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J. Lindon · SciRah

Researcher profile · Semantic Scholar

J. Lindon

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J. Lindon — researcher profile on SciRah

h-index: 104
Works: 556
Citations: 52K

Most-cited papers

Precision high-throughput proton NMR spectroscopy of human urine, serum, and plasma for large-scale metabolic phenotyping.
A. Dona, B. Jiménez, H. Schäfer, E. Humpfer +6 more
2014Analytical Chemistry526 citations
Semantic Scholar
Metabolic phenotyping in clinical and surgical environments
J. Nicholson, E. Holmes, J. Kinross, A. Darzi +2 more
2012Nature515 citations
Semantic Scholar
Colonization-Induced Host-Gut Microbial Metabolic Interaction
Sandrine P. Claus, S. Ellero, B. Berger, L. Krause +16 more
2011mBio406 citations Open access
Semantic Scholar
Quantitative Lipoprotein Subclass and Low Molecular Weight Metabolite Analysis in Human Serum and Plasma by 1H NMR Spectroscopy in a Multilaboratory Trial.
B. Jiménez, E. Holmes, C. Heude, R. Tolson +12 more
2018Analytical Chemistry219 citations Open access
Semantic Scholar
Serum metabolic signatures of coronary and carotid atherosclerosis and subsequent cardiovascular disease
I. Tzoulaki, R. Castagné, C. Boulangé, I. Karaman +28 more
2019European Heart Journal170 citations Open access
Semantic Scholar
Robust data processing and normalization strategy for MALDI mass spectrometric imaging.
J. M. Fonville, C. Carter, O. Cloarec, J. Nicholson +3 more
2012Analytical Chemistry137 citations Open access
Semantic Scholar
Pharmacometabonomics as an effector for personalized medicine.
J. Nicholson, I. Wilson, J. Lindon
2011Pharmacogenomics (London)134 citations
Semantic Scholar
Development and Application of Ultra-Performance Liquid Chromatography-TOF MS for Precision Large Scale Urinary Metabolic Phenotyping.
Matthew R. Lewis, Jake T. M. Pearce, K. Spagou, M. Green +15 more
2016Analytical Chemistry128 citations Open access
Semantic Scholar
Stability and robustness of human metabolic phenotypes in response to sequential food challenges.
S. Heinzmann, C. Merrifield, S. Rezzi, S. Kochhar +3 more
2012Journal of Proteome Research126 citations Open access
Semantic Scholar
A metabolic system-wide characterisation of the pig: a model for human physiology.
C. Merrifield, Marie Lewis, Sandrine P. Claus, O. Beckonert +8 more
2011Molecular Biosystems123 citations
Semantic Scholar
Hyperspectral visualization of mass spectrometry imaging data.
J. M. Fonville, C. Carter, Luis Pizarro, R. Steven +7 more
2013Analytical Chemistry112 citations
Semantic Scholar
Identification of human urinary biomarkers of cruciferous vegetable consumption by metabonomic profiling.
W. Edmands, O. Beckonert, C. Stella, A. Campbell +4 more
2011Journal of Proteome Research110 citations Open access
Semantic Scholar
Incomplete Systemic Recovery and Metabolic Phenoreversion in Post-Acute-Phase Nonhospitalized COVID-19 Patients: Implications for Assessment of Post-Acute COVID-19 Syndrome
E. Holmes, Julien Wist, R. Masuda, S. Lodge +23 more
2021Journal of Proteome Research108 citations Open access
Semantic Scholar
UPLC-MS metabolic profiling of second trimester amniotic fluid and maternal urine and comparison with NMR spectral profiling for the identification of pregnancy disorder biomarkers.
G. Graça, B. Goodfellow, António S. Barros, Sílvia O. Diaz +9 more
2012Molecular Biosystems97 citations
Semantic Scholar
Identifying unknown metabolites using NMR-based metabolic profiling techniques
I. García-Pérez, J. Posma, J. Serrano-Contreras, C. Boulangé +7 more
2020Nature Protocols88 citations
Semantic Scholar
The emergent role of metabolic phenotyping in dynamic patient stratification
J. Lindon, J. Nicholson
2014Expert Opinion on Drug Metabolism & Toxicology76 citations
Semantic Scholar
Subset optimization by reference matching (STORM): an optimized statistical approach for recovery of metabolic biomarker structural information from 1H NMR spectra of biofluids.
J. Posma, I. García-Pérez, M. D. De Iorio, J. Lindon +4 more
2012Analytical Chemistry75 citations
Semantic Scholar
Statistical spectroscopic tools for biomarker discovery and systems medicine.
S. Robinette, J. Lindon, J. Nicholson
2013Analytical Chemistry74 citations
Semantic Scholar
NMR Spectroscopic Windows on the Systemic Effects of SARS-CoV-2 Infection on Plasma Lipoproteins and Metabolites in Relation to Circulating Cytokines.
S. Lodge, P. Nitschke, Torben Kimhofer, J. D. Coudert +11 more
2021Journal of Proteome Research73 citations Open access
Semantic Scholar
Targeting the human genome-microbiome axis for drug discovery: inspirations from global systems biology and traditional Chinese medicine.
Li-Ping Zhao, J. Nicholson, Ai-Ping Lu, Zhengtao Wang +6 more
2012Journal of Proteome Research64 citations
Semantic Scholar
Longitudinal pharmacometabonomics for predicting patient responses to therapy: drug metabolism, toxicity and efficacy
J. Nicholson, J. Everett, J. Lindon
2012Expert Opinion on Drug Metabolism & Toxicology64 citations Open access
Semantic Scholar
Omics and its potential impact on R&D and regulation of complex herbal products.
O. Pelkonen, M. Pasanen, J. Lindon, Kelvin Chan +4 more
2012Journal of Ethnopharmacology61 citations Open access
Semantic Scholar
The urinary proteome and metabonome differ from normal in adults with mitochondrial disease.
A. Hall, A. Vilasi, I. García-Pérez, M. Lapsley +15 more
2015Kidney International57 citations Open access
Semantic Scholar
Diffusion and Relaxation Edited Proton NMR Spectroscopy of Plasma Reveals a High-Fidelity Supramolecular Biomarker Signature of SARS-CoV-2 Infection
S. Lodge, P. Nitschke, Torben Kimhofer, Julien Wist +12 more
2021Analytical Chemistry54 citations Open access
Semantic Scholar
Quantitative In-Vitro Diagnostic NMR Spectroscopy for Lipoprotein and Metabolite Measurements in Plasma and Serum: Recommendations for Analytical Artifact Minimization with Special Reference to COVID-19/SARS-CoV-2 Samples
R. Loo, S. Lodge, Torben Kimhofer, Sze-How Bong +11 more
2020Journal of Proteome Research50 citations Open access
Semantic Scholar
Integrated Analytical and Statistical Two-Dimensional Spectroscopy Strategy for Metabolite Identification: Application to Dietary Biomarkers
J. Posma, I. García-Pérez, J. Heaton, P. Burdisso +7 more
2017Analytical Chemistry50 citations Open access
Semantic Scholar
Intra- and interlaboratory reproducibility of ultra performance liquid chromatography-time-of-flight mass spectrometry for urinary metabolic profiling.
H. Benton, E. Want, H. Keun, A. Amberg +8 more
2012Analytical Chemistry49 citations
Semantic Scholar
Data-driven approach for metabolite relationship recovery in biological 1H NMR data sets using iterative statistical total correlation spectroscopy.
Caroline J. Sands, Muireann Coen, T. Ebbels, E. Holmes +2 more
2011Analytical Chemistry42 citations
Semantic Scholar
A comparison of human serum and plasma metabolites using untargeted 1H NMR spectroscopy and UPLC-MS
M. Kaluarachchi, C. Boulangé, I. Karaman, J. Lindon +4 more
2018Metabolomics41 citations Open access
Semantic Scholar
Workflow for Integrated Processing of Multicohort Untargeted 1H NMR Metabolomics Data in Large-Scale Metabolic Epidemiology.
I. Karaman, D. S. Ferreira, C. Boulangé, M. Kaluarachchi +15 more
2016Journal of Proteome Research41 citations Open access
Semantic Scholar
Optimized Phenotypic Biomarker Discovery and Confounder Elimination via Covariate-Adjusted Projection to Latent Structures from Metabolic Spectroscopy Data
J. Posma, I. García-Pérez, T. Ebbels, J. Lindon +4 more
2018Journal of Proteome Research40 citations Open access
Semantic Scholar
Evaluation of high resolution magic-angle coil spinning NMR spectroscopy for metabolic profiling of nanoliter tissue biopsies.
A. Wong, B. Jiménez, Xiao-Nan Li, E. Holmes +3 more
2012Analytical Chemistry38 citations
Semantic Scholar
Chiral metabonomics: 1H NMR-based enantiospecific differentiation of metabolites in human urine via direct cosolvation with β-cyclodextrin.
M. Pérez-Trujillo, J. Lindon, T. Parella, H. Keun +2 more
2012Analytical Chemistry35 citations Open access
Semantic Scholar
Pharmacometabonomic investigation of dynamic metabolic phenotypes associated with variability in response to galactosamine hepatotoxicity.
Muireann Coen, F. Goldfain-Blanc, G. Rolland-Valognes, B. Walther +4 more
2012Journal of Proteome Research35 citations
Semantic Scholar
Pharmacometabonomic characterization of xenobiotic and endogenous metabolic phenotypes that account for inter-individual variation in isoniazid-induced toxicological response.
Katharine Cunningham, Sandrine P. Claus, J. Lindon, E. Holmes +3 more
2012Journal of Proteome Research34 citations
Semantic Scholar
J-Edited DIffusional Proton Nuclear Magnetic Resonance Spectroscopic Measurement of Glycoprotein and Supramolecular Phospholipid Biomarkers of Inflammation in Human Serum.
P. Nitschke, S. Lodge, Torben Kimhofer, R. Masuda +16 more
2022Analytical Chemistry32 citations Open access
Semantic Scholar
Low Volume in Vitro Diagnostic Proton NMR Spectroscopy of Human Blood Plasma for Lipoprotein and Metabolite Analysis: Application to SARS-CoV-2 Biomarkers
S. Lodge, P. Nitschke, R. Loo, Torben Kimhofer +8 more
2021Journal of Proteome Research31 citations Open access
Semantic Scholar
Can joint fluid metabolic profiling (or “metabonomics”) reveal biomarkers for osteoarthritis and inflammatory joint disease?
P. Akhbari, U. Karamchandani, M. Jaggard, G. Graça +4 more
2020Bone & Joint Research28 citations Open access
Semantic Scholar
A Unified Conceptual Framework for Metabolic Phenotyping in Diagnosis and Prognosis.
J. Everett, E. Holmes, K. Veselkov, J. Lindon +1 more
2019TIPS - Trends in Pharmacological Sciences28 citations Open access
Semantic Scholar
Statistical total correlation spectroscopy scaling for enhancement of metabolic information recovery in biological NMR spectra.
A. D. Maher, J. M. Fonville, Muireann Coen, J. Lindon +2 more
2012Analytical Chemistry28 citations
Semantic Scholar
Untargeted metabolome quantitative trait locus mapping associates variation in urine glycerate to mutant glycerate kinase.
J. Cazier, P. Kaisaki, K. Argoud, B. Blaise +12 more
2012Journal of Proteome Research27 citations Open access
Semantic Scholar
Improving Visualization and Interpretation of Metabolome-Wide Association Studies: An Application in a Population-Based Cohort Using Untargeted 1H NMR Metabolic Profiling
R. Castagné, C. Boulangé, I. Karaman, G. Campanella +16 more
2017Journal of Proteome Research26 citations Open access
Semantic Scholar
Multiplatform serum metabolic phenotyping combined with pathway mapping to identify biochemical differences in smokers.
M. Kaluarachchi, C. Boulangé, I. García-Pérez, J. Lindon +1 more
2016Bioanalysis26 citations Open access
Semantic Scholar
Exploration of Human Serum Lipoprotein Supramolecular Phospholipids Using Statistical Heterospectroscopy in n-Dimensions (SHY-n): Identification of Potential Cardiovascular Risk Biomarkers Related to SARS-CoV-2 Infection.
R. Masuda, S. Lodge, L. Whiley, N. Gray +20 more
2022Analytical Chemistry24 citations Open access
Semantic Scholar
A systematic review of the small molecule studies of osteoarthritis using nuclear magnetic resonance and mass spectroscopy.
M. Jaggard, C. Boulangé, P. Akhbari, U. Vaghela +4 more
2019Osteoarthritis and Cartilage22 citations Open access
Semantic Scholar
J-Resolved 1H NMR 1D-Projections for Large-Scale Metabolic Phenotyping Studies: Application to Blood Plasma Analysis.
A. Rodriguez-Martinez, J. Posma, R. Ayala, Nikita Harvey +10 more
2017Analytical Chemistry20 citations
Semantic Scholar
Application of CE-MS to a metabonomics study of human urine from cigarette smokers and non-smokers.
I. García-Pérez, J. Lindon, E. Minet
2014Bioanalysis19 citations
Semantic Scholar
Topological analysis of metabolic networks integrating co-segregating transcriptomes and metabolomes in type 2 diabetic rat congenic series
M. Dumas, C. Domange, S. Calderari, Andrea Rodriguez Martinez +17 more
2016Genome Medicine17 citations Open access
Semantic Scholar
Differences in the composition of hip and knee synovial fluid in osteoarthritis: a nuclear magnetic resonance (NMR) spectroscopy study of metabolic profiles.
P. Akhbari, M. Jaggard, C. Boulangé, U. Vaghela +5 more
2019Osteoarthritis and Cartilage16 citations Open access
Semantic Scholar
Integrated Histopathological and Urinary Metabonomic Investigation of the Pathogenesis of Microcystin-LR Toxicosis
G. Cantor, O. Beckonert, M. Bollard, Hector C. Keun +9 more
2013Veterinary Pathology-Supplement15 citations Open access
Semantic Scholar

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