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J. Corbin · SciRah

Researcher profile · Semantic Scholar

J. Corbin

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J. Corbin — researcher profile on SciRah

h-index: 15
Works: 23
Citations: 933

Most-cited papers

Targeting CD39 in cancer reveals an extracellular ATP and inflammasome driven tumor immunity
Xian-Yang Li, Achim K. Moesta, Christos Xiao, Kyohei Nakamura +26 more
2019Cancer Discovery234 citations Open access
Semantic Scholar
Mechanism of specific membrane targeting by C2 domains: localized pools of target lipids enhance Ca2+ affinity.
J. Corbin, J. H. Evans, K. Landgraf, J. Falke
2007Biochemistry101 citations Open access
Semantic Scholar
XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1β-mediated diseases
Alexander M. Owyang, H. Issafras, J. Corbin, Kiran Ahluwalia +7 more
2011mAbs88 citations Open access
Semantic Scholar
GRP1 pleckstrin homology domain: activation parameters and novel search mechanism for rare target lipid.
J. Corbin, R. Dirkx, J. Falke
2004Biochemistry87 citations Open access
Semantic Scholar
A Fully Human, Allosteric Monoclonal Antibody That Activates the Insulin Receptor and Improves Glycemic Control
V. Bhaskar, I. Goldfine, Daniel H. Bedinger, A. Lau +19 more
2012Diabetes71 citations Open access
Semantic Scholar
Detailed Mechanistic Analysis of Gevokizumab, an Allosteric Anti–IL-1β Antibody with Differential Receptor-Modulating Properties
H. Issafras, J. Corbin, I. Goldfine, M. Roell
2014Journal of Pharmacology and Experimental Therapeutics47 citations Open access
Semantic Scholar
Fully human anti-CD39 antibody potently inhibits ATPase activity in cancer cells via uncompetitive allosteric mechanism
Bradley N. Spatola, Alana G. Lerner, Clifford Wong, T. Dela Cruz +8 more
2020mAbs45 citations Open access
Semantic Scholar
Kinetic Approach to Pathway Attenuation Using XOMA 052, a Regulatory Therapeutic Antibody That Modulates Interleukin-1β Activity
M. Roell, H. Issafras, R. Bauer, Kristen S. Michelson +17 more
2010Journal of Biological Chemistry44 citations Open access
Semantic Scholar
Improved gas chromatographic separations of enantiomeric secondary amine derivatives
J. Corbin, L. Rogers
197037 citations Open access
Semantic Scholar
Effects of structure of peptide stationary phases on gas chromatographic separations of amino acid enantiomers.
J. Corbin, J. Rhoad, L. Rogers
1971Analytical Chemistry36 citations Open access
Semantic Scholar
Membrane Docking Geometry of GRP1 PH Domain Bound to a Target Lipid Bilayer: An EPR Site-Directed Spin-Labeling and Relaxation Study
Huai-Chun Chen, B. Ziemba, K. Landgraf, J. Corbin +1 more
2012PLoS ONE27 citations Open access
Semantic Scholar
Differential Pathway Coupling of the Activated Insulin Receptor Drives Signaling Selectivity by XMetA, an Allosteric Partial Agonist Antibody
Daniel H. Bedinger, I. Goldfine, J. Corbin, M. Roell +1 more
2015Journal of Pharmacology and Experimental Therapeutics23 citations Open access
Semantic Scholar
Selective Allosteric Antibodies to the Insulin Receptor for the Treatment of Hyperglycemic and Hypoglycemic Disorders
H. Issafras, Daniel H. Bedinger, J. Corbin, I. Goldfine +4 more
2014Journal of Diabetes Science and Technology23 citations Open access
Semantic Scholar
Improved Glucose Metabolism In Vitro and In Vivo by an Allosteric Monoclonal Antibody That Increases Insulin Receptor Binding Affinity
J. Corbin, V. Bhaskar, I. Goldfine, Daniel H. Bedinger +21 more
2014PLoS ONE20 citations Open access
Semantic Scholar
A unique allosteric insulin receptor monoclonal antibody that prevents hypoglycemia in the SUR-1−/− mouse model of KATP hyperinsulinism
Puja Patel, L. Charles, J. Corbin, I. Goldfine +3 more
2018mAbs16 citations Open access
Semantic Scholar
Affinity Tags for Protein Purification
J. Falke, J. Corbin
200410 citations
Semantic Scholar
Separations of enantiomeric derivatives of amines and amino acids by adsorption chromatography.
J. Corbin, L. Rogers
1970Analytical Chemistry9 citations Open access
Semantic Scholar
An allosteric antibody to the leptin receptor reduces body weight and reverses the diabetic phenotype in the Lepob/Lepob mouse
V. Bhaskar, I. Goldfine, R. Gerstner, Kristen S. Michelson +9 more
2016Obesity8 citations
Semantic Scholar
Abstract 5012: Targeting CD39 with a first-in-class inhibitory antibody prevents ATP processing and increases T-cell activation
Alana G. Lerner, Maria I. Kovalenko, M. Welch, T. D. Cruz +13 more
2019Immunology4 citations
Semantic Scholar
698 Targeting HLA-G-mediated immunosuppression with a first-in-class antagonist antibody
D. Hodges, Christina M. Kochel, Michael Totagrande, Jeffrey A. Jones +7 more
20202 citations Open access
Semantic Scholar
Sa.56. Efficacy Of XOMA 052 Anti-IL-1β Antibody In The DBA/1 Mouse Collagen-Induced Arthritis Model
Alexander M. Owyang, L. Esposito, Sandra Vanegas, L. Masat +10 more
20082 citations
Semantic Scholar
XMetS potentiates insulin-dependent Akt and Erk phosphorylation.
J. Corbin, V. Bhaskar, I. Goldfine, Daniel H. Bedinger +21 more
20140 citations Open access
Semantic Scholar
Structural Analysis of the Membrane Docking Geometry of PI(3,4,5)P3-Specific GRP1-PH Domain Via Site-Directed Spin Labeling
Zachary J. Owens, K. Landgraf, J. Corbin, Danielle C. Dukellis +1 more
20100 citations Open access
Semantic Scholar

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