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G. Studzinski · SciRah

Researcher profile · Semantic Scholar

G. Studzinski

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G. Studzinski — researcher profile on SciRah

h-index: 46
Works: 246
Citations: 6,870

Most-cited papers

MicroRNAs181 regulate the expression of p27Kip1 in human myeloid leukemia cells induced to differentiate by 1,25-dihydroxyvitamin D3
Xue-Ning Wang, E. Gocek, Chang-gong Liu, G. Studzinski
2009Cell Cycle140 citations Open access
Semantic Scholar
Vitamin D and differentiation in cancer
E. Gocek, G. Studzinski
2009Critical reviews in clinical laboratory sciences130 citations Open access
Semantic Scholar
Retinoblastoma Protein and CCAAT/Enhancer-Binding Protein β Are Required for 1,25-Dihydroxyvitamin D3-Induced Monocytic Differentiation of HL60 Cells
Yan Ji, G. Studzinski
2004Cancer Research111 citations Open access
Semantic Scholar
MicroRNA-32 upregulation by 1,25-dihydroxyvitamin D3 in human myeloid leukemia cells leads to Bim targeting and inhibition of AraC-induced apoptosis
E. Gocek, Xue-Ning Wang, Xiu-Ping Liu, Chang-gong Liu +1 more
2011Cancer Research102 citations Open access
Semantic Scholar
Non-receptor protein tyrosine kinases signaling pathways in normal and cancer cells
E. Gocek, A. Moulas, G. Studzinski
2014Critical reviews in clinical laboratory sciences91 citations
Semantic Scholar
Cooperative antitumor effects of vitamin D3 derivatives and rosemary preparations in a mouse model of myeloid leukemia
Hagar Sharabani, E. Izumchenko, Qing Wang, Rita Kreinin +8 more
2006International Journal of Cancer87 citations Open access
Semantic Scholar
Distinct combinatorial effects of the plant polyphenols curcumin, carnosic acid and silibinin on proliferation and apoptosis in acute myeloid leukemia cells
Stella Pesakhov, M. Khanin, G. Studzinski, M. Danilenko
2010Nutrition and Cancer77 citations Open access
Semantic Scholar
Cooperation between antioxidants and 1,25‐dihydroxyvitamin D3 in induction of leukemia HL60 cell differentiation through the JNK/AP‐1/Egr‐1 pathway
Q. Wang, Hagar M. S. Salman, M. Danilenko, G. Studzinski
2005Journal of Cellular Physiology77 citations
Semantic Scholar
AKT Pathway is Activated by 1,25-Dihydroxyvitamin D3 and Participates in its Anti-Apoptotic Effect and Cell Cycle Control in Differentiating HL60 Cells
Ying-Yu Zhang, Jing Zhang, G. Studzinski
2006Cell Cycle75 citations Open access
Semantic Scholar
Role of vitamin D in cytotoxic T lymphocyte immunity to pathogens and cancer
Surojit Sarkar, M. Hewison, G. Studzinski, Yan-Chun Li +1 more
2016Critical reviews in clinical laboratory sciences73 citations
Semantic Scholar
The Nrf2 transcription factor is a positive regulator of myeloid differentiation of acute myeloid leukemia cells
I. Bobilev, V. Novik, I. Levi, O. Shpilberg +4 more
2011Cancer Biology & Therapy67 citations Open access
Semantic Scholar
Regulation of C/EBPβ isoforms by MAPK pathways in HL60 cells induced to differentiate by 1,25-dihydroxyvitamin D3
E. Marcinkowska, E. Garay, E. Gocek, A. Chrobak +2 more
200667 citations Open access
Semantic Scholar
Vitamin D3-driven signals for myeloid cell differentiation - Implications for differentiation therapy
P. Hughes, E. Marcinkowska, E. Gocek, G. Studzinski +1 more
2009Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis64 citations Open access
Semantic Scholar
Synergistic Antileukemic Activity of Carnosic Acid-Rich Rosemary Extract and the 19-nor Gemini Vitamin D Analogue in a Mouse Model of Systemic Acute Myeloid Leukemia
A. Shabtay, Hagar Sharabani, Zeev Barvish, M. Kafka +6 more
2008Oncology61 citations Open access
Semantic Scholar
Enhancement by other compounds of the anti-cancer activity of vitamin D(3) and its analogs.
M. Danilenko, G. Studzinski
2004Experimental Cell Research61 citations
Semantic Scholar
Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3
H. Halicka, Hong Zhao, Jiangwei Li, F. Trã¡ganos +2 more
2012Aging60 citations Open access
Semantic Scholar
Cancer-selective cytotoxic Ca2+ overload in acute myeloid leukemia cells and attenuation of disease progression in mice by synergistically acting polyphenols curcumin and carnosic acid
Stella Pesakhov, M. Nachliely, Zeev Barvish, N. Aqaqe +6 more
2016OncoTarget59 citations Open access
Semantic Scholar
The rationale for deltanoids in therapy for myeloid leukemia: role of KSR-MAPK-C/EBP pathway.
G. Studzinski, Xue-Ning Wang, Yan Ji, Q. Wang +3 more
2005Journal of Steroid Biochemistry and Molecular Biology58 citations Open access
Semantic Scholar
Inhibition of Cot1/Tlp2 oncogene in AML cells reduces ERK5 activation and upregulates p27Kip1 concomitant with enhancement of differentiation and cell cycle arrest induced by silibinin and 1,25-dihydroxyvitamin D3
Xue-Ning Wang, E. Gocek, V. Novik, J. Harrison +2 more
2010Cell Cycle50 citations Open access
Semantic Scholar
Induction of kinase suppressor of RAS-1(KSR-1) gene by 1, α25-dihydroxyvitamin D3 in human leukemia HL60 cells through a vitamin D response element in the 5′-flanking region
Xue-Ning Wang, Tian-Tian Wang, John H. White, G. Studzinski
2006Oncogene38 citations Open access
Semantic Scholar
ERK 5/MAPK PATHWAY HAS A MAJOR ROLE IN 1α,25-(OH)2 VITAMIN D3-INDUCED TERMINAL DIFFERENTIATION OF MYELOID LEUKEMIA CELLS
Xue-Ning Wang, Stella Pesakhov, Ashley Weng, M. Kafka +5 more
2013Journal of Steroid Biochemistry and Molecular Biology36 citations Open access
Semantic Scholar
Induction of differentiation of human leukemia cells by combinations of COX inhibitors and 1, 25-dihydroxyvitamin D3 involves Raf1 but not Erk 1/2 signaling
F. Jamshidi, Jing Zhang, J. Harrison, Xue-Ning Wang +1 more
2008Cell Cycle34 citations Open access
Semantic Scholar
Regulation of C/EBPbeta isoforms by MAPK pathways in HL60 cells induced to differentiate by 1,25-dihydroxyvitamin D3.
E. Marcinkowska, E. Garay, E. Gocek, A. Chrobak +2 more
2006Experimental Cell Research34 citations
Semantic Scholar
1,25-dihydroxyvitamin D3 enhances the apoptotic activity of MDM2 antagonist nutlin-3a in acute myeloid leukemia cells expressing wild-type p53
Thelma O Thompson, M. Andreeff, G. Studzinski, L. Vassilev
2010Molecular Cancer Therapeutics32 citations Open access
Semantic Scholar
Translational study of vitamin D differentiation therapy of myeloid leukemia: effects of the combination with a p38 MAPK inhibitor and an antioxidant
Q. Wang, J. Harrison, M. Uskoković, A. Kutner +1 more
2005Leukemia32 citations Open access
Semantic Scholar
Expression of human kinase suppressor of Ras 2 (hKSR-2) gene in HL60 leukemia cells is directly upregulated by 1,25-dihydroxyvitamin D(3) and is required for optimal cell differentiation.
Xue-Ning Wang, Tian-Tian Wang, John H. White, G. Studzinski
2007Experimental Cell Research31 citations Open access
Semantic Scholar
Raf‐1 signaling is required for the later stages of 1,25‐dihydroxyvitamin D3‐induced differentiation of HL60 cells but is not mediated by the MEK/ERK module
Xue-Ning Wang, G. Studzinski
2006Journal of Cellular Physiology31 citations Open access
Semantic Scholar
ERK5 Pathway Regulates Transcription Factors Important for Monocytic Differentiation of Human Myeloid Leukemia Cells
Xue-Ning Wang, Stella Pesakhov, Jonathan S. Harrison, M. Danilenko +1 more
2014Journal of Cellular Physiology28 citations Open access
Semantic Scholar
Vitamin D receptor signals regulate effector and memory CD8 T cell responses to infections in mice.
Yevgeniy Yuzefpolskiy, F. Baumann, L. Penny, G. Studzinski +2 more
2014Journal of NutriLife27 citations Open access
Semantic Scholar
Vitamin D receptor signaling of monocytic differentiation in human leukemia cells: role of MAPK pathways in transcription factor activation.
G. Studzinski, E. Garay, R. Patel, Jing Zhang +1 more
2006Current Topics in Medicinal Chemistry27 citations
Semantic Scholar
C-Jun N-terminal kinase 2 (JNK2) antagonizes the signaling of differentiation by JNK1 in human myeloid leukemia cells resistant to vitamin D
Xiangwen Chen-Deutsch, E. Garay, Jing Zhang, J. Harrison +1 more
2009Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis26 citations Open access
Semantic Scholar
Silibinin can induce differentiation as well as enhance vitamin D3 -induced differentiation of human AML cells ex vivo and regulates the levels of differentiation-related transcription factors
Jing Zhang, Jonathan S. Harrison, M. Uskoković, M. Danilenko +1 more
2009Hematological Oncology26 citations Open access
Semantic Scholar
Vitamin D Control of Hematopoietic Cell Differentiation and Leukemia
G. Studzinski, J. Harrison, Xue-Ning Wang, Surojit Sarkar +2 more
2015Journal of Cellular Biochemistry25 citations
Semantic Scholar
Novel Gemini analogs of 1α,25-dihydroxyvitamin D3 with enhanced transcriptional activity
F. Weyts, P. Dhawan, Xiaoyu Zhang, J. Bishop +5 more
200425 citations
Semantic Scholar
The requirement for and changing composition of the activating protein-1 transcription factor during differentiation of human leukemia HL60 cells induced by 1,25-dihydroxyvitamin D3.
Xue-Ning Wang, G. Studzinski
2006Cancer Research24 citations Open access
Semantic Scholar
1,25-DIHYDROXYVITAMIN D3 INDUCES MONOCYTIC DIFFERENTIATION OF HUMAN MYELOID LEUKEMIA CELLS BY REGULATING C/EBPβ EXPRESSION THROUGH MEF2C
Rui-Fang Zheng, Xue-Ning Wang, G. Studzinski
2014Journal of Steroid Biochemistry and Molecular Biology22 citations Open access
Semantic Scholar
The Potential of Vitamin D-Regulated Intracellular Signaling Pathways as Targets for Myeloid Leukemia Therapy
E. Gocek, G. Studzinski
2015Journal of Clinical Medicine20 citations Open access
Semantic Scholar
THE MAPK ERK5, BUT NOT ERK1/2, INHIBITS THE PROGRESSION OF MONOCYTIC PHENOTYPE TO THE FUNCTIONING MACROPHAGE
Xue-Ning Wang, Stella Pesakhov, J. Harrison, M. Kafka +2 more
2014Experimental Cell Research20 citations Open access
Semantic Scholar
Isoforms of p38MAPK gamma and delta contribute to differentiation of human AML cells induced by 1,25-dihydroxyvitamin D3
Jing Zhang, J. Harrison, G. Studzinski
2010Experimental Cell Research20 citations Open access
Semantic Scholar
Tumor suppressor p53 status does not determine the differentiation-associated G1 cell cycle arrest induced in leukemia cells by 1,25-dihydroxyvitamin D3 and antioxidants
Thelma O Thompson, M. Danilenko, L. Vassilev, G. Studzinski
201019 citations Open access
Semantic Scholar
hKSR-2, a vitamin D–regulated gene, inhibits apoptosis in arabinocytosine-treated HL60 leukemia cells
Xue-Ning Wang, Rahul K. Patel, G. Studzinski
2008Molecular Cancer Therapeutics19 citations Open access
Semantic Scholar
Role of vitamin D in regulating COVID-19 severity—An immunological perspective
Vandana Kalia, G. Studzinski, Surojit Sarkar
2021Journal of Leukocyte Biology17 citations Open access
Semantic Scholar
The role of VDR and BIM in potentiation of cytarabine–induced cell death in human AML blasts
J. Harrison, Xue-Ning Wang, G. Studzinski
2016OncoTarget17 citations Open access
Semantic Scholar
Differentiation-inducing potency of the seco-steroid JK-1624F2-2 can be increased by combination with an antioxidant and a p38MAPK inhibitor which upregulates the JNK pathway.
Jing Zhang, G. Posner, M. Danilenko, G. Studzinski
2007Journal of Steroid Biochemistry and Molecular Biology17 citations Open access
Semantic Scholar
Resistance to 1,25D‐induced differentiation in human acute myeloid leukemia HL60‐40AF cells is associated with reduced transcriptional activity and nuclear localization of the vitamin D receptor
E. Garay, R. Donnelly, Xue-Ning Wang, G. Studzinski
2007Journal of Cellular Physiology17 citations Open access
Semantic Scholar
Enhancement of Arabinocytosine (AraC) toxicity to AML cells by a differentiation agent combination
Xue-Ning Wang, J. Harrison, G. Studzinski
2015Journal of Steroid Biochemistry and Molecular Biology16 citations Open access
Semantic Scholar
Calcitriol derivatives with two different side-chains at C-20. Part 4: further chain modifications that alter VDR-dependent monocytic differentiation potency in human leukemia cells.
E. Garay, P. Jankowski, Paulo Lizano, S. Marczak +4 more
2007Bioorganic & Medicinal Chemistry15 citations Open access
Semantic Scholar
Dual role of hematopoietic progenitor kinase 1 (HPK1) as a positive regulator of 1α,25-dihydroxyvitamin D-induced differentiation and cell cycle arrest of AML cells and as a mediator of vitamin D resistance
Xiangwen Chen-Deutsch, G. Studzinski
2012Cell Cycle14 citations Open access
Semantic Scholar
Enhancement of sorafenib-mediated death of Hepatocellular carcinoma cells by Carnosic acid and Vitamin D2 analog combination.
Qunfeng Wu, Xue-Ning Wang, K. Pham, Aesis M. Luna +2 more
2019Journal of Steroid Biochemistry and Molecular Biology13 citations Open access
Semantic Scholar
The pan-caspase inhibitor QVD has anti-leukemia effects and can interact with vitamin D analogs to increase HPK1 signaling in AML cells
Xiangwen Chen-Deutsch, A. Kutner, J. Harrison, G. Studzinski
2012Leukemia research : a Forum for Studies on Leukemia and Normal Hemopoiesis13 citations Open access
Semantic Scholar

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Xue-Ning Wang×22
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Xue-Ning Wang — researcher profile on SciRah
M. Danilenko×15
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J. Harrison×12
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E. Gocek×10
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Jing Zhang — researcher profile on SciRah

M. Uskoković×6

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Stella Pesakhov×5

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M. Kafka — researcher profile on SciRah

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