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J. Stanek · SciRah

Researcher profile · Semantic Scholar

J. Stanek

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J. Stanek — researcher profile on SciRah

h-index: 23
Works: 87
Citations: 1,883

Most-cited papers

Dose-response assessment of tariquidar and elacridar and regional quantification of P-glycoprotein inhibition at the rat blood-brain barrier using (R)-[11C]verapamil PET
C. Kuntner, J. Bankstahl, M. Bankstahl, J. Stanek +9 more
2009European Journal of Nuclear Medicine and Molecular Imaging126 citations Open access
Semantic Scholar
P-glycoprotein mediated interaction between (R)-[11C]verapamil and tariquidar at the human blood-brain barrier studied with positron emission tomography, a comparison with rat data
M. Bauer, M. Zeitlinger, R. Karch, P. Matzneller +11 more
2011Clinical pharmacology and therapy117 citations Open access
Semantic Scholar
Tariquidar and Elacridar Are Dose-Dependently Transported by P-Glycoprotein and Bcrp at the Blood-Brain Barrier: A Small-Animal Positron Emission Tomography and In Vitro Study
J. Bankstahl, M. Bankstahl, K. Römermann, T. Wanek +8 more
2013Drug Metabolism And Disposition110 citations
Semantic Scholar
Tariquidar-induced P-glycoprotein inhibition at the rat blood-brain barrier studied with (R)-11C-verapamil and PET
J. Bankstahl, C. Kuntner, A. Abrahim, R. Karch +7 more
2008Journal of Nuclear Medicine109 citations Open access
Semantic Scholar
Limitations of Small Animal PET Imaging with [18F]FDDNP and FDG for Quantitative Studies in a Transgenic Mouse Model of Alzheimer’s Disease
C. Kuntner, A. Kesner, M. Bauer, Robert Kremslehner +7 more
2009Molecular Imaging and Biology99 citations
Semantic Scholar
Approaching complete inhibition of P-glycoprotein at the human blood–brain barrier: an (R)-[11C]verapamil PET study
M. Bauer, R. Karch, M. Zeitlinger, C. Philippe +8 more
2015Journal of Cerebral Blood Flow and Metabolism91 citations Open access
Semantic Scholar
Synthesis and in vivo evaluation of [11C]tariquidar, a positron emission tomography radiotracer based on a third-generation P-glycoprotein inhibitor
Florian Bauer, C. Kuntner, J. Bankstahl, T. Wanek +8 more
2010Bioorganic & Medicinal Chemistry80 citations Open access
Semantic Scholar
Design, Synthesis, and Evaluation of a Low-Molecular-Weight (11)C-Labeled Tetrazine for Pretargeted PET Imaging Applying Bioorthogonal in Vivo Click Chemistry.
C. Denk, D. Svatunek, S. Mairinger, J. Stanek +5 more
2016Bioconjugate chemistry76 citations
Semantic Scholar
Synthesis and small-animal positron emission tomography evaluation of [11C]-elacridar as a radiotracer to assess the distribution of P-glycoprotein at the blood-brain barrier
Bernd Dörner, C. Kuntner, J. Bankstahl, M. Bankstahl +8 more
2009Journal of Medicinal Chemistry74 citations Open access
Semantic Scholar
A novel PET imaging protocol identifies seizure-induced regional overactivity of P-glycoprotein at the blood-brain barrier
J. Bankstahl, M. Bankstahl, C. Kuntner, J. Stanek +6 more
2011Journal of Neuroscience63 citations Open access
Semantic Scholar
Pilot PET Study to Assess the Functional Interplay Between ABCB1 and ABCG2 at the Human Blood–Brain Barrier
M. Bauer, K. Römermann, R. Karch, B. Wulkersdorfer +11 more
2016Clinical pharmacology and therapy61 citations Open access
Semantic Scholar
A Novel PET Protocol for Visualization of Breast Cancer Resistance Protein Function at the Blood–Brain Barrier
T. Wanek, C. Kuntner, J. Bankstahl, S. Mairinger +8 more
2012Journal of Cerebral Blood Flow and Metabolism59 citations Open access
Semantic Scholar
Breast Cancer Resistance Protein and P-Glycoprotein Influence In Vivo Disposition of 11C-Erlotinib
A. Traxl, T. Wanek, S. Mairinger, J. Stanek +5 more
2015Journal of Nuclear Medicine57 citations Open access
Semantic Scholar
P-Glycoprotein and Breast Cancer Resistance Protein at the Human Blood-Brain Barrier
M. Bauer, R. Karch, M. Zeitlinger, J. Stanek +6 more
201354 citations
Semantic Scholar
Influence of OATPs on Hepatic Disposition of Erlotinib Measured With Positron Emission Tomography
M. Bauer, A. Matsuda, B. Wulkersdorfer, C. Philippe +14 more
2017Clinical pharmacology and therapy48 citations Open access
Semantic Scholar
Factors Governing P-Glycoprotein-Mediated Drug–Drug Interactions at the Blood–Brain Barrier Measured with Positron Emission Tomography
T. Wanek, K. Römermann, S. Mairinger, J. Stanek +10 more
2015Molecular Pharmaceutics43 citations Open access
Semantic Scholar
Imaging P-Glycoprotein Induction at the Blood–Brain Barrier of a β-Amyloidosis Mouse Model with 11C-Metoclopramide PET
V. Zoufal, S. Mairinger, M. Brackhan, M. Krohn +8 more
2019Journal of Nuclear Medicine32 citations Open access
Semantic Scholar
Effect of P‐glycoprotein inhibition at the blood–brain barrier on brain distribution of (R)‐[11C]verapamil in elderly vs. young subjects
M. Bauer, B. Wulkersdorfer, R. Karch, C. Philippe +6 more
2017British Journal of Clinical Pharmacology32 citations Open access
Semantic Scholar
Radiosynthesis and in vivo evaluation of 1-[18F]fluoroelacridar as a positron emission tomography tracer for P-glycoprotein and breast cancer resistance protein
Bernd Dörner, C. Kuntner, J. Bankstahl, T. Wanek +11 more
2011Bioorganic & Medicinal Chemistry31 citations Open access
Semantic Scholar
A comparative small-animal PET evaluation of [11C]tariquidar, [11C]elacridar and (R)-[11C]verapamil for detection of P-glycoprotein expressing murine breast cancer
T. Wanek, C. Kuntner, J. Bankstahl, M. Bankstahl +9 more
2011European Journal of Nuclear Medicine and Molecular Imaging30 citations Open access
Semantic Scholar
Inhibition of ABCB1 and ABCG2 at the Mouse Blood-Brain Barrier with Marketed Drugs To Improve Brain Delivery of the Model ABCB1/ABCG2 Substrate [11C]erlotinib.
A. Traxl, S. Mairinger, T. Filip, M. Sauberer +9 more
2019Molecular Pharmaceutics26 citations
Semantic Scholar
Plasma protein binding may reduce antimicrobial activity by preventing intra-bacterial uptake of antibiotics, for example clindamycin.
A. Burian, C. Wagner, J. Stanek, Mohammad Manafi +3 more
2011Journal of Antimicrobial Chemotherapy25 citations Open access
Semantic Scholar
Complete inhibition of ABCB1 and ABCG2 at the blood–brain barrier by co-infusion of erlotinib and tariquidar to improve brain delivery of the model ABCB1/ABCG2 substrate [11C]erlotinib
N. Tournier, S. Goutal, S. Mairinger, Irene Hernández-Lozano +10 more
2020Journal of Cerebral Blood Flow and Metabolism24 citations Open access
Semantic Scholar
Measurement of cerebral ABCC1 transport activity in wild-type and APP/PS1-21 mice with positron emission tomography
V. Zoufal, S. Mairinger, M. Krohn, T. Wanek +6 more
2020Journal of Cerebral Blood Flow and Metabolism22 citations Open access
Semantic Scholar
Assessing the Activity of Multidrug Resistance–Associated Protein 1 at the Lung Epithelial Barrier
S. Mairinger, J. A. Sake, I. H. Lozano, T. Filip +5 more
2020Journal of Nuclear Medicine21 citations Open access
Semantic Scholar
Age dependency of cerebral P-glycoprotein function in wild-type and APPPS1 mice measured with PET
V. Zoufal, T. Wanek, M. Krohn, S. Mairinger +7 more
2018Journal of Cerebral Blood Flow and Metabolism21 citations Open access
Semantic Scholar
Assessment of cerebral P-glycoprotein expression and function with PET by combined [11C]inhibitor and [11C]substrate scans in rats.
Julia Müllauer, R. Karch, J. Bankstahl, M. Bankstahl +7 more
2013Nuclear Medicine and Biology20 citations Open access
Semantic Scholar
Synthesis and preclinical evaluation of the radiolabeled P-glycoprotein inhibitor [11C]MC113
S. Mairinger, T. Wanek, C. Kuntner, Yaprak Doenmez +7 more
2012Nuclear Medicine and Biology20 citations Open access
Semantic Scholar
On the applicability of [18F]FBPA to predict L-BPA concentration after amino acid preloading in HuH-7 liver tumor model and the implication for liver boron neutron capture therapy.
Catrin Grunewald, M. Sauberer, T. Filip, T. Wanek +8 more
2017Nuclear Medicine and Biology19 citations
Semantic Scholar
Development of Fluorine-18 Labeled Metabolically Activated Tracers for Imaging of Drug Efflux Transporters with Positron Emission Tomography.
K. Sander, E. Galante, Thibault Gendron, E. Yiannaki +20 more
2015Journal of Medicinal Chemistry19 citations Open access
Semantic Scholar
Influence of Multidrug Resistance-Associated Proteins on the Excretion of the ABCC1 Imaging Probe 6-Bromo-7-[11C]Methylpurine in Mice
V. Zoufal, S. Mairinger, M. Krohn, T. Wanek +8 more
2018Molecular Imaging and Biology17 citations Open access
Semantic Scholar
PET imaging to assess the impact of P-glycoprotein on pulmonary drug delivery in rats.
Irene Hernández-Lozano, S. Mairinger, T. Filip, M. Sauberer +6 more
2021Journal of Controlled Release16 citations Open access
Semantic Scholar
Development and performance test of an online blood sampling system for determination of the arterial input function in rats
F. Roehrbacher, J. Bankstahl, M. Bankstahl, T. Wanek +6 more
2015EJNMMI Physics16 citations Open access
Semantic Scholar
Synthesis of a [18F]fluorobenzothiazole as potential amyloid imaging agent
Ursula E. Ch. Berndt, Christian Stanetty, T. Wanek, C. Kuntner +8 more
200816 citations
Semantic Scholar
Preloading with L-BPA, L-tyrosine and L-DOPA enhances the uptake of [18F]FBPA in human and mouse tumour cell lines.
B. Wingelhofer, Katharina Kreis, S. Mairinger, Viktoria E Muchitsch +4 more
2016Applied Radiation and Isotopes14 citations
Semantic Scholar
The antiepileptic drug mephobarbital is not transported by P-glycoprotein or multidrug resistance protein 1 at the blood-brain barrier: a positron emission tomography study
S. Mairinger, J. Bankstahl, C. Kuntner, K. Römermann +7 more
2012Epilepsy Research14 citations Open access
Semantic Scholar
Synthesis and preclinical characterization of 1-(6'-deoxy-6'-[18F]fluoro-β-d-allofuranosyl)-2-nitroimidazole (β-6'-[18F]FAZAL) as a positron emission tomography radiotracer to assess tumor hypoxia.
T. Wanek, Katharina Kreis, P. Křížková, A. Schweifer +14 more
2016Bioorganic & Medicinal Chemistry13 citations
Semantic Scholar
Synthesis and in vivo evaluation of the putative breast cancer resistance protein inhibitor [11C]methyl 4-((4-(2-(6,7-dimethoxy-1,2,3,4-tetrahydroisoquinolin-2-yl)ethyl)phenyl)amino-carbonyl)-2-(quinoline-2-carbonylamino)benzoate
S. Mairinger, O. Langer, C. Kuntner, T. Wanek +9 more
2010Nuclear Medicine and Biology13 citations Open access
Semantic Scholar
Impact of P-gp and BCRP on pulmonary drug disposition assessed by PET imaging in rats.
S. Mairinger, Irene Hernández-Lozano, T. Filip, M. Sauberer +7 more
2022Journal of Controlled Release12 citations Open access
Semantic Scholar
Automated electrophilic radiosynthesis of [¹⁸F]FBPA using a modified nucleophilic GE TRACERlab FXFDG.
S. Mairinger, J. Stanek, T. Wanek, O. Langer +1 more
2015Applied Radiation and Isotopes12 citations
Semantic Scholar
Influence of ABC transporters on the excretion of ciprofloxacin assessed with PET imaging in mice.
Irene Hernández-Lozano, T. Wanek, M. Sauberer, T. Filip +6 more
2021European Journal of Pharmaceutical Sciences11 citations Open access
Semantic Scholar
Comparison of fully-automated radiosyntheses of [11C]erlotinib for preclinical and clinical use starting from in target produced [11C]CO2 or [11C]CH4
C. Philippe, S. Mairinger, V. Pichler, J. Stanek +6 more
2018EJNMMI Radiopharmacy and Chemistry11 citations Open access
Semantic Scholar
Assessing the Functional Redundancy between P-gp and BCRP in Controlling the Brain Distribution and Biliary Excretion of Dual Substrates with PET Imaging in Mice
Irene Hernández-Lozano, S. Mairinger, A. Traxl, M. Sauberer +5 more
2021Pharmaceutics10 citations Open access
Semantic Scholar
Interaction of HM30181 with P-glycoprotein at the murine blood-brain barrier assessed with positron emission tomography
Florian Bauer, T. Wanek, S. Mairinger, J. Stanek +7 more
2012European Journal of Pharmacology10 citations Open access
Semantic Scholar
Influence of P-glycoprotein on pulmonary disposition of the model substrate [11C]metoclopramide assessed by PET imaging in rats.
S. Mairinger, Irene Hernández-Lozano, T. Filip, Mathilde Löbsch +7 more
2023European Journal of Pharmaceutical Sciences9 citations Open access
Semantic Scholar
Characterization of an APP/tau rat model of Alzheimer’s disease by positron emission tomography and immunofluorescent labeling
T. Filip, S. Mairinger, J. Neddens, M. Sauberer +7 more
2021Alzheimer's Research & Therapy9 citations Open access
Semantic Scholar
[11C]Erlotinib PET cannot detect acquired erlotinib resistance in NSCLC tumor xenografts in mice.
A. Traxl, Taraneh Beikbaghban, T. Wanek, K. Kryeziu +8 more
2017Nuclear Medicine and Biology8 citations
Semantic Scholar
Brain Distribution of Dual ABCB1/ABCG2 Substrates Is Unaltered in a Beta-Amyloidosis Mouse Model
T. Wanek, V. Zoufal, M. Brackhan, M. Krohn +7 more
2020International Journal of Molecular Sciences7 citations Open access
Semantic Scholar
Positron Emission Tomography-Based Pharmacokinetic Analysis To Assess Renal Transporter-Mediated Drug-Drug Interactions of Antimicrobial Drugs
Irene Hernández-Lozano, S. Mairinger, T. Filip, Mathilde Löbsch +8 more
2023Antimicrobial Agents and Chemotherapy6 citations Open access
Semantic Scholar
Synthesis, radiolabeling, and preclinical in vivo evaluation of 68Ga-radiolabelled nanodiamonds.
T. Wanek, S. Mairinger, Marco Raabe, Md Noor A. Alam +8 more
2022Nuclear Medicine and Biology6 citations Open access
Semantic Scholar

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O. Langer×44
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O. Langer — researcher profile on SciRah
T. Wanek×43
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T. Wanek — researcher profile on SciRah
S. Mairinger×36
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S. Mairinger — researcher profile on SciRah
C. Kuntner×33
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C. Kuntner — researcher profile on SciRah

×23

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T. Filip — researcher profile on SciRah

M. Sauberer×22

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M. Sauberer — researcher profile on SciRah

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M. Müller — researcher profile on SciRah

W. Löscher×15

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J. Bankstahl×14

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J. Bankstahl — researcher profile on SciRah

M. Bankstahl×12

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M. Bankstahl — researcher profile on SciRah

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M. Bauer — researcher profile on SciRah

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R. Karch — researcher profile on SciRah