2021EMBO Reports59 citations Open access
Semantic Scholar
Reducing dynamin 2 (DNM2) rescues DNM2-related dominant centronuclear myopathy
S. Buono, J. Ross, H. Tasfaout, Y. Levy +10 more
2018Proceedings of the National Academy of Sciences of the United States of America59 citations Open access
Semantic Scholar
New approaches to genetic therapies for cystic fibrosis.
A. Boyd, Shuling Guo, Lulu Huang, B. Kerem +3 more
2020Journal of Cystic Fibrosis58 citations Open access
Semantic Scholar
Nonsense Mediated RNA Decay Pathway Inhibition Restores Expression and Function of W1282X CFTR.
M. M. Keenan, Lulu Huang, N. Jordan, E. Wong +8 more
2019American Journal of Respiratory Cell and Molecular Biology57 citations
Semantic Scholar
Transthyretin Antisense Oligonucleotides Lower Circulating RBP4 Levels and Improve Insulin Sensitivity in Obese Mice
L. Zemany, S. Bhanot, O. Peroni, S. Murray +6 more
2014Diabetes54 citations Open access
Semantic Scholar
Antisense suppression of the nonsense mediated decay factor Upf3b as a potential treatment for diseases caused by nonsense mutations
Lulu Huang, Audrey Low, S. Damle, M. M. Keenan +4 more
2018Genome Biology50 citations Open access
Semantic Scholar
Steric Inhibition of 5′ UTR Regulatory Elements Results in Upregulation of Human CFTR
S. Sasaki, Rachel Sun, Huynh-Hoa Bui, J. Crosby +2 more
2019Molecular Therapy46 citations Open access
Semantic Scholar
Correcting β-thalassemia by combined therapies that restrict iron and modulate erythropoietin activity.
C. Casu, M. Pettinato, Alison Liu, M. Aghajan +17 more
2020Blood40 citations Open access
Semantic Scholar
TMPRSS6 as a Therapeutic Target for Disorders of Erythropoiesis and Iron Homeostasis
T. Ganz, E. Nemeth, S. Rivella, Paul W Goldberg +5 more
2023Advances in Therapy38 citations Open access
Semantic Scholar
Novel Targeted Therapy for Precursor B-Cell Acute Lymphoblastic Leukemia: Anti-CD22 Antibody-MXD3 Antisense Oligonucleotide Conjugate
N. Satake, C. Duong, S. Yoshida, Michael E. Oestergaard +10 more
2014Molecular Medicine38 citations Open access
Semantic Scholar
Knockdown of nuclear-retained long noncoding RNAs using modified DNA antisense oligonucleotides.
Xinying Zong, Lulu Huang, Vidisha Tripathi, Raechel Q Peralta +3 more
2015Methods in molecular biology37 citations
Semantic Scholar
Targeting Translation Termination Machinery with Antisense Oligonucleotides for Diseases Caused by Nonsense Mutations
Lulu Huang, M. Aghajan, Tianna Quesenberry, Audrey Low +3 more
2019Nucleic Acid Therapeutics25 citations Open access
Semantic Scholar
MXD3 antisense oligonucleotide with superparamagnetic iron oxide nanoparticles: A new targeted approach for neuroblastoma
S. Yoshida, C. Duong, Michael E. Oestergaard, Michael A. Fazio +8 more
2019Nanomedicine: Nanotechnology, Biology and Medicine25 citations Open access
Semantic Scholar
Partial Hepatectomy Induced Long Noncoding RNA Inhibits Hepatocyte Proliferation during Liver Regeneration
Lulu Huang, S. Damle, Sheri L. Booten, Priyam Singh +9 more
2015PLoS ONE24 citations Open access
Semantic Scholar
The PD-1 with PD-L1 Axis Is Pertinent with the Immune Modulation of Atrial Fibrillation by Regulating T Cell Excitation and Promoting the Secretion of Inflammatory Factors
Guo-Dong Chang, YingWei Chen, Zichang Liu, Yong Wang +3 more
2022Journal of Immunological Research23 citations Open access
Semantic Scholar
CFTR mRNAs with nonsense codons are degraded by the SMG6-mediated endonucleolytic pathway
E. Sanderlin, M. M. Keenan, M. Mense, A. Revenko +3 more
202123 citations Open access
Semantic Scholar
Population pharmacokinetic/pharmacodynamic modelling of eplontersen, an antisense oligonucleotide in development for transthyretin amyloidosis
John K. Diep, R. Yu, N. Viney, E. Schneider +5 more
2022British Journal of Clinical Pharmacology22 citations Open access
Semantic Scholar
Role for Cela1 in Postnatal Lung Remodeling and Alpha‐1 Antitrypsin‐Deficient Emphysema
R. Joshi, A. Heinz, Q. Fan, Shuling Guo +6 more
2018American Journal of Respiratory Cell and Molecular Biology22 citations Open access
Semantic Scholar
The Distinct and Cooperative Roles of Toll-Like Receptor 9 and Receptor for Advanced Glycation End Products in Modulating In Vivo Inflammatory Responses to Select CpG and Non-CpG Oligonucleotides
S. Paz, Jill Hsiao, Patrick Cauntay, Armand Soriano +10 more
2017Nucleic Acid Therapeutics21 citations
Semantic Scholar
Evaluation of Therapeutic Oligonucleotides for Familial Amyloid Polyneuropathy in Patient-Derived Hepatocyte-Like Cells
C. Niemietz, V. Sauer, J. Stella, L. Fleischhauer +9 more
2016PLoS ONE21 citations Open access
Semantic Scholar
Antisense oligonucleotide targeting of mRNAs encoding ENaC subunits α, β, and γ improves cystic fibrosis-like disease in mice.
Chenguang Zhao, J. Crosby, Ting-Hong Lv, D. Bai +2 more
2019Journal of Cystic Fibrosis20 citations Open access
Semantic Scholar
Nucleic Acid Therapies for Cystic Fibrosis
S. Sasaki, Shuling Guo
2017Nucleic Acid Therapeutics20 citations
Semantic Scholar
Using antisense technology to develop a novel therapy for α-1 antitrypsin deficient (AATD) liver disease and to model AATD lung disease
Shuling Guo, Sheri L. Booten, A. Watt, Luis Alvarado +4 more
2014Rare Diseases20 citations Open access
Semantic Scholar
A single approach to targeting transferrin receptor 2 corrects iron and erythropoietic defects in murine models of anemia of inflammation and chronic kidney disease.
V. Olivari, S. D. Di Modica, M. Lidonnici, M. Aghajan +9 more
2023Kidney International18 citations
Semantic Scholar
Antisense oligonucleotides to therapeutically target SARS-CoV-2 infection
Y. Qiao, J. W. Wotring, Charles J. Zhang, Xia Jiang +12 more
2023PLoS ONE17 citations Open access
Semantic Scholar
Tmprss6-ASO as a tool for the treatment of Polycythemia Vera mice
C. Casu, Alison Liu, G. D. De Rosa, Audrey Low +7 more
2021PLoS ONE17 citations Open access
Semantic Scholar
In Vitro and In Vivo Effects of SerpinA1 on the Modulation of Transthyretin Proteolysis
Filipa Bezerra, C. Niemietz, H. Schmidt, A. Zibert +5 more
2021International Journal of Molecular Sciences14 citations Open access
Semantic Scholar
Reversing Antisense Oligonucleotide Activity with a Sense Oligonucleotide Antidote: Proof of Concept Targeting Prothrombin
Jeffrey R. Crosby, Chenguang Zhao, Hong Zhang, A. Macleod +2 more
2015Nucleic Acid Therapeutics14 citations
Semantic Scholar

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