Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

J. C. Perales · SciRah

Researcher profile · Semantic Scholar

J. C. Perales

Share profile

J. C. Perales — researcher profile on SciRah

h-index: 29
Works: 72
Citations: 4,786

Most-cited papers

Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
Ping-Chih Ho, J. Bihuniak, Andrew N. Macintyre, Matthew M. Staron +14 more
2015Cell1,349 citations Open access
Semantic Scholar
Elevated TCA cycle function in the pathology of diet-induced hepatic insulin resistance and fatty liver[S]
S. Satapati, N. Sunny, B. Kucejova, Xiao-Rong Fu +6 more
2012Journal of Lipid Research376 citations Open access
Semantic Scholar
Gene transfer in vivo: sustained expression and regulation of genes introduced into the liver by receptor-targeted uptake.
J. C. Perales, T. Ferkol, H. Beegen, O. Ratnoff +1 more
1994Proceedings of the National Academy of Sciences of the United States of America292 citations Open access
Semantic Scholar
6-Phosphofructo-2-kinase (pfkfb3) Gene Promoter Contains Hypoxia-inducible Factor-1 Binding Sites Necessary for Transactivation in Response to Hypoxia*
M. Obach, Àurea Navarro-Sabaté, J. Caro, Xianguo Kong +6 more
2004Journal of Biological Chemistry254 citations Open access
Semantic Scholar
Mitochondrial Phosphoenolpyruvate Carboxykinase (PEPCK-M) Is a Pro-survival, Endoplasmic Reticulum (ER) Stress Response Gene Involved in Tumor Cell Adaptation to Nutrient Availability*
Andrés Méndez-Lucas, P. Hyroššová, L. Novellasdemunt, F. Viñals +1 more
2014Journal of Biological Chemistry174 citations Open access
Semantic Scholar
Receptor-mediated gene transfer into macrophages.
T. Ferkol, J. C. Perales, F. Mularo, R. Hanson
1996Proceedings of the National Academy of Sciences of the United States of America174 citations Open access
Semantic Scholar
Biological Properties of Poly-l-lysine-DNA Complexes Generated by Cooperative Binding of the Polycation* 210
Ge Liu, Maria Molas, Gregory A. Grossmann, Murali K. Pasumarthy +3 more
2001Journal of Biological Chemistry155 citations Open access
Semantic Scholar
Gene transfer into the airway epithelium of animals by targeting the polymeric immunoglobulin receptor.
T. Ferkol, J. C. Perales, Elizabeth Eckman, C. Kaetzel +2 more
1995Journal of Clinical Investigation149 citations Open access
Semantic Scholar
Intestinal Inflammation Modulates the Epithelial Response to Butyrate in Patients With Inflammatory Bowel Disease
Elena Ferrer-Picón, I. Dotti, A. Corraliza, A. Mayorgas +8 more
2019Inflammatory Bowel Diseases125 citations Open access
Semantic Scholar
Pck1 Gene Silencing in the Liver Improves Glycemia Control, Insulin Sensitivity, and Dyslipidemia in db/db Mice
Alicia G. Gómez-Valadés, Andrés Méndez-Lucas, Anna Vidal-Alabró, F. X. Blasco +4 more
2008Diabetes125 citations Open access
Semantic Scholar
Selective siRNA-mediated suppression of 5-HT1A autoreceptors evokes strong anti-depressant-like effects
A. Bortolozzi, A. Castañé, Jana Semaková, Noemí Santana +9 more
2012Molecular Psychiatry124 citations Open access
Semantic Scholar
Biochemical and Functional Characterization of DNA Complexes Capable of Targeting Genes to Hepatocytes via the Asialoglycoprotein Receptor*
J. C. Perales, Gregory A. Grossmann, Maria Molas, Ge Liu +4 more
1997Journal of Biological Chemistry118 citations Open access
Semantic Scholar
A DERL3-associated defect in the degradation of SLC2A1 mediates the Warburg effect
Paula Lopez-Serra, M. Marcilla, A. Villanueva, A. Ramos-Fernández +24 more
2014Nature Communications115 citations Open access
Semantic Scholar
PEPCK-M expression in mouse liver potentiates, not replaces, PEPCK-C mediated gluconeogenesis
Andrés Méndez-Lucas, J. Duarte, N. Sunny, S. Satapati +5 more
2013Journal of Hepatology104 citations Open access
Semantic Scholar
Overcoming diabetes-induced hyperglycemia through inhibition of hepatic phosphoenolpyruvate carboxykinase (GTP) with RNAi.
Alicia G. Gómez-Valadés, Anna Vidal-Alabró, Maria Molas, J. Boada +3 more
2006Molecular Therapy85 citations Open access
Semantic Scholar
Akt-dependent Activation of the Heart 6-Phosphofructo-2-kinase/Fructose-2,6-bisphosphatase (PFKFB2) Isoenzyme by Amino Acids*
L. Novellasdemunt, Irantzu Tato, Àurea Navarro-Sabaté, M. Ruiz-Meana +6 more
2013Journal of Biological Chemistry77 citations Open access
Semantic Scholar
Role of the Transforming Growth Factor-β in regulating hepatocellular carcinoma oxidative metabolism
J. Soukupová, A. Malfettone, P. Hyroššová, M. Hernández-Alvarez +9 more
2017Scientific Reports67 citations Open access
Semantic Scholar
Tumors defective in homologous recombination rely on oxidative metabolism: relevance to treatments with PARP inhibitors
Álvaro Lahiguera, P. Hyroššová, A. Figueras, Diana Garzón +21 more
2020EMBO Molecular Medicine61 citations Open access
Semantic Scholar
The combination of ischemic preconditioning and liver Bcl-2 overexpression is a suitable strategy to prevent liver and lung damage after hepatic ischemia-reperfusion.
C. Peralta, J. C. Perales, R. Bartrons, C. Mitchell +7 more
2002American Journal of Pathology48 citations Open access
Semantic Scholar
Insulin induces PFKFB3 gene expression in HT29 human colon adenocarcinoma cells.
Lluı́s Riera, A. Manzano, Àurea Navarro-Sabaté, J. C. Perales +1 more
2002Biochimica et Biophysica Acta46 citations Open access
Semantic Scholar
Triheptanoin supplementation to ketogenic diet curbs cognitive impairment in APP/PS1 mice used as a model of familial Alzheimer's disease.
E. Aso, Jana Semaková, L. Joda, V. Semak +5 more
2013Current Alzheimer Research45 citations
Semantic Scholar
A Transcriptome-proteome Integrated Network Identifies Endoplasmic Reticulum thiol oxidoreductase (ERp57) as a Hub that Mediates Bone Metastasis*
Naiara Santana-Codina, R. Carretero, R. Sanz-Pamplona, T. Cabrera +8 more
2013Molecular & Cellular Proteomics39 citations Open access
Semantic Scholar
The effect of the composition of PLA films and lactate release on glial and neuronal maturation and the maintenance of the neuronal progenitor niche.
Z. Álvarez, M. Mateos-Timoneda, P. Hyroššová, Ó. Castaño +4 more
2013Biomaterials39 citations Open access
Semantic Scholar
Fructose 1,6-bisphosphate prevented endotoxemia, macrophage activation, and liver injury induced by D-galactosamine in rats*
E. Cuesta, J. Boada, Roser Calafell, J. C. Perales +2 more
2006Critical Care Medicine39 citations
Semantic Scholar
Neuronal Progenitor Maintenance Requires Lactate Metabolism and PEPCK-M-Directed Cataplerosis.
Z. Álvarez, P. Hyroššová, J. C. Perales, S. Alcántara
2016Cerebral Cortex38 citations
Semantic Scholar
Cholesteryl ester transfer activity in liver disease and cholestasis, and its relation with fatty acid composition of lipoprotein lipids.
Angel Iglesias, M. Arránz, J. J. Álvarez, J. C. Perales +3 more
1996Clinica chimica acta; international journal of clinical chemistry37 citations Open access
Semantic Scholar
Remission of obesity and insulin resistance is not sufficient to restore mitochondrial homeostasis in visceral adipose tissue
A. Gonzalez-Franquesa, Pau Gama-Pérez, M. Kulis, Karolina Szczepanowska +43 more
2022Redox Biology32 citations Open access
Semantic Scholar
Assessment of a dual regulatory role for NO in liver regeneration after partial hepatectomy: protection against apoptosis and retardation of hepatocyte proliferation
Miriam Zeini, S. Hortelano, P. Través, Alicia G. Gómez-Valadés +4 more
2005The FASEB Journal32 citations Open access
Semantic Scholar
Functionally enhanced siRNA targeting TNFα attenuates DSS-induced colitis and TLR-mediated immunostimulation in mice.
Sandra M. Ocampo, C. Romero, A. Aviñó, Juan F Burgueño +5 more
2012Molecular Therapy30 citations Open access
Semantic Scholar
Phosphoenolpyruvate from Glycolysis and PEPCK Regulate Cancer Cell Fate by Altering Cytosolic Ca2+
Juan Moreno-Felici, P. Hyroššová, M. Aragó, Sergio Rodríguez-Arévalo +3 more
2019Cells29 citations Open access
Semantic Scholar
Synthesis and in vitro inhibition properties of siRNA conjugates carrying glucose and galactose with different presentations
A. Aviñó, Sandra M. Ocampo, Ricardo Lucas, J. Reina +3 more
2011Molecular diversity28 citations Open access
Semantic Scholar
Effect of North Bicyclo[3.1.0]hexane 2′‐Deoxy‐pseudosugars on RNA Interference: A Novel Class of siRNA Modification
M. Terrazas, Sandra M. Ocampo, J. C. Perales, V. Márquez +1 more
2011ChemBioChem28 citations
Semantic Scholar
Synthesis of oligonucleotides carrying amino lipid groups at the 3'-end for RNA interference studies.
S. Grijalvo, Sandra M. Ocampo, J. C. Perales, R. Eritja
2010Journal of Organic Chemistry24 citations Open access
Semantic Scholar
Synthesis of Lipid–Oligonucleotide Conjugates for RNA Interference Studies
S. Grijalvo, Sandra M. Ocampo, J. C. Perales, R. Eritja
2011Chemistry and Biodiversity23 citations Open access
Semantic Scholar
Fructose 1,6-bisphosphate reduced TNF-alpha-induced apoptosis in galactosamine sensitized rat hepatocytes through activation of nitric oxide and cGMP production.
Roser Calafell, J. Boada, Antonio F. Santidrián, J. Gil +3 more
2009European Journal of Pharmacology23 citations
Semantic Scholar
Overexpression of ubiquitous 6-phosphofructo-2-kinase in the liver of transgenic mice results in weight gain.
Joan Duran, Àurea Navarro-Sabaté, A. Pujol, J. C. Perales +4 more
2008Biochemical and Biophysical Research Communications - BBRC22 citations
Semantic Scholar
PEPCK-M recoups tumor cell anabolic potential in a PKC-ζ-dependent manner
P. Hyroššová, M. Aragó, Juan Moreno-Felici, Xiarong Fu +6 more
2021Cancer & Metabolism18 citations Open access
Semantic Scholar
Short-Fiber Protein of Ad40 Confers Enteric Tropism and Protection Against Acidic Gastrointestinal Conditions
E. Rodríguez, C. Romero, A. Río, M. Miralles +9 more
2013Human Gene Therapy Methods18 citations
Semantic Scholar
Branched RNA: A New Architecture for RNA Interference
A. Aviñó, Sandra M. Ocampo, J. C. Perales, R. Eritja
2011Journal of Nucleic Acids18 citations Open access
Semantic Scholar
PEPCK-C reexpression in the liver counters neonatal hypoglycemia in Pck1del/del mice, unmasking role in non-gluconeogenic tissues
Jana Semaková, P. Hyroššová, Andrés Méndez-Lucas, E. Cutz +4 more
2016Journal of physiology and biochemistry17 citations
Semantic Scholar
p38α function in osteoblasts influences adipose tissue homeostasis
Edgardo Rodríguez-Carballo, Beatriz Gámez, Andrés Méndez-Lucas, Manuela Sánchez-Freutrie +5 more
2015The FASEB Journal16 citations
Semantic Scholar
Copolymers of poly-L-lysine with serine and tryptophan form stable DNA vectors: implications for receptor-mediated gene transfer.
Alicia G. Gómez-Valadés, Maria Molas, Anna Vidal-Alabró, Jordi Bermúdez +2 more
2005Journal of Controlled Release16 citations
Semantic Scholar
Histamine signaling and metabolism identify potential biomarkers and therapies for lymphangioleiomyomatosis
C. Herranz, F. Mateo, A. Baiges, Gorka Ruiz de Garibay +53 more
2021EMBO Molecular Medicine15 citations Open access
Semantic Scholar
Specific Jak3 Downregulation in Lymphocytes Impairs γc Cytokine Signal Transduction and Alleviates Antigen-driven Inflammation In Vivo
Alicia G. Gómez-Valadés, M. Llamas, Sílvia Blanch, J. C. Perales +3 more
2012Molecular Therapy: Nucleic Acids15 citations Open access
Semantic Scholar
Reduced Milk Triglycerides in Mice Lacking Phosphoenolpyruvate Carboxykinase in Mammary Gland Adipocytes and White Adipose Tissue Contribute to the Development of Insulin Resistance in Pups
Colleen M. Croniger, Chang-Wen Hsieh, Carrie A. Millward, D. Desantis +3 more
2009Journal of NutriLife15 citations Open access
Semantic Scholar
Pharmacology and preclinical validation of a novel anticancer compound targeting PEPCK-M.
M. Aragó, Juan Moreno-Felici, Sònia Abás, Sergio Rodríguez-Arévalo +14 more
2019Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie13 citations Open access
Semantic Scholar
Stepwise synthesis of RNA conjugates carrying peptide sequences for RNA interference studies
A. Aviñó, Sandra M. Ocampo, Clara Caminal, J. C. Perales +1 more
2009Molecular diversity13 citations
Semantic Scholar
Effects of Lifestyle Intervention in Tissue-Specific Lipidomic Profile of Formerly Obese Mice
N. Dahdah, A. Gonzalez-Franquesa, S. Samino, Pau Gama-Pérez +5 more
2021International Journal of Molecular Sciences12 citations Open access
Semantic Scholar
Characterization of a new liver- and kidney-specific pfkfb3 isozyme that is downregulated by cell proliferation and dedifferentiation.
Joan Duran, Marta Gómez, Àurea Navarro-Sabaté, Lluís Riera-Sans +4 more
2008Biochemical and Biophysical Research Communications - BBRC11 citations
Semantic Scholar
Aspirin inhibits NF-kappaB activation in a glycolysis-depleted lung epithelial cell line.
E. Cuesta, J. Boada, J. C. Perales, T. Roig +1 more
2005European Journal of Pharmacology11 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

R. Bartrons×11
Invite
R. Bartrons — researcher profile on SciRah
Andrés Méndez-Lucas×9
Invite
Andrés Méndez-Lucas — researcher profile on SciRah
P. Hyroššová×9
Invite
P. Hyroššová — researcher profile on SciRah
Jordi Bermúdez×9
Invite
Jordi Bermúdez — researcher profile on SciRah

Sandra M. Ocampo

×7

Invite

Sandra M. Ocampo — researcher profile on SciRah

Invite

R. Eritja — researcher profile on SciRah

Invite

F. Viñals — researcher profile on SciRah

Invite

R. Hanson — researcher profile on SciRah

Àurea Navarro-Sabaté×5

Invite

Àurea Navarro-Sabaté — researcher profile on SciRah

Invite

Ó. Yanes — researcher profile on SciRah

P. García-Rovés×5

Invite

P. García-Rovés — researcher profile on SciRah

Shawn C. Burgess×4

Invite

Shawn C. Burgess — researcher profile on SciRah