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S. Mairinger · SciRah

Researcher profile · Semantic Scholar

S. Mairinger

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S. Mairinger — researcher profile on SciRah

h-index: 20
Works: 83
Citations: 1,225

Most-cited papers

Synthesis and in vivo evaluation of [11C]tariquidar, a positron emission tomography radiotracer based on a third-generation P-glycoprotein inhibitor
Florian Bauer, C. Kuntner, J. Bankstahl, T. Wanek +8 more
2010Bioorganic & Medicinal Chemistry80 citations Open access
Semantic Scholar
Design, Synthesis, and Evaluation of a Low-Molecular-Weight (11)C-Labeled Tetrazine for Pretargeted PET Imaging Applying Bioorthogonal in Vivo Click Chemistry.
C. Denk, D. Svatunek, S. Mairinger, J. Stanek +5 more
2016Bioconjugate chemistry76 citations
Semantic Scholar
PET and SPECT Radiotracers to Assess Function and Expression of ABC Transporters in Vivo
S. Mairinger, T. Erker, M. Müller, O. Langer
2011Current drug metabolism75 citations Open access
Semantic Scholar
Synthesis and small-animal positron emission tomography evaluation of [11C]-elacridar as a radiotracer to assess the distribution of P-glycoprotein at the blood-brain barrier
Bernd Dörner, C. Kuntner, J. Bankstahl, M. Bankstahl +8 more
2009Journal of Medicinal Chemistry74 citations Open access
Semantic Scholar
A Novel PET Protocol for Visualization of Breast Cancer Resistance Protein Function at the Blood–Brain Barrier
T. Wanek, C. Kuntner, J. Bankstahl, S. Mairinger +8 more
2012Journal of Cerebral Blood Flow and Metabolism59 citations Open access
Semantic Scholar
Breast Cancer Resistance Protein and P-Glycoprotein Influence In Vivo Disposition of 11C-Erlotinib
A. Traxl, T. Wanek, S. Mairinger, J. Stanek +5 more
2015Journal of Nuclear Medicine57 citations Open access
Semantic Scholar
Strategies to Inhibit ABCB1- and ABCG2-Mediated Efflux Transport of Erlotinib at the Blood–Brain Barrier: A PET Study on Nonhuman Primates
N. Tournier, S. Goutal, Sylvain Auvity, A. Traxl +7 more
2017Journal of Nuclear Medicine52 citations Open access
Semantic Scholar
Radioligands targeting P-glycoprotein and other drug efflux proteins at the blood-brain barrier.
T. Wanek, S. Mairinger, O. Langer
2013Journal of labelled compounds & radiopharmaceuticals47 citations Open access
Semantic Scholar
Factors Governing P-Glycoprotein-Mediated Drug–Drug Interactions at the Blood–Brain Barrier Measured with Positron Emission Tomography
T. Wanek, K. Römermann, S. Mairinger, J. Stanek +10 more
2015Molecular Pharmaceutics43 citations Open access
Semantic Scholar
Imaging P-Glycoprotein Induction at the Blood–Brain Barrier of a β-Amyloidosis Mouse Model with 11C-Metoclopramide PET
V. Zoufal, S. Mairinger, M. Brackhan, M. Krohn +8 more
2019Journal of Nuclear Medicine32 citations Open access
Semantic Scholar
Radiosynthesis and in vivo evaluation of 1-[18F]fluoroelacridar as a positron emission tomography tracer for P-glycoprotein and breast cancer resistance protein
Bernd Dörner, C. Kuntner, J. Bankstahl, T. Wanek +11 more
2011Bioorganic & Medicinal Chemistry31 citations Open access
Semantic Scholar
A comparative small-animal PET evaluation of [11C]tariquidar, [11C]elacridar and (R)-[11C]verapamil for detection of P-glycoprotein expressing murine breast cancer
T. Wanek, C. Kuntner, J. Bankstahl, M. Bankstahl +9 more
2011European Journal of Nuclear Medicine and Molecular Imaging30 citations Open access
Semantic Scholar
Inhibition of ABCB1 and ABCG2 at the Mouse Blood-Brain Barrier with Marketed Drugs To Improve Brain Delivery of the Model ABCB1/ABCG2 Substrate [11C]erlotinib.
A. Traxl, S. Mairinger, T. Filip, M. Sauberer +9 more
2019Molecular Pharmaceutics26 citations
Semantic Scholar
Complete inhibition of ABCB1 and ABCG2 at the blood–brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [11C]erlotinib
N. Tournier, S. Goutal, S. Mairinger, Irene Hernández-Lozano +10 more
2020Journal of Cerebral Blood Flow and Metabolism24 citations Open access
Semantic Scholar
Measurement of cerebral ABCC1 transport activity in wild-type and APP/PS1-21 mice with positron emission tomography
V. Zoufal, S. Mairinger, M. Krohn, T. Wanek +6 more
2020Journal of Cerebral Blood Flow and Metabolism22 citations Open access
Semantic Scholar
Assessing the Activity of Multidrug Resistance–Associated Protein 1 at the Lung Epithelial Barrier
S. Mairinger, J. A. Sake, I. H. Lozano, T. Filip +5 more
2020Journal of Nuclear Medicine21 citations Open access
Semantic Scholar
Age dependency of cerebral P-glycoprotein function in wild-type and APPPS1 mice measured with PET
V. Zoufal, T. Wanek, M. Krohn, S. Mairinger +7 more
2018Journal of Cerebral Blood Flow and Metabolism21 citations Open access
Semantic Scholar
Preclinical in vitro &in vivo evaluation of [(11)C]SNAP-7941 - the first PET tracer for the melanin concentrating hormone receptor 1.
C. Philippe, L. Nics, M. Zeilinger, C. Kuntner +7 more
2013Nuclear Medicine and Biology21 citations
Semantic Scholar
Assessment of cerebral P-glycoprotein expression and function with PET by combined [11C]inhibitor and [11C]substrate scans in rats.
Julia Müllauer, R. Karch, J. Bankstahl, M. Bankstahl +7 more
2013Nuclear Medicine and Biology20 citations Open access
Semantic Scholar
Synthesis and preclinical evaluation of the radiolabeled P-glycoprotein inhibitor [11C]MC113
S. Mairinger, T. Wanek, C. Kuntner, Yaprak Doenmez +7 more
2012Nuclear Medicine and Biology20 citations Open access
Semantic Scholar
Measurement of hepatic ABCB1 and ABCG2 transport activity with [11C]tariquidar and PET in humans and mice.
Irene Hernández Lozano, M. Bauer, B. Wulkersdorfer, A. Traxl +10 more
2019Molecular Pharmaceutics19 citations Open access
Semantic Scholar
On the applicability of [18F]FBPA to predict L-BPA concentration after amino acid preloading in HuH-7 liver tumor model and the implication for liver boron neutron capture therapy.
Catrin Grunewald, M. Sauberer, T. Filip, T. Wanek +8 more
2017Nuclear Medicine and Biology19 citations
Semantic Scholar
Development of Fluorine-18 Labeled Metabolically Activated Tracers for Imaging of Drug Efflux Transporters with Positron Emission Tomography.
K. Sander, E. Galante, Thibault Gendron, E. Yiannaki +20 more
2015Journal of Medicinal Chemistry19 citations Open access
Semantic Scholar
Influence of Multidrug Resistance-Associated Proteins on the Excretion of the ABCC1 Imaging Probe 6-Bromo-7-[11C]Methylpurine in Mice
V. Zoufal, S. Mairinger, M. Krohn, T. Wanek +8 more
2018Molecular Imaging and Biology17 citations Open access
Semantic Scholar
PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats.
Irene Hernández-Lozano, S. Mairinger, T. Filip, M. Sauberer +6 more
2021Journal of Controlled Release16 citations Open access
Semantic Scholar
Nuclear medicine imaging methods as novel tools in the assessment of pulmonary drug disposition
S. Mairinger, Irene Hernández-Lozano, M. Zeitlinger, C. Ehrhardt +1 more
2022Expert Opinion on Drug Delivery14 citations Open access
Semantic Scholar
Preloading with L-BPA, L-tyrosine and L-DOPA enhances the uptake of [18F]FBPA in human and mouse tumour cell lines.
B. Wingelhofer, Katharina Kreis, S. Mairinger, Viktoria E Muchitsch +4 more
2016Applied Radiation and Isotopes14 citations
Semantic Scholar
The antiepileptic drug mephobarbital is not transported by P-glycoprotein or multidrug resistance protein 1 at the blood-brain barrier: a positron emission tomography study
S. Mairinger, J. Bankstahl, C. Kuntner, K. Römermann +7 more
2012Epilepsy Research14 citations Open access
Semantic Scholar
Synthesis and preclinical characterization of 1-(6'-deoxy-6'-[18F]fluoro-β-d-allofuranosyl)-2-nitroimidazole (β-6'-[18F]FAZAL) as a positron emission tomography radiotracer to assess tumor hypoxia.
T. Wanek, Katharina Kreis, P. Křížková, A. Schweifer +14 more
2016Bioorganic & Medicinal Chemistry13 citations
Semantic Scholar
Synthesis and in vivo evaluation of the putative breast cancer resistance protein inhibitor [11C]methyl 4-((4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)phenyl)amino-carbonyl)-2-(quinoline-2-carbonylamino)benzoate
S. Mairinger, O. Langer, C. Kuntner, T. Wanek +9 more
2010Nuclear Medicine and Biology13 citations Open access
Semantic Scholar
Impact of P-gp and BCRP on pulmonary drug disposition assessed by PET imaging in rats.
S. Mairinger, Irene Hernández-Lozano, T. Filip, M. Sauberer +7 more
2022Journal of Controlled Release12 citations Open access
Semantic Scholar
Hepatocyte-Specific Deletion of EGFR in Mice Reduces Hepatic Abcg2 Transport Activity Measured by [11C]erlotinib and Positron Emission Tomography
A. Traxl, K. Komposch, E. Glitzner, T. Wanek +3 more
2017Drug Metabolism And Disposition12 citations Open access
Semantic Scholar
[18F]Fluoroalkyl azides for rapid radiolabeling and (Re)investigation of their potential towards in vivo click chemistry.
C. Denk, M. Wilkovitsch, Philipp Skrinjar, D. Svatunek +6 more
2017Organic and biomolecular chemistry12 citations Open access
Semantic Scholar
Automated electrophilic radiosynthesis of [¹⁸F]FBPA using a modified nucleophilic GE TRACERlab FXFDG.
S. Mairinger, J. Stanek, T. Wanek, O. Langer +1 more
2015Applied Radiation and Isotopes12 citations
Semantic Scholar
Influence of ABC transporters on the excretion of ciprofloxacin assessed with PET imaging in mice.
Irene Hernández-Lozano, T. Wanek, M. Sauberer, T. Filip +6 more
2021European Journal of Pharmaceutical Sciences11 citations Open access
Semantic Scholar
Comparison of fully-automated radiosyntheses of [11C]erlotinib for preclinical and clinical use starting from in target produced [11C]CO2 or [11C]CH4
C. Philippe, S. Mairinger, V. Pichler, J. Stanek +6 more
2018EJNMMI Radiopharmacy and Chemistry11 citations Open access
Semantic Scholar
Assessing the Functional Redundancy between P-gp and BCRP in Controlling the Brain Distribution and Biliary Excretion of Dual Substrates with PET Imaging in Mice
Irene Hernández-Lozano, S. Mairinger, A. Traxl, M. Sauberer +5 more
2021Pharmaceutics10 citations Open access
Semantic Scholar
Interaction of HM30181 with P-glycoprotein at the murine blood-brain barrier assessed with positron emission tomography
Florian Bauer, T. Wanek, S. Mairinger, J. Stanek +7 more
2012European Journal of Pharmacology10 citations Open access
Semantic Scholar
Influence of P-glycoprotein on pulmonary disposition of the model substrate [11C]metoclopramide assessed by PET imaging in rats.
S. Mairinger, Irene Hernández-Lozano, T. Filip, Mathilde Löbsch +7 more
2023European Journal of Pharmaceutical Sciences9 citations Open access
Semantic Scholar
Characterization of an APP/tau rat model of Alzheimer’s disease by positron emission tomography and immunofluorescent labeling
T. Filip, S. Mairinger, J. Neddens, M. Sauberer +7 more
2021Alzheimer's Research & Therapy9 citations Open access
Semantic Scholar
Generation and Characterization of an Abcc1 Humanized Mouse Model (hABCC1flx/flx) with Knockout Capability
M. Krohn, V. Zoufal, S. Mairinger, T. Wanek +6 more
2019Molecular Pharmacology9 citations Open access
Semantic Scholar
Knockout of ABCC1 in NCI-H441 cells reveals CF to be a suboptimal substrate to study MRP1 activity in organotypic in vitro models.
J. A. Sake, M. A. Selo, Lyubomyr Burtnyak, Henriette E. Dähnhardt +5 more
2022European Journal of Pharmaceutical Sciences8 citations Open access
Semantic Scholar
In vivo characterization of [18F]AVT-011 as a radiotracer for PET imaging of multidrug resistance
P. Kannan, András Füredi, S. Dizdarevic, T. Wanek +8 more
2019European Journal of Nuclear Medicine and Molecular Imaging8 citations Open access
Semantic Scholar
Cross‐Isotopic Bioorthogonal Tools as Molecular Twins for Radiotheranostic Applications
V. Rosecker, C. Denk, M. Maurer, M. Wilkovitsch +3 more
2019ChemBioChem8 citations Open access
Semantic Scholar
[11C]Erlotinib PET cannot detect acquired erlotinib resistance in NSCLC tumor xenografts in mice.
A. Traxl, Taraneh Beikbaghban, T. Wanek, K. Kryeziu +8 more
2017Nuclear Medicine and Biology8 citations
Semantic Scholar
Influence of 24-Nor-Ursodeoxycholic Acid on Hepatic Disposition of [(18)F]Ciprofloxacin, a Positron Emission Tomography Study in Mice.
T. Wanek, E. Halilbasic, M. Visentin, S. Mairinger +6 more
2016Journal of Pharmacy and Science8 citations
Semantic Scholar
[11C]Metoclopramide PET can detect a seizure-induced up-regulation of cerebral P-glycoprotein in epilepsy patients
Myriam El Biali, Louise Breuil, Matthias Jackwerth, S. Mairinger +13 more
2024Fluids and Barriers of the CNS7 citations Open access
Semantic Scholar
Brain Distribution of Dual ABCB1/ABCG2 Substrates Is Unaltered in a Beta-Amyloidosis Mouse Model
T. Wanek, V. Zoufal, M. Brackhan, M. Krohn +7 more
2020International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
St. John's wort extract with a high hyperforin content does not induce P‐glycoprotein activity at the human blood–brain barrier
Myriam El Biali, M. Wölfl-Duchek, Matthias Jackwerth, S. Mairinger +13 more
2024Clinical and Translational Science6 citations Open access
Semantic Scholar
Positron Emission Tomography-Based Pharmacokinetic Analysis To Assess Renal Transporter-Mediated Drug-Drug Interactions of Antimicrobial Drugs
Irene Hernández-Lozano, S. Mairinger, T. Filip, Mathilde Löbsch +8 more
2023Antimicrobial Agents and Chemotherapy6 citations Open access
Semantic Scholar

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J. Stanek×35
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C. Kuntner×27
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T. Filip — researcher profile on SciRah

M. Sauberer×21

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M. Müller — researcher profile on SciRah

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A. Traxl — researcher profile on SciRah

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