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A. Brüstle · SciRah

Researcher profile · Semantic Scholar

A. Brüstle

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A. Brüstle — researcher profile on SciRah

h-index: 29
Works: 61
Citations: 6,198

Most-cited papers

Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression.
I. Harris, A. Treloar, S. Inoue, M. Sasaki +22 more
2015Cancer Cell937 citations Open access
Semantic Scholar
The development of inflammatory TH-17 cells requires interferon-regulatory factor 4
A. Brüstle, Sylvia Heink, M. Huber, Christine Rosenplänter +6 more
2007Nature Immunology714 citations
Semantic Scholar
IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics
M. Sasaki, C. Knobbe, Joshua C. Munger, E. Lind +18 more
2012Nature519 citations Open access
Semantic Scholar
Glutathione Primes T Cell Metabolism for Inflammation
T. Mak, M. Grusdat, G. Duncan, Catherine Dostert +19 more
2017Immunity453 citations Open access
Semantic Scholar
Natural killer cell activation enhances immune pathology and promotes chronic infection by limiting CD8+ T-cell immunity
P. Lang, K. Lang, Hai-Feng C. Xu, M. Grusdat +20 more
2011Proceedings of the National Academy of Sciences of the United States of America322 citations Open access
Semantic Scholar
IRF4 is essential for IL-21-mediated induction, amplification, and stabilization of the Th17 phenotype
M. Huber, A. Brüstle, Katharina Reinhard, Anna Guralnik +4 more
2008Proceedings of the National Academy of Sciences of the United States of America303 citations Open access
Semantic Scholar
IL-17A secretion by CD8+ T cells supports Th17-mediated autoimmune encephalomyelitis.
M. Huber, Sylvia Heink, A. Pagenstecher, Katharina Reinhard +16 more
2013Journal of Clinical Investigation257 citations Open access
Semantic Scholar
A Th17‐like developmental process leads to CD8+ Tc17 cells with reduced cytotoxic activity
M. Huber, Sylvia Heink, H. Grothe, Anna Guralnik +7 more
2009European Journal of Immunology257 citations Open access
Semantic Scholar
Lymphocyte-derived ACh regulates local innate but not adaptive immunity
Colin Reardon, G. Duncan, A. Brüstle, D. Brenner +5 more
2013Proceedings of the National Academy of Sciences of the United States of America218 citations Open access
Semantic Scholar
IL-27 inhibits the development of regulatory T cells via STAT3.
M. Huber, Vera Steinwald, Anna Guralnik, A. Brüstle +4 more
2008International Immunology202 citations Open access
Semantic Scholar
Transcription factor IRF4 determines germinal center formation through follicular T-helper cell differentiation
Nadine Bollig, A. Brüstle, K. Kellner, Waltraud Ackermann +15 more
2012Proceedings of the National Academy of Sciences of the United States of America197 citations Open access
Semantic Scholar
Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2
Alicia S. Wilson, Katrina L. Randall, J. Pettitt, J. Ellyard +6 more
2022Nature Communications194 citations Open access
Semantic Scholar
The transcription factor IFN regulatory factor-4 controls experimental colitis in mice via T cell-derived IL-6.
J. Mudter, L. Amoussina, Mirjam Schenk, Jing-Ling Yu +14 more
2008Journal of Clinical Investigation137 citations Open access
Semantic Scholar
Deficiency of MALT1 Paracaspase Activity Results in Unbalanced Regulatory and Effector T and B Cell Responses Leading to Multiorgan Inflammation
F. Bornancin, F. Renner, Ratiba Touil, Heiko Sic +26 more
2015Journal of Immunology127 citations Open access
Semantic Scholar
The NF-κB regulator MALT1 determines the encephalitogenic potential of Th17 cells.
A. Brüstle, D. Brenner, C. Knobbe, P. Lang +7 more
2012Journal of Clinical Investigation125 citations Open access
Semantic Scholar
IL-17-producing γδ T cells switch migratory patterns between resting and activated states
Duncan R. McKenzie, Ervin E. Kara, Cameron R. Bastow, Timona S Tyllis +11 more
2017Nature Communications117 citations Open access
Semantic Scholar
IRF4 regulates IL‐17A promoter activity and controls ROR&ggr;t‐dependent Th17 colitis in vivo
J. Mudter, Jing-Ling Yu, C. Zufferey, A. Brüstle +9 more
2011Inflammatory Bowel Diseases115 citations Open access
Semantic Scholar
Thymic stromal lymphopoetin-induced expression of the endogenous inhibitory enzyme SLPI mediates recovery from colonic inflammation
Colin Reardon, M. Lechmann, A. Brüstle, M. Gareau +4 more
2011Immunity112 citations Open access
Semantic Scholar
The interaction between caveolin-1 and Rho-GTPases promotes metastasis by controlling the expression of alpha5-integrin and the activation of Src, Ras and Erk
E. Arpaia, H. Blaser, M. Quintela-Fandino, G. Duncan +12 more
2011Oncogene109 citations Open access
Semantic Scholar
TAp73 is required for spermatogenesis and the maintenance of male fertility
S. Inoue, R. Tomasini, A. Rufini, A. Elia +17 more
2014Proceedings of the National Academy of Sciences of the United States of America98 citations Open access
Semantic Scholar
Chronic viral infection promotes sustained Th1-derived immunoregulatory IL-10 via BLIMP-1.
I. Parish, Heather D. Marshall, Matthew M. Staron, P. Lang +9 more
2014Journal of Clinical Investigation90 citations Open access
Semantic Scholar
Glutathione Primes T Cell Metabolism for Inflammation.
T. Mak, M. Grusdat, G. Duncan, Catherine Dostert +19 more
2017Immunity86 citations Open access
Semantic Scholar
GSTO1-1 plays a pro-inflammatory role in models of inflammation, colitis and obesity
D. Menon, A. Innes, A. Oakley, J. Dahlstrom +15 more
2017Scientific Reports54 citations Open access
Semantic Scholar
MALT1 is an intrinsic regulator of regulatory T cells
A. Brüstle, D. Brenner, CB Knobbe-Thomsen, M. Cox +3 more
2015Cell Death and Differentiation54 citations Open access
Semantic Scholar
2-Methoxyestradiol inhibits experimental autoimmune encephalomyelitis through suppression of immune cell activation
G. Duncan, D. Brenner, M. Tusche, A. Brüstle +6 more
2012Proceedings of the National Academy of Sciences of the United States of America51 citations Open access
Semantic Scholar
Toso controls encephalitogenic immune responses by dendritic cells and regulatory T cells
D. Brenner, A. Brüstle, G. Lin, P. Lang +12 more
2014Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Crucial role for TNF receptor-associated factor 2 (TRAF2) in regulating NFκB2 signaling that contributes to autoimmunity
Wen-Jye Lin, Yu-Wen Su, Yong-Chen Lu, Z. Hao +5 more
2011Proceedings of the National Academy of Sciences of the United States of America47 citations Open access
Semantic Scholar
Enhanced TCR-induced Apoptosis in Interferon Regulatory Factor 4–deficient CD4+ Th Cells
M. Lohoff, H. Mittrücker, A. Brüstle, F. Sommer +5 more
2004Journal of Experimental Medicine45 citations Open access
Semantic Scholar
A multimorphic mutation in IRF4 causes human autosomal dominant combined immunodeficiency
O. Fornes, Alicia Jia, H. Kuehn, Qing Min +98 more
2023Science immunology39 citations
Semantic Scholar
Immunity against Moraxella catarrhalis requires guanylate‐binding proteins and caspase‐11‐NLRP3 inflammasomes
Daniel Enosi Tuipulotu, Shou-Ya Feng, Abhimanu Pandey, Anyang Zhao +25 more
2023EMBO Journal29 citations Open access
Semantic Scholar
Antigen receptor-mediated depletion of FOXP3 in induced regulatory T-lymphocytes via PTPN2 and FOXO1
E. Bothur, H. Raifer, C. Haftmann, Anna-Barbara Stittrich +18 more
2015Nature Communications29 citations Open access
Semantic Scholar
Autophagy-independent functions of UVRAG are essential for peripheral naive T-cell homeostasis
S. Afzal, Z. Hao, M. Itsumi, Yasser Abouelkheer +13 more
2015Proceedings of the National Academy of Sciences of the United States of America25 citations Open access
Semantic Scholar
Toso regulates differentiation and activation of inflammatory dendritic cells during persistence-prone virus infection
Pa Lang, A. Meryk, AA Pandyra, D. Brenner +18 more
2014Cell Death and Differentiation23 citations Open access
Semantic Scholar
Flexible polygon‐mirror based laser scanning microscope platform for multiphoton in‐vivo imaging
Yang Li, V. Gautam, A. Brüstle, I. Cockburn +5 more
2017Journal of Biophotonics19 citations
Semantic Scholar
The role of machine learning in developing non-magnetic resonance imaging based biomarkers for multiple sclerosis: a systematic review
Md. Zakir Hossain, E. Daskalaki, A. Brüstle, J. Desborough +2 more
2022BMC Medical Informatics and Decision Making15 citations Open access
Semantic Scholar
High contrast imaging and flexible photomanipulation for quantitative in vivo multiphoton imaging with polygon scanning microscope
Yongxiao Li, S. Montague, A. Brüstle, Xue-Fei He +4 more
2018Journal of Biophotonics10 citations Open access
Semantic Scholar
Correction for Petrič et al., Dicyanovinylnaphthalenes for neuroimaging of amyloids and relationships of electronic structures and geometries to binding affinities
Colin Reardon, G. Duncan, A. Brüstle, D. Brenner +5 more
2013Proceedings of the National Academy of Sciences of the United States of America6 citations Open access
Semantic Scholar
Aufbau mittelständischer Strukturen in Polen, Ungarn, der Tschechischen Republik und der Slowakischen Republik
Bernhard Lageman, W. Friedrich, R. Dohrn, A. Brüstle +3 more
19946 citations
Semantic Scholar
Measuring Fatigue in Multiple Sclerosis: A Rapid Review
Tergel Namsrai, A. Parkinson, Richard Burns, Geoffrey Herkes +8 more
2025Patient5 citations Open access
Semantic Scholar
A hyperactive mutant of interferon‐regulatory factor 4
Cholho Kang, E. Hartmann, L. Menke, Daniel Staudenraus +8 more
2018European Journal of Immunology5 citations Open access
Semantic Scholar
Quantification of Neutrophil Extracellular Traps Isolated From Mouse Tissues
Rebecca L. Buckland, Alicia S. Wilson, A. Brüstle
2020Current Protocols in Mouse Biology3 citations
Semantic Scholar
Advanced immunophenotyping of lymphocyte and monocyte subsets in healthy Australian adults using a novel spectral flow cytometry panel
Ainsley R. Davies, Kristy Kwong, Zhijia Yu, Koula E M Diamand +17 more
2025Frontiers in Immunology2 citations Open access
Semantic Scholar
A randomised controlled trial of physical activity and cognitive training in older adults: the PhABHeaD study
N. Cherbuin, Joseph M. Northey, E. Walsh, Richard Burns +10 more
2026Trials1 citations Open access
Semantic Scholar
Disentangling Blood-Based Markers of Multiple Sclerosis Through Machine Learning: An Evaluation Study
Robin Vlieger, Mousumi Rizia, Abolfazl Amjadipour, Nicolas Cherbuin +2 more
2025medRxiv1 citations Open access
Semantic Scholar
Optimising Personalised Medical Insights by Introducing a Scalable Health Informatics Application for Sensor Data Extraction, Preprocessing, and Analysis.
Chirath Hettiarachchi, Robin Vlieger, Wen-Bo Ge, Deborah Apthorp +3 more
2024Studies in Health Technology and Informatics1 citations Open access
Semantic Scholar
Author response for "Protection from EAE in DOCK8 mutant mice occurs despite increased Th17 cell frequencies in the periphery"
Alicia S. Wilson, Hsei Di Law, Christiane B. Knobbe-Thomsen, Conor J. Kearney +7 more
20181 citations
Semantic Scholar
Immature CD10low blood neutrophils are enriched in people with multiple sclerosis
Luke W. Garratt, Alice A. White, C. Schofield, J. Leffler +5 more
2026Frontiers in Immunology0 citations Open access
Semantic Scholar
RUNX2 is a cell-intrinsic brake on Th17 pathogenicity driven by neutrophil extracellular traps
Caleb Wong Han, Aaron Han Heng, Gabrielle T. Belz, A. Brüstle +2 more
2025bioRxiv0 citations
Semantic Scholar
Co-Designing a Multiple Sclerosis Fatigue App
Susan Hansen, Michelle Pickrell, Zhe-Yuan Xu, Richard Burns +9 more
2025Medinfo0 citations Open access
Semantic Scholar
Acceptability and Feasibility of the English Version of Elevida, a Self-Guided Online Fatigue Intervention for People With Multiple Sclerosis.
J. Lane, Carmel Poyser, Yixuan Zhao, Robyn Lucas +8 more
2024International Journal of MS Care0 citations Open access
Semantic Scholar

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T. Mak×18
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D. Brenner×14
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M. Lohoff×12
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M. Huber×8
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G. Duncan — researcher profile on SciRah

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P. Ohashi — researcher profile on SciRah

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P. Lang — researcher profile on SciRah

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M. Cox — researcher profile on SciRah

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