Affiong I. Oqua

Most-cited papers

1. Integration of GPCR Signaling and Sorting from Very Early Endosomes via Opposing APPL1 Mechanisms

   Silvia Sposini, F. Jean-Alphonse, M. Ayoub, Affiong I. Oqua +5 more

   2017Cell Reports92 citations Open access

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2. Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells

   Teresa Buenaventura, S. Bitsi, W. E. Laughlin, T. Burgoyne +16 more

   2019PLoS Biology78 citations Open access

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3. Divergent acute versus prolonged pharmacological GLP-1R responses in adult β cell–specific β-arrestin 2 knockout mice

   S. Bitsi, Liliane El Eid, Yusman Manchanda, Affiong I. Oqua +7 more

   2023Science Advances27 citations Open access

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4. Engineered mini-G proteins block the internalization of cognate GPCRs and disrupt downstream intracellular signaling

   Yusman Manchanda, Liliane ElEid, Affiong I. Oqua, Zenouska Ramchunder +7 more

   2024Science Signaling20 citations

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5. GLP-1R associates with VAPB and SPHKAP at ERMCSs to regulate β-cell mitochondrial remodelling and function

   Gregory Austin, Affiong I. Oqua, Liliane El Eid, Ming-Li Zhu +20 more

   2025Nature Communications14 citations Open access

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6. OSBP-mediated PI(4)P-cholesterol exchange at endoplasmic reticulum-secretory granule contact sites controls insulin secretion

   Styliani Panagiotou, Kia-Wee Tan, P. Nguyen, Andreas Müller +7 more

   2023bioRxiv9 citations Open access

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7. Molecular mapping and functional validation of GLP-1R cholesterol binding sites in pancreatic beta cells

   Affiong I. Oqua, Kin Chao, Liliane El Eid, Lisa Casteller +7 more

   2025bioRxiv7 citations Open access

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8. Human class B1 GPCR modulation by plasma membrane lipids

   Kin Chao, Linda Wong, Affiong I. Oqua, Jas Kalayan +5 more

   2025bioRxiv6 citations Open access

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9. Lipid regulation of the glucagon receptor family

   Affiong I. Oqua, Yusman Manchanda, E. McGlone, B. Jones +2 more

   2024Journal of Endocrinology5 citations Open access

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10. GLP-1R associates with VAPB and SPHKAP at ERMCSs to regulate β-cell mitochondrial remodelling and function

    Gregory Austin, Affiong I. Oqua, Liliane El Eid, Ming-Li Zhu +19 more

    2025bioRxiv3 citations Open access

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11. In vivo functional profiling and structural characterisation of the human Glp1r A316T variant

    Liliane El Eid, Kieran Deane-Alder, Roxana-Maria Rujan, Zamara Mariam +16 more

    2024bioRxiv3 citations Open access

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12. In vivo functional profiling and structural characterization of the human GLP1R A316T variant

    Liliane El Eid, Yusman Manchanda, Gregory Austin, Kieran Deane-Alder +17 more

    2026Science Advances2 citations Open access

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13. Agonist binding affinity determines palmitoylation of the glucagon-like peptide-1 receptor and its functional interaction with plasma membrane nanodomains in pancreatic beta cells

    Teresa Buenaventura, W. E. Laughlin, S. Bitsi, T. Burgoyne +13 more

    2018bioRxiv2 citations Open access

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14. Modulation of class B GPCRs by their lipid environment

    Kin Chao, Affiong I. Oqua, Alejandra Tomas, Sarah L Rouse

    2024Biophysical Journal0 citations Open access

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15. Single molecule SNAP-GLP-1R tracking data

    Teresa Buenaventura, S. Bitsi, W. E. Laughlin, T. Burgoyne +16 more

    20190 citations

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