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P. Mathew · SciRah

Researcher profile · Semantic Scholar

P. Mathew

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P. Mathew — researcher profile on SciRah

h-index: 35
Works: 111
Citations: 4,519

Most-cited papers

2B4, the Natural Killer and T Cell Immunoglobulin Superfamily Surface Protein, Is a Ligand for CD48
Marion H. Brown, Kent S. Boles, P. Anton van der Merwe, Vinay Kumar +2 more
1998Journal of Experimental Medicine448 citations Open access
Semantic Scholar
Cutting Edge: Lectin-Like Transcript-1 Is a Ligand for the Inhibitory Human NKR-P1A Receptor1
D. Rosen, J. Bettadapura, Mohammed Alsharifi, P. Mathew +2 more
2005Journal of Immunology296 citations Open access
Semantic Scholar
2B4 Acts As a Non–Major Histocompatibility Complex Binding Inhibitory Receptor on Mouse Natural Killer Cells
Kyung-Mi Lee, M. McNerney, S. Stepp, P. Mathew +3 more
2004Journal of Experimental Medicine236 citations Open access
Semantic Scholar
2B4 (CD244) and CS1: novel members of the CD2 subset of the immunoglobulin superfamily molecules expressed on natural killer cells and other leukocytes
Kent S. Boles, S. Stepp, M. Bennett, Vinay Kumar +1 more
2001Immunological Reviews163 citations
Semantic Scholar
CS1, a novel member of the CD2 family, is homophilic and regulates NK cell function.
P. Kumaresan, W. Lai, Samuel S. Chuang, M. Bennett +1 more
2002Molecular Immunology156 citations
Semantic Scholar
Absence of mouse 2B4 promotes NK cell-mediated killing of activated CD8+ T cells, leading to prolonged viral persistence and altered pathogenesis.
S. Waggoner, R. Taniguchi, P. Mathew, Vinay Kumar +1 more
2010Journal of Clinical Investigation143 citations Open access
Semantic Scholar
Characterization of inhibitory and stimulatory forms of the murine natural killer cell receptor 2B4.
J. Schatzle, Shane Sheu, S. Stepp, P. Mathew +2 more
1999Proceedings of the National Academy of Sciences of the United States of America132 citations Open access
Semantic Scholar
2B4 (CD244)-Mediated Activation of Cytotoxicity and IFN-γ Release in Human NK Cells Involves Distinct Pathways1
Samuel S. Chuang, P. Kumaresan, P. Mathew
2001Journal of Immunology129 citations
Semantic Scholar
Perforin: more than just an effector molecule.
S. Stepp, P. Mathew, M. Bennett, G. de Saint Basile +1 more
2000Immunology today (Amsterdam. Regular ed.)127 citations
Semantic Scholar
Targeted Disruption of the 2B4 Gene in Mice Reveals an In Vivo Role of 2B4 (CD244) in the Rejection of B16 Melanoma Cells1
S. Vaidya, S. Stepp, M. McNerney, Jae-Kyung Lee +5 more
2005Journal of Immunology108 citations
Semantic Scholar
Molecular characterization of a novel human natural killer cell receptor homologous to mouse 2B4.
Kent S. Boles, H. Nakajima, Marco Colonna, Samuel S. Chuang +4 more
1999Tissue Antigens106 citations
Semantic Scholar
Requirement of homotypic NK-cell interactions through 2B4(CD244)/CD48 in the generation of NK effector functions.
Kyung-Mi Lee, J. Forman, M. McNerney, S. Stepp +12 more
2006Blood101 citations Open access
Semantic Scholar
Molecular cloning of CS1, a novel human natural killer cell receptor belonging to the CD2 subset of the immunoglobulin superfamily
Kent S. Boles, P. Mathew
2000Immunogenetics95 citations
Semantic Scholar
Cloning of a new lectin-like receptor expressed on human NK cells
Kent S. Boles, R. Barten, P. Kumaresan, J. Trowsdale +1 more
1999Immunogenetics83 citations
Semantic Scholar
CS1 (CRACC, CD319) Induces Proliferation and Autocrine Cytokine Expression on Human B Lymphocytes1
J. K. Lee, Stephen O. Mathew, S. Vaidya, P. Kumaresan +1 more
2007Journal of Immunology81 citations Open access
Semantic Scholar
Gene structure of the murine NK cell receptor 2B4: presence of two alternatively spliced isoforms with distinct cytoplasmic domains
S. Stepp, J. Schatzle, M. Bennett, Vinay Kumar +1 more
1999European Journal of Immunology78 citations Open access
Semantic Scholar
Altered expression of signalling lymphocyte activation molecule (SLAM) family receptors CS1 (CD319) and 2B4 (CD244) in patients with systemic lupus erythematosus
Jong R. Kim, Stephen O. Mathew, R. Patel, R. Pertusi +1 more
2010Clinical and Experimental Immunology73 citations Open access
Semantic Scholar
Allorecognition by murine natural killer cells: lysis of T‐lymphoblasts and rejection of bone‐marrow grafts
T. George, Y. Yu, Jing-Xuan Liu, C. Davenport +5 more
1997Immunological Reviews73 citations
Semantic Scholar
Roles of NK Cell Receptors 2B4 (CD244), CS1 (CD319), and LLT1 (CLEC2D) in Cancer
Casey Buller, P. Mathew, Stephen O. Mathew
2020Cancers70 citations Open access
Semantic Scholar
Overexpression of LLT1 (OCIL, CLEC2D) on prostate cancer cells inhibits NK cell-mediated killing through LLT1-NKRP1A (CD161) interaction
Stephen O. Mathew, P. Chaudhary, Sheila B. Powers, J. Vishwanatha +1 more
2016OncoTarget66 citations Open access
Semantic Scholar
NKp44 and Natural Cytotoxicity Receptors as Damage-Associated Molecular Pattern Recognition Receptors
Nathan C. Horton, P. Mathew
2015Frontiers in Immunology59 citations Open access
Semantic Scholar
CS1 (SLAMF7) inhibits production of proinflammatory cytokines by activated monocytes
Jong R. Kim, Nathan C. Horton, Stephen O. Mathew, P. Mathew
2013Inflammation Research58 citations
Semantic Scholar
2B4 stimulation of YT cells induces natural killer cell cytolytic function and invasiveness
Samuel S. Chuang, Myoung H. Kim, L. A. Johnson, Per Albertsson +4 more
2000Immunology56 citations Open access
Semantic Scholar
Novel Interaction between Proliferating Cell Nuclear Antigen and HLA I on the Surface of Tumor Cells Inhibits NK Cell Function through NKp44
Nathan C. Horton, Stephen O. Mathew, P. Mathew
2013PLoS ONE54 citations Open access
Semantic Scholar
Blocking LLT1 (CLEC2D, OCIL)-NKRP1A (CD161) interaction enhances natural killer cell-mediated lysis of triple-negative breast cancer cells.
A. Marrufo, Stephen O. Mathew, P. Chaudhary, Joseph D. Malaer +2 more
2018American Journal of Cancer Research51 citations
Semantic Scholar
Molecular and functional characterization of a CS1 (CRACC) splice variant expressed in human NK cells that does not contain immunoreceptor tyrosine‐based switch motifs
J. K. Lee, Kent S. Boles, P. Mathew
2004European Journal of Immunology51 citations
Semantic Scholar
The LLT1 receptor induces IFN-γ production by human natural killer cells
P. Mathew, Samuel S. Chuang, S. Vaidya, P. Kumaresan +2 more
200449 citations
Semantic Scholar
Protein kinase C is involved in 2B4 (CD244)‐mediated cytotoxicity and AP‐1 activation in natural killer cells
Samuel S. Chuang, Jae-Kyung Lee, P. Mathew
2003Immunology48 citations Open access
Semantic Scholar
Activation of murine epidermal γδ T cells through surface 2B4
G. Schuhmachers, K. Ariizumi, P. Mathew, M. Bennett +2 more
199547 citations
Semantic Scholar
Of mice and men: different functions of the murine and human 2B4 (CD244) receptor on NK cells.
S. Vaidya, P. Mathew
2006Immunology Letters46 citations
Semantic Scholar
Functional role of human NK cell receptor 2B4 (CD244) isoforms
Stephen O. Mathew, K. K. Rao, Jong R. Kim, Nowland D. Bambard +1 more
2009European Journal of Immunology41 citations Open access
Semantic Scholar
CS1 (SLAMF7, CD319) is an effective immunotherapeutic target for multiple myeloma.
Joseph D. Malaer, P. Mathew
2017American Journal of Cancer Research36 citations
Semantic Scholar
The LLT1 receptor induces IFN-gamma production by human natural killer cells.
P. Mathew, Samuel S. Chuang, S. Vaidya, P. Kumaresan +2 more
2004Molecular Immunology35 citations
Semantic Scholar
Mutational Analysis of the Human 2B4 (CD244)/CD48 Interaction: Lys68 and Glu70 in the V Domain of 2B4 Are Critical for CD48 Binding and Functional Activation of NK Cells1
Stephen O. Mathew, P. Kumaresan, J. K. Lee, Van T. Huynh +1 more
2005Journal of Immunology30 citations Open access
Semantic Scholar
Blimp-1/PRDM1 regulates the transcription of human CS1 (SLAMF7) gene in NK and B cells.
Jong R. Kim, Stephen O. Mathew, P. Mathew
2016Immunobiology29 citations
Semantic Scholar
2B4+CD8+ T cells play an inhibitory role against constrained HIV Epitopes
K. Aldy, Nathan C. Horton, P. Mathew, Stephen O. Mathew
2011Biochemical and Biophysical Research Communications - BBRC28 citations Open access
Semantic Scholar
Polymorphism in the 2B4 gene of inbred mouse strains
P. Kumaresan, Van T. Huynh, P. Mathew
1999Immunogenetics28 citations
Semantic Scholar
LLT1‐mediated Activation of IFN‐γ Production in Human Natural Killer Cells Involves ERK Signalling Pathway
Nowland D. Bambard, Stephen O. Mathew, P. Mathew
2010Scandinavian Journal of Immunology25 citations Open access
Semantic Scholar
Structure of the human natural killer cell receptor 2B4 gene and identification of a novel alternative transcript
P. Kumaresan, P. Mathew
2000Immunogenetics25 citations
Semantic Scholar
Regulation of IFN-gamma production following 2B4 activation in human NK cells.
L. A. Johnson, R. Goldfarb, P. Mathew
2000In Vivo23 citations
Semantic Scholar
2B4 (CD244, SLAMF4) and CS1 (CD319, SLAMF7) in systemic lupus erythematosus and cancer.
Joseph D. Malaer, A. Marrufo, P. Mathew
2019Clinical Immunology20 citations
Semantic Scholar
Role of LLT1 and PCNA as Natural Killer Cell Immune Evasion Strategies of HCT 116 Cells
Joseph D. Malaer, P. Mathew
2020Anticancer Research18 citations Open access
Semantic Scholar
Human natural killer cell receptor 2B4 (CD244) down-regulates its own expression by reduced promoter activity at an Ets element.
Stephen O. Mathew, S. Vaidya, Jong R. Kim, P. Mathew
2007Biochemical and Biophysical Research Communications - BBRC18 citations Open access
Semantic Scholar
A Prominent Role for Activator Protein-1 in the Transcription of the Human 2B4 (CD244) Gene in NK Cells1
Samuel S. Chuang, H. T. Pham, P. Kumaresan, P. Mathew
2001Journal of Immunology18 citations Open access
Semantic Scholar
Molecular cloning and characterization of the promoter region of murine natural killer cell receptor 2B4.
Samuel S. Chuang, Yuk-Fung Lee, S. Stepp, P. Kumaresan +1 more
1999Biochimica et Biophysica Acta18 citations
Semantic Scholar
Pillars Article: Perforin Gene Defects in Familial Hemophagocytic Lymphohistiocytosis. Science. 1999. 286: 1957–1959
S. Stepp, R. Dufourcq-Lagelouse, F. le Deist, S. Bhawan +7 more
2015Journal of Immunology14 citations
Semantic Scholar
2B4(CD244)-mediated activation of NK cells reduces metastases of B16F10 melanoma in mice.
L. Johnson, S. Vaidya, R. Goldfarb, P. Mathew
2003Anticancer Research14 citations
Semantic Scholar
YY1 and a unique DNA repeat element regulates the transcription of mouse CS1 (CD319, SLAMF7) gene.
P. Dongre, Stephen O. Mathew, I. Akopova, I. Gryczynski +1 more
2013Molecular Immunology13 citations
Semantic Scholar
Molecular cloning of transmembrane and soluble forms of a novel rat natural killer cell receptor related to 2B4
P. Kumaresan, S. Stepp, M. Bennett, Vinay Kumar +1 more
2000Immunogenetics11 citations
Semantic Scholar
A novel ligand on astrocytes interacts with natural cytotoxicity receptor NKp44 regulating immune response mediated by NK cells
Kelly E. Bowen, Stephen O. Mathew, K. Borgmann, A. Ghorpade +1 more
2018PLoS ONE9 citations Open access
Semantic Scholar

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