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Aijazuddin Syed · SciRah

Researcher profile · Semantic Scholar

Aijazuddin Syed

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Aijazuddin Syed — researcher profile on SciRah

h-index: 18
Works: 59
Citations: 9,485

Most-cited papers

Mutational Landscape of Metastatic Cancer Revealed from Prospective Clinical Sequencing of 10,000 Patients
A. Zehir, R. Benayed, Ronak H. Shah, Aijazuddin Syed +96 more
2017Nature Medicine3,034 citations Open access
Semantic Scholar
Memorial Sloan Kettering-Integrated Mutation Profiling of Actionable Cancer Targets (MSK-IMPACT): A Hybridization Capture-Based Next-Generation Sequencing Clinical Assay for Solid Tumor Molecular Oncology.
D. Cheng, Talia Mitchell, A. Zehir, Ronak H. Shah +23 more
2015Journal of Molecular Diagnostics2,006 citations Open access
Semantic Scholar
Clinical sequencing defines the genomic landscape of metastatic colorectal cancer
R. Yaeger, W. Chatila, Marla D Lipsyc, J. Hechtman +25 more
2018Cancer Cell804 citations Open access
Semantic Scholar
Therapy-related clonal hematopoiesis in patients with non-hematologic cancers is common and impacts clinical outcome
Catherine C. Coombs, A. Zehir, S. Devlin, A. Kishtagari +11 more
2017Cell Stem Cell737 citations Open access
Semantic Scholar
Cancer therapy shapes the fitness landscape of clonal hematopoiesis
K. Bolton, R. Ptashkin, Teng Gao, L. Braunstein +60 more
2020Nature Genetics640 citations Open access
Semantic Scholar
Prospective Genomic Profiling of Prostate Cancer Across Disease States Reveals Germline and Somatic Alterations That May Affect Clinical Decision Making
W. Abida, J. Armenia, A. Gopalan, R. Brennan +37 more
2017JCO Precision Oncology490 citations Open access
Semantic Scholar
Mutation Detection in Patients With Advanced Cancer by Universal Sequencing of Cancer-Related Genes in Tumor and Normal DNA vs Guideline-Based Germline Testing
D. Mandelker, Liying Zhang, Y. Kemel, Z. Stadler +47 more
2017Journal of the American Medical Association (JAMA)463 citations Open access
Semantic Scholar
Quantifying the Expanding Landscape of Clinical Actionability for Patients with Cancer
S. Suehnholz, Moriah H. Nissan, Hong-Xin Zhang, R. Kundra +22 more
2023Cancer Discovery302 citations Open access
Semantic Scholar
Genetic Determinants of Cisplatin Resistance in Patients With Advanced Germ Cell Tumors.
A. Bagrodia, Byron H. Lee, William Lee, E. Cha +26 more
2016Journal of Clinical Oncology168 citations Open access
Semantic Scholar
OncoTree: A Cancer Classification System for Precision Oncology.
R. Kundra, Hong-Xin Zhang, R. Sheridan, S. Sirintrapun +62 more
2021JCO Clinical Cancer Informatics143 citations Open access
Semantic Scholar
Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing
D. Cheng, Meera Prasad, Y. Chekaluk, R. Benayed +14 more
2017BMC Medical Genomics142 citations Open access
Semantic Scholar
Development of Genome-Derived Tumor Type Prediction to Inform Clinical Cancer Care.
A. Penson, Niedzica Camacho, Youyun Zheng, A. Varghese +20 more
2019JAMA Oncology107 citations Open access
Semantic Scholar
Widespread selection for oncogenic mutant allele imbalance in cancer
C. Bielski, M. Donoghue, M. Gadiya, Aphrothiti J. Hanrahan +16 more
2018Cancer Cell101 citations Open access
Semantic Scholar
The context-specific role of germline pathogenicity in tumorigenesis
P. Srinivasan, C. Bandlamudi, P. Jonsson, Y. Kemel +34 more
2021Nature Genetics92 citations Open access
Semantic Scholar
Corrigendum: Analysis of self-antigen specificity of islet-infiltrating T cells from human donors with type 1 diabetes
A. Zehir, R. Benayed, Ronak H. Shah, Aijazuddin Syed +96 more
2017Nature Medicine56 citations Open access
Semantic Scholar
Diagnostic yield and clinical relevance of expanded genetic testing for cancer patients
O. Ceyhan-Birsoy, G. Jayakumaran, Y. Kemel, M. Misyura +21 more
2022Genome Medicine36 citations Open access
Semantic Scholar
Detection of mutations in myeloid malignancies through paired-sample analysis of microdroplet-PCR deep sequencing data.
D. Cheng, Janice Cheng, Talia Mitchell, Aijazuddin Syed +8 more
2014Journal of Molecular Diagnostics28 citations Open access
Semantic Scholar
Oncologic therapy shapes the fitness landscape of clonal hematopoiesis
K. Bolton, R. Ptashkin, Teng Gao, L. Braunstein +60 more
2019bioRxiv25 citations Open access
Semantic Scholar
Comprehensive detection of germline variants by MSK-IMPACT, a clinical diagnostic platform for solid tumor molecular oncology and concurrent cancer predisposition testing
D. Cheng, Meera Prasad, Y. Chekaluk, R. Benayed +14 more
2017BMC Medical Genomics18 citations Open access
Semantic Scholar
DeepHeme, a high-performance, generalizable deep ensemble for bone marrow morphometry and hematologic diagnosis.
Sheng-Huan Sun, Zhang-Han Yin, Jacob G. Van Cleave, Lin-Lin Wang +27 more
2025Science Translational Medicine15 citations
Semantic Scholar
Deep-Learning Model for Tumor-Type Prediction Using Targeted Clinical Genomic Sequencing Data
Madison Darmofal, Shalabh Suman, Gurnit Atwal, Michael Toomey +9 more
2024Cancer Discovery14 citations Open access
Semantic Scholar
Deep Learning Model for Tumor Type Prediction using Targeted Clinical Genomic Sequencing Data
Madison Darmofal, Shalabh Suman, Gurnit Atwal, Jie-Fu Chen +9 more
2023medRxiv13 citations Open access
Semantic Scholar
Translational Bioinformatics and Clinical Research (Biomedical) Informatics.
S. Sirintrapun, A. Zehir, Aijazuddin Syed, Jian-Jiong Gao +2 more
2016Clinics in Laboratory Medicine12 citations
Semantic Scholar
Abstract 6585: OncoKB, MSK’s precision oncology knowledge base
S. Suehnholz, Moriah H. Nissan, Hong-Xin Zhang, R. Kundra +16 more
2023Cancer Research9 citations
Semantic Scholar
Enhanced specificity of high sensitivity somatic variant profiling in cell-free DNA via paired normal sequencing: design, validation, and clinical experience of the MSK-ACCESS liquid biopsy assay
A. Brannon, G. Jayakumaran, M. Diosdado, J. Patel +65 more
2020bioRxiv9 citations Open access
Semantic Scholar
Java GUI for InterProScan (JIPS): A tool to help process multiple InterProScans and perform ortholog analysis
Aijazuddin Syed, C. Upton
2006BMC Bioinformatics9 citations Open access
Semantic Scholar
Enhanced specificity of clinical high-sensitivity tumor mutation profiling in cell-free DNA via paired normal sequencing using MSK-ACCESS
A. Rose Brannon, G. Jayakumaran, Monica Diosdado, J. Patel +65 more
2021Nature Communications8 citations Open access
Semantic Scholar
Cancer type-specific variation in patterns of driver alterations across 50,000 tumors
C. Bandlamudi, D. Muldoon, I. de Bruijn, Mingxuan Zhang +85 more
2026Cancer Cell7 citations Open access
Semantic Scholar
Translational Bioinformatics and Clinical Research (Biomedical) Informatics.
S. Sirintrapun, A. Zehir, Aijazuddin Syed, Jian-Jiong Gao +2 more
2015Surgical Pathology Clinics4 citations
Semantic Scholar
Abstract 99: Evolution of OncoKB, a precision oncology knowledgebase
S. Suehnholz, R. Kundra, Hong-Xin Zhang, Shaleigh A. Smith +18 more
2021Clinical research3 citations
Semantic Scholar
Clinical Bioinformatician Body of Knowledge - Clinical Laboratory Regulation and Data Security Core: A Report of the Association for Molecular Pathology.
Ryan J. Schmidt, Larissa V. Furtado, Amber M. Fussell, Danielle Jordan +6 more
2025Journal of Molecular Diagnostics2 citations Open access
Semantic Scholar
DNA Mutational and Copy Number Variation Profiling of Primary Craniofacial Osteosarcomas by Next-Generation Sequencing
G. Zhu, Chuanyong Lu, I. Petrović, K. Nafa +10 more
2024Head and Neck Pathology2 citations Open access
Semantic Scholar
Cancer type-specific variation in patterns of driver alterations across 50,000 tumors.
C. Bandlamudi, D. Muldoon, I. de Bruijn, Mingxuan Zhang +85 more
2026Cancer Cell1 citations Open access
Semantic Scholar
Interpretable multiple instance learning for hematologic diagnosis from peripheral blood smears
S. Singi, Sheng-Huan Sun, Zhang-Han Yin, Riya Gupta +37 more
2026Communications Medicine1 citations Open access
Semantic Scholar
Abstract 5440: Deep-learning model for tumor type classification enables enhanced clinical decision support in cancer diagnosis
Madison Darmofal, Shalabh Suman, Gurnit Atwal, Jie-Fu Chen +6 more
2023Cancer Research1 citations
Semantic Scholar
Variability in genomic alterations between right- and left-sided microsatellite stable (MSS) metastatic colorectal cancer and impact on survival.
R. Yaeger, W. Chatila, Marla D Lipsyc, F. Sánchez-Vega +16 more
20171 citations
Semantic Scholar
Organizing and updating whole genome BLAST searches with ReHAB.
D. J. Esteban, Aijazuddin Syed, C. Upton
2007Methods in molecular biology1 citations
Semantic Scholar
Abstract 2498: OncoKB™, MSK’s precision oncology knowledge base: 2025 updates
S. Suehnholz, R. Kundra, Moriah H. Nissan, Calvin Lu +28 more
2026Cancer Research0 citations
Semantic Scholar
533 AI-Based Bone Marrow Aspirate Differentials with Real-World Distribution Shift Calibration
Zhang-Han Yin, Sheng-Huan Sun, Brenda Fried, Cesar Colorado-Jimenez +15 more
2026Laboratory Investigation0 citations
Semantic Scholar
1363 Design and Usability Testing of a Web-Based Application for AI-Assisted Bone Marrow Aspirate Differentials
Jacob G. Van Cleave, Brenda Fried, Cesar Colorado-Jimenez, Zhang-Han Yin +10 more
2026Laboratory Investigation0 citations
Semantic Scholar
An AI-powered self-driving microscope for low-cost acute leukemia detection
Ethan S. Yan, Sheng-Huan Sun, Zhang-Han Yin, A. Kamali +25 more
2026Nature Communications0 citations Open access
Semantic Scholar
Interpretable Multiple Instance Learning for Hematologic Diagnosis from Peripheral Blood Smears
S. Singi, Sheng-Huan Sun, Zhang-Han Yin, Riya Gupta +37 more
2025Research Square0 citations Open access
Semantic Scholar
Abstract 1066: OncoKBTM, MSK’s precision oncology knowledge base: 2024 updates
Moriah H. Nissan, S. Suehnholz, Hong-Xin Zhang, R. Kundra +22 more
2025Cancer Research0 citations
Semantic Scholar
Tracking the FDA precision oncology drug approval landscape in OncoKB.
S. Suehnholz, R. Kundra, Hong-Xin Zhang, Moriah H. Nissan +15 more
2024Journal of Clinical Oncology0 citations Open access
Semantic Scholar
Abstract 3544: OncoKB™, MSK’s precision oncology knowledge base: 2023 updates
S. Suehnholz, Moriah H. Nissan, Hong-Xin Zhang, R. Kundra +15 more
2024Cancer Research0 citations
Semantic Scholar
Quantifying the growth of clinical actionability in precision oncology using OncoKB.
S. Suehnholz, R. Kundra, Subhiksha Nandakumar, Moriah H. Nissan +16 more
2023Journal of Clinical Oncology0 citations
Semantic Scholar
Abstract 5214: Expanding the spectrum of germline-driven cancers by leveraging population-scale targeted tumor and normal sequencing
Miika Mehine, Rebecca Caeser, Y. Kemel, Daniel M Muldoon +15 more
2023Cancer Research0 citations
Semantic Scholar
Ancestry-adjusted genomic analysis to identify known and novel associations with single and multiple cancer phenotypes.
V. Joseph, Vignesh Ravichandran, I. Ostrovnaya, Ying L. Liu +14 more
2023Journal of Clinical Oncology0 citations
Semantic Scholar
Abstract 1189: OncoKB, MSK’s precision oncology knowledge base
S. Suehnholz, Moriah H. Nissan, Hong-Xin Zhang, R. Kundra +14 more
2022Cancer Research0 citations
Semantic Scholar
Abstract PR08: Validation and clinical implementation of MSK-ACCESS, an ultra-deep sequencing assay for noninvasive somatic mutation profiling
A. Brannon, G. Jayakumaran, M. Diosdado, Yu Hu +19 more
2020Oral Presentations - Proffered Abstracts0 citations
Semantic Scholar

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