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P. Canonico · SciRah

Researcher profile · Semantic Scholar

P. Canonico

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P. Canonico — researcher profile on SciRah

h-index: 47
Works: 244
Citations: 7,274

Most-cited papers

Click chemistry reactions in medicinal chemistry: Applications of the 1,3‐dipolar cycloaddition between azides and alkynes
G. Tron, T. Pirali, R. Billington, P. Canonico +2 more
2008Medicinal research reviews (Print)907 citations
Semantic Scholar
Amyloid beta deregulates astroglial mGluR5‐mediated calcium signaling via calcineurin and Nf‐kB
D. Lim, A. Iyer, V. Ronco, A. Grolla +3 more
2013Glia161 citations Open access
Semantic Scholar
DPYD IVS14+1G>A and 2846A>T genotyping for the prediction of severe fluoropyrimidine-related toxicity: a meta-analysis.
S. Terrazzino, S. Cargnin, M. Del Re, R. Danesi +2 more
2013Pharmacogenomics (London)150 citations
Semantic Scholar
Characterization of NAD Uptake in Mammalian Cells*
R. Billington, C. Travelli, E. Ercolano, Ubaldina Galli +5 more
2008Journal of Biological Chemistry96 citations Open access
Semantic Scholar
Aβ leads to Ca²⁺ signaling alterations and transcriptional changes in glial cells.
A. Grolla, G. Fakhfouri, G. Balzaretti, Elena Marcello +5 more
2013Neurobiology of Aging93 citations
Semantic Scholar
A novel potent nicotinamide phosphoribosyltransferase inhibitor synthesized via click chemistry.
Giampiero Colombano, C. Travelli, Ubaldina Galli, A. Caldarelli +6 more
2010Journal of Medicinal Chemistry89 citations
Semantic Scholar
Differential deregulation of astrocytic calcium signalling by amyloid-β, TNFα, IL-1β and LPS.
V. Ronco, A. Grolla, T. Glasnov, P. Canonico +3 more
2014Cell Calcium80 citations
Semantic Scholar
Upregulation of mGlu2 Receptors via NF-κB p65 Acetylation Is Involved in the Proneurogenic and Antidepressant Effects of Acetyl-L-Carnitine
B. Cuccurazzu, Valeria Bortolotto, M. Valente, F. Ubezio +3 more
2013Neuropsychopharmacology78 citations Open access
Semantic Scholar
The effect of CYP3A5 6986A>G and ABCB1 3435C>T on tacrolimus dose-adjusted trough levels and acute rejection rates in renal transplant patients: a systematic review and meta-analysis.
S. Terrazzino, M. Quaglia, P. Stratta, P. Canonico +1 more
2012Pharmacogenetics & Genomics77 citations
Semantic Scholar
Astrocyte-Derived Paracrine Signals: Relevance for Neurogenic Niche Regulation and Blood–Brain Barrier Integrity
S. Spampinato, Valeria Bortolotto, P. Canonico, M. Sortino +1 more
2019Frontiers in Pharmacology72 citations Open access
Semantic Scholar
l-Acetylcarnitine: A Mechanistically Distinctive and Potentially Rapid-Acting Antidepressant Drug
S. Chiechio, P. Canonico, M. Grilli
2017International Journal of Molecular Sciences68 citations Open access
Semantic Scholar
NF-κB Mediated Regulation of Adult Hippocampal Neurogenesis: Relevance to Mood Disorders and Antidepressant Activity
Valeria Bortolotto, B. Cuccurazzu, P. Canonico, M. Grilli
2014BioMed Research International64 citations Open access
Semantic Scholar
Identification of a sirtuin 3 inhibitor that displays selectivity over sirtuin 1 and 2.
Ubaldina Galli, Ornella Mesenzani, C. Coppo, G. Sorba +3 more
2012European journal of medicinal chemistry63 citations Open access
Semantic Scholar
Price and reimbursement of advanced therapeutic medicinal products in Europe: are assessment and appraisal diverging from expert recommendations?
V. Ronco, M. Dilecce, E. Lanati, P. Canonico +1 more
2021Journal of Pharmaceutical Policy and Practice62 citations Open access
Semantic Scholar
An opposite-direction modulation of the COMT Val158Met polymorphism on the clinical response to intrathecal morphine and triptans.
S. Cargnin, F. Magnani, M. Viana, C. Tassorelli +8 more
2013Journal of Pain56 citations Open access
Semantic Scholar
Biosimilar Drugs
A. Genazzani, G. Biggio, A. Caputi, M. del Tacca +3 more
2012BioDrugs53 citations
Semantic Scholar
Common variants of eNOS and XRCC1 genes may predict acute skin toxicity in breast cancer patients receiving radiotherapy after breast conserving surgery.
S. Terrazzino, Pierdaniele La Mattina, L. Masini, Tina Caltavuturo +4 more
2012Radiotherapy and Oncology52 citations
Semantic Scholar
α2δ Ligands Act as Positive Modulators of Adult Hippocampal Neurogenesis and Prevent Depression-Like Behavior Induced by Chronic Restraint Stress
M. Valente, Valeria Bortolotto, B. Cuccurazzu, F. Ubezio +4 more
2012Molecular Pharmacology51 citations
Semantic Scholar
Identification of Novel Triazole-Based Nicotinamide Phosphoribosyltransferase (NAMPT) Inhibitors Endowed with Antiproliferative and Antiinflammatory Activity.
C. Travelli, Silvio Aprile, R. Rahimian, A. Grolla +22 more
2017Journal of Medicinal Chemistry50 citations Open access
Semantic Scholar
Common variants of GSTP1, GSTA1, and TGFβ1 are associated with the risk of radiation-induced fibrosis in breast cancer patients.
S. Terrazzino, Pierdaniele La Mattina, G. Gambaro, L. Masini +4 more
2012International Journal of Radiation Oncology, Biology, Physics50 citations
Semantic Scholar
Ring finger protein 10 is a novel synaptonuclear messenger encoding activation of NMDA receptors in hippocampus
M. Dinamarca, Francesca Guzzetti, Anna Karpova, D. Lim +15 more
2016eLife49 citations Open access
Semantic Scholar
Replacement of the double bond of antitubulin chalcones with triazoles and tetrazoles: Synthesis and biological evaluation.
Ornella Mesenzani, A. Massarotti, Mariateresa Giustiniano, T. Pirali +7 more
2011Bioorganic & Medicinal Chemistry Letters49 citations
Semantic Scholar
Searching for new animal models of Alzheimer's disease.
R. Epis, F. Gardoni, Elena Marcello, A. Genazzani +2 more
2010European Journal of Pharmacology48 citations
Semantic Scholar
Alzheimer's disease: brain expression of a metabolic disorder?
S. Merlo, S. Spampinato, P. Canonico, A. Copani +1 more
2010Trends in endocrinology and metabolism47 citations
Semantic Scholar
Reciprocal Potentiation of the Antitumoral Activities of FK866, an Inhibitor of Nicotinamide Phosphoribosyltransferase, and Etoposide or Cisplatin in Neuroblastoma Cells
C. Travelli, V. Drago, E. Maldi, N. Kaludercic +6 more
2011Journal of Pharmacology and Experimental Therapeutics46 citations
Semantic Scholar
Solution-phase parallel synthesis and biological evaluation of combretatriazoles.
Laura Cafici, T. Pirali, F. Condorelli, E. Del Grosso +5 more
2008Journal of combinatorial chemistry44 citations
Semantic Scholar
Primary Biliary Cholangitis: advances in management and treatment of the disease.
P. Invernizzi, A. Floreani, M. Carbone, M. Marzioni +11 more
2017Digestive and Liver Disease41 citations Open access
Semantic Scholar
The serotonin transporter gene polymorphism STin2 VNTR confers an increased risk of inconsistent response to triptans in migraine patients.
S. Terrazzino, M. Viana, E. Floriddia, F. Monaco +7 more
2010European Journal of Pharmacology41 citations
Semantic Scholar
Quantitative Analysis of Circulating Cell‐Free DNA for Correlation with Lung Cancer Survival: A Systematic Review and Meta‐Analysis
S. Cargnin, P. Canonico, A. Genazzani, S. Terrazzino
2017Journal of Thoracic Oncology39 citations Open access
Semantic Scholar
Genetic determinants of chronic oxaliplatin‐induced peripheral neurotoxicity: a genome‐wide study replication and meta‐analysis
S. Terrazzino, A. Argyriou, S. Cargnin, Anna G. Antonacopoulou +13 more
2015Journal of the peripheral nervous system37 citations
Semantic Scholar
Linagliptin: A thorough Characterization beyond Its Clinical Efficacy
M. Sortino, T. Sinagra, P. Canonico
2013Frontiers in Endocrinology37 citations Open access
Semantic Scholar
Synthesis, biological evaluation, and molecular docking of Ugi products containing a zinc-chelating moiety as novel inhibitors of histone deacetylases.
A. Grolla, V. Podestá, M. G. Chini, S. Di Micco +7 more
2009Journal of Medicinal Chemistry37 citations Open access
Semantic Scholar
Pharmacological rationale for tapentadol therapy: a review of new evidence
P. Romualdi, M. Grilli, P. Canonico, M. Collino +1 more
2019Journal of Pain Research34 citations Open access
Semantic Scholar
Unexplained Somatic Symptoms during Major Depression: Prevalence and Clinical Impact in a National Sample of Italian Psychiatric Outpatients
G. Perugi, P. Canonico, P. Carbonato, C. Mencacci +7 more
2011Psychopathology34 citations Open access
Semantic Scholar
Modulatory effect of acetyl-L-carnitine on amyloid precursor protein metabolism in hippocampal neurons.
R. Epis, Elena Marcello, F. Gardoni, Annalisa Longhi +5 more
2008European Journal of Pharmacology34 citations
Semantic Scholar
Salmeterol, a β2 Adrenergic Agonist, Promotes Adult Hippocampal Neurogenesis in a Region-Specific Manner
Valeria Bortolotto, Heather Bondi, B. Cuccurazzu, M. Rinaldi +2 more
2019Frontiers in Pharmacology33 citations Open access
Semantic Scholar
Diagnostic accuracy of NUDT15 gene variants for thiopurine‐induced leukopenia: a systematic review and meta‐analysis
S. Cargnin, A. Genazzani, P. Canonico, S. Terrazzino
2018Pharmacological Research33 citations
Semantic Scholar
Complex and regional-specific changes in the morphological complexity of GFAP+ astrocytes in middle-aged mice.
Heather Bondi, Valeria Bortolotto, P. Canonico, M. Grilli
2020Neurobiology of Aging31 citations Open access
Semantic Scholar
Cell autonomous and noncell‐autonomous role of NF‐κB p50 in astrocyte‐mediated fate specification of adult neural progenitor cells
Suzana Cvijetic, Valeria Bortolotto, M. Manfredi, E. Ranzato +4 more
2017Glia31 citations
Semantic Scholar
Tapentadol: an overview of the safety profile
E. Polati, P. Canonico, V. Schweiger, M. Collino
2019Journal of Pain Research30 citations Open access
Semantic Scholar
Gene expression, proteome and calcium signaling alterations in immortalized hippocampal astrocytes from an Alzheimer’s disease mouse model
F. Rocchio, L. Tapella, M. Manfredi, M. Chisari +9 more
2019Cell Death and Disease30 citations Open access
Semantic Scholar
Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents.
Ubaldina Galli, C. Travelli, Silvio Aprile, E. Arrigoni +7 more
2015Journal of Medicinal Chemistry30 citations
Semantic Scholar
A Concise Synthesis of Pyrazole Analogues of Combretastatin A1 as Potent Anti‐Tubulin Agents
R. Zaninetti, Salvatore V. Cortese, Silvio Aprile, A. Massarotti +5 more
2013ChemMedChem30 citations
Semantic Scholar
Activation of TRPV4 channels reduces migration of immortalized neuroendocrine cells
R. Zaninetti, Alessandra Fornarelli, M. Ciarletta, D. Lim +8 more
2011Journal of Neurochemistry30 citations
Semantic Scholar
Comparative analysis of CAR T-cell therapy access for DLBCL patients: associated challenges and solutions in the four largest EU countries
M. Canales Albendea, P. Canonico, G. Cartron, B. Deiters +6 more
2023Frontiers in Medicine29 citations Open access
Semantic Scholar
Enhanced expression of ERalpha in astrocytes modifies the response of cortical neurons to beta-amyloid toxicity.
V. Carbonaro, F. Caraci, M. L. Giuffrida, S. Merlo +4 more
2009Neurobiology of Disease28 citations Open access
Semantic Scholar
Pyrtriazoles, a Novel Class of Store-Operated Calcium Entry Modulators: Discovery, Biological Profiling, and in Vivo Proof-of-Concept Efficacy in Acute Pancreatitis.
B. Riva, Alessia Griglio, Marta Serafini, Celia Cordero-Sánchez +14 more
2018Journal of Medicinal Chemistry26 citations Open access
Semantic Scholar
Distinct effects of pramipexole on the proliferation of adult mouse sub-ventricular zone-derived cells and the appearance of a neuronal phenotype.
S. Merlo, P. Canonico, M. Sortino
2011Neuropharmacology26 citations
Semantic Scholar
TGF‐β2 and TGF‐β3 from cultured β‐amyloid‐treated or 3xTg‐AD‐derived astrocytes may mediate astrocyte–neuron communication
L. Tapella, M. Cerruti, I. Biocotino, A. Stevano +5 more
2018European Journal of Neuroscience25 citations
Semantic Scholar
Human recombinant follicle stimulating hormone (rFSH) compared to urinary human menopausal gonadotropin (HMG) for ovarian stimulation in assisted reproduction: a literature review and cost evaluation
P. L. Levi Setti, C. Alviggi, G. Colombo, C. Pisanelli +4 more
2014Journal of Endocrinological Investigation24 citations Open access
Semantic Scholar

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G. Sorba×10
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S. Terrazzino×10
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Ubaldina Galli×7

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Ubaldina Galli — researcher profile on SciRah

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S. Cargnin — researcher profile on SciRah