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Bei Liu · SciRah

Researcher profile · Semantic Scholar

Bei Liu

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Bei Liu — researcher profile on SciRah

h-index: 40
Works: 94
Citations: 4,565

Most-cited papers

Heat shock protein gp96 is a master chaperone for toll-like receptors and is important in the innate function of macrophages.
Yi Yang, Bei Liu, Jie Dai, P. Srivastava +3 more
2007Immunity482 citations Open access
Semantic Scholar
Platelets Subvert T Cell Immunity Against Cancer via GARP-TGFβ Axis
Saleh Rachidi, Alessandra Metelli, Brian P. Riesenberg, Bill X. Wu +10 more
2017Science immunology315 citations Open access
Semantic Scholar
Targeting inflammasome/IL-1 pathways for cancer immunotherapy
Beichu Guo, Shunjun Fu, Jin-Yu Zhang, Bei Liu +1 more
2016Scientific Reports285 citations Open access
Semantic Scholar
Folding of Toll-like receptors by the HSP90 paralogue gp96 requires a substrate-specific cochaperone
Bei Liu, Yi Yang, Zhijuan Qiu, Matthew M. Staron +8 more
2010Nature Communications196 citations Open access
Semantic Scholar
Cell surface expression of an endoplasmic reticulum resident heat shock protein gp96 triggers MyD88-dependent systemic autoimmune diseases
Bei Liu, Jie Dai, Hong Zheng, D. Stoilova +2 more
2003Proceedings of the National Academy of Sciences of the United States of America186 citations Open access
Semantic Scholar
Endoplasmic reticulum HSP90b1 (gp96, grp94) optimizes B-cell function via chaperoning integrin and TLR but not immunoglobulin.
Bei Liu, Zi-Hai Li
2008Blood141 citations Open access
Semantic Scholar
TLR4 Up-Regulation at Protein or Gene Level Is Pathogenic for Lupus-Like Autoimmune Disease1
Bei Liu, Yi Yang, Jie Dai, R. Medzhitov +3 more
2006Journal of Immunology139 citations Open access
Semantic Scholar
gp96, an endoplasmic reticulum master chaperone for integrins and Toll-like receptors, selectively regulates early T and B lymphopoiesis.
Matthew M. Staron, Yi Yang, Bei Liu, Janet Li +5 more
2010Blood131 citations Open access
Semantic Scholar
Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-β
Alessandra Metelli, Bill X. Wu, Brian P. Riesenberg, S. Guglietta +14 more
2020Science Translational Medicine126 citations Open access
Semantic Scholar
Essential roles of grp94 in gut homeostasis via chaperoning canonical Wnt pathway
Bei Liu, Matthew M. Staron, F. Hong, Bill X. Wu +7 more
2013Proceedings of the National Academy of Sciences of the United States of America118 citations Open access
Semantic Scholar
Combination of Imatinib Mesylate with Autologous Leukocyte-Derived Heat Shock Protein and Chronic Myelogenous Leukemia
Zi-Hai Li, Y. Qiao, Bei Liu, Elizabeth J Laska +12 more
2005Clinical Cancer Research106 citations
Semantic Scholar
Phospholipase C beta3 deficiency leads to macrophage hypersensitivity to apoptotic induction and reduction of atherosclerosis in mice.
Zhenglong Wang, Bei Liu, Ping Wang, Xuemei Dong +7 more
2008Journal of Clinical Investigation97 citations Open access
Semantic Scholar
Surface Expression of TGF-β Docking Receptor GARP Promotes Oncogenesis and Immune Tolerance in Breast Cancer
Alessandra Metelli, Bill X. Wu, Caroline W. Fugle, Saleh Rachidi +9 more
2016Cancer Research96 citations Open access
Semantic Scholar
The Molecular Chaperone gp96/GRP94 Interacts with Toll-like Receptors and Integrins via Its C-terminal Hydrophobic Domain*
Shuang Wu, F. Hong, D. Gewirth, Beichu Guo +2 more
2012Journal of Biological Chemistry94 citations Open access
Semantic Scholar
Cell surface expression of heat shock protein gp96 enhances cross-presentation of cellular antigens and the generation of tumor-specific T cell memory.
Jie Dai, Bei Liu, M. Caudill, Hong Zheng +3 more
2003Cancer Immunity88 citations
Semantic Scholar
Clients and Oncogenic Roles of Molecular Chaperone gp96/grp94
Ephraim A. Ansa-Addo, J. Thaxton, F. Hong, Bill X. Wu +9 more
2016Current Topics in Medicinal Chemistry87 citations Open access
Semantic Scholar
GP96 is a GARP chaperone and controls regulatory T cell functions.
Yong-Liang Zhang, Bill X. Wu, Alessandra Metelli, J. Thaxton +8 more
2015Journal of Clinical Investigation83 citations Open access
Semantic Scholar
Vaccination with Human Pluripotent Stem Cells Generates a Broad Spectrum of Immunological and Clinical Responses Against Colon Cancer
Yi Li, Hui Zeng, Ren-He Xu, Bei Liu +1 more
2009Stem Cells78 citations
Semantic Scholar
Ovarian cancer immunotherapy: opportunities, progresses and challenges
Bei Liu, J. Nash, C. Runowicz, H. Swede +2 more
2010Journal of Hematology & Oncology76 citations Open access
Semantic Scholar
Regulatory T cells and Toll-like receptors: What is the missing link?
Jie Dai, Bei Liu, Zi-Hai Li
2009International Immunopharmacology76 citations Open access
Semantic Scholar
B7-H3 promotes multiple myeloma cell survival and proliferation by ROS-dependent activation of Src/STAT3 and c-Cbl-mediated degradation of SOCS3
Liang Lin, Li-Zhen Cao, Yang Liu, Ke Wang +10 more
2018Leukemia73 citations
Semantic Scholar
Molecular chaperone gp96 is a novel therapeutic target of multiple myeloma
Y. Hua, S. White-Gilbertson, Joshua Kellner, Saleh Rachidi +5 more
2013Clinical Cancer Research70 citations Open access
Semantic Scholar
Heat-shock protein gp96/grp94 is an essential chaperone for the platelet glycoprotein Ib-IX-V complex.
Matthew M. Staron, Shuang Wu, F. Hong, Aleksandra Stojanovic +4 more
2011Blood70 citations Open access
Semantic Scholar
The role of endoplasmic reticulum stress in maintaining and targeting multiple myeloma: a double-edged sword of adaptation and apoptosis
S. White-Gilbertson, Y. Hua, Bei Liu
2013Frontiers in Genetics65 citations Open access
Semantic Scholar
Molecular Chaperone GRP94/GP96 in Cancers: Oncogenesis and Therapeutic Target
Xiao-Feng Duan, Stephen Iwanowycz, S. Ngoi, Megan Hill +2 more
2021Frontiers in Oncology62 citations Open access
Semantic Scholar
CNPY2 is a Key Initiator of the PERK-CHOP Pathway of the Unfolded Protein Response
F. Hong, Bei Liu, Bill X. Wu, Jordan Morrell +5 more
2017Nature Structural &Molecular Biology60 citations Open access
Semantic Scholar
Endoplasmic reticulum heat shock protein gp96 maintains liver homeostasis and promotes hepatocellular carcinogenesis
Saleh Rachidi, Shaoli Sun, Bill X. Wu, E. Jones +8 more
2014Journal of Hepatology60 citations Open access
Semantic Scholar
Immune chaperone gp96 drives the contributions of macrophages to inflammatory colon tumorigenesis
Crystal G Morales, Saleh Rachidi, F. Hong, Shaoli Sun +7 more
2013Cancer Research60 citations Open access
Semantic Scholar
Membrane-organizing protein moesin controls Treg differentiation and antitumor immunity via TGF-&bgr; signaling
Ephraim A. Ansa-Addo, Yong-Liang Zhang, Yi Yang, George S. Hussey +9 more
2017Journal of Clinical Investigation59 citations Open access
Semantic Scholar
An integrated view of the roles and mechanisms of heat shock protein gp96-peptide complex in eliciting immune response.
Zi-Hai Li, Jie Dai, Hong Zheng, Bei Liu +1 more
2002Frontiers in Bioscience57 citations Open access
Semantic Scholar
Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
P. Yan, Hardik J. Patel, Sahil Sharma, A. Corben +22 more
2020Cell Reports56 citations Open access
Semantic Scholar
GARP Dampens Cancer Immunity by Sustaining Function and Accumulation of Regulatory T Cells in the Colon
M. Salem, C. Wallace, Maria Velegraki, Anqi Li +10 more
2019Cancer Research52 citations Open access
Semantic Scholar
Activation of NK cells by extracellular heat shock protein 70 through induction of NKG2D ligands on dendritic cells.
Y. Qiao, Bei Liu, Zi-Hai Li
2008Cancer Immunity47 citations
Semantic Scholar
B lymphocytes confer immune tolerance via cell surface GARP-TGF-β complex.
C. Wallace, Bill X. Wu, M. Salem, Ephraim A. Ansa-Addo +6 more
2018JCI Insight45 citations Open access
Semantic Scholar
Overcoming immune tolerance to cancer by heat shock protein vaccines.
Bei Liu, A. De Filippo, Zi-Hai Li
2002Molecular Cancer Therapeutics45 citations
Semantic Scholar
RNA binding protein PCBP1 is an intracellular immune checkpoint for shaping T cell responses in cancer immunity
Ephraim A. Ansa-Addo, Huai-Cheng Huang, Brian P. Riesenberg, Supinya Iamsawat +10 more
2020Science Advances43 citations Open access
Semantic Scholar
Regulatory T Cells Potentiates Suppressive Function of Expression of Heat Shock Protein gp96 TLR4 Hyperresponsiveness via Cell Surface
Jie Dai, Bei Liu, S. Ngoi, Shaoli Sun +2 more
200743 citations
Semantic Scholar
Type 2 dendritic cells mediate control of cytotoxic T cell resistant tumors
Stephen Iwanowycz, S. Ngoi, Yingqi Li, Megan Hill +5 more
2021JCI Insight42 citations Open access
Semantic Scholar
Modulation of Endoplasmic Reticulum Stress Controls CD4+ T Cell Activation and Anti-tumor Function
J. Thaxton, C. Wallace, Brian P. Riesenberg, Yong-Liang Zhang +4 more
2017Cancer immunology research42 citations Open access
Semantic Scholar
Cutting Edge: Targeting Thrombocytes to Rewire Anticancer Immunity in the Tumor Microenvironment and Potentiate Efficacy of PD-1 Blockade
Brian P. Riesenberg, Ephraim A. Ansa-Addo, J. Gutiérrez, C. Timmers +2 more
2019Journal of Immunology40 citations Open access
Semantic Scholar
Potent intestinal Th17 priming through peripheral lipopolysaccharide‐based immunization
Jeremy P. McAleer, Bei Liu, Zi-Hai Li, S. Ngoi +3 more
2010Journal of Leukocyte Biology40 citations Open access
Semantic Scholar
High expression of endoplasmic reticulum chaperone grp94 is a novel molecular hallmark of malignant plasma cells in multiple myeloma
S. Chhabra, Sandeep Jain, C. Wallace, F. Hong +1 more
2015Journal of Hematology & Oncology39 citations Open access
Semantic Scholar
Fact or fiction - identifying the elusive multiple myeloma stem cell
Joshua Kellner, Bei Liu, Yu-Bin Kang, Zi-Hai Li
2013Journal of Hematology & Oncology32 citations Open access
Semantic Scholar
Essential roles of IL‐12 and dendritic cells but not IL‐23 and macrophages in lupus‐like diseases initiated by cell surface HSP gp96
Jie Dai, Bei Liu, D. Cua, Zi-Hai Li
2007European Journal of Immunology32 citations Open access
Semantic Scholar
α7 Helix Region of αI Domain Is Crucial for Integrin Binding to Endoplasmic Reticulum Chaperone gp96
F. Hong, Bei Liu, G. Chiosis, D. Gewirth +1 more
2013Journal of Biological Chemistry30 citations Open access
Semantic Scholar
Specific Commensal Bacterium Critically Regulates Gut Microbiota Osteoimmunomodulatory Actions During Normal Postpubertal Skeletal Growth and Maturation
J. Hathaway-Schrader, Nicole A Poulides, M. Carson, J. Kirkpatrick +8 more
2020JBMR Plus29 citations Open access
Semantic Scholar
Mapping the Interactome of a Major Mammalian Endoplasmic Reticulum Heat Shock Protein 90
F. Hong, Saleh Mohammad Rachidi, Deborah H. Lundgren, David T. Han +9 more
2017PLoS ONE29 citations Open access
Semantic Scholar
--GRP94 Regulates M1 Macrophage Polarization and Insulin Resistance.
Lili Song, Do-sung Kim, Wen-Yu Gou, Jing-Jing Wang +6 more
2020American Journal of Physiology. Endocrinology and Metabolism26 citations Open access
Semantic Scholar
Pseudopodium-enriched atypical kinase 1 mediates angiogenesis by modulating GATA2-dependent VEGFR2 transcription
Huawei Wang, John D. Lapek, Ken Fujimura, J. Strnádel +11 more
2018Cell Discovery26 citations Open access
Semantic Scholar
Toll-like receptor agonist therapy can profoundly augment the antitumor activity of adoptively transferred CD8+ T cells without host preconditioning
Michelle H. Nelson, Jacob S. Bowers, Stefanie R. Bailey, Marshall A. Diven +6 more
2016Journal of Immunotherapy for Cancer26 citations Open access
Semantic Scholar

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