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C. Virtanen · SciRah

Researcher profile · Semantic Scholar

C. Virtanen

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C. Virtanen — researcher profile on SciRah

h-index: 34
Works: 102
Citations: 4,742

Most-cited papers

DNA methylation profiles in monozygotic and dizygotic twins
Z. Kaminsky, Thomas Tang, Sun-Chong Wang, Carolyn Ptak +12 more
2009Nature Genetics703 citations
Semantic Scholar
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
M. Sasaki, C. Knobbe, Joshua C. Munger, E. Lind +18 more
2012Nature519 citations Open access
Semantic Scholar
Functional genomic Landscape of Human Breast Cancer drivers, vulnerabilities, and resistance
R. Marcotte, A. Sayad, K. Brown, Felix Sanchez-Garcia +9 more
2016Cell430 citations Open access
Semantic Scholar
Molecular profiling of advanced solid tumors and patient outcomes with genotype-matched clinical trials: the Princess Margaret IMPACT/COMPACT trial
T. Stockley, A. Oza, Hal K. Berman, N. Leighl +26 more
2016Genome Medicine234 citations Open access
Semantic Scholar
Intra- and interindividual epigenetic variation in human germ cells.
J. Flanagan, V. Popendikyte, Natalija Pozdniakovaite, Martha Sobolev +7 more
2006American Journal of Human Genetics233 citations Open access
Semantic Scholar
Global proteomic assessment of the classical protein-tyrosine phosphatome and “redoxome”
R. Karisch, Minerva M. Fernandez, Paul Taylor, C. Virtanen +9 more
2011Cell174 citations Open access
Semantic Scholar
Three-dimensional culture and cAMP signaling promote the maturation of human pluripotent stem cell-derived hepatocytes
S. Ogawa, James Surapisitchat, C. Virtanen, Mina Ogawa +12 more
2013Development157 citations Open access
Semantic Scholar
The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells.
A. Brüstle, D. Brenner, C. Knobbe, P. Lang +7 more
2012Journal of Clinical Investigation125 citations Open access
Semantic Scholar
Two subclasses of lung squamous cell carcinoma with different gene expression profiles and prognosis identified by hierarchical clustering and non-negative matrix factorization
K. Inamura, Takeshi Fujiwara, Y. Hoshida, T. Isagawa +11 more
2005Oncogene104 citations Open access
Semantic Scholar
PTP1B regulates non-mitochondrial oxygen consumption via RNF213 to promote tumour survival during hypoxia
Robert S. Banh, Caterina Iorio, R. Marcotte, Yang Xu +21 more
2016Nature Cell Biology100 citations Open access
Semantic Scholar
Implementation and Outcomes of Virtual Care Across a Tertiary Cancer Center During COVID-19
A. Berlin, M. Lovas, Truong Tran, S. Melwani +15 more
2021JAMA Oncology96 citations Open access
Semantic Scholar
Microarray Analysis of the Infrapatellar Fat Pad in Knee Osteoarthritis: Relationship with Joint Inflammation
R. Gandhi, Mark Takahashi, C. Virtanen, K. Syed +2 more
2011Journal of Rheumatology78 citations Open access
Semantic Scholar
Activating mutations affecting the Dbl homology domain of SOS2 cause Noonan syndrome
Viviana Cordeddu, Jia-Ni C. Yin, Cecilia Gunnarsson, C. Virtanen +35 more
2015Human Mutation77 citations Open access
Semantic Scholar
Plasminogen activator uPA is a direct transcriptional target of the JAG1-Notch receptor signaling pathway in breast cancer.
Mamiko Shimizu, B. Cohen, P. Goldvasser, Hal K. Berman +2 more
2011Cancer Research73 citations
Semantic Scholar
Low malignant potential tumors with micropapillary features are molecularly similar to low-grade serous carcinoma of the ovary.
T. May, C. Virtanen, Monika Sharma, A. Milea +5 more
2010Gynecologic Oncology71 citations
Semantic Scholar
MicroRNA expression profiling of esophageal cancer before and after induction chemoradiotherapy.
Michael Ko, Z. Guan, C. Virtanen, M. Guindi +3 more
2012Annals of Thoracic Surgery58 citations Open access
Semantic Scholar
SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis
Bo Ram Kim, E. Van de Laar, M. Cabanero, Shintaro Tarumi +12 more
2016PLoS Biology50 citations Open access
Semantic Scholar
Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels.
M. Sukhai, M. Misyura, M. Thomas, S. Garg +10 more
2019Journal of Molecular Diagnostics49 citations Open access
Semantic Scholar
GABA promotes β‐cell proliferation, but does not overcome impaired glucose homeostasis associated with diet‐induced obesity
A. Untereiner, Shaaban Abdo, A. Bhattacharjee, H. Gohil +16 more
2018The FASEB Journal49 citations Open access
Semantic Scholar
In Vivo Optical Imaging of Tumor and Microvascular Response to Ionizing Radiation
A. Maeda, M. Leung, L. Conroy, Yonghong Chen +12 more
2012PLoS ONE46 citations Open access
Semantic Scholar
EXOME-WIDE ASSOCIATION STUDY OF PANCREATIC CANCER RISK
R. Grant, R. Denroche, A. Borgida, C. Virtanen +15 more
2017Gastroenterology45 citations Open access
Semantic Scholar
Gene expression differences between psoriasis patients with and without inflammatory arthritis.
R. Pollock, F. Abji, Kun Liang, V. Chandran +3 more
2015Journal of Investigative Dermatology43 citations Open access
Semantic Scholar
PIM kinase isoform specific regulation of MIG6 expression and EGFR signaling in prostate cancer cells
Allan Siu, C. Virtanen, J. Jongstra
2011OncoTarget43 citations Open access
Semantic Scholar
Identification of abrogated pathways in fallopian tube epithelium from BRCA1 mutation carriers
S. George, J. Greenaway, A. Milea, V. Clary +4 more
2011Journal of Pathology42 citations
Semantic Scholar
Ovarian tumour growth is characterized by mevalonate pathway gene signature in an orthotopic, syngeneic model of epithelial ovarian cancer
J. Greenaway, C. Virtanen, Katalin Ősz, T. Révay +4 more
2016OncoTarget41 citations Open access
Semantic Scholar
Effect of topical interferon-γ gene therapy using gemini nanoparticles on pathophysiological markers of cutaneous scleroderma in Tsk/+ mice
I. Badea, C. Virtanen, R. Verrall, Alan M. Rosenberg +1 more
2011Gene Therapy41 citations
Semantic Scholar
Molecular Profiling and Clinical Outcome of High-Grade Serous Ovarian Cancer Presenting with Low- versus High-Volume Ascites
T. Feigenberg, B. Clarke, C. Virtanen, A. Plotkin +6 more
2014BioMed Research International38 citations Open access
Semantic Scholar
Altered expression of inflammation-associated genes in oviductal cells following follicular fluid exposure: Implications for ovarian carcinogenesis
Angela Lau, A. Kollara, E. S. St John, A. Tone +4 more
2014Experimental biology and medicine36 citations
Semantic Scholar
Discovery of biomarkers of endometrial receptivity through a minimally invasive approach: a validation study with implications for assisted reproduction.
C. Chan, C. Virtanen, N. Winegarden, T. Colgan +2 more
2013Fertility and Sterility36 citations
Semantic Scholar
SHP2 Is Required for BCR-ABL1-Induced Hematologic Neoplasia
Sheng-Qing Gu, A. Sayad, G. Chan, Wentian Yang +4 more
2017Leukemia34 citations Open access
Semantic Scholar
Identification of a novel antigen-presenting cell population modulating antiinfluenza type 2 immunity
Jae-Kwang Yoo, C. Galligan, D. Burke, C. Virtanen +1 more
2009Journal of Experimental Medicine34 citations Open access
Semantic Scholar
Microarray-based DNA methylation profiling: technology and applications
A. Schumacher, Philipp Kapranov, Z. Kaminsky, J. Flanagan +7 more
2006Nucleic Acids Research34 citations Open access
Semantic Scholar
Prolonged Postovulatory Proinflammatory Signaling in the Fallopian Tube Epithelium May Be Mediated through a BRCA1/DAB2 Axis
A. Tone, C. Virtanen, P. Shaw, T. Brown
2012Clinical Cancer Research32 citations Open access
Semantic Scholar
A Genomically Characterized Collection of High-Grade Serous Ovarian Cancer Xenografts for Preclinical Testing.
P. Cybulska, J. Stewart, A. Sayad, C. Virtanen +5 more
2018American Journal of Pathology28 citations Open access
Semantic Scholar
Evidence for a multipotent mammary progenitor with pregnancy-specific activity
Alice S Kaanta, C. Virtanen, L. Selfors, J. Brugge +1 more
2013Breast Cancer Research26 citations Open access
Semantic Scholar
Clinical uses of microarrays in cancer research.
C. Virtanen, J. Woodgett
2008Methods in Molecular Medicine26 citations Open access
Semantic Scholar
CanDIG: Federated network across Canada for multi-omic and health data discovery and analysis
L. Dursi, Z. Bozoky, R. de Borja, Haoyuan Li +27 more
2021Cell Genomics25 citations Open access
Semantic Scholar
Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1.
Sheng-Qing Gu, W. Chan, Golam Mohi, Joel C. Rosenbaum +6 more
2016Blood25 citations Open access
Semantic Scholar
Identification of MEF2-regulated genes during muscle differentiation.
J. Paris, C. Virtanen, Zhibin Lu, Mark Takahashi
2004Physiological Genomics25 citations Open access
Semantic Scholar
The use of personal health information outside the circle of care: consent preferences of patients from an academic health care institution
S. Tosoni, I. Voruganti, K. Lajkosz, F. Habal +6 more
2021BMC Medical Ethics24 citations Open access
Semantic Scholar
Human ortholog of Drosophila Melted impedes SMAD2 release from TGF-β receptor I to inhibit TGF-β signaling
Premalatha Shathasivam, A. Kollara, M. Ringuette, C. Virtanen +2 more
2015Proceedings of the National Academy of Sciences of the United States of America23 citations Open access
Semantic Scholar
Decreased progesterone receptor isoform expression in luteal phase fallopian tube epithelium and high-grade serous carcinoma
A. Tone, C. Virtanen, P. Shaw, T. Brown
2011Endocrine-Related Cancer23 citations Open access
Semantic Scholar
Patient consent preferences on sharing personal health information during the COVID-19 pandemic: “the more informed we are, the more likely we are to help”
S. Tosoni, I. Voruganti, K. Lajkosz, Shahbano Mustafa +7 more
2022BMC Medical Ethics22 citations Open access
Semantic Scholar
ABC: a tool to identify SNVs causing allele-specific transcription factor binding from ChIP-Seq experiments
Swneke D. Bailey, C. Virtanen, B. Haibe-Kains, M. Lupien
2015Bioinform.22 citations Open access
Semantic Scholar
A clinical laboratory–developed LSC17 stemness score assay for rapid risk assessment of patients with acute myeloid leukemia
S. W. Ng, T. Murphy, I. King, Tong Zhang +17 more
2021Blood Advances21 citations Open access
Semantic Scholar
Myxoid smooth muscle neoplasia of the uterus: comprehensive analysis by next-generation sequencing and nucleic acid hybridization
Ju-Yoon Yoon, A. Mariño-Enríquez, N. Stickle, R. de Borja +7 more
2019Modern Pathology21 citations Open access
Semantic Scholar
Essential requirements for establishing and operating data trusts: practical guidance co-developed by representatives from fifteen canadian organizations and initiatives
P. A. Paprica, E. Sutherland, Andrea Smith, M. Brudno +10 more
2020International Journal of Population Data Science20 citations Open access
Semantic Scholar
Impact of neoadjuvant chemotherapy on somatic mutation status in high-grade serous ovarian carcinoma
Z. Marchocki, A. Tone, C. Virtanen, R. de Borja +3 more
2021Journal of Ovarian Research14 citations Open access
Semantic Scholar
Gene array analysis of embryonic- versus adult-derived hypothalamic NPY-expressing cell lines.
S. Dhillon, Sarah Gingerich, C. Virtanen, D. Belsham
2012Molecular and Cellular Endocrinology13 citations
Semantic Scholar
BRCA1 Mutation Status and Follicular Fluid Exposure Alters NFκB Signaling and ISGylation in Human Fallopian Tube Epithelial Cells12
Julia Hollingsworth, Angela Lau, A. Tone, A. Kollara +9 more
2018Neoplasia11 citations Open access
Semantic Scholar

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