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Chang-Zheng Chen · SciRah

Researcher profile · Semantic Scholar

Chang-Zheng Chen

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Chang-Zheng Chen — researcher profile on SciRah

h-index: 22
Works: 34
Citations: 11K

Most-cited papers

MicroRNAs Modulate Hematopoietic Lineage Differentiation
Chang-Zheng Chen, Ling Li, H. Lodish, D. Bartel
2004Science3,443 citations Open access
Semantic Scholar
MicroRNAs as oncogenes and tumor suppressors.
Chang-Zheng Chen
2005New England Journal of Medicine2,186 citations
Semantic Scholar
Micromanagers of gene expression: the potentially widespread influence of metazoan microRNAs
D. Bartel, Chang-Zheng Chen
2004Nature reviews genetics1,520 citations
Semantic Scholar
miR-181a is an intrinsic modulator of T cell sensitivity and selection.
Qi-Jing Li, J. Chau, Peter Ebert, Giselle Sylvester +9 more
2007Cell1,243 citations Open access
Semantic Scholar
Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture
Xing-Nan Li, L. Nadauld, A. Ootani, David C. Corney +17 more
2014Nature Medicine428 citations Open access
Semantic Scholar
Attribution of vascular phenotypes of the murine Egfl7 locus to the microRNA miR-126
F. Kuhnert, Michael R. Mancuso, J. Hampton, Kryn Stankunas +3 more
2008Development374 citations
Semantic Scholar
Micromanagement of the immune system by microRNAs
H. Lodish, Beiyan Zhou, Gwen Liu, Chang-Zheng Chen
2008Nature reviews. Immunology301 citations Open access
Semantic Scholar
Micromanagement of the immune system by microRNAs
H. Lodish, Beiyan Zhou, Gwen Liu, Chang-Zheng Chen
2008Nature reviews. Immunology214 citations
Semantic Scholar
MicroRNAs as regulators of mammalian hematopoiesis.
Chang-Zheng Chen, H. Lodish
2005Seminars in Immunology211 citations
Semantic Scholar
Identification of endoglin as a functional marker that defines long-term repopulating hematopoietic stem cells
Chang-Zheng Chen, Min Li, David de Graaf, S. Monti +6 more
2002Proceedings of the National Academy of Sciences of the United States of America178 citations Open access
Semantic Scholar
Regulation of immune responses and tolerance: the microRNA perspective
Chang-Zheng Chen, S. Schaffert, R. Fragoso, C. Loh
2013Immunological Reviews165 citations Open access
Semantic Scholar
Precise gene deletion and replacement using the CRISPR/Cas9 system in human cells.
Qiupeng Zheng, Xiao-Hong Cai, M. Tan, S. Schaffert +4 more
2014BioTechniques152 citations Open access
Semantic Scholar
Modulating the Strength and Threshold of NOTCH Oncogenic Signals by mir-181a-1/b-1
R. Fragoso, Tin Mao, Song Wang, S. Schaffert +8 more
2012PLoS Genetics134 citations Open access
Semantic Scholar
Pre-miRNA Loop Nucleotides Control the Distinct Activities of mir-181a-1 and mir-181c in Early T Cell Development
Gwen Liu, Hyeyoung Min, S. Yue, Chang-Zheng Chen
2008PLoS ONE129 citations Open access
Semantic Scholar
The potential functions of primary microRNAs in target recognition and repression
Robin Deis Trujillo, Si-biao Yue, Yu-Jie Tang, William E. O'Gorman +1 more
2010EMBO Journal75 citations Open access
Semantic Scholar
The EndoglinPositive Sca-1Positive RhodamineLow Phenotype Defines a Near-Homogeneous Population of Long-Term Repopulating Hematopoietic Stem Cells
Chang-Zheng Chen, Ling Li, Min Li, H. Lodish
200374 citations Open access
Semantic Scholar
MicroRNA programs in normal and aberrant stem and progenitor cells.
Christopher P. Arnold, R. Tan, Baiyu Zhou, Si-biao Yue +17 more
2011Genome Research62 citations Open access
Semantic Scholar
mir-181a-1/b-1 Modulates Tolerance through Opposing Activities in Selection and Peripheral T Cell Function
S. Schaffert, C. Loh, Song Wang, Christopher P. Arnold +7 more
2015Journal of Immunology46 citations Open access
Semantic Scholar
The endoglin(positive) sca-1(positive) rhodamine(low) phenotype defines a near-homogeneous population of long-term repopulating hematopoietic stem cells.
Chang-Zheng Chen, Ling Li, Min Li, H. Lodish
2003Immunity46 citations
Semantic Scholar
The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreas
K. Valencia, O. Erice, K. Kostyrko, Simone Hausmann +20 more
2019Journal of Clinical Investigation31 citations Open access
Semantic Scholar
Loop nucleotides control primary and mature miRNA function in target recognition and repression
Si-biao Yue, Robin Deis Trujillo, Yu-Jie Tang, William E. O'Gorman +1 more
2011RNA Biology28 citations Open access
Semantic Scholar
microRNAs Regulate Cell-to-Cell Variability of Endogenous Target Gene Expression in Developing Mouse Thymocytes
R. Blevins, L. Bruno, Thomas L. Carroll, J. Elliott +8 more
2015PLoS Genetics23 citations Open access
Semantic Scholar
An Unsolved Mystery: The Target-Recognizing RNA Species of MicroRNA Genes
Chang-Zheng Chen
2013Biochimie16 citations Open access
Semantic Scholar
Dissecting microRNA-mediated gene regulation and function in T-cell development.
Tin Mao, Chang-Zheng Chen
2007Methods in Enzymology14 citations
Semantic Scholar
Methods for analyzing microRNA expression and function during hematopoietic lineage differentiation.
Hyeyoung Min, Chang-Zheng Chen
2006Methods in molecular biology8 citations
Semantic Scholar
LncRNA XIST Promotes Proliferation, Migration and Invasion of Esophageal Squamous Cell Carcinoma Cells via Regulation of miR-186-5p/ZEB1
Yun-yun Ma, Lili Qian, Dechao Wang, Chang-Zheng Chen
2025Anticancer Research4 citations Open access
Semantic Scholar
The Mir-17-19b Microrna Cluster Quantitatively Regulates the Self- Renewing Leukemia Stem Cell Compartment in MLL Leukemia
Piu Wong, M. Iwasaki, Chang-Zheng Chen, M. Cleary
20084 citations
Semantic Scholar
Editorial Expression of Concern: Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture.
Xing-Nan Li, L. Nadauld, A. Ootani, David C. Corney +17 more
2026Nature Medicine0 citations Open access
Semantic Scholar
This information is current as Peripheral T Cell Function Opposing Activities in Selection and Modulates Tolerance through mir-181 a-1 / b-1
S. Schaffert, C. Loh, Song Wang, Christopher P. Arnold +7 more
20150 citations
Semantic Scholar
Regulation of selection and autoimmunity by miR-181 family miRNAs (123.36)
S. Schaffert, Song Wang, R. Axtell, E. Newell +3 more
2012Journal of Immunology0 citations
Semantic Scholar
cells MicroRNA programs in normal and aberrant stem and progenitor Material Supplemental
Christopher P. Arnold, R. Tan, Baiyu Zhou, Si-biao Yue +17 more
20110 citations
Semantic Scholar
Essential Role for Mir-181a1/b1 In T-Cell Acute Lymphoblastic Leukemia
A. Fragoso, Tin Mao, Song Wang, S. Schaffert +3 more
20100 citations
Semantic Scholar
Aberrant expression of miR-196b and miR-708 is characteristic for but not reflecting the differentiation status of MLL-rearranged and T-cell acute lymphoblastic leukemia in children.
D. Schotte, M. Broekhuis, V. V. D. van der Velden, R. Pieters +2 more
20080 citations
Semantic Scholar
MiRNA Profiles in Acute Lymphoblastic Leukemia: Rather a Characteristic for the Leukemia Subtype Than a Reflection of Its Differentiation Status.
D. Schotte, M. Broekhuis, M. Jansen, R. Pieters +2 more
20070 citations
Semantic Scholar
Unique MicroRNA Profiles in Childhood Acute Lymphoblastic Leukemia.
D. Schotte, J. Chau, Giselle Sylvester, Gwen Liu +4 more
20060 citations
Semantic Scholar

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