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Peter M. Snyder · SciRah

Researcher profile · Semantic Scholar

Peter M. Snyder

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Peter M. Snyder — researcher profile on SciRah

h-index: 42
Works: 86
Citations: 6,688

Most-cited papers

Serum and Glucocorticoid-regulated Kinase Modulates Nedd4-2-mediated Inhibition of the Epithelial Na+Channel*
Peter M. Snyder, Diane R. Olson, Brittany Thomas
2002Journal of Biological Chemistry465 citations Open access
Semantic Scholar
Mechanism by which Liddle's syndrome mutations increase activity of a human epithelial Na+ channel.
Peter M. Snyder, M. Price, F. McDonald, Christopher M Adams +4 more
1995Cell419 citations Open access
Semantic Scholar
Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons
C. Benson, Jinghui Xie, J. Wemmie, M. Price +3 more
2002Proceedings of the National Academy of Sciences of the United States of America373 citations Open access
Semantic Scholar
Cloning and Expression of a Novel Human Brain Na Channel (*)
M. Price, Peter M. Snyder, M. Welsh
1996Journal of Biological Chemistry321 citations Open access
Semantic Scholar
Electrophysiological and Biochemical Evidence That DEG/ENaC Cation Channels Are Composed of Nine Subunits*
Peter M. Snyder, Chun Cheng, L. Prince, J. Rogers +1 more
1998Journal of Biological Chemistry251 citations Open access
Semantic Scholar
cAMP and Serum and Glucocorticoid-inducible Kinase (SGK) Regulate the Epithelial Na+ Channel through Convergent Phosphorylation of Nedd4-2*
Peter M. Snyder, Diane R. Olson, Rajesh Kabra, Rui-Feng Zhou +1 more
2004Journal of Biological Chemistry239 citations Open access
Semantic Scholar
Minireview: regulation of epithelial Na+ channel trafficking.
Peter M. Snyder
2005Endocrinology232 citations Open access
Semantic Scholar
Membrane topology of the amiloride-sensitive epithelial sodium channel.
Peter M. Snyder, F. McDonald, J. Stokes, M. Welsh
1994Journal of Biological Chemistry226 citations Open access
Semantic Scholar
Nedd4-2 Catalyzes Ubiquitination and Degradation of Cell Surface ENaC*
Rui-Feng Zhou, Saumil V Patel, Peter M. Snyder
2007Journal of Biological Chemistry218 citations Open access
Semantic Scholar
Nedd4 Mediates Agonist-dependent Ubiquitination, Lysosomal Targeting, and Degradation of the β2-Adrenergic Receptor*
Sudha K. Shenoy, K. Xiao, Vidya Venkataramanan, Peter M. Snyder +2 more
2008Journal of Biological Chemistry197 citations Open access
Semantic Scholar
The epithelial Na+ channel: cell surface insertion and retrieval in Na+ homeostasis and hypertension.
Peter M. Snyder
2002Endocrine reviews194 citations Open access
Semantic Scholar
Inhibition of the Epithelial Na+ Channel by Interaction of Nedd4 with a PY Motif Deleted in Liddle’s Syndrome*
C. Goulet, K. Volk, Christopher M Adams, L. Prince +2 more
1998Journal of Biological Chemistry190 citations Open access
Semantic Scholar
DEG/ENaC ion channels involved in sensory transduction are modulated by cold temperature
C. Askwith, C. Benson, M. Welsh, Peter M. Snyder
2001Proceedings of the National Academy of Sciences of the United States of America187 citations Open access
Semantic Scholar
Relative Contribution of Nedd4 and Nedd4-2 to ENaC Regulation in Epithelia Determined by RNA Interference*
Peter M. Snyder, Jennifer C. Steines, Diane R. Olson
2004Journal of Biological Chemistry160 citations Open access
Semantic Scholar
Liddle's syndrome mutations disrupt cAMP-mediated translocation of the epithelial Na(+) channel to the cell surface.
Peter M. Snyder
2000Journal of Clinical Investigation157 citations Open access
Semantic Scholar
Mutations of KCNJ10 together with mutations of SLC26A4 cause digenic nonsyndromic hearing loss associated with enlarged vestibular aqueduct syndrome.
Tao Yang, J. Gurrola, Hao Wu, Sui M Chiu +3 more
2009American Journal of Human Genetics156 citations Open access
Semantic Scholar
Salt-sensitive hypertension and cardiac hypertrophy in mice deficient in the ubiquitin ligase Nedd4-2.
P. Shi, Xiao R. Cao, Eileen M Sweezer, Thomas S. Kinney +10 more
2008AJP - Renal Physiology154 citations Open access
Semantic Scholar
Liddle's syndrome mutations increase Na+ transport through dual effects on epithelial Na+ channel surface expression and proteolytic cleavage.
Kristin K. Knight, Diane R. Olson, Rui-Feng Zhou, Peter M. Snyder
2006Proceedings of the National Academy of Sciences of the United States of America150 citations
Semantic Scholar
The kidney-specific WNK1 isoform is induced by aldosterone and stimulates epithelial sodium channel-mediated Na+ transport.
A. Náray-Fejes-Tóth, Peter M. Snyder, G. Fejes-Tóth
2004Proceedings of the National Academy of Sciences of the United States of America145 citations Open access
Semantic Scholar
Number of Subunits Comprising the Epithelial Sodium Channel*
S. Eskandari, Peter M. Snyder, M. Kreman, G. Zampighi +2 more
1999Journal of Biological Chemistry145 citations Open access
Semantic Scholar
Interactions between Subunits of the Human Epithelial Sodium Channel*
Christopher M Adams, Peter M. Snyder, M. Welsh
1997Journal of Biological Chemistry138 citations Open access
Semantic Scholar
Genetic variants in the epithelial sodium channel in relation to aldosterone and potassium excretion and risk for hypertension.
W. Ambrosius, Laura J. Bloem, Li-Fen Zhou, J. Rebhun +4 more
1999HYPERTENSION121 citations Open access
Semantic Scholar
Nedd4-2 Phosphorylation Induces Serum and Glucocorticoid-regulated Kinase (SGK) Ubiquitination and Degradation*
Rui-Feng Zhou, Peter M. Snyder
2005Journal of Biological Chemistry117 citations Open access
Semantic Scholar
A Pore Segment in DEG/ENaC Na+ Channels*
Peter M. Snyder, Diane R. Olson, Daniel B. Bucher
1999Journal of Biological Chemistry112 citations Open access
Semantic Scholar
Nedd4-2 Induces Endocytosis and Degradation of Proteolytically Cleaved Epithelial Na+ Channels*
Rajesh Kabra, Kristin K. Knight, Rui-Feng Zhou, Peter M. Snyder
2008Journal of Biological Chemistry102 citations Open access
Semantic Scholar
Regulation of Epithelial Sodium Channel Trafficking by Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9)*
Vikas Sharotri, Daniel M. Collier, Diane R. Olson, Rui-Feng Zhou +1 more
2012Journal of Biological Chemistry95 citations Open access
Semantic Scholar
Extracellular Protons Regulate Human ENaC by Modulating Na+ Self-inhibition*
Daniel M. Collier, Peter M. Snyder
2009Journal of Biological Chemistry91 citations Open access
Semantic Scholar
Multiple WW Domains, but Not the C2 Domain, Are Required for Inhibition of the Epithelial Na+ Channel by Human Nedd4*
Peter M. Snyder, Diane R. Olson, F. McDonald, Daniel B. Bucher
2001Journal of Biological Chemistry90 citations Open access
Semantic Scholar
Gating Induces a Conformational Change in the Outer Vestibule of Enac
Peter M. Snyder, Daniel B. Bucher, Diane R. Olson
2000The Journal of General Physiology86 citations Open access
Semantic Scholar
Protons Activate Brain Na+ Channel 1 by Inducing a Conformational Change That Exposes a Residue Associated with Neurodegeneration*
Christopher M Adams, Peter M. Snyder, M. Price, M. Welsh
1998Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Extracellular Chloride Regulates the Epithelial Sodium Channel*
Daniel M. Collier, Peter M. Snyder
2009Journal of Biological Chemistry73 citations Open access
Semantic Scholar
Down-Regulating Destruction: Phosphorylation Regulates the E3 Ubiquitin Ligase Nedd4-2
Peter M. Snyder
2009Science Signaling71 citations
Semantic Scholar
Oxidant regulated inter-subunit disulfide bond formation between ASIC1a subunits
Xiang-ming Zha, Run-Ping Wang, Daniel M. Collier, Peter M. Snyder +2 more
2009Proceedings of the National Academy of Sciences of the United States of America68 citations Open access
Semantic Scholar
Ubiquitin-protein ligase WWP2 binds to and downregulates the epithelial Na(+) channel.
F. McDonald, A. Western, J. McNeil, Brittany Thomas +2 more
2002AJP - Renal Physiology65 citations
Semantic Scholar
Paradoxical Stimulation of a DEG/ENaC Channel by Amiloride*
Christopher M Adams, Peter M. Snyder, M. Welsh
1999Journal of Biological Chemistry64 citations Open access
Semantic Scholar
Alternate promoters and variable splicing lead to hNedd4-2 isoforms with a C2 domain and varying number of WW domains.
Omar A. Itani, Jason R. Campbell, J. Herrero, Peter M. Snyder +1 more
2003AJP - Renal Physiology61 citations
Semantic Scholar
Human Nedd4 interacts with the human epithelial Na+ channel: WW3 but not WW1 binds to Na+-channel subunits.
T. Farr, Sarah J. Coddington-Lawson, Peter M. Snyder, F. McDonald
2000Biochemical Journal55 citations Open access
Semantic Scholar
N-glycosylation of Acid-sensing Ion Channel 1a Regulates its Trafficking and Acidosis-induced Spine Remodeling
Lan Jing, Xiang-Ping Chu, Yu-Qing Jiang, Daniel M. Collier +4 more
2012Journal of Neuroscience52 citations Open access
Semantic Scholar
Identification of Epithelial Na+ Channel (ENaC) Intersubunit Cl− Inhibitory Residues Suggests a Trimeric αγβ Channel Architecture
Daniel M. Collier, Peter M. Snyder
2010Journal of Biological Chemistry50 citations Open access
Semantic Scholar
Assembly of the Epithelial Na+ Channel Evaluated Using Sucrose Gradient Sedimentation Analysis*
Chun Cheng, L. Prince, Peter M. Snyder, M. Welsh
1998Journal of Biological Chemistry50 citations Open access
Semantic Scholar
Ubiquitin-specific Peptidase 8 (USP8) Regulates Endosomal Trafficking of the Epithelial Na+ Channel*
Rui-Feng Zhou, V. Tomkovicz, Phillip L. Butler, Luis A Ochoa +2 more
2013Journal of Biological Chemistry43 citations Open access
Semantic Scholar
Intracellular Sodium Regulates Proteolytic Activation of the Epithelial Sodium Channel*
Kristin K. Knight, Danielle M. Wentzlaff, Peter M. Snyder
2008Journal of Biological Chemistry42 citations Open access
Semantic Scholar
Hrs Controls Sorting of the Epithelial Na+ Channel between Endosomal Degradation and Recycling Pathways*
Rui-Feng Zhou, Rajesh Kabra, Diane R. Olson, R. Piper +1 more
2010Journal of Biological Chemistry39 citations Open access
Semantic Scholar
Interaction of Serum- and Glucocorticoid Regulated Kinase 1 (SGK1) with the WW-Domains of Nedd4-2 Is Required for Epithelial Sodium Channel Regulation
D. Wiemuth, J. Lott, Kevin Ly, Ying Ke +3 more
2010PLoS ONE38 citations Open access
Semantic Scholar
Intersubunit conformational changes mediate epithelial sodium channel gating
Daniel M. Collier, V. Tomkovicz, Zerubbabel J. Peterson, C. Benson +1 more
2014The Journal of General Physiology34 citations Open access
Semantic Scholar
Acetylation Stimulates the Epithelial Sodium Channel by Reducing Its Ubiquitination and Degradation*
Phillip L. Butler, A. Staruschenko, Peter M. Snyder
2015Journal of Biological Chemistry32 citations Open access
Semantic Scholar
The Drosophila Gene CheB42a Is a Novel Modifier of Deg/ENaC Channel Function
Y. Ben-Shahar, B. Lu, Daniel M. Collier, Peter M. Snyder +2 more
2010PLoS ONE32 citations Open access
Semantic Scholar
An evolutionarily conserved N-terminal Sgk1 variant with enhanced stability and improved function.
Nandita S. Raikwar, Peter M. Snyder, Christie P. Thomas
2008AJP - Renal Physiology29 citations Open access
Semantic Scholar
A Region Directly Following the Second Transmembrane Domain in γENaC Is Required for Normal Channel Gating*
Rachell E. Booth, Q. Tong, J. Medina, Peter M. Snyder +2 more
2003Journal of Biological Chemistry27 citations Open access
Semantic Scholar
Regulation of Cardiac ATP-sensitive Potassium Channel Surface Expression by Calcium/Calmodulin-dependent Protein Kinase II*
Ana Sierra, Zhiyong Zhu, Nicolas Sapay, Vikas Sharotri +10 more
2012Journal of Biological Chemistry24 citations Open access
Semantic Scholar

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M. Welsh×13
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M. Welsh — researcher profile on SciRah
Diane R. Olson×10
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Diane R. Olson — researcher profile on SciRah
Rui-Feng Zhou×8
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Rui-Feng Zhou — researcher profile on SciRah
Daniel M. Collier×8
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Daniel M. Collier — researcher profile on SciRah

×6

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F. McDonald — researcher profile on SciRah

Christopher M Adams×5

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Christopher M Adams — researcher profile on SciRah

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M. Price — researcher profile on SciRah

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J. Stokes — researcher profile on SciRah

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C. Benson — researcher profile on SciRah

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L. Prince — researcher profile on SciRah

Rajesh Kabra×3

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Rajesh Kabra — researcher profile on SciRah

Kristin K. Knight×3

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Kristin K. Knight — researcher profile on SciRah