S. Vu

Most-cited papers

The conformational wave in capsaicin activation of transient receptor potential vanilloid 1 ion channel
Fan Yang, Xian Xiao, B. Lee, S. Vu +3 more
2018Nature Communications87 citations Open access
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A non-covalent ligand reveals biased agonism of the TRPA1 ion channel
Chang Liu, Rebecca M. Reese, S. Vu, L. Rougé +20 more
2020Neuron80 citations Open access
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Structural mechanisms underlying activation of TRPV1 channels by pungent compounds in gingers
Yue Yin, Ya-Wen Dong, S. Vu, Fan Yang +3 more
2019British Journal of Pharmacology59 citations Open access
Semantic Scholar
Rational design and validation of a vanilloid-sensitive TRPV2 ion channel
Fan Yang, S. Vu, Vladimir Yarov-Yarovoy, Jie Zheng
2016Proceedings of the National Academy of Sciences of the United States of America52 citations Open access
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A distinct structural mechanism underlies TRPV1 activation by piperine
Ya-Wen Dong, Yue Yin, S. Vu, Fan Yang +3 more
2019Biochemical and Biophysical Research Communications - BBRC51 citations Open access
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Gain-of-Function Mutations in TRPM4 Activation Gate Cause Progressive Symmetric Erythrokeratodermia.
Hui-Jun Wang, Zhe Xu, B. Lee, S. Vu +8 more
2019Journal of Investigative Dermatology46 citations Open access
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Src regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epithelium.
Samuel Chung, S. Vu, S. Filosto, T. Goldkorn
2015American Journal of Respiratory Cell and Molecular Biology20 citations Open access
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A centipede toxin causes rapid desensitization of nociceptor TRPV1 ion channel
A. Zhu, Aerziguli Aierken, Zhi-Hao Yao, S. Vu +4 more
2020Toxicon19 citations Open access
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A specialized pore turret in the mammalian cation channel TRPV1 is responsible for distinct and species-specific heat activation thresholds
Guangxu Du, Yu-Hua Tian, Zhi-Hao Yao, S. Vu +4 more
2020Journal of Biological Chemistry19 citations Open access
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New capsaicin analogs as molecular rulers to define the permissive conformation of the mouse TRPV1 ligand-binding pocket
S. Vu, Vikrant Singh, H. Wulff, Vladimir Yarov-Yarovoy +1 more
2020eLife14 citations Open access
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Exploring functional roles of TRPV1 intracellular domains with unstructured peptide-insertion screening
Lin-Lin Ma, Fan Yang, S. Vu, Jie Zheng
2016Scientific Reports13 citations Open access
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Gain-of-function of TRPM4 predisposes mice to psoriasiform dermatitis
Daisuke Yamada, S. Vu, Xue-Song Wu, Zhenrui Shi +5 more
2022Frontiers in Immunology8 citations Open access
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Structural basis for agonist and heat activation of nociceptor TRPM3
Sushant Kumar, Fei Jin, Sung Jin Park, Wooyoung Choi +5 more
2025Nature Structural & Molecular Biology7 citations Open access
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Opening of capsaicin receptor TRPV1 is stabilized equally by its four subunits
Shi-Sheng Li, P. Nguyen, S. Vu, Vladimir Yarov-Yarovoy +1 more
2023Journal of Biological Chemistry6 citations Open access
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Bioactive lipid-mediated structural and functional regulation of the essential human potassium channel Kir7.1
Qingwei Niu, S. Vu, Yuan-Jian Xu, Ming-Xing Qian +8 more
2026Nature Communications2 citations Open access
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Convergent Agonist and Heat Activation of Nociceptor TRPM3
Sushant Kumar, Fei Jin, Sung Jin Park, Wooyoung Choi +5 more
2025bioRxiv2 citations Open access
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Heat- and PIP2-dependent TRPM4 activity underlies mutually exclusive human diseases
Yu-Hua Tian, Soohyeon Bae, Xuesong Wu, Kyle C. Rouen +11 more
2026Proceedings of the National Academy of Sciences of the United States of America1 citations Open access
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BPS2026 – Heat- and PIP2-dependent TRPM4 activity underlies mutually exclusive human diseases
Yuhua Tian, S. Bae, Xue-Song Wu, Kyle C. Rouen +9 more
2026Biophysical Journal0 citations
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Distinct functional open states of the polymodal nociceptor TRPV1
B. Lee, Shi-Sheng Li, S. Vu, Zhi-Hao Yao +3 more
2026Proceedings of the National Academy of Sciences of the United States of America0 citations Open access
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The preference for ammonium may be attributed to a hyperpolarized membrane potential via TWIK-1 channels.
Lanying Pan, Brendan Zhu, S. Vu, A. Stalin +3 more
2025Brain Research0 citations Open access
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Quantitative determination of vanilloid activation in TRPV1
Shi-Sheng Li, P. Nguyen, S. Vu, Vladimir Yarov-Yarovoy +1 more
2024Biophysical Journal0 citations
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TRPV1 Opening is Stabilized Equally by Its Four Subunits
Shi-Sheng Li, P. Nguyen, S. Vu, Vladimir Yarov-Yarovoy +1 more
2023bioRxiv0 citations Open access
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Distinct open states of TRPV1 induced by capsaicin and RTX
Shi-Sheng Li, S. Vu, Jie Zheng
2022Biophysical Journal0 citations Open access
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153 A specific mutation in TRPM4 predisposes mice to psoriasiform dermatitis (PsD)
D. Yamada, S. Vu, Xue-Song Wu, Zhen-Rui Shi +3 more
20210 citations Open access
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A Set of Novel Capsaicin Analogs as Molecular Ruler for Conformational Change of the TRPV1 Ligand-Binding Pocket
S. Vu, Vikrant Singh, Fan Yang, H. Wulff +1 more
20200 citations Open access
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Gain-Of-Function Mutationsin TRPM4 Activation Gate Cause Skin Disease PSEK
Hui-Jun Wang, Zhe Xu, Bo Hyun Lee, S. Vu +8 more
2019Biophysical Journal0 citations Open access
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Short- and Long-Distance Allosteric Coupling in Capsaicin-Induced TRPV1 Activation
S. Vu, Bo Hyun Lee, Xian Xiao, Fan Yang +1 more
2019Biophysical Journal0 citations Open access
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Title The conformational wave in capsaicin activation of transient receptor potential vanilloid 1 ion channel Permalink
Fan Yang, Xian Xiao, B. Lee, S. Vu +3 more
20180 citations
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Activation of TRPV1 by Capsaicin Analogs with a Shorter or Longer Neck
S. Vu, Vikrant Singh, Fan Yang, H. Wulff +1 more
20180 citations Open access
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Kinetic Analysis of Vanilloid-Induced Activation in TRPV1 Channel
S. Vu, B. Lee, Jie Zheng
20170 citations Open access
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