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A. Jacob · SciRah

Researcher profile · Semantic Scholar

A. Jacob

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A. Jacob — researcher profile on SciRah

h-index: 25
Works: 47
Citations: 1,940

Most-cited papers

Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial
Jing He, Ruijun Zhang, M. Shao, Xiao-Zhen Zhao +27 more
2019Annals of the Rheumatic Diseases297 citations Open access
Semantic Scholar
TNF is a key mediator of septic encephalopathy acting through its receptor, TNF receptor-1.
J. Alexander, A. Jacob, Patrick N. Cunningham, Lauren K Hensley +1 more
2008Neurochemistry International229 citations Open access
Semantic Scholar
C5a alters blood‐brain barrier integrity in experimental lupus
A. Jacob, B. Hack, E. Chiang, Joe G. N. Garcia +2 more
2010The FASEB Journal129 citations Open access
Semantic Scholar
‘Exchange rates, inflation, and the sterilization problem: Germany, 1975–1981’ by M. Obstfeld
A. Jacob
1983100 citations
Semantic Scholar
Efficacy and Safety of Low-Dose Interleukin 2 for Primary Sjögren Syndrome
Jing He, Jiali Chen, M. Miao, Ruijun Zhang +35 more
2022JAMA Network Open82 citations Open access
Semantic Scholar
Septic encephalopathy: inflammation in man and mouse.
A. Jacob, J. Brorson, J. Alexander
2011Neurochemistry International79 citations
Semantic Scholar
Complement and blood-brain barrier integrity.
A. Jacob, J. Alexander
2014Molecular Immunology76 citations
Semantic Scholar
The role of the complement cascade in endotoxin-induced septic encephalopathy
A. Jacob, Lauren K Hensley, Bryan D. Safratowich, R. Quigg +1 more
2007Laboratory Investigation75 citations Open access
Semantic Scholar
Inhibition of NF-kappaB-dependent Bcl-xL expression by clusterin promotes albumin-induced tubular cell apoptosis.
O. Takase, A. Minto, T. Puri, Patrick N. Cunningham +3 more
2008Kidney International70 citations Open access
Semantic Scholar
Complement-Dependent Apoptosis and Inflammatory Gene Changes in Murine Lupus Cerebritis1
J. Alexander, A. Jacob, Li-Hua Bao, R. Macdonald +1 more
2005Journal of Immunology66 citations Open access
Semantic Scholar
*C5a/CD88 signaling alters blood-brain barrier integrity in lupus through NFκb
A. Jacob, B. Hack, Peili Chen, R. Quigg +1 more
2011Journal of Neurochemistry63 citations Open access
Semantic Scholar
Inhibition of C5a receptor alleviates experimental CNS lupus
A. Jacob, B. Hack, T. Bai, J. Brorson +2 more
2010Journal of Neuroimmunology54 citations Open access
Semantic Scholar
Mouse podocyte complement factor H: the functional analog to human complement receptor 1.
J. Alexander, Ying Wang, A. Chang, A. Jacob +4 more
2007Journal of the American Society of Nephrology53 citations
Semantic Scholar
C3aR inhibition reduces neurodegeneration in experimental lupus
A. Jacob, Li-Hua Bao, J. Brorson, R. Quigg +1 more
2009Lupus50 citations Open access
Semantic Scholar
Absence of functional alternative complement pathway alleviates lupus cerebritis
J. Alexander, A. Jacob, P. Vezina, Hideharu Sekine +2 more
2007European Journal of Immunology49 citations Open access
Semantic Scholar
Retinoic acid-mediated activation of HNF-3α during EC stem cell differentiation
A. Jacob, S. Budhiraja, X. Qian, D. Clevidence +2 more
199444 citations Open access
Semantic Scholar
Curcumin alleviates immune‐complex‐mediated glomerulonephritis in factor‐H‐deficient mice
A. Jacob, L. Chaves, Michael T. Eadon, A. Chang +2 more
2013Immunology40 citations Open access
Semantic Scholar
Local Complement Factor H protects kidney endothelial cell structure and function.
S. Mahajan, A. Jacob, Anju Kelkar, A. Chang +4 more
2021Kidney International38 citations Open access
Semantic Scholar
Lupus: The microbiome angle.
R. Yacoub, A. Jacob, Josette J. Wlaschin, Matthew McGregor +2 more
2017Immunobiology30 citations
Semantic Scholar
Complement: functions, location, and implications
S. Kareem, A. Jacob, John Mathew, R. Quigg +1 more
2023Immunology29 citations Open access
Semantic Scholar
Transcriptional profiling reveals that C5a alters microRNA in brain endothelial cells
Michael T. Eadon, A. Jacob, Patrick N. Cunningham, Richard J. Quigg +2 more
2014Immunology29 citations Open access
Semantic Scholar
Distinct and separable roles of the complement system in factor H-deficient bone marrow chimeric mice with immune complex disease.
J. Alexander, O. Aneziokoro, A. Chang, B. Hack +6 more
2006Journal of the American Society of Nephrology28 citations Open access
Semantic Scholar
Double negative T cells, a potential biomarker for systemic lupus erythematosus
J. Alexander, A. Jacob, A. Chang, R. Quigg +1 more
2020Precision Clinical Medicine27 citations Open access
Semantic Scholar
The HNF-3α Transcription Factor Is a Primary Target for Retinoic Acid Action
A. Jacob, S. Budhiraja, R. Reichel
199927 citations
Semantic Scholar
CD11b is protective in complement-mediated immune complex glomerulonephritis
J. Alexander, L. Chaves, A. Chang, A. Jacob +2 more
2015Kidney International26 citations Open access
Semantic Scholar
Transcriptional regulation of dentin matrix protein 1 (DMP1) in odontoblasts and osteoblasts
A. Jacob, You-Bin Zhang, A. George
2014Connective Tissue Research22 citations
Semantic Scholar
Delayed activation of HNF-3 beta upon retinoic acid-induced teratocarcinoma cell differentiation.
R. Reichel, S. Budhiraja, A. Jacob
1994Experimental Cell Research20 citations
Semantic Scholar
Retinoic acid-mediated activation of HNF-3 alpha during EC stem cell differentiation.
A. Jacob, S. Budhiraja, X. Qian, D. Clevidence +2 more
1994Nucleic Acids Research20 citations
Semantic Scholar
Prominent renal expression of a murine leukemia retrovirus in experimental systemic lupus erythematosus.
J. Alexander, A. Saxena, Li-Hua Bao, A. Jacob +2 more
2002Journal of the American Society of Nephrology17 citations Open access
Semantic Scholar
Immunomodulatory Role of Complement Proteins in the Neuropathology Associated with Opiate Abuse and HIV-1 Co-Morbidity
S. Mahajan, R. Aalinkeel, Neil U. Parikh, A. Jacob +7 more
2017Immunological Investigations12 citations
Semantic Scholar
The HNF-3alpha transcription factor is a primary target for retinoic acid action.
A. Jacob, S. Budhiraja, R. Reichel
1999Experimental Cell Research11 citations
Semantic Scholar
Abnormal Immune Complex Processing and Spontaneous Glomerulonephritis in Complement Factor H-Deficient Mice with Human Complement Receptor 1 on Erythrocytes
J. Alexander, B. Hack, A. Jacob, A. Chang +3 more
2010Journal of Immunology10 citations
Semantic Scholar
Absence of complement factor H alters bone architecture and dynamics.
J. Alexander, Jeyantt S Sankaran, K. Seldeen, R. Thiyagarajan +4 more
2018Immunobiology9 citations
Semantic Scholar
Alteration in kidney glucose and amino acids are implicated in renal pathology in MRL/lpr mice.
J. Alexander, C. Zwingmann, A. Jacob, R. Quigg
2007Biochimica et Biophysica Acta8 citations Open access
Semantic Scholar
Abrogation of immune complex glomerulonephritis by native carboxypeptidase and pharmacological antagonism of the C5a receptor
J. Alexander, L. Chaves, A. Chang, S. Dighe +2 more
2015Cellular & Molecular Immunology7 citations Open access
Semantic Scholar
Absence of complement factor H reduces physical performance in C57BL6 mice
K. Seldeen, R. Thiyagarajan, Yonas Z. Redae, A. Jacob +3 more
2020Immunobiology5 citations Open access
Semantic Scholar
Macrophage Depletion Reduces Disease Pathology in Factor H-Dependent Immune Complex-Mediated Glomerulonephritis
A. Jacob, M. Phelps, Shane Fraher, Marcos Lopez +3 more
2022Journal of Immunological Research4 citations Open access
Semantic Scholar
Effect of lymphotoxin blockage on different stages of Sjogren's syndrome in an animal model
A. Jacob, Long Shen, Jing He, Kelly A. Nealon +2 more
2022Rheumatology & Autoimmunity3 citations Open access
Semantic Scholar
Exercise alleviates symptoms of CNS lupus.
A. Jacob, Lauren Nina Peralta, Deja Pegeus, Kazuki Okamura +3 more
2021Brain Research2 citations
Semantic Scholar
Effects of conventional immunosuppressive therapy on functional and pathological features of CNS lupus in NZB/W mice
J. Alexander, A. Jacob, R. Quigg
20152 citations Open access
Semantic Scholar
Metabolic changes in the evolution of Sjogren′s syndrome in a mouse model.
J. Ambrus, A. Jacob, G. Weisman, Jing-Cai He
20181 citations
Semantic Scholar
204 Novel functions of complement factor H in macrophages
Shane Fraher, A. Jacob, Kathyrn Hausknecht, Roh-Yu Shen +2 more
2023Immunobiology0 citations Open access
Semantic Scholar
Complement Factor H regulates kidney function by modulating macrophages
J. Alexander, Kazuki Okamura, A. Jacob, L. Chaves
2021Journal of Immunology0 citations
Semantic Scholar
Macrophage depletion reduces disease pathology in factor H dependent immune complex glomerulonephritis
A. Jacob, J. Reynolds, A. Chang, R. Quigg +1 more
2018Molecular Immunology0 citations
Semantic Scholar
Complement factor H: Its role in glomerular filtration barrier
S. Mahajan, A. Jacob, R. Aalinkeel, R. Quigg +1 more
2018Molecular Immunology0 citations
Semantic Scholar
Symposium S5: The Role of Complement in the Brain: The Good and the Bad
W. Fodor, F. Cicchetti, O. Isacson, J. Alexander +4 more
20040 citations
Semantic Scholar
systems to study DNA-protein reposition mechanisms
A. Jacob
19850 citations
Semantic Scholar

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