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A. Lackner · SciRah

Researcher profile · Semantic Scholar

A. Lackner

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A. Lackner — researcher profile on SciRah

h-index: 73
Works: 249
Citations: 24K

Most-cited papers

Anti-spike IgG causes severe acute lung injury by skewing macrophage responses during acute SARS-CoV infection.
Li Liu, Q. Wei, Qing-Qing Lin, Jun Fang +15 more
2019JCI Insight829 citations Open access
Semantic Scholar
Epithelial Cells Lining Salivary Gland Ducts Are Early Target Cells of Severe Acute Respiratory Syndrome Coronavirus Infection in the Upper Respiratory Tracts of Rhesus Macaques
Li Liu, Q. Wei, X. Alvarez, Hai-Bo Wang +9 more
2011Journal of Virology404 citations Open access
Semantic Scholar
Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis
D. Kaushal, Taylor W. Foreman, U. Gautam, X. Alvarez +15 more
2015Nature Communications216 citations Open access
Semantic Scholar
Monocyte/macrophages and their role in HIV neuropathogenesis
T. Burdo, A. Lackner, Kenneth C. Williams
2013Immunological Reviews216 citations Open access
Semantic Scholar
Genetic Requirements for the Survival of Tubercle Bacilli in Primates
N. K. Dutta, S. Mehra, P. Didier, C. Roy +9 more
2010Journal of Infectious Diseases167 citations Open access
Semantic Scholar
The DosR Regulon Modulates Adaptive Immunity and Is Essential for Mycobacterium tuberculosis Persistence.
S. Mehra, Taylor W. Foreman, P. Didier, Muhammad H. Ahsan +15 more
2015American Journal of Respiratory and Critical Care Medicine159 citations Open access
Semantic Scholar
The level of monocyte turnover predicts disease progression in the macaque model of AIDS.
A. Hasegawa, Huining Liu, B. Ling, J. Borda +9 more
2009Blood155 citations Open access
Semantic Scholar
The non-human primate model of tuberculosis
D. Kaushal, S. Mehra, P. Didier, A. Lackner
2012Journal of medical primatology154 citations Open access
Semantic Scholar
Engineering HIV-Resistant Human CD4+ T Cells with CXCR4-Specific Zinc-Finger Nucleases
Craig B. Wilen, Jianbin Wang, J. Tilton, Jeffrey C. Miller +19 more
2011PLoS Pathogens147 citations Open access
Semantic Scholar
Recently infiltrating MAC387(+) monocytes/macrophages a third macrophage population involved in SIV and HIV encephalitic lesion formation.
C. Soulas, Cecily N. Conerly, Woong-Ki Kim, T. Burdo +3 more
2011American Journal of Pathology130 citations Open access
Semantic Scholar
CD4+ T-cell–independent mechanisms suppress reactivation of latent tuberculosis in a macaque model of HIV coinfection
Taylor W. Foreman, S. Mehra, D. LoBato, Adel Malek +14 more
2016Proceedings of the National Academy of Sciences of the United States of America121 citations Open access
Semantic Scholar
CD4 Depletion in SIV-Infected Macaques Results in Macrophage and Microglia Infection with Rapid Turnover of Infected Cells
Luca Micci, X. Alvarez, R. Iriele, A. Ortiz +15 more
2014PLoS Pathogens120 citations Open access
Semantic Scholar
IL-17-producing innate lymphoid cells are restricted to mucosal tissues and are depleted in SIV-infected macaques
Huan-Bin Xu, Xiao-Lei Wang, D. X. Liu, Terri Moroney-Rasmussen +2 more
2012Mucosal Immunology114 citations Open access
Semantic Scholar
HIV Pathogenesis: The Host
A. Lackner, M. Lederman, B. Rodriguez
2012Cold Spring Harbor Perspectives in Medicine112 citations Open access
Semantic Scholar
Reactivation of latent tuberculosis in rhesus macaques by co-infection with Simian Immunodeficiency Virus
S. Mehra, Nadia A. Golden, N. K. Dutta, C. Midkiff +11 more
2011Journal of medical primatology110 citations Open access
Semantic Scholar
Granuloma correlates of protection against tuberculosis and mechanisms of immune modulation by Mycobacterium tuberculosis.
S. Mehra, X. Alvarez, P. Didier, Lara A. Doyle +3 more
2013Journal of Infectious Diseases103 citations Open access
Semantic Scholar
TLR7/8 adjuvant overcomes newborn hyporesponsiveness to pneumococcal conjugate vaccine at birth.
David J. Dowling, S. V. van Haren, A. Scheid, Ilana Bergelson +18 more
2017JCI Insight100 citations Open access
Semantic Scholar
Aerosol Vaccination with AERAS-402 Elicits Robust Cellular Immune Responses in the Lungs of Rhesus Macaques but Fails to Protect Against High-Dose Mycobacterium tuberculosis Challenge
P. Darrah, D. Bolton, A. Lackner, D. Kaushal +12 more
2014Journal of Immunology93 citations Open access
Semantic Scholar
The Mycobacterium tuberculosis stress response factor SigH is required for bacterial burden as well as immunopathology in primate lungs.
S. Mehra, Nadia A. Golden, Kerstan J Stuckey, P. Didier +11 more
2012Journal of Infectious Diseases79 citations Open access
Semantic Scholar
Contributions of Nonhuman Primates to Research on Aging
Elizabeth S. Didier, Andrew G. MacLean, M. Mohan, P. Didier +2 more
2016Veterinary Pathology-Supplement77 citations Open access
Semantic Scholar
Fetal demise and failed antibody therapy during Zika virus infection of pregnant macaques
D. Magnani, T. Rogers, N. Maness, N. Grubaugh +28 more
2018Nature Communications74 citations Open access
Semantic Scholar
Differentiation kinetics of blood monocytes and dendritic cells in macaques: insights to understanding human myeloid cell development
C. Sugimoto, A. Hasegawa, Yohei Saito, Y. Fukuyo +9 more
2015Journal of Immunology69 citations Open access
Semantic Scholar
The Stress-Response Factor SigH Modulates the Interaction between Mycobacterium tuberculosis and Host Phagocytes
N. K. Dutta, S. Mehra, A. Martínez, X. Alvarez +6 more
2012PLoS ONE65 citations Open access
Semantic Scholar
Persistent Simian Immunodeficiency Virus Infection Drives Differentiation, Aberrant Accumulation, and Latent Infection of Germinal Center Follicular T Helper Cells
Huan-Bin Xu, Xiao-Lei Wang, Naomi Malam, P. Aye +3 more
2015Journal of Virology60 citations Open access
Semantic Scholar
Innate immune activation in the pathogenesis of a murine model of globoid cell leukodystrophy.
E. Snook, Jeanne M. Fisher-Perkins, Hope A. Sansing, Kim M. Lee +5 more
2014American Journal of Pathology52 citations Open access
Semantic Scholar
PD-1HIGH Follicular CD4 T Helper Cell Subsets Residing in Lymph Node Germinal Centers Correlate with B Cell Maturation and IgG Production in Rhesus Macaques
Huan-Bin Xu, Xiao-Lei Wang, A. Lackner, R. Veazey
2014Frontiers in Immunology50 citations Open access
Semantic Scholar
Hypoxia Sensing and Persistence Genes Are Expressed during the Intragranulomatous Survival of Mycobacterium tuberculosis
Teresa A. Hudock, Taylor W. Foreman, N. Bandyopadhyay, U. Gautam +13 more
2017American Journal of Respiratory Cell and Molecular Biology49 citations Open access
Semantic Scholar
Increased B7-H1 expression on dendritic cells correlates with PD-1 expression on T cells in SIV-infected macaques and may contribute to T cell dysfunction and disease progression
Huan-Bin Xu, Xiao-Lei Wang, B. Pahar, Terri Moroney-Rasmussen +3 more
2010Journal of Immunology48 citations Open access
Semantic Scholar
The Large Intestine As A Major Reservoir For SIV In Long-Term Non-Progressing Macaques
B. Ling, M. Mohan, A. Lackner, L. C. Green +3 more
2010Journal of Infectious Diseases47 citations Open access
Semantic Scholar
Translational Research in the Nonhuman Primate Model of Tuberculosis.
Taylor W. Foreman, S. Mehra, A. Lackner, D. Kaushal
2017ILAR journal45 citations Open access
Semantic Scholar
Type 3 innate lymphoid cell depletion is mediated by TLRs in lymphoid tissues of simian immunodeficiency virus‐infected macaques
Huan-Bin Xu, Xiao-Lei Wang, A. Lackner, R. Veazey
2015The FASEB Journal44 citations Open access
Semantic Scholar
Increased monocyte turnover is associated with interstitial macrophage accumulation and pulmonary tissue damage in SIV‐infected rhesus macaques
Yanhui Cai, C. Sugimoto, D. X. Liu, Cecily C. Midkiff +5 more
2015Journal of Leukocyte Biology43 citations Open access
Semantic Scholar
In vivo proton magnetic resonance spectroscopy reveals region specific metabolic responses to SIV infection in the macaque brain
E. Ratai, S. Pilkenton, J. B. Greco, M. Lentz +9 more
2009BMC Neuroscience43 citations Open access
Semantic Scholar
Spatiotemporal Interplay of Severe Acute Respiratory Syndrome Coronavirus and Respiratory Mucosal Cells Drives Viral Dissemination in Rhesus Macaques
Li Liu, Q. Wei, K. Nishiura, Jie Peng +6 more
2015Mucosal Immunology42 citations Open access
Semantic Scholar
Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic SIV infection of rhesus macaques
Mahesh Mohan, Vinay Kumar, A. Lackner, X. Alvarez
2014Journal of Immunology39 citations Open access
Semantic Scholar
The Role of Defensins in HIV Pathogenesis
Barcley T Pace, A. Lackner, E. Porter, B. Pahar
2017Mediators of Inflammation38 citations Open access
Semantic Scholar
MCP-3/CCL7 production by astrocytes: Implications for SIV neuroinvasion and AIDS encephalitis
Nicole A. Renner, N. S. Ivey, R. Redmann, A. Lackner +1 more
2011Journal of Neurovirology38 citations Open access
Semantic Scholar
Persistent SIV infection causes ultimate depletion of follicular T helper cells in AIDS
Huan-Bin Xu, Xiao-Lei Wang, Naomi Malam, A. Lackner +1 more
2015Journal of Immunology37 citations Open access
Semantic Scholar
Loss of a Tyrosine-Dependent Trafficking Motif in the Simian Immunodeficiency Virus Envelope Cytoplasmic Tail Spares Mucosal CD4 Cells but Does Not Prevent Disease Progression
M. Breed, Andrea P. O. Jordan, P. Aye, Cornelis F Lichtveld +14 more
2012Journal of Virology37 citations Open access
Semantic Scholar
CD8 down‐regulation and functional impairment of SIV‐specific cytotoxic T lymphocytes in lymphoid and mucosal tissues during SIV infection
Huan-Bin Xu, Xiao-Lei Wang, A. Lackner, R. Veazey
2013Journal of Leukocyte Biology35 citations Open access
Semantic Scholar
Simian immunodeficiency virus selectively infects proliferating CD4+ T cells in neonatal rhesus macaques.
Xiao-Lei Wang, Huan-Bin Xu, B. Pahar, X. Alvarez +5 more
2010Blood35 citations Open access
Semantic Scholar
Nonhuman Primate Models and Understanding the Pathogenesis of HIV Infection and AIDS.
R. Veazey, A. Lackner
2017ILAR journal32 citations Open access
Semantic Scholar
Comparison of the vaginal environment of Macaca mulatta and Macaca nemestrina throughout the menstrual cycle
Sarah V. Hadzic, Xiao-Lei Wang, Jason P. Dufour, Lara A. Doyle +4 more
2014American Journal of Reproductive Immunology31 citations Open access
Semantic Scholar
Neurovirulence and Immunogenicity of Attenuated Recombinant Vesicular Stomatitis Viruses in Nonhuman Primates
D. Clarke, Farooq Nasar, S. Chong, J. Johnson +20 more
2014Journal of Virology31 citations Open access
Semantic Scholar
Lack of Interleukin-10-Mediated Anti-Inflammatory Signals and Upregulated Interferon Gamma Production Are Linked to Increased Intestinal Epithelial Cell Apoptosis in Pathogenic Simian Immunodeficiency Virus Infection
D. Pan, C. Kenway-Lynch, Wendy Lala, R. Veazey +3 more
2014Journal of Virology30 citations Open access
Semantic Scholar
Molecular Pathogenesis of Genetic and Inherited Diseases Clinical and Immunopathologic Alterations in Rhesus Macaques Affected with Globoid Cell Leukodystrophy
J. Borda, X. Alvarez, M. Mohan, M. Ratterree +3 more
201030 citations
Semantic Scholar
Preferential destruction of interstitial macrophages over alveolar macrophages as a cause of pulmonary disease in SIV-infected rhesus macaques
Yanhui Cai, C. Sugimoto, M. Araínga, C. Midkiff +6 more
2015Journal of Immunology29 citations Open access
Semantic Scholar
Non-human primate models of SIV infection and CNS neuropathology
K. Williams, A. Lackner, J. Mallard
2016Current Opinion in Virology28 citations Open access
Semantic Scholar
Cytokine/Chemokine Responses in Activated CD4+ and CD8+ T Cells Isolated from Peripheral Blood, Bone Marrow, and Axillary Lymph Nodes during Acute Simian Immunodeficiency Virus Infection
C. Kenway-Lynch, Arpita Das, A. Lackner, B. Pahar
2014Journal of Virology28 citations Open access
Semantic Scholar
Focused Examination of the Intestinal lamina Propria Yields Greater Molecular Insight into Mechanisms Underlying SIV Induced Immune Dysfunction
M. Mohan, D. Kaushal, P. Aye, X. Alvarez +2 more
2012PLoS ONE26 citations Open access
Semantic Scholar

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