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B. Wouters · SciRah

Researcher profile · Semantic Scholar

B. Wouters

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B. Wouters — researcher profile on SciRah

h-index: 70
Works: 285
Citations: 27K

Most-cited papers

International validation of the consensus Immunoscore for the classification of colon cancer: a prognostic and accuracy study.
F. Pagès, B. Mlecnik, F. Marliot, G. Bindea +95 more
2018The Lancet1,858 citations
Semantic Scholar
The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress
P. van Galen, Antonija Krešo, Nathan Mbong, D. Kent +12 more
2014Nature355 citations Open access
Semantic Scholar
GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer
Qin Wu, W. Ba-alawi, Geneviève Deblois, Jennifer Cruickshank +25 more
2019Nature Communications259 citations Open access
Semantic Scholar
Association of Distinct Mutational Signatures With Correlates of Increased Immune Activity in Pancreatic Ductal Adenocarcinoma
Ashton A. Connor, R. Denroche, G. Jang, Lee E. Timms +36 more
2017JAMA Oncology247 citations Open access
Semantic Scholar
ONECUT2 is a driver of neuroendocrine prostate cancer
Haiyang Guo, Xinpei Ci, Musaddeque Ahmed, Junjie T Hua +36 more
2019Nature Communications228 citations Open access
Semantic Scholar
Hypoxia-activated prodrugs: paths forward in the era of personalised medicine
F. Hunter, B. Wouters, W. Wilson
2016British Journal of Cancer208 citations Open access
Semantic Scholar
Integration of Genomic and Transcriptional Features in Pancreatic Cancer Reveals Increased Cell Cycle Progression in Metastases
Ashton A. Connor, R. Denroche, Gun-Ho Jang, M. Lemire +41 more
2019Cancer Cell203 citations Open access
Semantic Scholar
Molecular targeting of hypoxia in radiotherapy☆
S. Rey, L. Schito, M. Koritzinsky, B. Wouters
2017Advanced Drug Delivery Reviews157 citations
Semantic Scholar
Multicenter International Society for Immunotherapy of Cancer Study of the Consensus Immunoscore for the Prediction of Survival and Response to Chemotherapy in Stage III Colon Cancer.
B. Mlecnik, C. Bifulco, G. Bindea, F. Marliot +88 more
2020Journal of Clinical Oncology155 citations Open access
Semantic Scholar
Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma
K. Michealraj, Sachin A. Kumar, Leo J Y Kim, F. Cavalli +62 more
2020Cell113 citations Open access
Semantic Scholar
Targeting Hypoxia-Inducible Factors for Antiangiogenic Cancer Therapy.
S. Rey, L. Schito, B. Wouters, S. Eliasof +1 more
2017Trends in Cancer106 citations
Semantic Scholar
PTP1B regulates non-mitochondrial oxygen consumption via RNF213 to promote tumour survival during hypoxia
Robert S. Banh, Caterina Iorio, R. Marcotte, Yang Xu +21 more
2016Nature Cell Biology100 citations Open access
Semantic Scholar
A 3D engineered tumour for spatial snap-shot analysis of cell metabolism and phenotype in hypoxic gradients
D. Rodenhizer, E. Gaude, Dan Cojocari, R. Mahadevan +3 more
2015Nature Materials97 citations Open access
Semantic Scholar
Hypoxia and Predicting Radiation Response.
R. Hill, R. Bristow, A. Fyles, M. Koritzinsky +2 more
2015Seminars in Radiation Oncology88 citations
Semantic Scholar
Hypoxia increases genome-wide bivalent epigenetic marking by specific gain of H3K27me3
P. Prickaerts, M. Adriaens, T. van den Beucken, Elizabeth Koch +7 more
2016Epigenetics & Chromatin86 citations Open access
Semantic Scholar
Identification of P450 Oxidoreductase as a Major Determinant of Sensitivity to Hypoxia-Activated Prodrugs.
F. Hunter, R. Young, Z. Shalev, Ravi N. Vellanki +14 more
2015Cancer Research68 citations Open access
Semantic Scholar
Metabolic targeting of HIF-dependent glycolysis reduces lactate, increases oxygen consumption and enhances response to high-dose single-fraction radiotherapy in hypoxic solid tumors
E. Leung, R. Cairns, N. Chaudary, Ravi N. Vellanki +7 more
2017BMC Cancer63 citations Open access
Semantic Scholar
Effect of pantoprazole to enhance activity of docetaxel against human tumour xenografts by inhibiting autophagy
Qian Tan, A. Joshua, J. Saggar, M. Yu +6 more
2015British Journal of Cancer56 citations Open access
Semantic Scholar
Evofosfamide for the treatment of human papillomavirus-negative head and neck squamous cell carcinoma.
S. Jamieson, P. Tsai, Maria Kondratyev, Pratha Budhani +31 more
2018JCI Insight52 citations Open access
Semantic Scholar
CHCHD2 Is Coamplified with EGFR in NSCLC and Regulates Mitochondrial Function and Cell Migration
Yuhong Wei, Ravi N. Vellanki, É. Coyaud, V. Ignatchenko +11 more
2015Molecular Cancer Research52 citations
Semantic Scholar
Irradiation-induced damage and the DNA damage response
C. Vens, M. Koritzinsky, B. Wouters
2018Basic Clinical Radiobiology47 citations
Semantic Scholar
Pantoprazole Affecting Docetaxel Resistance Pathways via Autophagy (PANDORA): Phase II Trial of High Dose Pantoprazole (Autophagy Inhibitor) with Docetaxel in Metastatic Castration-Resistant Prostate Cancer (mCRPC).
A. Hansen, I. Tannock, A. Templeton, E. Chen +9 more
2019The Oncologist43 citations Open access
Semantic Scholar
Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells
Evelyne Lima-Fernandes, Alex Murison, Tiago da Silva Medina, Ya-Dong Wang +15 more
2019Nature Communications42 citations Open access
Semantic Scholar
Quantitative Visualization of Hypoxia and Proliferation Gradients Within Histological Tissue Sections
M. Zaidi, Fred Fu, Dan Cojocari, T. McKee +1 more
2019bioRxiv40 citations Open access
Semantic Scholar
Erratum: A three-dimensional engineered tumour for spatial snapshot analysis of cell metabolism and phenotype in hypoxic gradients.
D. Rodenhizer, E. Gaude, Dan Cojocari, R. Mahadevan +3 more
2016Nature Materials40 citations Open access
Semantic Scholar
In Vivo Imaging Reveals Significant Tumor Vascular Dysfunction and Increased Tumor Hypoxia-Inducible Factor-1α Expression Induced by High Single-Dose Irradiation in a Pancreatic Tumor Model.
A. Maeda, Yonghong Chen, J. Bu, H. Mujcic +2 more
2017International Journal of Radiation Oncology, Biology, Physics38 citations
Semantic Scholar
Drug-induced reactive oxygen species (ROS) rely on cell membrane properties to exert anticancer effects
H. Molavian, Aaron Goldman, Colin Phipps, M. Kohandel +3 more
2016Scientific Reports38 citations Open access
Semantic Scholar
Up-regulation of autophagy is a mechanism of resistance to chemotherapy and can be inhibited by pantoprazole to increase drug sensitivity
Qian Tan, A. M. Joshua, M. Wang, R. Bristow +3 more
2017Cancer Chemotherapy and Pharmacology37 citations
Semantic Scholar
Radiobiological Intercomparison of the 160 MeV and 230 MeV Proton Therapy Beams at the Harvard Cyclotron Laboratory and at Massachusetts General Hospital
B. Wouters, L. Skarsgard, L. Gerweck, A. Carabe-Fernandez +8 more
2015Radiation Research37 citations
Semantic Scholar
High tumor interstitial fluid pressure identifies cervical cancer patients with improved survival from radiotherapy plus cisplatin versus radiotherapy alone
M. Milosevic, M. Pintilie, D. Hedley, R. Bristow +5 more
2014International Journal of Cancer34 citations
Semantic Scholar
TePhe, a tellurium-containing phenylalanine mimic, allows monitoring of protein synthesis in vivo with mass cytometry
Jay Bassan, L. Willis, Ravi N. Vellanki, Alan V Nguyen +3 more
2019Proceedings of the National Academy of Sciences of the United States of America32 citations Open access
Semantic Scholar
Multicenter International Study of the Consensus Immunoscore for the Prediction of Relapse and Survival in Early-Stage Colon Cancer
B. Mlecnik, A. Lugli, G. Bindea, F. Marliot +87 more
2023Cancers31 citations Open access
Semantic Scholar
The mTOR Targets 4E-BP1/2 Restrain Tumor Growth and Promote Hypoxia Tolerance in PTEN-driven Prostate Cancer
M. Ding, T. van der Kwast, Ravi N. Vellanki, W. Foltz +5 more
2018Molecular Cancer Research31 citations Open access
Semantic Scholar
NOX4 links metabolic regulation in pancreatic cancer to endoplasmic reticulum redox vulnerability and dependence on PRDX4
P. Jain, A. Dvorkin-Gheva, Erik Mollen, Lucie Malbeteau +13 more
2020Science Advances30 citations Open access
Semantic Scholar
MATE2 Expression Is Associated with Cancer Cell Response to Metformin
S. Chowdhury, E. Yung, M. Pintilie, Hala Muaddi +12 more
2016PLoS ONE29 citations Open access
Semantic Scholar
Isotopologous Organotellurium Probes Reveal Dynamic Hypoxia In Vivo with Cellular Resolution.
L. Edgar, Ravi N. Vellanki, T. McKee, D. Hedley +2 more
2016Angewandte Chemie29 citations
Semantic Scholar
Quantitative analysis of ChIP-seq data uncovers dynamic and sustained H3K4me3 and H3K27me3 modulation in cancer cells under hypoxia
M. Adriaens, P. Prickaerts, M. Chan-Seng-Yue, T. van den Beucken +6 more
2016Epigenetics & Chromatin28 citations Open access
Semantic Scholar
Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies
Yi Liang, Sujeeve Jeganathan, Stefano Marastoni, A. Sharp +19 more
2021Clinical Cancer Research26 citations Open access
Semantic Scholar
Development of TRACER: tissue roll for analysis of cellular environment and response
D. Rodenhizer, Dan Cojocari, B. Wouters, A. McGuigan
2016Biofabrication26 citations Open access
Semantic Scholar
Mass Spectrometry Imaging Reveals a Gradient of Cancer-like Metabolic States in the Vicinity of Cancer Not Seen in Morphometric Margins from Microscopy.
Michael Woolman, Lauren Katz, Georgia Gopinath, T. Kiyota +14 more
2021Analytical Chemistry23 citations
Semantic Scholar
Administration of Hypoxia-Activated Prodrug Evofosfamide after Conventional Adjuvant Therapy Enhances Therapeutic Outcome and Targets Cancer-Initiating Cells in Preclinical Models of Colorectal Cancer
J. Haynes, T. McKee, A. Haller, Ya-Dong Wang +13 more
2018Clinical Cancer Research21 citations Open access
Semantic Scholar
An Engineered Patient‐Derived Tumor Organoid Model That Can Be Disassembled to Study Cellular Responses in a Graded 3D Microenvironment
Natalie Landon-Brace, J. L. Cadavid, Simon Latour, I. Co +8 more
2021Advanced Functional Materials20 citations
Semantic Scholar
In situ tissue pathology from spatially encoded mass spectrometry classifiers visualized in real time through augmented reality
Michael Woolman, Jimmy Qiu, C. Kuzan-Fischer, I. Ferry +17 more
2020Chemical Science20 citations Open access
Semantic Scholar
Clinical Performance of the Consensus Immunoscore in Colon Cancer in the Asian Population from the Multicenter International SITC Study
B. Mlecnik, T. Torigoe, G. Bindea, B. Popivanova +89 more
2022Cancers18 citations Open access
Semantic Scholar
Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer
Stefano Marastoni, A. Madariaga, A. Pesic, Sreesha N. Nair +22 more
2022Cancer Research Communications17 citations Open access
Semantic Scholar
An Engineered Paper‐Based 3D Coculture Model of Pancreatic Cancer to Study the Impact of Tissue Architecture and Microenvironmental Gradients on Cell Phenotype
J. L. Cadavid, Simon Latour, Ferris Nowlan, I. Co +6 more
2022Advanced Healthcare Materials16 citations
Semantic Scholar
L-alanyl-L-glutamine modified perfusate improves human lung cell functions and extend porcine ex vivo lung perfusion.
Lei Huang, O. Hough, Ravi N. Vellanki, Mamoru Takahashi +12 more
2022The Journal of Heart and Lung Transplantation15 citations
Semantic Scholar
Functional CRISPR and shRNA Screens Identify Involvement of Mitochondrial Electron Transport in the Activation of Evofosfamide
F. Hunter, Jules B. L. Devaux, F. Meng, C. Hong +13 more
2019Molecular Pharmacology13 citations Open access
Semantic Scholar
Integrating RAS Status into Prognostic Signatures for Adenocarcinomas of the Lung
M. Starmans, M. Pintilie, M. Chan-Seng-Yue, Nathalie C. Moon +13 more
2015Clinical Cancer Research12 citations Open access
Semantic Scholar
De Novo Design and Development of a Nutrient-Rich Perfusate for Ex Vivo Lung Perfusion with Cell Culture Models
Lei Huang, Ravi N. Vellanki, Zhiyuan Zhu, B. Wouters +2 more
2023International Journal of Molecular Sciences8 citations Open access
Semantic Scholar

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