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A. Mupo · SciRah

Researcher profile · Semantic Scholar

A. Mupo

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A. Mupo — researcher profile on SciRah

h-index: 18
Works: 37
Citations: 2,643

Most-cited papers

A CRISPR Dropout Screen Identifies Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia
K. Tzelepis, Hiroko Koike-Yusa, E. De Braekeleer, Yi-Long Li +23 more
2016Cell Reports630 citations Open access
Semantic Scholar
ArrayExpress update—trends in database growth and links to data analysis tools
Gabriella Rustici, N. Kolesnikov, Marco Brandizi, Tony Burdett +22 more
2012Nucleic Acids Res.388 citations Open access
Semantic Scholar
Tbx1 haploinsufficiency is linked to behavioral disorders in mice and humans: Implications for 22q11 deletion syndrome
R. Paylor, B. Glaser, A. Mupo, P. Ataliotis +13 more
2006Proceedings of the National Academy of Sciences of the United States of America329 citations
Semantic Scholar
Targeting Chromatin Regulators Inhibits Leukemogenic Gene Expression in NPM1 Mutant Leukemia
Michael W. M. Kühn, Evelyn J. Song, Zhao-Hui Feng, A. Sinha +12 more
2016Cancer Discovery239 citations Open access
Semantic Scholar
Hemopoietic-specific Sf3b1-K700E knock-in mice display the splicing defect seen in human MDS but develop anemia without ring sideroblasts
A. Mupo, M. Seiler, V. Sathiaseelan, A. Pance +14 more
2016Leukemia125 citations Open access
Semantic Scholar
Synergistic Targeting of FLT3 Mutations in AML via Combined Menin-MLL and FLT3 Inhibition.
Margarita M. Dzama, Marlene Steiner, J. Rausch, D. Sasca +13 more
2020Blood116 citations Open access
Semantic Scholar
A powerful molecular synergy between mutant Nucleophosmin and Flt3-ITD drives acute myeloid leukemia in mice
A. Mupo, L. Celani, O. Dovey, J. Cooper +6 more
2013Leukemia95 citations Open access
Semantic Scholar
Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.
O. Dovey, J. Cooper, A. Mupo, C. Grove +14 more
2017Blood88 citations Open access
Semantic Scholar
Tbx1 regulates Vegfr3 and is required for lymphatic vessel development
Li Chen, A. Mupo, T. Huynh, S. Cioffi +6 more
2010Journal of Cell Biology86 citations Open access
Semantic Scholar
Exploring death receptor pathways as selective targets in cancer therapy.
M. Russo, A. Mupo, C. Spagnuolo, G. Russo
2010Biochemical Pharmacology76 citations
Semantic Scholar
Flavonoid quercetin sensitizes a CD95-resistant cell line to apoptosis by activating protein kinase Cα
M. Russo, R. Palumbo, A. Mupo, M. Tosto +5 more
2003Oncogene69 citations Open access
Semantic Scholar
Genetic modification of primary human B cells to model high-grade lymphoma
Rebecca Caeser, Miriam Di Re, Joanna A. Krupka, Jie Gao +15 more
2019Nature Communications67 citations Open access
Semantic Scholar
Mitochondrial metabolism sustains DNMT3A-R882-mutant clonal haematopoiesis
M. Gozdecka, Monika Dudek, S. Wen, M. Gu +38 more
2025Nature51 citations Open access
Semantic Scholar
Fgf8 expression in the Tbx1 domain causes skeletal abnormalities and modifies the aortic arch but not the outflow tract phenotype of Tbx1 mutants.
F. Vitelli, Zhen Zhang, T. Huynh, Angela Sobotka +2 more
2006Developmental Biology51 citations Open access
Semantic Scholar
Quercetin induced apoptosis in association with death receptors and fludarabine in cells isolated from chronic lymphocytic leukaemia patients
M. Russo, C. Spagnuolo, S. Volpe, A. Mupo +2 more
2010British Journal of Cancer50 citations Open access
Semantic Scholar
Mouse models of NPM1-mutated acute myeloid leukemia: biological and clinical implications
P. Sportoletti, Emanuela Varasano, Roberta Rossi, A. Mupo +4 more
2014Leukemia46 citations Open access
Semantic Scholar
Vitamin D Receptor Controls Cell Stemness in Acute Myeloid Leukemia and in Normal Bone Marrow.
E. Paubelle, Florence Zylbersztejn, T. Maciel, C. Carvalho +22 more
2020Cell Reports43 citations Open access
Semantic Scholar
A CRISPR Dropout Screen Identiﬁes Genetic Vulnerabilities and Therapeutic Targets in Acute Myeloid Leukemia
K. Tzelepis, Hiroko Koike-Yusa, E. De Braekeleer, Yi-Long Li +23 more
29 citations
Semantic Scholar
Imprinting fidelity in mouse iPSCs depends on sex of donor cell and medium formulation
M. Arez, M. Eckersley-Maslin, Tajda Klobučar, João von Gilsa Lopes +8 more
2022Nature Communications16 citations Open access
Semantic Scholar
Mutational synergy during leukemia induction remodels chromatin accessibility, modification and 3-Dimensional DNA topology to alter gene expression
Hai-Yang Yun, N. Narayan, S. Vohra, G. Giotopoulos +18 more
2021Nature Genetics14 citations Open access
Semantic Scholar
Biochemical and Functional Characterization of Protein Kinase CK2 in Ascidian Ciona intestinalis Oocytes at Fertilization
G. Russo, M. Tosto, A. Mupo, Immacolata Castellano +2 more
2004Journal of Biological Chemistry12 citations Open access
Semantic Scholar
Analysis of T cell receptor clonotypes in tumor microenvironment identifies shared cancer-type-specific signatures
Y. Teng, Sheng-Qu-Ah Hong, L. Suteja, João M. L. Dias +7 more
2021Cancer Immunology and Immunotherapy11 citations Open access
Semantic Scholar
Identification of a germline F692L drug resistance variant in cis with Flt3-internal tandem duplication in knock-in mice
O. Dovey, Bin Chen, A. Mupo, Mathias J. Friedrich +6 more
2016Haematologica6 citations Open access
Semantic Scholar
Npm1 haploinsufficiency in collaboration with MEIS1 is sufficient to induce AML in mice
Andrew Muranyi, Tobias Ammer, A. Kechter, Vijay P. S. Rawat +9 more
2022Blood Advances5 citations Open access
Semantic Scholar
Sf3b1 K700E Mutation Impairs Pre-mRNA Splicing and Definitive Hematopoiesis in a Conditional Knock-in Mouse Model
A. Mupo, Vijitha Sathiaseelan, M. Seiler, D. Kent +12 more
20154 citations Open access
Semantic Scholar
Mutational synergy coordinately remodels chromatin accessibility, enhancer landscape and 3-Dimensional DNA topology to alter gene expression during leukemia induction
Hai-Yang Yun, S. Vohra, A. Mupo, G. Giotopoulos +15 more
2019bioRxiv2 citations Open access
Semantic Scholar
Genetic modification of primary human B cells generates translationally-relevant models of high-grade lymphoma
Rebecca Caeser, Miriam Di Re, Joanna A. Krupka, Jie Gao +15 more
2019bioRxiv1 citations Open access
Semantic Scholar
Combined Targeting of the Menin-MLL1 Chromatin Complex and FLT3 As a Novel Therapeutic Concept Against NPM1 Mutant or MLL-Rearranged AML with Mutated FLT3
Margarita M. Dzama, Martha C. Taubert, Kerstin Kunz, J. Rausch +9 more
2019Blood1 citations Open access
Semantic Scholar
A Crispr/Cas9 Drop-out Screen Identifies Genome-Wide Genetic Valnerubilities in Acute Myeloid Leukaemia
K. Tzelepis, Hiroko Koike-Yusa, E. De Braekeleer, Yi-Long Li +17 more
20151 citations
Semantic Scholar
Correction to: Analysis of T cell receptor clonotypes in tumor microenvironment identifies shared cancer-type-specific signatures
Y. Teng, Sheng-Qu-Ah Hong, L. Suteja, João M. L. Dias +7 more
2021Cancer Immunology and Immunotherapy0 citations Open access
Semantic Scholar
Abstract 3841: Therapeutic targeting ofFLT3mutations in AML via menin-MLL1 and FLT3 inhibition
Margarita M. Dzama, Martha C. Taubert, Kerstin Kunz, J. Rausch +8 more
2019Experimental and Molecular Therapeutics0 citations
Semantic Scholar
Dovey et al MOLECULAR SYNERGY IN NPM1 MUTANT AML Molecular synergy underlies the co-occurrence paterns and phenotype of NPM1-mutant acute myeloid leukemia
O. Dovey, J. Cooper, A. Mupo, C. Grove +12 more
20180 citations
Semantic Scholar
Molecular synergy underlies the co-occurrence patterns and phenotype of NPM 1-mutant 1 acute myeloid leukemia . 2 3
O. Dovey, J. Cooper, A. Mupo, C. Grove +14 more
20170 citations
Semantic Scholar
MYELOID NEOPLASIA Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1 -mutant acute myeloid leukemia
O. Dovey, J. Cooper, A. Mupo, C. Grove +14 more
20170 citations
Semantic Scholar
Identification of a germline F 692 L drug resistance variant in cis with Flt 3-ITD in knockin mice by
O. Dovey, Bin Chen, A. Mupo, Mathias J. Friedrich +7 more
20160 citations
Semantic Scholar
Initial analysis of the phenotypic consequences of SF3B1 K700E mutation expression in vitro and in vivo
V. Sathiaseelan, A. Mupo, A. Pance, Suruchi Pacharne +6 more
20150 citations
Semantic Scholar
394 Quercetin enforces death receptor-ligands induced apoptosis in chronic lymphocytic leukemia
A. Mupo, M. Russo, C. Spagnuolo, S. Volpe +1 more
20100 citations
Semantic Scholar

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