Skip to content

Home Search Authors Pakistan News Saved

SciRah

SciRah does not host or store research papers. Results come live from free, official scholarly APIs, and every paper links back to its original source.

Data sources

OpenAlex
Semantic Scholar
Crossref
CORE
arXiv
PubMed

Privacy policy Terms of service

P. Yan · SciRah

Researcher profile · Semantic Scholar

P. Yan

Share profile

P. Yan — researcher profile on SciRah

h-index: 26
Works: 50
Citations: 2,409

Most-cited papers

The epichaperome is an integrated chaperome network that facilitates tumour survival
Anna Rodina, Tai Wang, P. Yan, E. D. Gomes +39 more
2016Nature272 citations Open access
Semantic Scholar
Paralog-selective Hsp90 inhibitors define tumor-specific regulation of Her2
Pallav D. Patel, P. Yan, P. Seidler, Hardik J. Patel +8 more
2013Nature Chemical Biology196 citations Open access
Semantic Scholar
Mitochondrial aldehyde dehydrogenase-2 (ALDH2) Glu504Lys polymorphism contributes to the variation in efficacy of sublingual nitroglycerin.
Yi-Feng Li, Dandan Zhang, W. Jin, C. Shao +12 more
2006Journal of Clinical Investigation180 citations Open access
Semantic Scholar
Hsp90 inhibition results in autophagy-mediated proteasome-independent degradation of IκB kinase (IKK)
G. Qing, P. Yan, G. Xiao
2006Cell Research167 citations Open access
Semantic Scholar
Downregulation of miR-193b contributes to enhance urokinase-type plasminogen activator (uPA) expression and tumor progression and invasion in human breast cancer
Xin-Xiang Li, P. Yan, Z. Shao
2009Oncogene159 citations Open access
Semantic Scholar
Hsp90 regulates processing of NF-κB2 p100 involving protection of NF-κB-inducing kinase (NIK) from autophagy-mediated degradation
G. Qing, P. Yan, Z. Qu, Hu-Dan Liu +1 more
2007Cell Research108 citations
Semantic Scholar
Identification of an Allosteric Pocket on Human Hsp70 Reveals a Mode of Inhibition of This Therapeutically Important Protein
Anna Rodina, Pallav D. Patel, Yanlong Kang, Yogita Patel +14 more
2013Chemistry and Biology103 citations Open access
Semantic Scholar
PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation.
P. Yan, Jing Fu, Z. Qu, Shi-Rong Li +3 more
2009Blood94 citations Open access
Semantic Scholar
The tumor suppressor gene WWOX links the canonical and noncanonical NF-κB pathways in HTLV-I Tax-mediated tumorigenesis.
Jing Fu, Z. Qu, P. Yan, Chie Ishikawa +3 more
2011Blood82 citations Open access
Semantic Scholar
The epichaperome is a mediator of toxic hippocampal stress and leads to protein connectivity-based dysfunction
M. C. Inda, Suhasini Joshi, Tai Wang, Alexander Bolaender +35 more
2020Nature Communications79 citations Open access
Semantic Scholar
Epigenetic Repression of PDZ-LIM Domain-containing Protein 2
Z. Qu, Jing Fu, P. Yan, Jing Hu +2 more
2010Journal of Biological Chemistry71 citations Open access
Semantic Scholar
DNA methylation-dependent repression of PDZ-LIM domain-containing protein 2 in colon cancer and its role as a potential therapeutic target
Z. Qu, P. Yan, Jing Fu, Jing Jiang +3 more
2010Cancer Research65 citations Open access
Semantic Scholar
The effect of dopamine D2, D5 receptor and transporter (SLC6A3) polymorphisms on the cue‐elicited heroin craving in Chinese
Yi-Feng Li, C. Shao, Dandan Zhang, Min Zhao +5 more
2006American Journal of Medical Genetics Part B: Neuropsychiatric Genetics62 citations
Semantic Scholar
Structure–Activity Relationship in a Purine-Scaffold Compound Series with Selectivity for the Endoplasmic Reticulum Hsp90 Paralog Grp94
Hardik J. Patel, Pallav D. Patel, Stefan O. Ochiana, P. Yan +14 more
2015Journal of Medicinal Chemistry60 citations Open access
Semantic Scholar
Effect of mu-opioid receptor gene polymorphisms on heroin-induced subjective responses in a Chinese population.
Dandan Zhang, C. Shao, M. Shao, P. Yan +9 more
2007Biological Psychiatry60 citations
Semantic Scholar
Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone
P. Yan, Hardik J. Patel, Sahil Sharma, A. Corben +22 more
2020Cell Reports56 citations Open access
Semantic Scholar
Paradigms for precision medicine in epichaperome cancer therapy
N. Pillarsetty, K. Jhaveri, Tony Taldone, Eloisi Caldas-Lopes +29 more
2019Cancer Cell54 citations Open access
Semantic Scholar
Hsp90 regulates processing of NF-kappa B2 p100 involving protection of NF-kappa B-inducing kinase (NIK) from autophagy-mediated degradation.
G. Qing, P. Yan, Z. Qu, Hu-Dan Liu +1 more
2007Cell Research53 citations
Semantic Scholar
Molecular determinants of PDLIM2 in suppressing HTLV-I Tax-mediated tumorigenesis
Jing Fu, P. Yan, Shi-Rong Li, Z. Qu +1 more
2010Oncogene51 citations Open access
Semantic Scholar
Targeting Autophagic Regulation of NF-kappaB in HTLV-I Transformed Cells by Geldanamycin: Implications for Therapeutic Interventions
P. Yan, G. Qing, Z. Qu, Chang‐chih Wu +2 more
2007Autophagy51 citations Open access
Semantic Scholar
Systems-level analyses of protein-protein interaction network dysfunctions via epichaperomics identify cancer-specific mechanisms of stress adaptation
Anna Rodina, Chao-Xiong Xu, Chander S. Digwal, Suhasini Joshi +27 more
2023Nature Communications46 citations Open access
Semantic Scholar
Causative role of PDLIM2 epigenetic repression in lung cancer and therapeutic resistance
Fan Sun, Liwen Li, P. Yan, Jing-Jiao Zhou +3 more
2019Nature Communications45 citations Open access
Semantic Scholar
Human T-cell leukemia virus type I-mediated repression of PDZ-LIM domain-containing protein 2 involves DNA methylation but independent of the viral oncoprotein tax.
P. Yan, Z. Qu, Chie Ishikawa, N. Mori +1 more
2009Neoplasia44 citations Open access
Semantic Scholar
A Chemical Biology Approach to the Chaperome in Cancer—HSP90 and Beyond
Tony Taldone, Tai Wang, Anna Rodina, N. Pillarsetty +9 more
2019Cold Spring Harbor Perspectives in Biology39 citations Open access
Semantic Scholar
How Aberrant N-Glycosylation Can Alter Protein Functionality and Ligand Binding: an Atomistic View
Matteo Castelli, P. Yan, Anna Rodina, Chander S. Digwal +4 more
2022bioRxiv30 citations Open access
Semantic Scholar
Chemical tools for epichaperome-mediated interactome dysfunctions of the central nervous system
Alexander Bolaender, D. Zatorska, Hua-Zhong He, Suhasini Joshi +37 more
2021Nature Communications30 citations Open access
Semantic Scholar
Affinity Purification Probes of Potential Use To Investigate the Endogenous Hsp70 Interactome in Cancer
Anna Rodina, Tony Taldone, Yanlong Kang, Pallav D. Patel +17 more
2014ACS Chemical Biology24 citations Open access
Semantic Scholar
Disease-specific interactome alterations via epichaperomics: the case for Alzheimer’s disease
S. Ginsberg, T. Neubert, Sahil Sharma, Chander S. Digwal +4 more
2021The FEBS Journal21 citations Open access
Semantic Scholar
Pharmacologically controlling protein-protein interactions through epichaperomes for therapeutic vulnerability in cancer
Suhasini Joshi, E. D. Gomes, Tai Wang, A. Corben +36 more
2021Communications Biology19 citations Open access
Semantic Scholar
Chaperome Networks–Redundancy and Implications for Cancer Treatment
P. Yan, Tai Wang, M. Guzman, Radu I Peter +1 more
2020Advances in Experimental Medicine and Biology19 citations Open access
Semantic Scholar
Reply to ‘H-STS, L-STS and KRJ-I are not authentic GEPNET cell lines’
Mariano J. Alvarez, P. Yan, M. Alpaugh, M. Bowden +17 more
2019Nature Genetics15 citations Open access
Semantic Scholar
Improving PD-1 blockade plus chemotherapy for complete remission of lung cancer by nanoPDLIM2
Fan Sun, P. Yan, Ya-Dong Xiao, Hong-Qiao Zhang +3 more
2023bioRxiv13 citations Open access
Semantic Scholar
B pathways in HTLV-I Tax-mediated tumorigenesis κ noncanonical NF- links the canonical and WWOX The tumor suppressor gene
Jing Fu, P. Yan, Chie Ishikawa, R. Aqeilan +1 more
201113 citations
Semantic Scholar
Unbiased Assessment of H-STS cells as high-fidelity models for gastro-enteropancreatic neuroendocrine tumor drug mechanism of action analysis
Mariano J. Alvarez, P. Yan, M. Alpaugh, M. Bowden +17 more
2019bioRxiv12 citations Open access
Semantic Scholar
Phosphorylation-driven epichaperome assembly is a regulator of cellular adaptability and proliferation
Tanaya Roychowdhury, Seth McNutt, Chiranjeevi Pasala, Hieu T. Nguyen +28 more
2024Nature Communications6 citations Open access
Semantic Scholar
Bisubstrate-Type Chemical Probes Identify GRP94 as a Potential Target of Cytosine-Containing Adenosine Analogs
Dany Pechalrieu, Fanny Assemat, L. Halby, M. Marcellin +7 more
2020ACS Chemical Biology6 citations Open access
Semantic Scholar
Phosphorylation-Driven Epichaperome Assembly: A Critical Regulator of Cellular Adaptability and Proliferation
Seth W McNutt, Tanaya Roychowdhury, Chiranjeevi Pasala, Hieu T. Nguyen +28 more
2024Research Square4 citations Open access
Semantic Scholar
Coordination of the canonical and noncanonical IKK/NF-κB signaling pathways in HTLV-I Tax-mediated tumorigenesis
Jing Fu, Z. Qu, P. Yan, Shi-Rong Li +6 more
2011Retrovirology4 citations Open access
Semantic Scholar
Designing Multimodal Human–Computer Interaction for K–12 Learning: Research Design, System Architecture, and Field Evaluation of an AI Teaching Agent
Hui Liu, Chuangqi Li, Ziyu Liu, Shuxiao Yang +2 more
2026International Journal of Human-Computer Interaction2 citations
Semantic Scholar
NanoPDLIM2 enhanced efficacy of PD-1 blockade and chemotherapy in mouse lung 1 cancers 2
Fan Sun, P. Yan, Ya-Dong Xiao, Hong-Qiao Zhang +3 more
20232 citations
Semantic Scholar
Abstract 5444: Development of a noninvasive assay to determine drug concentration in tumor during hsp90 inhibitor therapy
Tony Taldone, N. Pillarsetty, M. Dunphy, J. Gerecitano +28 more
20152 citations
Semantic Scholar
Selective GRP94 inhibitors and uses thereof
加芙列拉基奥西斯, P. Yan, 帕拉维帕特尔, 哈迪克 J. 帕特尔 +4 more
20141 citations
Semantic Scholar
The tumor suppressor gene wwox links the canonical and non-canonical NF-κ B pathways in HTLV-I Tax-mediated tumorigenesis Running title : WWOX in Tax tumorigenesis
Jing Fu, Z. Qu, P. Yan, Chie Ishikawa +3 more
20101 citations
Semantic Scholar
Neutrophil extracellular trap related risk score exhibits crucial prognostic value in skin cutaneous melanoma, associating with distinct immune characteristics
Hai-Yang Zhang, Xiaoqing Bi, P. Yan, Congcong Wang
2024Skin research and technology0 citations Open access
Semantic Scholar
Abstract LB-003: OncoMatch: Unbiased, quantitative assessment of cancer model fidelity for drug sensitivity and mechanism of action elucidation
Mariano J. Alvarez, P. Yan, M. Alpaugh, M. Bowden +17 more
2020Bioinformatics, Convergence Science, and Systems Biology0 citations
Semantic Scholar
Abstract 4716: Tumor-specific regulation of receptor tyrosine kinases by Grp94
P. Yan, Hardik J. Patel, Pallav D. Patel, Stefan O. Ochiana +8 more
20150 citations
Semantic Scholar
Abstract 1733: Development of chemical tools to study the endogenous Hsp70 interactome in malignant cells
Anna Rodina, Tony Taldone, Yanlong Kang, Pallav D. Patel +16 more
20150 citations
Semantic Scholar
Abstract 2831: Development of selective GRP94 inhibitors for the treatment of cancer
Stefan O. Ochiana, Tony Taldone, Hardik J. Patel, Pallav D. Patel +6 more
20150 citations
Semantic Scholar
Abstract 3329: Investigations into the tumor specific regulation of HER2 by Grp94 in breast cancer
P. Yan, Hardik J. Patel, Cheng-Hua Yang, Tony Taldone +1 more
20140 citations
Semantic Scholar
Regulation of HTLV-I oncoprotein Tax by PDLIM2
P. Yan
20100 citations
Semantic Scholar

Frequent co-authors

Invite them to SciRah by sharing their profile.

G. Chiosis×25
Invite
G. Chiosis — researcher profile on SciRah
Tony Taldone×17
Invite
Tony Taldone — researcher profile on SciRah
Anna Rodina×16
Invite
Anna Rodina — researcher profile on SciRah
Z. Qu×14
Invite
Z. Qu — researcher profile on SciRah

×12

Invite

G. Xiao — researcher profile on SciRah

Invite

Tai Wang — researcher profile on SciRah

Hardik J. Patel×9

Invite

Hardik J. Patel — researcher profile on SciRah

Cheng-Hua Yang×9

Invite

Cheng-Hua Yang — researcher profile on SciRah

Palak Panchal×9

Invite

Palak Panchal — researcher profile on SciRah

H. Erdjument-Bromage×9

Invite

H. Erdjument-Bromage — researcher profile on SciRah

Invite

M. Alpaugh — researcher profile on SciRah

Pallav D. Patel×8

Invite

Pallav D. Patel — researcher profile on SciRah