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C. Nerlov · SciRah

Researcher profile · Semantic Scholar

C. Nerlov

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C. Nerlov — researcher profile on SciRah

h-index: 54
Works: 183
Citations: 13K

Most-cited papers

Chronic interleukin-1 drives haematopoietic stem cells towards precocious myeloid differentiation at the expense of self-renewal
E. Pietras, Cristina Mirantes-Barbeito, Sarah L. Fong, Dirk Loeffler +11 more
2016Nature Cell Biology644 citations Open access
Semantic Scholar
Myelodysplastic syndromes are propagated by rare and distinct human cancer stem cells in vivo.
P. Woll, Una Kjällquist, Onima Chowdhury, H. Doolittle +44 more
2014Cancer Cell333 citations Open access
Semantic Scholar
Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells
J. Carrelha, Yiran Meng, Laura M. J. Kettyle, T. Luis +12 more
2018Nature324 citations Open access
Semantic Scholar
Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells
A. Grover, A. Sanjuan-Pla, S. Thongjuea, J. Carrelha +8 more
2016Nature Communications298 citations Open access
Semantic Scholar
Remodeling of Bone Marrow Hematopoietic Stem Cell Niches Promotes Myeloid Cell Expansion during Premature or Physiological Aging
Ya-Hsuan Ho, R. del Toro, José Rivera-Torres, Justyna Rak +16 more
2019Cell Stem Cell282 citations Open access
Semantic Scholar
Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia
F. Grebien, M. Vedadi, M. Getlik, R. Giambruno +27 more
2015Nature Chemical Biology261 citations Open access
Semantic Scholar
Distinct myeloid progenitor differentiation pathways identified through single cell RNA sequencing
Roy Drissen, Natalija Buza-Vidas, P. Woll, S. Thongjuea +10 more
2016Nature Immunology215 citations Open access
Semantic Scholar
Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios
Philipp S. Hoppe, Michael Schwarzfischer, Dirk Loeffler, Konstantinos D. Kokkaliaris +19 more
2016Nature201 citations Open access
Semantic Scholar
Lineage-biased hematopoietic stem cells are regulated by distinct niches
Sandra Pinho, T. Marchand, E. Yang, Qiao-Zhi Wei +2 more
2018Developmental Cell187 citations Open access
Semantic Scholar
Disease evolution and outcomes in familial AML with germline CEBPA mutations.
K. Tawana, Jun Wang, Aline Renneville, C. Bödör +37 more
2015Blood187 citations Open access
Semantic Scholar
Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate
A. Grover, E. Mancini, Susan Moore, A. Mead +5 more
2014Journal of Experimental Medicine143 citations Open access
Semantic Scholar
Micro-environmental sensing by bone marrow stroma identifies IL-6 and TGFβ1 as regulators of hematopoietic ageing
S. Valletta, Alexander Thomas, Yiran Meng, Xi-Ying Ren +4 more
2020Nature Communications111 citations Open access
Semantic Scholar
Haematopoiesis in the era of advanced single-cell technologies
S. Jacobsen, C. Nerlov
2019Nature Cell Biology107 citations
Semantic Scholar
Identification of two distinct pathways of human myelopoiesis
Roy Drissen, S. Thongjuea, K. Theilgaard-Mönch, C. Nerlov
2019Science immunology89 citations Open access
Semantic Scholar
A dynamic niche provides Kit ligand in a stage-specific manner to the earliest thymocyte progenitors
Mario Buono, R. Facchini, Sahoko Matsuoka, S. Thongjuea +7 more
2016Nature Cell Biology72 citations Open access
Semantic Scholar
Inflammatory signals directly instruct PU.1 in HSCs via TNF.
Martin Etzrodt, Nouraiz Ahmed, Philipp S. Hoppe, Dirk Loeffler +7 more
2019Blood65 citations Open access
Semantic Scholar
A transit-amplifying population underpins the efficient regenerative capacity of the testis
C. Carrieri, S. Comazzetto, A. Grover, Marcos Morgan +3 more
2017Journal of Experimental Medicine57 citations Open access
Semantic Scholar
Initial seeding of embryonic thymus by immune-restricted lympho-myeloid progenitors
T. Luis, Sidinh Luc, Takuo Mizukami, Hanane Boukarabila +20 more
2016Nature Immunology57 citations Open access
Semantic Scholar
Kit ligand has a critical role in mouse yolk sac and aorta–gonad–mesonephros hematopoiesis
Emanuele Azzoni, Vincent Frontera, K. McGrath, J. Harman +5 more
2018EMBO Reports54 citations Open access
Semantic Scholar
Niche-mediated depletion of the normal hematopoietic stem cell reservoir by Flt3-ITD–induced myeloproliferation
A. Mead, Wen Hao Neo, Nikolaos Barkas, Sahoko Matsuoka +18 more
2017Journal of Experimental Medicine50 citations Open access
Semantic Scholar
Ontogenic changes in hematopoietic hierarchy determine pediatric specificity and disease phenotype in fusion oncogene-driven myeloid leukemia.
Cécile K. Lopez, Esteve Noguera, V. Stavropoulou, E. Robert +32 more
2019Cancer Discovery49 citations Open access
Semantic Scholar
CD34 and EPCR coordinately enrich functional murine hematopoietic stem cells under normal and inflammatory conditions
Jennifer L. Rabe, Giovanny Hernandez, James S. Chavez, Taylor S. Mills +2 more
2019Experimental Hematology45 citations Open access
Semantic Scholar
Multiple membrane extrusion sites drive megakaryocyte migration into bone marrow blood vessels
Edward Brown, L. Carlin, C. Nerlov, Cristina Lo Celso +1 more
2018Life Science Alliance44 citations Open access
Semantic Scholar
Epigenetic programming defines haematopoietic stem cell fate restriction
Yiran Meng, J. Carrelha, Roy Drissen, Xi-Ying Ren +6 more
2023Nature Cell Biology36 citations Open access
Semantic Scholar
CEBPA-mutated leukemia is sensitive to genetic and pharmacological targeting of the MLL1 complex
L. Schmidt, Elizabeth Heyes, Lisa Scheiblecker, T. Eder +6 more
2019Leukemia36 citations Open access
Semantic Scholar
Slow integrin-dependent migration organizes networks of tissue-resident mast cells
Lukas Kaltenbach, Paloma Martzloff, Sarah K. Bambach, Nadim Aizarani +17 more
2022bioRxiv34 citations Open access
Semantic Scholar
Single cell analysis of bone marrow derived CD34+ cells from children with sickle cell disease and thalassemia.
P. Hua, N. Roy, J. de la Fuente, Guan-Lin Wang +10 more
2019Blood34 citations Open access
Semantic Scholar
Myeloid lineage enhancers drive oncogene synergy in CEBPA/CSF3R mutant acute myeloid leukemia
Theodore P. Braun, M. Okhovat, Cody Coblentz, S. Carratt +24 more
2019Nature Communications34 citations Open access
Semantic Scholar
C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor
C. Di Genua, S. Valletta, Mario Buono, B. Stoilova +13 more
2020Cancer Cell27 citations Open access
Semantic Scholar
Wnt/β-Catenin Signaling Induces Integrin α4β1 in T Cells and Promotes a Progressive Neuroinflammatory Disease in Mice
D. Sorcini, S. Bruscoli, Tiziana Frammartino, M. Cimino +18 more
2017Journal of Immunology22 citations Open access
Semantic Scholar
Canonical Notch signaling is dispensable for adult steady-state and stress myelo-erythropoiesis.
S. Duarte, P. Woll, Natalija Buza-Vidas, D. Chin +18 more
2018Blood21 citations Open access
Semantic Scholar
Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.
M. Cirilli, O. Bereshchenko, O. Ermakova, C. Nerlov
2017Biochimica et Biophysica Acta - General Subjects20 citations
Semantic Scholar
Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner
T. Luis, Nikolaos Barkas, J. Carrelha, Alice Giustacchini +17 more
2023Nature Communications19 citations Open access
Semantic Scholar
Liver haploinsufficiency of RuvBL1 causes hepatic insulin resistance and enhances hepatocellular carcinoma progression
T. Mello, M. Materozzi, F. Zanieri, I. Simeone +10 more
2019International Journal of Cancer17 citations Open access
Semantic Scholar
Direct role of FLT3 in regulation of early lymphoid progenitors
Alya Zriwil, Charlotta Böiers, T. Kristiansen, Lilian Wittmann +4 more
2018British Journal of Haematology17 citations Open access
Semantic Scholar
Human adult HSCs can be discriminated from lineage-committed HPCs by the expression of endomucin.
K. Reckzeh, Hüsün S. Kizilkaya, A. S. Helbo, M. Alrich +10 more
2018Blood Advances16 citations Open access
Semantic Scholar
Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation
C. Di Genua, Ruggiero Norfo, A. Rodriguez-Meira, W. Wen +12 more
2019Haematologica15 citations Open access
Semantic Scholar
Bi-directional signaling by membrane-bound KitL induces proliferation and coordinates thymic endothelial cell and thymocyte expansion
Mario Buono, M. Thézénas, A. Ceroni, R. Fischer +1 more
2018Nature Communications15 citations Open access
Semantic Scholar
Endothelial cell death after ionizing radiation does not impair vascular structure in mouse tumor models
Jakob Kaeppler, Jianzhou Chen, Mario Buono, J. Vermeer +14 more
2022EMBO Reports12 citations Open access
Semantic Scholar
Dependence on Myb expression is attenuated in myeloid leukaemia with N-terminal CEBPA mutations
G. Volpe, P. Cauchy, D. Walton, C. Ward +9 more
2019Life Science Alliance10 citations Open access
Semantic Scholar
Selective advantage of mutant stem cells in clonal hematopoiesis occurs by attenuating the deleterious effects of inflammation and aging
N. A. Jakobsen, Sven Turkalj, Andy G. X. Zeng, B. Stoilova +25 more
2023bioRxiv9 citations Open access
Semantic Scholar
DNMT1 deficiency impacts on plasmacytoid dendritic cells in homeostasis and autoimmune disease
M. Czéh, Sina Staeble, Stephen Krämer, Lena Tepe +14 more
2021Journal of Immunology9 citations Open access
Semantic Scholar
Panhematopoietic RNA barcoding enables kinetic measurements of nucleate and anucleate lineages and the activation of myeloid clones following acute platelet depletion
E. Wojtowicz, Jayna J. Mistry, Vladimir Uzun, C. Hellmich +16 more
2023Genome Biology6 citations Open access
Semantic Scholar
Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells
Sahoko Matsuoka, R. Facchini, T. Luis, J. Carrelha +11 more
2023Blood5 citations Open access
Semantic Scholar
Identification and Age-dependent Increase of Platelet Biased Human Hematopoietic Stem Cells
Merve Aksöz, Grigore-Aristide Gafencu, B. Stoilova, Mario Buono +8 more
2022bioRxiv5 citations Open access
Semantic Scholar
Corrigendum: Structural basis for selective binding of m(6)A RNA by the YTHDC1 YTH domain.
Chao Xu, I. A. Roundtree, T. Weinert, S. Huwiler +24 more
2015Nature Chemical Biology5 citations Open access
Semantic Scholar
Perivascular Niche Cells Sense Thrombocytopenia and Activate Platelet-Biased Hscs in an IL-1 Dependent Manner
T. Luis, Nikolaos Barkas, Alice Giustacchini, Bishan Wu +4 more
2018Experimental Hematology3 citations Open access
Semantic Scholar
Hematopoietic Lineage Diversification, Simplified.
Roy Drissen, C. Nerlov
2016Cell Stem Cell3 citations Open access
Semantic Scholar
To Bi or not to Bi: Acute Erythroid Leukemias and hematopoietic lineage choice.
C. Di Genua, C. Nerlov
2021Experimental Hematology2 citations Open access
Semantic Scholar
Aging of Bone Marrow Microenvironment Promotes Myeloid Bias of Hematopoietic Progenitors and Is a Target in Age-Related Myeloproliferative Neoplasms
Ya-Hsuan Ho, R. del Toro, José Rivera-Torres, Justyna Rak +19 more
2018Blood2 citations Open access
Semantic Scholar

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